Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_054732380.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_054735157.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054730293.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054743356.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901	"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"VLDL assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"LDL remodeling";"Chylomicron remodeling"
XP_054730318.1	4	MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism"
XP_054726249.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_054733502.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054731710.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-432142	"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL"
XP_054731272.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054734022.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_054732586.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054741356.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054728159.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054731894.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-2173796	"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_054738827.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054733710.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465	"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins"
XP_054731502.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054739082.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054726501.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262	"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_054738494.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_054738549.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054744757.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054727186.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes"
XP_054744122.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_054747612.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054741601.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054734517.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054738166.1	13	MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7721	"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_054733427.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054742448.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_054735232.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054733218.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742113.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis"
XP_054741766.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054731484.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;MetaCyc: PWY-6799;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-6282;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-7723;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWY-5142;MetaCyc: PWY-8049;Reactome: R-HSA-9029558;MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-7746;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-5367;Reactome: R-HSA-163765	"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Petroselinate biosynthesis";"ChREBP activates metabolic gene expression"
XP_054736354.1	6	KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6367;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64+3.1.3.95	"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system"
XP_054725987.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054728197.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054736988.1	5	KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054747170.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA"
XP_054731800.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_054732403.1	6	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-3371453;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of HSF1-mediated heat shock response";"Citrate cycle (TCA cycle)"
XP_054725454.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726470.1	6	KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347	"Vitamin B6 metabolism";"Methane metabolism";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis"
XP_054727864.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054744367.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054728565.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_054738884.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054737537.1	83	Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-2871796;Reactome: R-HSA-9634285;Reactome: R-HSA-8983432;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-1250347;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-9645135;Reactome: R-HSA-167044;Reactome: R-HSA-8851907;Reactome: R-HSA-5654733;Reactome: R-HSA-8856825;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-180336;Reactome: R-HSA-74751;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5654720;Reactome: R-HSA-1963640;Reactome: R-HSA-9028335;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-8853659;Reactome: R-HSA-375165;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-1250196;Reactome: R-HSA-512988;Reactome: R-HSA-6807004;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-9026519;Reactome: R-HSA-5654726;Reactome: R-HSA-2871809;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-5654727;Reactome: R-HSA-9664565;Reactome: R-HSA-5655253;Reactome: R-HSA-1839117;Reactome: R-HSA-5654704;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-8856828;Reactome: R-HSA-180292;Reactome: R-HSA-5663213;Reactome: R-HSA-5654699;Reactome: R-HSA-186763;Reactome: R-HSA-74749;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-5654719;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-8851805;Reactome: R-HSA-391160;Reactome: R-HSA-389359;Reactome: R-HSA-2730905;Reactome: R-HSA-8875656;Reactome: R-HSA-1257604;Reactome: R-HSA-1295596;Reactome: R-HSA-210993;Reactome: R-HSA-9027284;Reactome: R-HSA-912631;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689	"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FCERI mediated MAPK activation";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin-15 signaling";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PI3K Cascade";"SHC1 events in ERBB4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"STAT5 Activation";"Signalling to RAS";"MET activates PI3K/AKT signaling";"Negative regulation of FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"SHC1 events in EGFR signaling";"Insulin receptor signalling cascade";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR4";"GRB2 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"FLT3 Signaling";"EGFR downregulation";"RET signaling";"NCAM signaling for neurite out-growth";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"SHC1 events in ERBB2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Negative regulation of MET activity";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR1 signaling";"FCERI mediated Ca+2 mobilization";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR2 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"SHC-mediated cascade:FGFR3";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"Clathrin-mediated endocytosis";"GAB1 signalosome";"RHO GTPases Activate WASPs and WAVEs";"SHC-mediated cascade:FGFR2";"Downstream signal transduction";"Signal attenuation";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR4";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"MET activates RAS signaling";"Signal regulatory protein family interactions";"CD28 dependent Vav1 pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"MET receptor recycling";"PIP3 activates AKT signaling";"Spry regulation of FGF signaling";"Tie2 Signaling";"Erythropoietin activates RAS";"Regulation of signaling by CBL";"MET activates PTPN11";"PI-3K cascade:FGFR1"
XP_054745061.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054727753.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054737070.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054727242.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054730738.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054744216.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054741643.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054738127.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_054733466.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054738752.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_054737649.1	13	MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I"
XP_054743643.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054725129.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054735068.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054735857.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054741784.1	6	Reactome: R-HSA-70221;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6731	"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation III"
XP_054740337.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123	"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis"
XP_054742235.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054743211.1	13	MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_054734677.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054740438.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054737368.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_054741094.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054738866.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054726543.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054730561.1	8	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTOR signaling pathway"
XP_054729576.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236	"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"snRNP Assembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054733695.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054726389.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054729199.1	4	MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_054747572.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054731695.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_054742287.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054739935.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_054743968.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054747236.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_054727382.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054747870.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_054736786.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054738637.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054735616.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054731608.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751	"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated"
XP_054732564.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054741410.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054743237.1	3	KEGG: 00230+1.7.3.3;KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691	"Purine metabolism";"Caffeine metabolism";"Urate conversion to allantoin I"
XP_054741968.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054741285.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26	"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism"
XP_054734984.1	15	Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9665246;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565	"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants"
XP_054741000.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054738685.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054740717.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735994.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054738184.1	33	Reactome: R-HSA-73863;Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-69202;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Termination";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"mRNA Capping";"Dual incision in TC-NER"
XP_054730936.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054745277.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054734889.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"ECM proteoglycans";"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054741321.1	10	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_054739063.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_054734457.1	9	KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis"
XP_054743693.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054729917.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054726806.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054740922.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054731817.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054736055.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054741693.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054726077.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054739559.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054727839.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038	"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions"
XP_054741138.1	7	Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_054726530.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054738318.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_054729171.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_054738417.1	34	Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9648025	"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation"
XP_054745178.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054743044.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway"
XP_054741630.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054730549.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_054738876.1	18	Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-113418	"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex"
XP_054737378.1	13	Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-450321	"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_054741044.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_054726593.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054731038.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054733645.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054732088.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_054739664.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054732647.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054741978.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054734306.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054743628.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054732491.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-380284	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054736229.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054734270.1	6	Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism"
XP_054747860.1	5	MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_054741628.1	24	Reactome: R-HSA-5610787;Reactome: R-HSA-5687128;Reactome: R-HSA-392517;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-163358;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-5610780;Reactome: R-HSA-111931;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-432040;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8853659;Reactome: R-HSA-381676	"Hedgehog 'off' state";"MAPK6/MAPK4 signaling";"Rap1 signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of key metabolic factors";"HDL assembly";"Triglyceride catabolism";"Degradation of GLI1 by the proteasome";"PKA-mediated phosphorylation of CREB";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"mTOR signaling pathway";"RET signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054731656.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054737312.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944	"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2"
XP_054736739.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_054726832.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054739073.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_054734651.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054732815.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054726528.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054728529.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054728615.1	5	MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054735944.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054726302.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-7901	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine"
XP_054729527.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054732181.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_054731844.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054744002.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054744658.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054743308.1	9	MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-6471;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6470	"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_054737116.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054731117.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_054728298.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695	"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation"
XP_054733117.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054726299.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801	"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion"
XP_054744150.1	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_054730611.1	6	MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906	"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Galactose metabolism";"Chitin derivatives degradation"
XP_054742498.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054731949.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_054747016.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054725664.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054738444.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-200425	"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Carnitine metabolism"
XP_054743407.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)"
XP_054738599.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054729012.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054726622.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054738561.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733971.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054742359.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054742015.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054735149.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054730637.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_054736505.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054735360.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054740084.1	20	MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403	"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Mitochondrial protein import";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)"
XP_054747371.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_054735566.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741776.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735258.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054743395.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054741820.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302	"HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome"
XP_054747668.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054745736.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6364;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_054745049.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054732115.1	12	Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Rho GTPase cycle";"G alpha (q) signalling events";"mTOR signaling pathway";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events"
XP_054726460.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054727874.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054746263.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054741395.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054725559.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape"
XP_054746526.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054740364.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054747448.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054736266.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054736101.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054735919.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane"
XP_054739293.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG";"Ether lipid metabolism";"Role of phospholipids in phagocytosis"
XP_054726640.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex"
XP_054741765.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054733587.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054735147.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs"
XP_054745180.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054728258.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580	"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Oxidative Stress Induced Senescence"
XP_054746411.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_054726148.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054737380.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054733773.1	6	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_054727977.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_054744133.1	58	Reactome: R-HSA-5362768;Reactome: R-HSA-5689901;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Metalloprotease DUBs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054737955.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054730514.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054732070.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054743264.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054742678.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054734004.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054726413.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054732537.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_054731947.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_054741980.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054727252.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-2871796;Reactome: R-HSA-114604	"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade"
XP_054732585.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054734288.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418217	"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta"
XP_054737403.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054740029.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054740754.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054743980.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054739372.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054743019.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054727743.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054725176.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054741264.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_054725902.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054729615.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054729529.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054735313.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
XP_054737425.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4"
XP_054738073.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_054742767.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"MAP2K and MAPK activation";"mTORC1-mediated signalling"
XP_054726297.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054733119.1	4	Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695	"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"HS-GAG degradation";"Neutrophil degranulation"
XP_054745291.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054741286.1	5	KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782	"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_054730454.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054747703.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis"
XP_054745404.1	7	MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_054736785.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054728527.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054725738.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054747235.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_054744833.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_054728871.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054728012.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054729704.1	26	Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695	"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"SUMOylation of transcription cofactors";"Attenuation phase";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_054732671.1	4	KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_054728402.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054739599.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054732649.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054741653.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054739444.1	16	Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-5602680;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-975138	"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_054744281.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_054725372.1	57	Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-180585;Reactome: R-HSA-8939902	"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity"
XP_054727495.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Signal transduction by L1";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Regulation of PTEN stability and activity"
XP_054744303.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054745433.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631	"Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL"
XP_054730924.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054725876.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054736652.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054732758.1	6	Reactome: R-HSA-173599;MetaCyc: PWY-7346;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22	"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism"
XP_054727408.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_054740163.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054730674.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054741142.1	7	Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828	"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis"
XP_054733465.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054734669.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054747734.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_054727018.1	9	Reactome: R-HSA-416476;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052	"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis"
XP_054744909.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054733819.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198	"Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis"
XP_054730175.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054729205.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054729919.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054727701.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054737564.1	2	KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054747224.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054727837.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions"
XP_054725720.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733696.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054730063.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054744804.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054731819.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054742870.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054742236.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054738082.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054727676.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins"
XP_054739827.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054732378.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_054736462.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054740719.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054744840.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_054744982.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_054742562.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_054730559.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054738639.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054728616.1	5	MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054733154.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_054739201.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054732732.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054732816.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054725362.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725637.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_054734323.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_054739571.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054732477.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054739494.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054728861.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054732706.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria"
XP_054736056.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054740904.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_054740173.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054726805.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_054735954.1	11	Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781	"Nuclear Receptor transcription pathway";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression"
XP_054736970.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054731475.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054732657.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_054738129.1	7	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054726091.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_054731092.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_054728857.1	24	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Aggrephagy";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_054730073.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054734213.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054745440.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054737574.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054737647.1	13	MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-5122	"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis"
XP_054740339.1	13	MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7141	"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis"
XP_054743463.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054735859.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054745225.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054727728.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054741775.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735565.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054736506.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054734187.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_054729859.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054747498.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054737539.1	83	Reactome: R-HSA-2871796;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-5673001;Reactome: R-HSA-8853338;Reactome: R-HSA-5654732;Reactome: R-HSA-2424491;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285;Reactome: R-HSA-9028731;Reactome: R-HSA-2029482;Reactome: R-HSA-1250347;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-9645135;Reactome: R-HSA-167044;Reactome: R-HSA-983695;Reactome: R-HSA-8853334;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-8856825;Reactome: R-HSA-5654720;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640;Reactome: R-HSA-512988;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-5654710;Reactome: R-HSA-6807004;Reactome: R-HSA-1839117;Reactome: R-HSA-5655253;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-5654699;Reactome: R-HSA-180292;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-5654704;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-5654719;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-912631;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-5654689;Reactome: R-HSA-8865999	"FCERI mediated MAPK activation";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"RAF/MAP kinase cascade";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR3 signaling";"DAP12 signaling";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of actin dynamics for phagocytic cup formation";"SHC1 events in ERBB4 signaling";"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"STAT5 Activation";"Signalling to RAS";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR4";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"NCAM signaling for neurite out-growth";"RET signaling";"FLT3 Signaling";"EGFR downregulation";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"PI-3K cascade:FGFR3";"Negative regulation of MET activity";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR2 in disease";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"SHC-mediated cascade:FGFR2";"GAB1 signalosome";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Signal attenuation";"Downstream signal transduction";"Signal regulatory protein family interactions";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"SHC-mediated cascade:FGFR4";"PIP3 activates AKT signaling";"MET receptor recycling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"Regulation of signaling by CBL";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling";"PI-3K cascade:FGFR1";"MET activates PTPN11"
XP_054734135.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054744369.1	42	Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-5625886;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-977225;Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Amyloid fiber formation";"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression"
XP_054742406.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054744797.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054736830.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_054728206.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_054733763.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_054738935.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_054741590.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054745203.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054744087.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054741396.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054745381.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_054734040.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_054727421.1	11	MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2	"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_054743396.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054736893.1	10	KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781	"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression"
XP_054747888.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis"
XP_054725201.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054739685.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_054745315.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_054741274.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054738547.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054739362.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054745059.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054727793.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_054734519.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054725571.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_054742668.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_054725494.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054739637.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054747423.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054736532.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054734124.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054730865.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054738063.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_054727730.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054726247.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054725827.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_054744963.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054736394.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054735248.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_054742432.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054747015.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054728157.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054727951.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400	"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054729424.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054727083.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006	"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_054726604.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_054745335.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054730342.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054747140.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809	"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization"
XP_054744953.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054737135.1	17	Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2	"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Aflatoxin biosynthesis"
XP_054734539.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054740598.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_054739617.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054736027.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054745805.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054747391.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054735340.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744769.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054725156.1	26	Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"HCMV Early Events";"Recycling pathway of L1";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases activate IQGAPs"
XP_054747648.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054736512.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_054743375.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054727710.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054732626.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054742412.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054732050.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5	"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes"
XP_054734181.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054728508.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054728151.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_054727800.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054726509.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054729005.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_054731864.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054743513.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_054728278.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_054727536.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054742749.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054726241.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_054725821.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054729964.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054727330.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054734996.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054740523.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560	"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II"
XP_054730263.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741609.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054731969.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_054742478.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054729023.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054726992.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054738196.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054738541.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054732136.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (q) signalling events";"mTOR signaling pathway";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054729869.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054730846.1	3	MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099	"L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling"
XP_054743609.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054744359.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054727393.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952	"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions"
XP_054740505.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_054739030.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054746383.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054725631.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054742850.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054739577.1	14	MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_054729555.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_054731886.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_054727695.1	12	MetaCyc: PWY-5857;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5870	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_054737459.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054743998.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Photosynthesis";"Insulin receptor recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Ion channel transport"
XP_054735869.1	24	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-354192;Reactome: R-HSA-6804757;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-444257	"Relaxin signaling pathway";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Integrin signaling";"Regulation of TP53 Degradation";"Activation of AKT2";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"RSK activation"
XP_054734881.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054741329.1	10	Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23	"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism"
XP_054735415.1	5	Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-983168	"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054734233.1	7	MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-7282;MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism"
XP_054743329.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054735964.1	14	Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897	"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes"
XP_054735481.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054737679.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054733164.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_054740046.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_054725352.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054733496.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054743923.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054732651.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054745633.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054728636.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054741905.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054741219.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_054726381.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054736618.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054732836.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_054733382.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054727608.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054732306.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054730591.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_054732500.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054740229.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054734469.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization"
XP_054727052.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation"
XP_054726573.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054737398.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_054735879.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_054728416.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_054727645.1	18	MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PI";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_054725485.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054728006.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_054732927.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression"
XP_054747714.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741948.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054732499.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054747325.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054742538.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054744235.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7727;MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_054732544.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_054730981.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054732677.1	15	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054733839.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054739916.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054735103.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054736950.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism"
XP_054735974.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_054727817.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_054739043.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054733455.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054733309.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054742216.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054733446.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054739108.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054739551.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054727831.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_054725320.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054740642.1	12	KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13	"Methane metabolism";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_054735635.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054732889.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9	"Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis"
XP_054731446.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054740096.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054734748.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054733903.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054735048.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054729803.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_054747909.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054747215.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054738846.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054728032.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733675.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054739600.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054730464.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054743074.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_054733925.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054729825.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054742326.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054725600.1	3	KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3	"Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism"
XP_054731581.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054730534.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054727971.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054738155.1	13	MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I"
XP_054733373.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054732517.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741746.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054747747.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054742122.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_054728760.1	15	Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-8853884	"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX"
XP_054742757.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054747190.1	13	Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427	"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation"
XP_054731373.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054743039.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_054746318.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054727844.1	12	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor"
XP_054729635.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054741365.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054746293.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_054736107.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054729048.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054730486.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_054742606.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054743365.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054745079.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054732966.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_054734380.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_054745041.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054728985.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054742799.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054725195.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054736683.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054742761.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054732189.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054737288.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054731874.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054726014.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054739808.1	20	Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054740354.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054735834.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_054736568.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747104.1	4	Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377	"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_054733941.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_054729841.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation"
XP_054746431.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054729879.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054730619.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054742468.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741755.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_054744113.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054731941.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282	"Pyridoxal 5'-phosphate salvage II (plants)";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_054741294.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_054734995.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054729877.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054727535.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054747658.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054727773.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_054747412.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_054725474.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_054727587.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054729006.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054729416.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054741011.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741872.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737976.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054730121.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749	"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs"
XP_054733111.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054728713.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_054740300.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054738195.1	6	KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054726938.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054735985.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054744943.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054743708.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054741795.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054728803.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054744583.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054740532.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_054727119.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054737136.1	17	MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780	"Glyoxylate assimilation";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism"
XP_054742963.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054725654.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054743818.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054739263.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199	"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_054736109.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054733137.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054744371.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735911.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138	"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_054725282.1	7	Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346	"Activation of SMO";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis"
XP_054738551.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054745077.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054741570.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-4570464	"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins"
XP_054730631.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_054731684.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054733252.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_054747749.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_054727947.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054747771.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_054732625.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054747377.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_054733684.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054738600.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174113	"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1"
XP_054736873.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054730762.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054743037.1	7	Reactome: R-HSA-9018896;Reactome: R-HSA-9020265;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676;Reactome: R-HSA-6798695;Reactome: R-HSA-9023661	"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(R)-resolvins"
XP_054743376.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_054727524.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction"
XP_054742759.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054742024.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054731743.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725155.1	26	Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-389977;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148	"Gap junction assembly";"RHO GTPases activate IQGAPs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Post-chaperonin tubulin folding pathway";"MHC class II antigen presentation";"HCMV Early Events";"Cilium Assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735177.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_054740193.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_054745257.1	13	Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184	"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054736990.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054739155.1	8	MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;MetaCyc: PWY-5723;Reactome: R-HSA-6791055	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_054740045.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_054730207.1	5	Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054730783.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054731072.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054737332.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054734222.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054740462.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054731811.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054726812.1	11	MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-5497;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-5695;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6538	"Guanosine nucleotides degradation II";"Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)"
XP_054732887.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_054733666.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_054732305.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes"
XP_054740130.1	5	Reactome: R-HSA-5083630;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399	"Defective LFNG causes SCDO3";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_054742840.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_054737594.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054739282.1	7	MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4	"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Ether lipid metabolism"
XP_054733072.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054741906.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727709.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054725263.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_054732398.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054737500.1	13	Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-8876725;Reactome: R-HSA-5678895;Reactome: R-HSA-5689896	"Hedgehog ligand biogenesis";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"HSF1 activation";"Josephin domain DUBs";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Protein methylation";"Defective CFTR causes cystic fibrosis";"Ovarian tumor domain proteases"
XP_054727696.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733837.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054728624.1	20	KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6	"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation"
XP_054743118.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054742542.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054736339.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054729556.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054737836.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_054727042.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054741118.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054744860.1	13	Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-216083;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Extracellular matrix organization";"Collagen chain trimerization";"NCAM1 interactions";"ECM proteoglycans";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Anchoring fibril formation";"Integrin cell surface interactions";"Crosslinking of collagen fibrils";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_054733307.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_054734312.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735877.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054743610.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054740056.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_054738437.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542	"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation"
XP_054736173.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054730028.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054732929.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054740620.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054745622.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054731408.1	6	KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622	"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)"
XP_054728879.1	6	Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_054741610.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054739569.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054732679.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-1362409	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis"
XP_054732497.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-1963642;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1251985;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-1236394;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604	"GRB2 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Nuclear signaling by ERBB4";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Signaling by ERBB4";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling"
XP_054734706.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054732641.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_054727914.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5696400	"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER"
XP_054741217.1	5	KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527	"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stachyose degradation"
XP_054747216.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054736940.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054742303.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054738617.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation"
XP_054731445.1	6	KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622	"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)"
XP_054742281.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_054727154.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054735636.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054730567.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054739053.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_054737544.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054743958.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054743493.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151	"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054737677.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054731676.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-6811558	"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_054737499.1	13	Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5678895	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Aggrephagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"HSF1 activation";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Protein methylation";"Ovarian tumor domain proteases";"Defective CFTR causes cystic fibrosis"
XP_054742714.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_054729826.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733062.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation"
XP_054737461.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054740801.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054738121.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_054726099.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054741958.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054730043.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054728098.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_054744236.1	22	Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7592;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7727;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-7606;MetaCyc: PWY-7724	"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_054742592.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"MET activates PTK2 signaling"
XP_054745249.1	10	MetaCyc: PWY-8004;MetaCyc: PWY-1042;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;Reactome: R-HSA-70263;MetaCyc: PWY-6886;Reactome: R-HSA-70171	"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis"
XP_054741327.1	10	KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096	"Galactose metabolism";"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_054738856.1	14	MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-5690;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1	"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation"
XP_054730108.1	9	KEGG: 00270+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5	"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_054730551.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054742334.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport"
XP_054727646.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054745158.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054728280.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054728415.1	19	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-3214858;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"RMTs methylate histone arginines";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_054729508.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_054740652.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_054742215.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_054725534.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054746924.1	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism"
XP_054739579.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_054733456.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054728869.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054742480.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054739541.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054745026.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054735602.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824	"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis"
XP_054741428.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_054739209.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054739915.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054745962.1	2	Reactome: R-HSA-140875;Reactome: R-HSA-202733	"Common Pathway of Fibrin Clot Formation";"Cell surface interactions at the vascular wall"
XP_054735867.1	24	Reactome: R-HSA-165158;Reactome: R-HSA-444257;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-354192;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;KEGG: 04150+2.7.11.1	"Activation of AKT2";"RSK activation";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"Integrin signaling";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Thermogenesis";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"mTOR signaling pathway"
XP_054732090.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_054734511.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054744930.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_054730001.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054742698.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054739534.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_054743607.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054738644.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054729867.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054745051.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054733967.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054726422.1	12	Reactome: R-HSA-2142789;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-1268020	"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import"
XP_054725196.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_054738030.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054738145.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_054741756.1	17	Reactome: R-HSA-9022692;Reactome: R-HSA-9648025;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-174178;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2500257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5663220	"Regulation of MECP2 expression and activity";"EML4 and NUDC in mitotic spindle formation";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Thermogenesis";"Resolution of Sister Chromatid Cohesion";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate Formins"
XP_054730320.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054736364.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_054733310.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054744612.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-9018519	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression"
XP_054742747.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054743756.1	7	KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11	"Methane metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_054735151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054739486.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054738093.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054737531.1	83	Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-5655253;Reactome: R-HSA-1839117;Reactome: R-HSA-6807004;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-9026519;Reactome: R-HSA-5654726;Reactome: R-HSA-2871809;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-186763;Reactome: R-HSA-74749;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-5654704;Reactome: R-HSA-1963642;Reactome: R-HSA-1433559;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-5654699;Reactome: R-HSA-389359;Reactome: R-HSA-2730905;Reactome: R-HSA-8875656;Reactome: R-HSA-1257604;Reactome: R-HSA-5654719;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-8851805;Reactome: R-HSA-391160;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-9027284;Reactome: R-HSA-912631;Reactome: R-HSA-9634285;Reactome: R-HSA-8983432;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-5673001;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-2871796;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-1250347;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5654720;Reactome: R-HSA-8856825;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-180336;Reactome: R-HSA-74751;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-8853659;Reactome: R-HSA-375165;Reactome: R-HSA-8875555;Reactome: R-HSA-1250196;Reactome: R-HSA-2428933;Reactome: R-HSA-512988;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640	"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"Signaling by FGFR2 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"Negative regulation of MET activity";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR1 signaling";"FCERI mediated Ca+2 mobilization";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"Downstream signal transduction";"Signal attenuation";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR3";"PI3K events in ERBB2 signaling";"Regulation of KIT signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"SHC-mediated cascade:FGFR2";"CD28 dependent Vav1 pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"MET receptor recycling";"PIP3 activates AKT signaling";"SHC-mediated cascade:FGFR4";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"MET activates RAS signaling";"Signal regulatory protein family interactions";"MET activates PTPN11";"PI-3K cascade:FGFR1";"Tie2 Signaling";"Spry regulation of FGF signaling";"Erythropoietin activates RAS";"Regulation of signaling by CBL";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin-15 signaling";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"RAF/MAP kinase cascade";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"FCERI mediated MAPK activation";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signalling to RAS";"STAT5 Activation";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PI3K Cascade";"SHC1 events in ERBB4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"PI-3K cascade:FGFR4";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"SHC1 events in EGFR signaling";"Insulin receptor signalling cascade";"FLT3 Signaling";"EGFR downregulation";"RET signaling";"NCAM signaling for neurite out-growth";"MET activates RAP1 and RAC1";"SHC1 events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling"
XP_054744361.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054730338.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054736246.1	10	KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527	"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation"
XP_054741745.1	5	Reactome: R-HSA-205043;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-209560	"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NF-kB is activated and signals survival"
XP_054730808.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054738156.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7102	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_054731083.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054739503.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054730772.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054742605.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054743366.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_054728546.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054730485.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_054747632.1	8	Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_054743183.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway"
XP_054733220.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054741366.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054736754.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054736029.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725981.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)"
XP_054726168.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054739619.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054737237.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054728265.1	20	Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314	"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_054731870.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins"
XP_054746381.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726989.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054739335.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium"
XP_054726400.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_054741451.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054727542.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054729970.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054737968.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054737285.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054742696.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054747052.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054743451.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054735506.1	3	Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2	"Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation"
XP_054745845.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054732142.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054739488.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054730832.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054740937.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054739069.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054745352.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_054733518.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054740350.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-193692	"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR"
XP_054731726.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221	"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway"
XP_054740268.1	6	Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_054740556.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054739214.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_054734428.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054737152.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367	"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines"
XP_054743671.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054738158.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7102	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_054730806.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054743649.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054726827.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054725247.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172	"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions"
XP_054747194.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-5368286;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-5419276;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-5389840;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Mitochondrial translation initiation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Mitochondrial translation termination";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Mitochondrial translation elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_054740545.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054732653.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054734430.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054736248.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054730336.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054747466.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054741467.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054726383.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054729193.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054742709.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_054745631.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054737094.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054729638.1	8	Reactome: R-HSA-373080;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263	"Class B/2 (Secretin family receptors)";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination"
XP_054738650.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054743368.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054728548.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054727840.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982	"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054734493.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_054726571.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054732286.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054729045.1	10	KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864	"Purine metabolism";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"Neutrophil degranulation";"Amyloid fiber formation";"Urate conversion to allantoin III";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events"
XP_054726494.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054744062.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054726685.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054745644.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054746613.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054735193.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054736897.1	10	KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-6174	"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)"
XP_054725324.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_054727963.1	7	MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_054734745.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-189085	"Stimuli-sensing channels";"Digestion of dietary carbohydrate"
XP_054745207.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054725715.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression"
XP_054747218.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054742119.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_054733399.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_054747393.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054729532.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054747800.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054733678.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_054727759.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054742524.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737345.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054731928.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines"
XP_054741585.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054743070.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_054740689.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs"
XP_054729828.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2	"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism"
XP_054743956.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054732019.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054736424.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes"
XP_054732409.1	6	KEGG: 00310+1.2.4.2;Reactome: R-HSA-3371453;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Lysine degradation";"Regulation of HSF1-mediated heat shock response";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_054745156.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054727087.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490	"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins"
XP_054729506.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054747272.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054725091.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054731751.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy"
XP_054736859.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054727035.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054744238.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events"
XP_054738858.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054726243.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_054725823.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054736388.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054734756.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731458.1	6	KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
XP_054738389.1	5	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_054731993.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054735620.1	15	Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519	"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression"
XP_054739633.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054738543.1	2	Reactome: R-HSA-8875656;Reactome: R-HSA-8873719	"MET receptor recycling";"RAB geranylgeranylation"
XP_054744310.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054734795.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744137.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054733371.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054728229.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054731432.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054731777.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_054745567.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_054731371.1	17	Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632	"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis"
XP_054731349.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_054741908.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_054735785.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054726738.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054737395.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_054745043.1	17	Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-8953750;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_054743908.1	12	KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-418594;MetaCyc: PWY-5030;Reactome: R-HSA-6814122;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-5497	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"G alpha (i) signalling events";"L-histidine degradation III";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)"
XP_054727605.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054733668.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054730271.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054729266.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054738530.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054736681.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_054728055.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054738336.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054738806.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054740126.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107	"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_054727698.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054732590.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis"
XP_054739640.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054727133.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735960.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054737407.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054738593.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_054727379.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054737017.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_054729843.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054727341.1	19	Reactome: R-HSA-418885;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-4420097;Reactome: R-HSA-5625970;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-983231	"DCC mediated attractive signaling";"RHO GTPases activate IQGAPs";"EGFR downregulation";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate KTN1";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"Factors involved in megakaryocyte development and platelet production"
XP_054733943.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054727747.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054726007.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054730026.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054732482.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2	"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Cyclin D associated events in G1";"T cell receptor signaling pathway"
XP_054731943.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_054744111.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054736223.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054729652.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054725259.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_054729960.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054733860.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_054744837.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381	"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)"
XP_054747020.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054727804.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742092.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_054727592.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_054747656.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054736919.1	8	MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_054742475.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054726936.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054728523.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport"
XP_054738460.1	6	MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_054735558.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054736575.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054739079.1	8	KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054747283.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054737120.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-416993;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-418597	"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events"
XP_054747476.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_054727833.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308	"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor"
XP_054739553.1	5	MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_054741661.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054730858.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054738261.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054738106.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054743477.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054729472.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054737138.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168	"3-hydroxypropanoate cycle";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Propanoate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)"
XP_054732239.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_054747144.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054745210.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054747645.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054739848.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054732729.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_054726599.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_054726176.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054737044.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054727714.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054742100.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402	"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054730335.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054732152.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054726664.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-174430	"DNA replication initiation";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation"
XP_054744903.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054726597.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054732727.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054744174.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054740546.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054725622.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_054737142.1	7	Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921	"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation"
XP_054745439.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054730387.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_054730805.1	10	Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_054729046.1	10	Reactome: R-HSA-2453902;MetaCyc: PWY-7849;Reactome: R-HSA-975634;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-3000171	"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Retinoid metabolism and transport";"Amyloid fiber formation";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin II";"Neutrophil degranulation";"Non-integrin membrane-ECM interactions"
XP_054741441.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_054738297.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054731813.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054730488.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_054727552.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054729739.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054741697.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054732410.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_054735774.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054736750.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054742608.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_054736931.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054743479.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739528.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054725261.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_054743564.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"mRNA Capping";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_054732237.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_054737286.1	6	MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_054736917.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054746812.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_054742695.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054738034.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Cilium Assembly";"HCMV Early Events";"Recycling pathway of L1";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Aggrephagy"
XP_054729319.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054728266.1	9	KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18	"Drug metabolism - other enzymes";"Glutathione conjugation";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - cytochrome P450"
XP_054728101.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054727907.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_054725460.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_054745263.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054736171.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054744455.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_054732784.1	57	Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084	"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_054740555.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054738148.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054725257.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230	"Tryptophan catabolism";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane"
XP_054743659.1	8	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis"
XP_054744309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054736258.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054728843.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-5633231	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)"
XP_054744839.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054742194.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_054733314.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054738259.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054728284.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054746178.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_054742330.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054742536.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737019.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation"
XP_054727771.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054728960.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
XP_054741403.1	18	MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7115	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_054747524.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054745155.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054742957.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054743946.1	19	Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-432142	"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Chylomicron assembly";"Platelet sensitization by LDL"
XP_054742800.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_054730123.1	7	Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-180746	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein"
XP_054728711.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054725530.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054734755.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054742484.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054739132.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054744941.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054746920.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054742999.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054731448.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054727150.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054728801.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054728472.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_054742961.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054739299.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054738553.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054726686.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054742502.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730633.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_054743955.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054728227.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054743380.1	19	Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-202733;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8963901	"VLDL clearance";"Regulation of TLR by endogenous ligand";"Cell surface interactions at the vascular wall";"Scavenging by Class H Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron remodeling"
XP_054747773.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054745146.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_054727658.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_054742328.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054747535.1	7	MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14	"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism"
XP_054728143.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_054734365.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054736402.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054728095.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054742710.1	182	Reactome: R-HSA-1236974;Reactome: R-HSA-936964;Reactome: R-HSA-5687128;Reactome: R-HSA-9033241;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-8849469;Reactome: R-HSA-5654733;Reactome: R-HSA-6804756;Reactome: R-HSA-168638;Reactome: R-HSA-9637628;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5689877;Reactome: R-HSA-4641258;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-2173788;Reactome: R-HSA-72689;Reactome: R-HSA-8939902;Reactome: R-HSA-182971;Reactome: R-HSA-9615710;Reactome: R-HSA-937072;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-175474;Reactome: R-HSA-450321;Reactome: R-HSA-5654727;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-156902;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-201681;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8875360;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-209543;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-917729;Reactome: R-HSA-5693565;Reactome: R-HSA-1358803;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-2979096;Reactome: R-HSA-5689896;Reactome: R-HSA-5658442;Reactome: R-HSA-5689901;Reactome: R-HSA-8863795;Reactome: R-HSA-5357956;Reactome: R-HSA-2173791;Reactome: R-HSA-975163;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-174490;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-1169408;Reactome: R-HSA-68827;Reactome: R-HSA-5655862;Reactome: R-HSA-8852276;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4641263;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-3769402;Reactome: R-HSA-3134975;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-168928;Reactome: R-HSA-975144;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-5696394;Reactome: R-HSA-975110;Reactome: R-HSA-5684264;Reactome: R-HSA-5696400;Reactome: R-HSA-72706;Reactome: R-HSA-162588;Reactome: R-HSA-69601;Reactome: R-HSA-2559582;Reactome: R-HSA-6781823;Reactome: R-HSA-975957;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-937039;Reactome: R-HSA-174184;Reactome: R-HSA-6804757;Reactome: R-HSA-9020702;Reactome: R-HSA-110312;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9645460;Reactome: R-HSA-174048;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-5656169;Reactome: R-HSA-8866652;Reactome: R-HSA-1799339;Reactome: R-HSA-8951664;Reactome: R-HSA-3322077;Reactome: R-HSA-156827;Reactome: R-HSA-9013973;Reactome: R-HSA-68949;Reactome: R-HSA-937041;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-110314;Reactome: R-HSA-901032;Reactome: R-HSA-8948747;Reactome: R-HSA-5654726;Reactome: R-HSA-937042;Reactome: R-HSA-6783310;Reactome: R-HSA-174113;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-72764;Reactome: R-HSA-8856828;Reactome: R-HSA-168927;Reactome: R-HSA-2672351;Reactome: R-HSA-2559585;Reactome: R-HSA-211733;Reactome: R-HSA-8876493;Reactome: R-HSA-5607761;Reactome: R-HSA-2173796;Reactome: R-HSA-5607764;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-912631;Reactome: R-HSA-209560;Reactome: R-HSA-1234176;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-2691232;Reactome: R-HSA-2559580;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-72702;Reactome: R-HSA-450302;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2122947;Reactome: R-HSA-5696395;Reactome: R-HSA-8948751;Reactome: R-HSA-445989;Reactome: R-HSA-5675221;Reactome: R-HSA-5357905;Reactome: R-HSA-917937;Reactome: R-HSA-72649;Reactome: R-HSA-5358346;Reactome: R-HSA-2122948;Reactome: R-HSA-1236382;Reactome: R-HSA-69541;Reactome: R-HSA-9633012;Reactome: R-HSA-8866654;Reactome: R-HSA-6804760;Reactome: R-HSA-6781827;Reactome: R-HSA-977225;Reactome: R-HSA-69481;Reactome: R-HSA-69231;Reactome: R-HSA-450408;Reactome: R-HSA-2173795;Reactome: R-HSA-6782135;Reactome: R-HSA-2894862;Reactome: R-HSA-192823	"ER-Phagosome pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MAPK6/MAPK4 signaling";"Peroxisomal protein import";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR4 signaling";"Regulation of TP53 Activity through Phosphorylation";"NOD1/2 Signaling Pathway";"Modulation by Mtb of host immune system";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Josephin domain DUBs";"Degradation of DVL";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of TGF-beta receptor signaling";"Formation of a pool of free 40S subunits";"Regulation of RUNX2 expression and activity";"EGFR downregulation";"Late endosomal microautophagy";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"Assembly Of The HIV Virion";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Negative regulation of FGFR2 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Peptide chain elongation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TCF dependent signaling in response to WNT";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"p75NTR recruits signalling complexes";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of ERBB2:ERBB3 signaling";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"Regulation of RAS by GAPs";"Metalloprotease DUBs";"Downregulation of ERBB2 signaling";"TNFR1-induced NFkappaB signaling pathway";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Membrane binding and targetting of GAG proteins";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"ISG15 antiviral mechanism";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLK";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of FZD by ubiquitination";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"Negative regulation of MET activity";"Deactivation of the beta-catenin transactivating complex";"Regulation of innate immune responses to cytosolic DNA";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"DNA Damage Recognition in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dual Incision in GG-NER";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Budding and maturation of HIV virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of TC-NER Pre-Incision Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"IRAK1 recruits IKK complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of TP53 Degradation";"Interleukin-1 signaling";"Translesion synthesis by REV1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Alpha-protein kinase 1 signaling pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Termination of translesion DNA synthesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SRP-dependent cotranslational protein targeting to membrane";"Neddylation";"Glycogen synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"TICAM1-dependent activation of IRF3/IRF7";"Orc1 removal from chromatin";"IKK complex recruitment mediated by RIP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Recognition of DNA damage by PCNA-containing replication complex";"ER Quality Control Compartment (ERQC)";"Regulation of PTEN localization";"Negative regulation of FGFR1 signaling";"IRAK2 mediated activation of TAK1 complex";"Fanconi Anemia Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"Eukaryotic Translation Termination";"Clathrin-mediated endocytosis";"TICAM1, RIP1-mediated IKK complex recruitment";"Stimuli-sensing channels";"Oncogene Induced Senescence";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Dectin-1 mediated noncanonical NF-kB signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"CLEC7A (Dectin-1) signaling";"Aggrephagy";"Selenocysteine synthesis";"Regulation of signaling by CBL";"NF-kB is activated and signals survival";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Oxidative Stress Induced Senescence";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Ribosomal scanning and start codon recognition";"activated TAK1 mediates p38 MAPK activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of Incision Complex in GG-NER";"Regulation of PTEN stability and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of MAPK pathway";"Regulation of TNFR1 signaling";"Iron uptake and transport";"Translation initiation complex formation";"Hedgehog ligand biogenesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Stabilization of p53";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Activity through Methylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Amyloid fiber formation";"G2/M Checkpoints";"Cyclin D associated events in G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual incision in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Viral mRNA Translation"
XP_054726742.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054731347.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054735229.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054737346.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)"
XP_054731741.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054736012.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_054729598.1	4	Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism"
XP_054734254.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054737274.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_054740841.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054734513.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054742131.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054747429.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054732395.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054730003.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054738805.1	10	KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism"
XP_054727761.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054745053.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054729988.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_054732820.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054741996.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-3769402;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"Deactivation of the beta-catenin transactivating complex";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054729265.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741614.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054725858.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054730025.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054735153.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054743614.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054736900.1	10	KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10	"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Butanoate metabolism"
XP_054736857.1	11	Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1660517;KEGG: 04070+2.7.1.137;Reactome: R-HSA-168138	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"PI3K Cascade";"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol signaling system";"Toll Like Receptor 9 (TLR9) Cascade"
XP_054736068.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054736994.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_054727757.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054743539.1	22	MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-7606;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_054733498.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054737533.1	83	Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-9028731;Reactome: R-HSA-2029482;Reactome: R-HSA-1250347;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-5673001;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-2871796;Reactome: R-HSA-9634285;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-8983432;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-1963640;Reactome: R-HSA-9028335;Reactome: R-HSA-182971;Reactome: R-HSA-9607240;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-1250196;Reactome: R-HSA-8856825;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-180336;Reactome: R-HSA-74751;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-5654720;Reactome: R-HSA-5654704;Reactome: R-HSA-1963642;Reactome: R-HSA-1433559;Reactome: R-HSA-8856828;Reactome: R-HSA-5654699;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-5654710;Reactome: R-HSA-6807004;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-5654727;Reactome: R-HSA-9664565;Reactome: R-HSA-5655253;Reactome: R-HSA-1839117;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-9027284;Reactome: R-HSA-912631;Reactome: R-HSA-5654689;Reactome: R-HSA-8865999;Reactome: R-HSA-5654719;Reactome: R-HSA-5655291;Reactome: R-HSA-8875360;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656	"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of actin dynamics for phagocytic cup formation";"SHC1 events in ERBB4 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Signalling to RAS";"STAT5 Activation";"RAF/MAP kinase cascade";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"FCERI mediated MAPK activation";"Constitutive Signaling by Overexpressed ERBB2";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"Interleukin-15 signaling";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"GRB2 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"EGFR downregulation";"FLT3 Signaling";"NCAM signaling for neurite out-growth";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"SHC1 events in ERBB2 signaling";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"SHC1 events in EGFR signaling";"Insulin receptor signalling cascade";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR3";"PI3K events in ERBB2 signaling";"Regulation of KIT signaling";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR2";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"Signal attenuation";"Downstream signal transduction";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"PI-3K cascade:FGFR3";"Negative regulation of MET activity";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"Negative regulation of FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR2 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"Tie2 Signaling";"Spry regulation of FGF signaling";"Erythropoietin activates RAS";"Regulation of signaling by CBL";"PI-3K cascade:FGFR1";"MET activates PTPN11";"SHC-mediated cascade:FGFR4";"Signaling by FGFR4 in disease";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal regulatory protein family interactions";"MET activates RAS signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"PIP3 activates AKT signaling";"MET receptor recycling"
XP_054735642.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054742949.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594	"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events"
XP_054731498.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054732017.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6798695	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Neutrophil degranulation"
XP_054730640.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_054740687.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054732407.1	6	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-3371453;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of HSF1-mediated heat shock response";"Lysine degradation"
XP_054739158.1	10	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-201722	"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Ub-specific processing proteases";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex"
XP_054731081.1	18	MetaCyc: PWY-5532;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.3;MetaCyc: PWY-7179;MetaCyc: PWY-6644;KEGG: 00983+2.4.2.3;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73614;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6608;Reactome: R-HSA-73621	"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Pyrimidine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Pyrimidine catabolism"
XP_054732308.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054738324.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054730259.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054736899.1	10	KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;MetaCyc: PWY-7391	"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_054737396.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054745464.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054747854.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054742117.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_054728638.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054745209.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054733769.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054739962.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054747763.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054736616.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054725983.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I"
XP_054733397.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581	"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation"
XP_054734923.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802	"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3"
XP_054740596.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054741798.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054740390.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_054738105.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054747782.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054747475.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_054725962.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-1989781;Reactome: R-HSA-211945	"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Xenobiotics";"PPARA activates gene expression";"Phase I - Functionalization of compounds"
XP_054731188.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054743798.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054725249.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054742656.1	3	Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144	"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_054738604.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054726829.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054743647.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054732628.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054727520.1	5	Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471	"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_054741491.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_054743204.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_054747646.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054738123.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054741574.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054727538.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054747655.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054740939.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054730553.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054745503.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054737054.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054736370.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I"
XP_054743233.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054742144.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054732138.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054742817.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054747154.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054741233.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054738633.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054726935.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054738198.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_054740919.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054732610.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054742408.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054743679.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054747164.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_054725277.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054743641.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054727726.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054728794.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_054740575.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054736151.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054747665.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054727236.1	29	Reactome: R-HSA-6803207;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69473;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-6804757;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6803204;KEGG: 05165+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G2/M DNA damage checkpoint";"Relaxin signaling pathway";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Degradation";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human papillomavirus infection";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends"
XP_054727870.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054744092.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054726579.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle"
XP_054743398.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054726541.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_054731542.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054742837.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054737064.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054746983.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054735182.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_054738613.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"Dual incision in TC-NER";"mRNA Capping";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_054742307.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054742701.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744655.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_054729882.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054728027.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054736167.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054735863.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054740704.1	7	KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-6724	"Starch and sucrose metabolism";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Neutrophil degranulation";"Starch degradation II"
XP_054741835.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054734729.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054731840.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054726981.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054736212.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054735754.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054732443.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054726053.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054737329.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054735246.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054728700.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054741323.1	10	KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096	"Galactose metabolism";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_054744154.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_054736595.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_054739061.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054730291.1	14	MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054731759.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054741975.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054743519.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054732085.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_054746470.1	17	MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-6545	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_054742252.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054741625.1	24	Reactome: R-HSA-163358;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-9634600;Reactome: R-HSA-164378;Reactome: R-HSA-8963896;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-392517;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-5621575;Reactome: R-HSA-422356;Reactome: R-HSA-163560;Reactome: R-HSA-5610780	"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA activation in glucagon signalling";"HDL assembly";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Rap1 signalling";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"RET signaling";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"CD209 (DC-SIGN) signaling";"Regulation of insulin secretion";"Triglyceride catabolism";"Degradation of GLI1 by the proteasome"
XP_054733024.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054730404.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054727678.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Intraflagellar transport"
XP_054744997.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054726503.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054747242.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054737609.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054733963.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054729863.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II"
XP_054735882.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054742137.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_054741603.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727170.1	8	Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054726525.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_054726619.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670	"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis"
XP_054739168.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_054747363.1	4	Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219	"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_054733369.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054742111.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054727612.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054726534.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054731369.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054738315.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054739422.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins"
XP_054735386.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731391.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_054736058.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054729182.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054743187.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054731648.1	22	Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Degradation of beta-catenin by the destruction complex";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation"
XP_054730490.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054739507.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_054727930.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
XP_054731087.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054732401.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054727751.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054737375.1	7	KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.17	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis"
XP_054731035.1	9	Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9608287;Reactome: R-HSA-9630222;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-9608290	"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate binding";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Defective MUTYH substrate processing"
XP_054742627.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054743634.1	5	MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
XP_054735492.1	13	KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation"
XP_054746501.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_054741414.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054732183.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_054734842.1	4	Reactome: R-HSA-8953750;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_054744947.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054725736.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054734980.1	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054739670.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054735719.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054732366.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_054746918.1	5	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_054741288.1	5	Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
XP_054726263.1	3	KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_054738688.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736689.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054738047.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_054741965.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054728717.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054739178.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_054727160.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054747515.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054747629.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054731973.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054732745.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733973.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054727777.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883	"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II"
XP_054738180.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_054729873.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054727371.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_054725226.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054733104.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736877.1	9	MetaCyc: PWY-7442;MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-6147	"Drosopterin and aurodrosopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"
XP_054741780.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054737746.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054735173.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054731341.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_054727016.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476	"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events"
XP_054739450.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054725878.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727943.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_054736416.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_054747373.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054731190.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054728221.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_054733379.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054733698.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_054743090.1	3	MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3	"Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism"
XP_054744773.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054735442.1	4	MetaCyc: PWY-7927;MetaCyc: PWY-5350;KEGG: 00920+2.8.1.1;Reactome: R-HSA-1614558	"Sulfide oxidation IV (mitochondria)";"Thiosulfate disproportionation IV (rhodanese)";"Sulfur metabolism";"Degradation of cysteine and homocysteine"
XP_054747139.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054732244.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_054728731.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559	"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway"
XP_054737365.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054740435.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054745073.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730440.1	6	KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_054728385.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_054728950.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054735339.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-4702;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25	"Myo-inositol biosynthesis";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system"
XP_054732607.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_054731133.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_054732862.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_054742967.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054730225.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054740565.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054738014.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054739702.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054733215.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054729809.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054725267.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_054737663.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_054731480.1	14	Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_054741447.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_054747446.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054732883.1	3	MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9	"Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis"
XP_054730097.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054726146.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054737074.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054747925.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054741348.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054744819.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054730573.1	18	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism"
XP_054731804.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054727860.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054728256.1	11	Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1	"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"p38MAPK events";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection"
XP_054726474.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054725450.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054726591.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054731592.1	22	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_054732721.1	6	Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_054730315.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054732958.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_054733714.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054728245.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054735873.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054733890.1	13	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants"
XP_054725251.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054731833.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054733281.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054747309.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_054733303.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054740248.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054742445.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054725490.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054743712.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_054741306.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-73776	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"HIV Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape"
XP_054747837.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054738670.1	9	Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664	"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Neddylation"
XP_054743500.1	5	Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation"
XP_054733552.1	7	Reactome: R-HSA-2160456;MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1	"Phenylketonuria";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis"
XP_054737118.1	8	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_054732905.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054730057.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054728873.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054726600.1	5	KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_054742164.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054734120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054737610.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_054745007.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054747018.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054727734.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054732923.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2644606	"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054743651.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054745431.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_054727725.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054740370.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356	"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_054729438.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054735568.1	7	MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Sesamin biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_054745372.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054744817.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054744144.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation"
XP_054741332.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054738112.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054737443.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_054743667.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054742886.1	8	MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5740;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;Reactome: R-HSA-6787639	"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis"
XP_054725269.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_054743802.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054727703.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054741594.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054726043.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054741449.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054732453.1	8	Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription"
XP_054743332.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"2-LTR circle formation"
XP_054729337.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054734630.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054735744.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054727235.1	29	Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;Reactome: R-HSA-6796648;Reactome: R-HSA-6804757;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803204;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1	"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Degradation";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Human papillomavirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Relaxin signaling pathway"
XP_054747666.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054736103.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054737818.1	3	Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events"
XP_054739291.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148	"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG"
XP_054741136.1	7	Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_054740489.1	3	KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117;MetaCyc: PWY-0	"Arginine and proline metabolism";"Spermine and spermidine degradation I";"Putrescine degradation III"
XP_054731478.1	14	Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507	"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054744589.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054738702.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054739014.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_054726808.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054727113.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054738878.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054735221.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054737376.1	13	Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-5607764	"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling"
XP_054731036.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054737200.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054747252.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_054732513.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_054733377.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054726437.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054745176.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054737294.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054739582.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Synthesis of PE";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_054744844.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562	"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)"
XP_054740861.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054739433.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054725563.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054731658.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054747627.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054741626.1	24	Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-5610780;Reactome: R-HSA-163560;Reactome: R-HSA-381676;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-392517;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-5687128;Reactome: R-HSA-8963896;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-9634600;Reactome: R-HSA-164378;Reactome: R-HSA-163358;Reactome: R-HSA-9010642	"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"RET signaling";"mTOR signaling pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Rap1 signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"MAPK6/MAPK4 signaling";"HDL assembly";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA activation in glucagon signalling";"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5"
XP_054737401.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054732086.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211	"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling"
XP_054734522.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054737011.1	10	KEGG: 00562+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00051+5.3.1.1	"Inositol phosphate metabolism";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Fructose and mannose metabolism"
XP_054727741.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054733658.1	15	KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-2221	"Purine metabolism";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_054727779.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054741976.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054734308.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726526.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054728933.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054744949.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054734017.1	10	KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6535;Reactome: R-HSA-916853	"Propanoate metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"4-aminobutanoate degradation III";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation I";"Degradation of GABA"
XP_054733150.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054726718.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054738049.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054738736.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054736687.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054730670.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054729794.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054736415.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054736280.1	8	KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;MetaCyc: PWY-6611;Reactome: R-HSA-5683826	"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Surfactant metabolism"
XP_054735922.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054728492.1	13	Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6804757	"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of TP53 Degradation"
XP_054737745.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054727015.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054730920.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054739279.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054733910.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599	"Biotin metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_054725315.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054745166.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054734852.1	3	Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_054744957.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Dual incision in TC-NER"
XP_054745383.1	16	Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398	"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway"
XP_054729208.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054739992.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054737366.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_054744536.1	7	Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO"
XP_054742292.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6	"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism"
XP_054747220.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054743189.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054731799.1	3	KEGG: 00540+2.7.7.38;Reactome: R-HSA-4085001;MetaCyc: PWY-1269	"Lipopolysaccharide biosynthesis";"Sialic acid metabolism";"CMP-3-deoxy-D-manno-octulosonate biosynthesis"
XP_054736891.1	23	Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418217	"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta"
XP_054737183.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_054737560.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054745400.1	7	MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_054727769.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603	"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases"
XP_054741966.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054735618.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054725381.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744272.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054725787.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054725735.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054725573.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054742139.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_054728940.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_054729512.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_054742373.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054725225.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054737756.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731122.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054732746.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054727498.1	10	Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903	"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy"
XP_054727953.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation"
XP_054741517.1	4	Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2	"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_054740944.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054733122.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_054747310.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_054727081.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054740750.1	10	Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300	"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors"
XP_054737721.1	7	KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-163210	"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Cristae formation";"Mitochondrial protein import";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling"
XP_054737327.1	16	Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-5603037;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-6811558	"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_054729110.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054735512.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054741260.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_054738952.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054731520.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_054743984.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054744608.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054727680.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Intraflagellar transport"
XP_054743358.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054732588.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054743260.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_054734000.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_054728029.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054738168.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7102	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)"
XP_054739381.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_054745611.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_054739787.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_054729452.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054729618.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054736169.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054746781.1	7	Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2	"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Cristae formation";"Oxidative phosphorylation"
XP_054742174.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054746387.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054737231.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736340.1	6	Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-73930;Reactome: R-HSA-110373	"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway"
XP_054730878.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054737428.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054728863.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054744100.1	179	Reactome: R-HSA-2672351;Reactome: R-HSA-2559585;Reactome: R-HSA-211733;Reactome: R-HSA-8876493;Reactome: R-HSA-5607761;Reactome: R-HSA-2173796;Reactome: R-HSA-5607764;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-912631;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-110314;Reactome: R-HSA-901032;Reactome: R-HSA-8948747;Reactome: R-HSA-5654726;Reactome: R-HSA-937042;Reactome: R-HSA-6783310;Reactome: R-HSA-174113;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-72764;Reactome: R-HSA-8856828;Reactome: R-HSA-168927;Reactome: R-HSA-9645460;Reactome: R-HSA-174048;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-5656169;Reactome: R-HSA-8866652;Reactome: R-HSA-1799339;Reactome: R-HSA-8951664;Reactome: R-HSA-9013973;Reactome: R-HSA-3322077;Reactome: R-HSA-156827;Reactome: R-HSA-68949;Reactome: R-HSA-937041;Reactome: R-HSA-8854050;Reactome: R-HSA-975957;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-937039;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-6804757;Reactome: R-HSA-110312;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-6804760;Reactome: R-HSA-6781827;Reactome: R-HSA-977225;Reactome: R-HSA-69481;Reactome: R-HSA-69231;Reactome: R-HSA-450408;Reactome: R-HSA-6782135;Reactome: R-HSA-2173795;Reactome: R-HSA-2894862;Reactome: R-HSA-192823;Reactome: R-HSA-8948751;Reactome: R-HSA-445989;Reactome: R-HSA-5675221;Reactome: R-HSA-5357905;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-2122948;Reactome: R-HSA-69541;Reactome: R-HSA-1236382;Reactome: R-HSA-9633012;Reactome: R-HSA-8866654;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-450302;Reactome: R-HSA-180585;Reactome: R-HSA-2122947;Reactome: R-HSA-5696395;Reactome: R-HSA-1234176;Reactome: R-HSA-209560;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-2559580;Reactome: R-HSA-2691232;Reactome: R-HSA-5362768;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8875360;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-209543;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-4641257;Reactome: R-HSA-5654727;Reactome: R-HSA-8941858;Reactome: R-HSA-156902;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-201681;Reactome: R-HSA-5689877;Reactome: R-HSA-4641258;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-2173788;Reactome: R-HSA-72689;Reactome: R-HSA-8939902;Reactome: R-HSA-182971;Reactome: R-HSA-9615710;Reactome: R-HSA-937072;Reactome: R-HSA-5676590;Reactome: R-HSA-5205685;Reactome: R-HSA-175474;Reactome: R-HSA-450321;Reactome: R-HSA-1236974;Reactome: R-HSA-936964;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9033241;Reactome: R-HSA-5678895;Reactome: R-HSA-8849469;Reactome: R-HSA-6804756;Reactome: R-HSA-5654733;Reactome: R-HSA-168638;Reactome: R-HSA-9637628;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5684264;Reactome: R-HSA-5696400;Reactome: R-HSA-72706;Reactome: R-HSA-162588;Reactome: R-HSA-69601;Reactome: R-HSA-2559582;Reactome: R-HSA-6781823;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-4641263;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-3769402;Reactome: R-HSA-3134975;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-168928;Reactome: R-HSA-975144;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-975110;Reactome: R-HSA-5696394;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-174490;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-1169408;Reactome: R-HSA-68827;Reactome: R-HSA-5655862;Reactome: R-HSA-8852276;Reactome: R-HSA-917729;Reactome: R-HSA-5693565;Reactome: R-HSA-1358803;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-5689896;Reactome: R-HSA-2979096;Reactome: R-HSA-5658442;Reactome: R-HSA-5689901;Reactome: R-HSA-8863795;Reactome: R-HSA-2173791;Reactome: R-HSA-5357956;Reactome: R-HSA-975163	"Stimuli-sensing channels";"Oncogene Induced Senescence";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"InlA-mediated entry of Listeria monocytogenes into host cells";"Dectin-1 mediated noncanonical NF-kB signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"CLEC7A (Dectin-1) signaling";"Aggrephagy";"Selenocysteine synthesis";"Regulation of signaling by CBL";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Recognition of DNA damage by PCNA-containing replication complex";"ER Quality Control Compartment (ERQC)";"Regulation of PTEN localization";"Negative regulation of FGFR1 signaling";"IRAK2 mediated activation of TAK1 complex";"Fanconi Anemia Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"Eukaryotic Translation Termination";"Clathrin-mediated endocytosis";"TICAM1, RIP1-mediated IKK complex recruitment";"Alpha-protein kinase 1 signaling pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Termination of translesion DNA synthesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"SRP-dependent cotranslational protein targeting to membrane";"Neddylation";"TICAM1-dependent activation of IRF3/IRF7";"Glycogen synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Orc1 removal from chromatin";"IKK complex recruitment mediated by RIP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"IRAK1 recruits IKK complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Regulation of TP53 Degradation";"Translesion synthesis by REV1";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of TP53 Activity through Methylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Amyloid fiber formation";"G2/M Checkpoints";"Cyclin D associated events in G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dual incision in TC-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Viral mRNA Translation";"Regulation of PTEN stability and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulation of MAPK pathway";"Regulation of TNFR1 signaling";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Stabilization of p53";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"E3 ubiquitin ligases ubiquitinate target proteins";"FCERI mediated NF-kB activation";"UCH proteinases";"activated TAK1 mediates p38 MAPK activation";"Vif-mediated degradation of APOBEC3G";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of Incision Complex in GG-NER";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NF-kB is activated and signals survival";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Oxidative Stress Induced Senescence";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"p75NTR recruits signalling complexes";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"Degradation of AXIN";"Negative regulation of FGFR2 signaling";"Regulation of RUNX3 expression and activity";"Peptide chain elongation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TCF dependent signaling in response to WNT";"Josephin domain DUBs";"Degradation of DVL";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of TGF-beta receptor signaling";"Formation of a pool of free 40S subunits";"Regulation of RUNX2 expression and activity";"EGFR downregulation";"Late endosomal microautophagy";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NIK-->noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"Assembly Of The HIV Virion";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"ER-Phagosome pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Peroxisomal protein import";"Defective CFTR causes cystic fibrosis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR4 signaling";"NOD1/2 Signaling Pathway";"Modulation by Mtb of host immune system";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dual Incision in GG-NER";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Budding and maturation of HIV virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of TC-NER Pre-Incision Complex";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of FZD by ubiquitination";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"Negative regulation of MET activity";"Deactivation of the beta-catenin transactivating complex";"Regulation of innate immune responses to cytosolic DNA";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DNA Damage Recognition in GG-NER";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Membrane binding and targetting of GAG proteins";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"ISG15 antiviral mechanism";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLK";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of ERBB2:ERBB3 signaling";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"Ovarian tumor domain proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of RAS by GAPs";"Metalloprotease DUBs";"Downregulation of ERBB2 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation"
XP_054739573.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054736986.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054745685.1	7	KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_054747445.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054739724.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054739059.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054741768.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054737430.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054730226.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_054726093.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054728255.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054730812.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_054747926.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054733538.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054728364.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054725279.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054743544.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_054734211.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054743677.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-2467813	"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Separation of Sister Chromatids"
XP_054747062.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_054726145.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054736320.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054734747.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745080.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054734379.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054745205.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727708.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054726635.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054726687.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_054734190.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054728812.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054739107.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054736895.1	10	KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;MetaCyc: PWY-7524;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;MetaCyc: PWY-7391	"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)"
XP_054736411.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_054732357.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054745147.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054735563.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741773.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054733540.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054727872.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054747380.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_054742511.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054731346.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054730182.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054732930.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_054739245.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054741587.1	18	MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1	"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_054727376.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054727037.1	13	MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-9027277;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433	"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Generation of second messenger molecules"
XP_054736210.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054731842.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054742537.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054740514.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054736485.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_054742956.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054731264.1	4	KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism"
XP_054734605.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054732928.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054729880.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054733409.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054730029.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_054741119.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054732170.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054726974.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054725385.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054725662.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054727795.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054736338.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054740875.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054732361.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054726624.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054747425.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054743709.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054745615.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA"
XP_054744554.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_054736916.1	8	MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7198;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_054737287.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054732572.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054726939.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054747240.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054735291.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_054725744.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054746801.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_054727906.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054728267.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054746472.1	4	Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Glycerolipid metabolism";"Glycerol degradation I";"Pentose and glucuronate interconversions"
XP_054728450.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054737314.1	14	Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944	"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2"
XP_054742649.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054726834.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054727172.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054734281.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-5723	"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Rubisco shunt"
XP_054726304.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism"
XP_054736567.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054740935.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054743914.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054726596.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054738873.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054726390.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054741465.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_054734909.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-5683826	"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Surfactant metabolism"
XP_054732518.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054726825.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054725245.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214	"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs"
XP_054730386.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_054727610.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054740674.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054740547.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054737224.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054741696.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054747479.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_054740175.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054743042.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_054747441.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_054729047.1	7	MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-5695;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis"
XP_054732236.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_054727118.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054741819.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_054744835.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_054727384.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054747723.1	6	KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-8004	"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I"
XP_054746130.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054730933.1	5	Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"Gap junction degradation";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_054740559.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054738364.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727493.1	10	Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695	"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation"
XP_054736644.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054735613.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054738182.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054736030.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054727162.1	12	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1632852	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy"
XP_054736783.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054733239.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054747233.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_054730173.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054736028.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054729203.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054745388.1	19	Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport"
XP_054739618.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_054726169.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827	"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_054746056.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
XP_054727883.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054731192.1	13	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;Reactome: R-HSA-3928663;Reactome: R-HSA-416482	"PI3K-Akt signaling pathway";"Thermogenesis";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events"
XP_054744641.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054740597.1	7	Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054737188.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054738863.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054727231.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054733192.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_054728952.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054747204.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054741092.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054727721.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054730809.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_054743646.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054742657.1	7	MetaCyc: PWY-5265;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356	"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2"
XP_054740165.1	6	Reactome: R-HSA-2151201;Reactome: R-HSA-8862803;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-3299685	"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Detoxification of Reactive Oxygen Species"
XP_054747647.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054728099.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054726098.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054727756.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054741959.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054739512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054735225.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054728061.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054737081.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054746276.1	7	MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_054732406.1	6	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-3371453;KEGG: 00310+1.2.4.2	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of HSF1-mediated heat shock response";"Lysine degradation"
XP_054732016.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"Neutrophil degranulation"
XP_054737953.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_054737397.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054734087.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054745740.1	6	KEGG: 00562+3.1.3.56;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6362;MetaCyc: PWY-6364	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_054727607.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054727862.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054725452.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-1236978	"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_054733396.1	10	KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_054746893.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_054740253.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054736617.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054741763.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054738386.1	9	Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-8004;KEGG: 00710+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_054743997.1	10	Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111459	"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage"
XP_054741429.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_054729613.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_054739208.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054735724.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054738163.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-6383	"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_054734024.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054727560.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054737423.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_054740009.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054726891.1	3	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_054741997.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257;Reactome: R-HSA-168333	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_054739578.1	14	Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7782	"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Plasmalogen biosynthesis"
XP_054739084.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054731504.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054729509.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054745159.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054726415.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_054741353.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054740865.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054739810.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054737405.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054737359.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054734963.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_054727745.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054745248.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054735234.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054741710.1	16	Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_054738672.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_054732779.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054742955.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054747511.1	14	KEGG: 00564+2.3.1.42;MetaCyc: PWY-8055;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PA";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis"
XP_054743328.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054745157.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054746764.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054725492.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054743710.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054741328.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_054727375.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054737357.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054741427.1	8	Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168	"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_054735868.1	24	KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-444257;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Integrin signaling";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"RSK activation";"Activation of AKT2";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"PI3K-Akt signaling pathway"
XP_054745232.1	6	Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700	"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling"
XP_054736392.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054741961.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054725580.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054744517.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054731601.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_054725163.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054726602.1	5	Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3	"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_054730568.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054736896.1	10	MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway I";"Butanoate metabolism";"PPARA activates gene expression";"Terpenoid backbone biosynthesis"
XP_054734089.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_054735789.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054737361.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054740431.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054744531.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054727609.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054739029.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054728381.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_054741218.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation"
XP_054745206.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054743330.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054728097.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_054744189.1	13	Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"NCAM1 interactions";"Collagen chain trimerization";"Extracellular matrix organization";"Signaling by PDGF";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Collagen degradation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_054742403.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054730683.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054741957.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054741800.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_054741330.1	10	KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_054747537.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054743800.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_054737678.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_054743957.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054725246.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_054742659.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054730950.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_054731643.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054740902.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054726826.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054730807.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054729061.1	14	MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5076;MetaCyc: PWY-5103;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5057;Reactome: R-HSA-70895;KEGG: 00280+2.6.1.42	"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"Glucosinolate biosynthesis";"L-valine degradation II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_054735952.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054741466.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054730337.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054730076.1	11	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-2173796;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling"
XP_054733643.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054725863.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054737202.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054726167.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054731094.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_054739940.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054732235.1	4	Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_054734538.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054733211.1	3	Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096	"CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation"
XP_054741695.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054736981.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054738084.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054734520.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054733000.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_054743608.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054744358.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_054727905.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054733410.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054745899.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade"
XP_054733968.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054737236.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054739580.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis"
XP_054742441.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054742697.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742479.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054744984.1	4	KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_054728613.1	5	KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_054731410.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation"
XP_054741608.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054742748.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054728279.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism"
XP_054725364.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054737518.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054726151.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054740557.1	22	MetaCyc: PWY-5384;MetaCyc: PWY-5054;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-6992;MetaCyc: PWY-5659;KEGG: 00030+5.3.1.9;MetaCyc: PWY-621;KEGG: 00010+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-8013;Reactome: R-HSA-70171;MetaCyc: PWY-6981;Reactome: R-HSA-5628897;MetaCyc: PWY-7238;MetaCyc: PWY-3801;MetaCyc: PWY-622;KEGG: 00520+5.3.1.9	"Sucrose degradation IV (sucrose phosphorylase)";"D-sorbitol biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"1,5-anhydrofructose degradation";"GDP-mannose biosynthesis";"Pentose phosphate pathway";"Sucrose degradation III (sucrose invertase)";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"Chitin biosynthesis";"TP53 Regulates Metabolic Genes";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Starch biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054737726.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731321.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379	"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres"
XP_054739492.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054738107.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054729812.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_054736654.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054747699.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis"
XP_054747477.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_054730672.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054742881.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054743476.1	19	KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_054739933.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_054742290.1	58	MetaCyc: PWY-7778;Reactome: R-HSA-77288;MetaCyc: PWY-5789;MetaCyc: PWY-6883;Reactome: R-HSA-77310;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;MetaCyc: PWY-7726;MetaCyc: PWY-6946;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7401;MetaCyc: PWY-5138;Reactome: R-HSA-77305;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00362+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00720+4.2.1.17;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-6583;KEGG: 00281+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-1361;MetaCyc: PWY-7656;KEGG: 00650+4.2.1.17;KEGG: 00310+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7779;Reactome: R-HSA-77348;MetaCyc: PWY-7654;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;Reactome: R-HSA-77285;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6863;MetaCyc: PWY-5136	"2-methylpropene degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Limonene and pinene degradation";"Caprolactam degradation";"Acyl chain remodeling of CL";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Tryptophan metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Androstenedione degradation";"Lysine degradation";"Valine, leucine and isoleucine degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Toluene degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Benzoate degradation";"Butanoate metabolism";"Glutaryl-coa degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid elongation";"Phenylalanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Benzoate degradation";"beta-Alanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Carbon fixation pathways in prokaryotes";"Geraniol degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"Geraniol degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Butanoate metabolism";"Lysine degradation";"Propanoate metabolism";"Methyl tert-butyl ether degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Aminobenzoate degradation";"Fatty acid salvage";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"Fatty acid elongation";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_054738245.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054740383.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054747222.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054735251.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_054739990.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-2644606	"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054744594.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054725873.1	12	MetaCyc: PWY-1861;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)"
XP_054732680.1	3	MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51	"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation"
XP_054742491.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054740010.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054728880.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling"
XP_054730618.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054730452.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054743020.1	8	Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Ion channel transport";"Photosynthesis";"Insulin receptor recycling"
XP_054729878.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054738568.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054745402.1	7	MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7841	"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis"
XP_054735450.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"UCH proteinases";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_054744270.1	26	Reactome: R-HSA-4615885;Reactome: R-HSA-110314;Reactome: R-HSA-1362277;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-174417;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135	"SUMOylation of DNA replication proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Telomere C-strand (Lagging Strand) Synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual incision in TC-NER"
XP_054739065.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054744836.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_054729702.1	26	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-1912408	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"Attenuation phase";"SUMOylation of transcription cofactors";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Pre-NOTCH Transcription and Translation"
XP_054739809.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_054744651.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054740884.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_054726937.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054739442.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-1236974;Reactome: R-HSA-975138;Reactome: R-HSA-6811558;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-975110;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702	"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"ER-Phagosome pathway";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling"
XP_054733120.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_054746046.1	4	Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546	"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin";"Prolactin receptor signaling"
XP_054728269.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842	"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II"
XP_054741301.1	9	Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-70263	"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis"
XP_054729510.1	6	MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054741283.1	27	Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159231	"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_054742798.1	14	MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;Reactome: R-HSA-1483166	"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA"
XP_054738683.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054727365.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054738337.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054738076.1	56	Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs"
XP_054733308.1	4	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054727682.1	4	MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_054729267.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054743262.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054744976.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_054740752.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022692;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-427413	"MECP2 regulates transcription of neuronal ligands";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"Regulation of MECP2 expression and activity";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression"
XP_054743117.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054725339.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054740243.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054732397.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054733838.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054741262.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_054743844.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054741949.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727746.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054732498.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054736342.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054743621.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_054737016.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_054741971.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054727039.1	40	Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167238	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054737406.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054740611.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054732081.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054746598.1	7	Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;KEGG: 00195+7.1.2.2	"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Photosynthesis"
XP_054741621.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136	"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_054730027.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054733407.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054732015.1	7	Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753	"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions"
XP_054740362.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689	"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex"
XP_054732405.1	6	KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-3371453;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of HSF1-mediated heat shock response";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_054738420.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_054725990.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054731031.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054727755.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054737371.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_054741589.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735812.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745917.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_054729670.1	7	Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351	"Synthesis of PI";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_054743131.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-9013700	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_054742115.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_054735071.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054731820.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054734749.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054742996.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_054729920.1	4	Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511	"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination"
XP_054738311.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054733820.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054732888.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_054738717.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054736263.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054730810.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_054746523.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054741627.1	24	Reactome: R-HSA-164378;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-9634600;Reactome: R-HSA-163358;Reactome: R-HSA-9010642;Reactome: R-HSA-8963896;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-392517;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-432040;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-5610780;Reactome: R-HSA-163560	"PKA activation in glucagon signalling";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5";"HDL assembly";"PKA activation";"VEGFA-VEGFR2 Pathway";"Rap1 signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"RET signaling";"mTOR signaling pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism"
XP_054729972.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054733401.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_054730021.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054737002.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739598.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054741977.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054731872.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_054736742.1	10	KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11	"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Fructose and mannose metabolism"
XP_054726012.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054727540.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054733294.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-532668;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880	"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases"
XP_054738095.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054743111.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A"
XP_054742135.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054725739.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054740845.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054734406.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054740121.1	9	Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004	"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I"
XP_054738801.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_054732391.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054726527.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054733708.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_054728553.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054736686.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis"
XP_054745556.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054745350.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054732140.1	4	KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_054747136.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_054741137.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054736865.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054738317.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054734160.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054730483.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway"
XP_054731818.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054735806.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735077.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism"
XP_054742124.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_054740856.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_054733818.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_054739523.1	10	MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6554;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054731037.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054737377.1	13	Reactome: R-HSA-937072;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9014325	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex"
XP_054727980.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054737749.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054727842.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308	"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Long-term potentiation";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor"
XP_054743743.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727409.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054738284.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054741743.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054745177.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054738008.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054740762.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054746873.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054726436.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054733376.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054731085.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054736009.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_054733570.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054739505.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_054735593.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054738960.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054738418.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68827	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex"
XP_054743684.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_054727653.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_054730193.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054744661.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054740644.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054726149.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054744699.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985	"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose"
XP_054728259.1	11	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"p38MAPK events";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_054730045.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054744816.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_054726258.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_054745032.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054733906.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-73779	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054732982.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054742887.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054731443.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054734562.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054747667.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054738101.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy"
XP_054737850.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054747802.1	14	MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054739055.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054743072.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_054747594.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_054739319.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054743811.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054741701.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054746809.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_054726750.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054747500.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Photosynthesis";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Ion channel transport";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054743307.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054743701.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054744657.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_054728025.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054731118.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_054729528.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054736165.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054739913.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054732542.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054730620.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054747651.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054736664.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_054741018.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054728413.1	5	Reactome: R-HSA-4793954;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;Reactome: R-HSA-532668	"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054741445.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054730095.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054732303.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054744921.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_054733430.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_054736987.1	5	MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054746882.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054731217.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_054725354.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054738893.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054730227.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-3108214;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-5693616	"Dual incision in TC-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"HSF1 activation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Meiotic recombination";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054726161.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054728198.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054725265.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054734202.1	3	KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_054732714.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors"
XP_054735470.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054733958.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054741676.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054737538.1	83	Reactome: R-HSA-912631;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-5654719;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-5654699;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-8856828;Reactome: R-HSA-5654704;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-9026519;Reactome: R-HSA-6807004;Reactome: R-HSA-1839117;Reactome: R-HSA-5655253;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640;Reactome: R-HSA-512988;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-1250196;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-5655302;Reactome: R-HSA-5654712;Reactome: R-HSA-8856825;Reactome: R-HSA-5654720;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-1250347;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-8851907;Reactome: R-HSA-5654733;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-983695;Reactome: R-HSA-8853334;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-2871796;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-8853338;Reactome: R-HSA-5654732;Reactome: R-HSA-2424491;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285	"Regulation of signaling by CBL";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling";"MET activates PTPN11";"PI-3K cascade:FGFR1";"Signal regulatory protein family interactions";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"SHC-mediated cascade:FGFR4";"PIP3 activates AKT signaling";"MET receptor recycling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"SHC-mediated cascade:FGFR2";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Signal attenuation";"Downstream signal transduction";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"Activated NTRK2 signals through RAS";"Negative regulation of MET activity";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR2 in disease";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"SHC1 events in ERBB2 signaling";"NCAM signaling for neurite out-growth";"RET signaling";"FLT3 Signaling";"EGFR downregulation";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"Signaling by FGFR1 in disease";"FRS-mediated FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR4";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"SHC1 events in ERBB4 signaling";"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"MET activates PI3K/AKT signaling";"Negative regulation of FGFR4 signaling";"Signalling to RAS";"STAT5 Activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"FCERI mediated MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR3 signaling";"DAP12 signaling";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2"
XP_054747499.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733384.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_054730472.1	14	MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;MetaCyc: PWY-3841;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1	"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"One carbon pool by folate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Folate transformations I";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism"
XP_054740043.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054731493.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054737822.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_054727729.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054727054.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_054744451.1	8	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_054735271.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054735249.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054737326.1	16	Reactome: R-HSA-975138;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-209543	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes"
XP_054736829.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054739642.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054730317.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735501.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054733327.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054746492.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054742669.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054740600.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-110320	"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Translesion Synthesis by POLH"
XP_054730652.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054734518.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054736547.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054744758.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054725786.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054726899.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054734930.1	2	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation"
XP_054741967.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054742090.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_054728715.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_054743238.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054738045.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_054738193.1	6	KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_054735983.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054741421.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054731244.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054744945.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054738638.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054743310.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_054729271.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054737122.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis"
XP_054727533.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054727775.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054743516.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054726994.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054732190.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054738130.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054740718.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054741310.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054738462.1	10	Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Lipophagy";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs"
XP_054732379.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_054729470.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054740338.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I"
XP_054735858.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054734361.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_054736875.1	9	MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-6983;MetaCyc: PWY-7852;MetaCyc: PWY-7442	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Drosopterin and aurodrosopterin biosynthesis"
XP_054728488.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054726857.1	6	Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_054731745.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_054725153.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054738128.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054741793.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054728387.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167242	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_054744585.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054740772.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054734928.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054742965.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054735543.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054745167.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"Neddylation";"UCH proteinases";"TGF-beta receptor signaling activates SMADs"
XP_054742414.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054738056.1	18	Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Acyl chain remodelling of PI";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
XP_054744537.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346	"Hedgehog 'on' state";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis"
XP_054737367.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_054740437.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054737140.1	7	KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500	"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle"
XP_054728389.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054729633.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054729198.1	7	MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46	"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Canavanine degradation";"Urea cycle";"Urea cycle";"Arginine and proline metabolism";"Putrescine biosynthesis III"
XP_054735335.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3	"Fructose catabolism";"Essential fructosuria";"Fructose and mannose metabolism"
XP_054741363.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054737391.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054735387.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054746027.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054737369.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_054743363.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054747135.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013	"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_054734498.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_054735091.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054731086.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054739506.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054725128.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054738153.1	13	MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-5122	"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis"
XP_054739300.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054735069.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054737648.1	13	MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I"
XP_054747634.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054728858.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054727550.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054736243.1	10	MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-6317;Reactome: R-HSA-70370	"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism"
XP_054732658.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054731375.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054732412.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_054736752.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054743242.1	4	Reactome: R-HSA-3359463;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-196741	"Defective CUBN causes hereditary megaloblastic anemia 1";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054739532.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_054738642.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054740263.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054730523.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_054744996.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054736184.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054732478.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054725638.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_054745555.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054741969.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054736685.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_054743991.1	3	MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661	"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis"
XP_054740846.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054734359.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054743969.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054737963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054742136.1	3	KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45	"Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism"
XP_054742449.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054742594.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054735105.1	13	KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537	"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V"
XP_054732850.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Neddylation"
XP_054742667.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054740155.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-174178	"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054729324.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054733453.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054747305.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN"
XP_054744290.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054738548.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054725532.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054727643.1	18	MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC"
XP_054746922.1	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054735247.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054738764.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054744705.1	5	Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;MetaCyc: PWY-6129;Reactome: R-HSA-193048	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis"
XP_054728158.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054730319.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054726248.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_054742778.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054744815.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054730739.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054736884.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054729091.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054741496.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_054747641.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054727152.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054727727.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054725276.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054737542.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054736400.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054742712.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054739056.1	8	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054733064.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054736989.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_054726740.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054735633.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054747398.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054740569.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054727285.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054744647.1	11	KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184	"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054744574.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_054740591.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_054727410.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054733219.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739970.1	15	Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459	"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054733905.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape"
XP_054736444.1	5	KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33	"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis"
XP_054732822.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054743934.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054747554.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054734287.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_054744240.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054738598.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054742499.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054731948.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_054742544.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054741934.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_054727044.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054728972.1	18	MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7226	"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_054741309.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054734314.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726298.1	12	MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6309	"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_054739331.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054732216.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054737303.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054743309.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054727693.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054730153.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054728460.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054725266.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_054741903.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054745048.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054730096.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_054733663.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054747669.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054739317.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054740464.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054734224.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination"
XP_054737334.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054739960.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054731074.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_054747348.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_054727978.1	13	KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537	"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V"
XP_054726147.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054745134.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054739284.1	7	Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039	"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule"
XP_054735148.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054733074.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054728257.1	11	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302	"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"p38MAPK events";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"Thermogenesis";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_054737804.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054726790.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054733588.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054731746.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_054737341.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054736230.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_054737747.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054737379.1	13	Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation"
XP_054736876.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054743373.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054727407.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054741581.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054732757.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054740392.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054725284.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-913709;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins";"N-Glycan antennae elongation"
XP_054745333.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054738319.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_054733254.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054726681.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054741139.1	7	MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36	"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054727838.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_054728530.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054736318.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054744955.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054727308.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054733682.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054742966.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054732606.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_054727522.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-8849471	"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_054740486.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_054728806.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054744586.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054732367.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054738692.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054725737.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054727820.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_054728528.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054744946.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054743874.1	13	MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9	"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism"
XP_054726529.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054729025.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054728302.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_054743292.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054725472.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054738046.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054738739.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054745713.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054727395.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946	"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants"
XP_054725785.1	8	Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27	"Synthesis of PG";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism"
XP_054740503.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054743979.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_054741629.1	24	Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-5610780;Reactome: R-HSA-163560;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-5610783;Reactome: R-HSA-9634600;Reactome: R-HSA-5610785;Reactome: R-HSA-164378;Reactome: R-HSA-163358;Reactome: R-HSA-9010642;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-392517;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"RET signaling";"mTOR signaling pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"Degradation of GLI2 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"GLI3 is processed to GLI3R by the proteasome";"PKA activation in glucagon signalling";"PKA-mediated phosphorylation of key metabolic factors";"ROBO receptors bind AKAP5";"HDL assembly";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"PKA activation";"VEGFA-VEGFR2 Pathway";"Rap1 signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_054736228.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_054729003.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054742531.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054741979.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054727776.1	13	KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822	"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)"
XP_054732910.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis"
XP_054732089.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054744663.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054734174.1	52	Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-168325;Reactome: R-HSA-167242	"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_054735342.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25	"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system"
XP_054725877.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726904.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054730340.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054738125.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054747142.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662	"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling"
XP_054728772.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054734925.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802	"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3"
XP_054732608.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_054726809.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054742410.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054738624.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054727500.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054726442.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_054739985.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054739350.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054742237.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_054743224.1	6	Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;Reactome: R-HSA-8950505	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054738974.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174178	"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054727712.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054737042.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733697.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054733479.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_054739556.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054727836.1	12	Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054746931.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_054728718.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054738048.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_054726719.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054741287.1	5	MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26	"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism"
XP_054736071.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054728526.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054744948.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054727802.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054743703.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER"
XP_054738635.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054726933.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054733240.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054742094.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_054727594.1	5	KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_054727778.1	13	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation"
XP_054734309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054747653.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054738134.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054746149.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054730555.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054732466.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731659.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054726990.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054736226.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054740715.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054740324.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_054732536.1	9	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_054731946.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis"
XP_054747019.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054738141.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism"
XP_054725760.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_054730023.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054729846.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events"
XP_054725177.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054732957.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_054726873.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_054738596.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054736670.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054737119.1	6	KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-5099900	"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4"
XP_054734515.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054734629.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054732393.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054730005.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054740123.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054738803.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054742766.1	5	Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-381426	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_054735282.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_054731425.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11	"Glycine, serine and threonine metabolism";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
XP_054730964.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054725937.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054736267.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_054727102.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054731434.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054732999.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_054728916.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054745692.1	7	MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516	"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane"
XP_054725268.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_054747765.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054739521.1	10	MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_054725350.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054733434.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054732328.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_054737535.1	83	Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-5654720;Reactome: R-HSA-8856825;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-180336;Reactome: R-HSA-74751;Reactome: R-HSA-182971;Reactome: R-HSA-9607240;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-8875555;Reactome: R-HSA-1250196;Reactome: R-HSA-2428933;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640;Reactome: R-HSA-9634285;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-8983432;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-5673001;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-2871796;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-8853334;Reactome: R-HSA-983695;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-1250347;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-5654719;Reactome: R-HSA-5655291;Reactome: R-HSA-8875360;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-5654689;Reactome: R-HSA-8865999;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-9027284;Reactome: R-HSA-912631;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-5655253;Reactome: R-HSA-1839117;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-5654710;Reactome: R-HSA-6807004;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-5654704;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-8856828;Reactome: R-HSA-5654699;Reactome: R-HSA-5663213;Reactome: R-HSA-180292	"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"PI-3K cascade:FGFR4";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"SHC1 events in EGFR signaling";"Insulin receptor signalling cascade";"EGFR downregulation";"FLT3 Signaling";"NCAM signaling for neurite out-growth";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"MET activates RAP1 and RAC1";"SHC1 events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"Interleukin-15 signaling";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"RAF/MAP kinase cascade";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"FCERI mediated MAPK activation";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR3 fusions in cancer";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Signalling to RAS";"STAT5 Activation";"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"SHC1 events in ERBB4 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"PIP3 activates AKT signaling";"MET receptor recycling";"SHC-mediated cascade:FGFR4";"Signaling by FGFR4 in disease";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal regulatory protein family interactions";"MET activates RAS signaling";"PI-3K cascade:FGFR1";"MET activates PTPN11";"Tie2 Signaling";"Spry regulation of FGF signaling";"Erythropoietin activates RAS";"Regulation of signaling by CBL";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"Signaling by FGFR2 in disease";"Signaling by cytosolic FGFR1 fusion mutants";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"PI-3K cascade:FGFR3";"Negative regulation of MET activity";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"Signal attenuation";"Downstream signal transduction";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR3";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR2";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome"
XP_054733380.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_054727050.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_054732502.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin"
XP_054731380.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_054729439.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054746871.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054741741.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054735591.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054733996.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis"
XP_054737429.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054743423.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes"
XP_054726863.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_054733115.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_054738546.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_054740413.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_054726754.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054729525.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054736168.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054738191.1	6	MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_054734753.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054743888.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054728028.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054738169.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-6383	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_054725826.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399	"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy"
XP_054726246.1	5	Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472	"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054740025.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_054732589.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054737353.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054725595.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_054746068.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
XP_054728156.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054745153.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054728821.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054730635.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_054734186.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_054747482.1	52	Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-203927;Reactome: R-HSA-167246;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"MicroRNA (miRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER"
XP_054743081.1	3	KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17	"Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism"
XP_054736507.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054733539.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054743498.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054725278.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054747775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054734363.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054728093.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054725322.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Insulin receptor recycling";"Ion channel transport"
XP_054742407.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054726255.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_054732971.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054725151.1	2	Reactome: R-HSA-8981607;Reactome: R-HSA-203615	"Intracellular oxygen transport";"eNOS activation"
XP_054732949.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054727022.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054732262.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054729534.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054744086.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054733181.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054741791.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054746899.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-389957	"Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054735541.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054742308.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054741769.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054728207.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_054743791.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730134.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_054743397.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054728030.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054739602.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054731815.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054729541.1	5	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"EPHB-mediated forward signaling"
XP_054743188.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742120.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_054736057.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054747192.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054738891.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054732301.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054730596.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054730141.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054726580.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type"
XP_054733815.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054729915.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054738023.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054729196.1	4	KEGG: 00908+2.5.1.75;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"Zeatin biosynthesis";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_054728631.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054730333.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054733088.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054732020.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling"
XP_054743680.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054731204.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054732656.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054731088.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054739508.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_054731469.1	40	Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6796648;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-167160;Reactome: R-HSA-113418	"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"TP53 Regulates Transcription of DNA Repair Genes";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"mRNA Capping";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex"
XP_054738415.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_054731647.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_054731491.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054726492.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054742630.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727544.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054727677.1	5	Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_054727499.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1"
XP_054739595.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_054736099.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054732645.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054727927.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_054728121.1	34	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-8939236;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-69202;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-113418	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex"
XP_054735503.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054732817.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054742693.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739167.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054735896.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_054732144.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054726940.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054747239.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054742138.1	3	KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45	"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation"
XP_054728617.1	5	Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_054745354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726882.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_054730834.1	8	MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18	"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione metabolism"
XP_054733881.1	13	Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054733705.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_054735619.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054725636.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054726618.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054741870.1	42	Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-110329;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-5617472	"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"HDACs deacetylate histones";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Cleavage of the damaged pyrimidine";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054738636.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054739191.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_054728525.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054736573.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054747000.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725788.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054747410.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix"
XP_054735617.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054740832.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383	"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation"
XP_054736225.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054727497.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-201688	"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"WNT mediated activation of DVL"
XP_054727679.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054727641.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054747152.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054732465.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054730268.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054728273.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054743518.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730350.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054745276.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054730545.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054731921.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054747643.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054738126.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054729093.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054733671.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_054725280.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735856.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054740530.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054742653.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054729644.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_054739555.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054727835.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors"
XP_054738602.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054747094.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054731368.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_054735762.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054725869.1	12	KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13	"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis"
XP_054744958.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054728534.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054743170.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054728196.1	7	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-983168	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Protein ubiquitination";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054734730.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054726208.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054725986.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054735030.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054735577.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054741767.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054747766.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054741361.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054739891.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054745045.1	17	KEGG: 04151+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69601;Reactome: R-HSA-6804756;Reactome: R-HSA-8953750;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of TP53 Activity through Phosphorylation";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054727603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054743361.1	40	Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-167287;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-73776	"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"HIV elongation arrest and recovery";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape"
XP_054730032.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054726084.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-180585	"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Separation of Sister Chromatids";"Ub-specific processing proteases";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G"
XP_054739005.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054747345.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054743678.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_054738151.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659	"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis"
XP_054733537.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054736279.1	8	MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-6611	"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V"
XP_054742409.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054735821.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731070.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_054737330.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054740918.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_054740460.1	14	MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105	"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport"
XP_054742019.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054735145.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054746424.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_054732587.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054737272.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_054742540.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054738595.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054743357.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054729845.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054734967.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054730521.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054743930.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054738826.1	18	MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7222;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_054737328.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054731945.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_054734238.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054732773.1	12	Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054733511.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)"
XP_054741357.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054726700.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054741612.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054737427.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054728981.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054741993.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-69273;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"Cyclin A/B1/B2 associated events during G2/M transition";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_054727187.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054728053.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054742765.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054745056.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054726295.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation"
XP_054743993.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054734310.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054730006.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054738167.1	13	KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7736	"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis"
XP_054734516.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054737961.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054739788.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054740622.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_054743371.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_054743349.1	19	Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026	"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Platelet sensitization by LDL";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"VLDL assembly";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Chylomicron clearance"
XP_054739841.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054739125.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054744818.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054728474.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054741160.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054725834.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054729485.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054741349.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054741777.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054747031.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054741371.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054737589.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054730636.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_054742504.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054738556.1	3	MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531	"Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus"
XP_054726683.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054745737.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054745331.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054739974.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_054743668.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_054737131.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054739624.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054726744.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054734252.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054731116.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054725333.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054728282.1	4	Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054737117.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_054747838.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_054739635.1	13	MetaCyc: PWY-7222;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184	"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054729526.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054744872.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054738545.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054733116.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054739048.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740158.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_054747522.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054732854.1	2	Reactome: R-HSA-5689880;MetaCyc: PWY-7511	"Ub-specific processing proteases";"Protein ubiquitination"
XP_054725390.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054745960.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054725141.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054740650.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054730602.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_054737621.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054742482.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054730058.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054738760.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054743406.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)"
XP_054726245.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_054729600.1	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
XP_054739596.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_054746814.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_054734701.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054732646.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054736563.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054731657.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751	"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated"
XP_054747628.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054739141.1	56	Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Ub-specific processing proteases";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis"
XP_054740051.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_054739179.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054732782.1	8	MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5394;MetaCyc: PWY-3581	"Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"Folate biosynthesis";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis I"
XP_054725635.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054733706.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_054738689.1	17	Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054735320.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_054746919.1	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054730322.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054739803.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_054735718.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054737283.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054733312.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054730151.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_054727691.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054741901.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-167590	"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD4 Down-regulation"
XP_054730826.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841	"Metabolism of folate and pterines";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)"
XP_054726807.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_054731661.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054735338.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_054738521.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054726662.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054733816.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_054729916.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054744172.1	13	KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2206308;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-2022857	"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"MPS IV - Morquio syndrome B";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Keratan sulfate degradation"
XP_054725624.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_054726076.1	6	Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527	"Galactose catabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_054733699.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054747912.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054729043.1	14	MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969	"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_054731816.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054733378.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054737645.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054727554.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054735772.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054738416.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054728439.1	5	Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305	"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D"
XP_054732655.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054734666.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054747044.1	5	Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_054737038.1	33	Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813	"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids"
XP_054733222.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054729567.1	30	Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-2894862;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-1170546;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323	"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Prolactin receptor signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling"
XP_054729936.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway"
XP_054739080.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-1268020	"Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import"
XP_054730157.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813	"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids"
XP_054732382.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054728865.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054726317.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition"
XP_054731270.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054738584.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Formation of apoptosome";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_054729557.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_054739575.1	14	KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-75109	"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Triglyceride biosynthesis"
XP_054731651.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599	"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Pentose and glucuronate interconversions";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate"
XP_054735230.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054738436.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054735876.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054733651.1	5	MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88	"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism";"Alanine, aspartate and glutamate metabolism"
XP_054727748.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054746825.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054737018.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_054734283.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_054746179.1	8	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation"
XP_054729599.1	4	KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion"
XP_054731778.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_054745256.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_054726095.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054728253.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054740789.1	5	MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)"
XP_054730576.1	18	Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Acyl chain remodelling of PE";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054725114.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054733778.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054744138.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054742329.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727659.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_054730161.1	16	MetaCyc: PWY-5749;KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5	"Itaconate degradation";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism"
XP_054735372.1	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_054725529.1	7	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054733802.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054732886.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_054733667.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)"
XP_054737072.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054726737.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Aggrephagy";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054731667.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221	"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway"
XP_054741907.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_054731802.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_054726785.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_054731449.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054725313.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731136.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054737137.1	17	KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599	"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency"
XP_054746974.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054739529.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_054743478.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054742609.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_054745731.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6364;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_054730857.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054745076.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054745337.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054732969.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054744776.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054744031.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054733136.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054730068.1	10	Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-9648895;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-72731;Reactome: R-HSA-72649	"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Recycling of eIF2:GDP";"Translation initiation complex formation"
XP_054729738.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054741771.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735561.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054725704.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054732753.1	14	Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167152	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_054736413.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_054745438.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054728664.1	4	MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315	"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_054743377.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_054743036.1	7	Reactome: R-HSA-9020265;Reactome: R-HSA-9018896;Reactome: R-HSA-2142691;Reactome: R-HSA-9018681;Reactome: R-HSA-9023661;Reactome: R-HSA-6798695;Reactome: R-HSA-9018676	"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(S)-resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins";"Biosynthesis of E-series 18(R)-resolvins";"Neutrophil degranulation";"Biosynthesis of D-series resolvins"
XP_054734131.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054737252.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054738258.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054741412.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054725223.1	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_054730861.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054729876.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054744838.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging"
XP_054736259.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054747872.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation"
XP_054727955.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_054743412.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054725790.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_054736148.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054742086.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054727586.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054725205.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_054725919.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_054726101.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-2426168;MetaCyc: PWY-5667;Reactome: R-HSA-8931987;Reactome: R-HSA-75109;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-9018519;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055	"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Activation of gene expression by SREBF (SREBP)";"CDP-diacylglycerol biosynthesis I";"RUNX1 regulates estrogen receptor mediated transcription";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Estrogen-dependent gene expression";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis"
XP_054740507.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054725575.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054736034.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_054733102.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054740277.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264	"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_054746005.1	52	Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-203927;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-1834949;Reactome: R-HSA-167287	"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"MicroRNA (miRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cytosolic sensors of pathogen-associated DNA";"HIV elongation arrest and recovery"
XP_054736247.1	10	KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397	"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_054726483.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_054745922.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054735827.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane"
XP_054741468.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730078.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_054725159.1	32	Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167172	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome"
XP_054726532.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054738722.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054732629.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_054738157.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-6383	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_054725248.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-171007	"mTOR signaling pathway";"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events"
XP_054726828.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054737793.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054731189.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054743799.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP"
XP_054728547.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054743761.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054735166.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054740251.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741799.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_054728924.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_054735494.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054735571.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_054741761.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054727115.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054746869.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_054741367.1	7	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054729611.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054725740.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054741606.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054738161.1	13	MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410	"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis"
XP_054726893.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054725197.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_054733022.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054737421.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505	"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054739954.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054733966.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054734328.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054743606.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054738576.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054740267.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054730527.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway"
XP_054736690.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_054746481.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054726300.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-7901	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine"
XP_054739435.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054741757.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_054741351.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054733517.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054739487.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054726830.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054737310.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_054743757.1	7	MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism"
XP_054727539.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054736069.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054739565.1	20	MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7291;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism"
XP_054733984.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054731260.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054731358.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_054738068.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054741326.1	10	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Sphingolipid metabolism"
XP_054747327.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054744237.1	5	KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279	"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_054727088.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054730931.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873	"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation"
XP_054736214.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054742588.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054725859.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054743520.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_054743326.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054727574.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054733358.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054733457.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_054745295.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway"
XP_054732446.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_054729400.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054733889.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism"
XP_054726620.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695	"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation"
XP_054744152.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054735866.1	24	Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-2730905;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-444257;Reactome: R-HSA-354192;Reactome: R-HSA-6804757	"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"RSK activation";"Integrin signaling";"Regulation of TP53 Degradation"
XP_054736781.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054742663.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054736805.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314	"Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex"
XP_054729201.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054738616.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_054725897.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054728639.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054726193.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054747217.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727705.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054727881.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054740226.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054726045.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054732455.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054736898.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054730566.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054730258.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747430.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054727233.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054732309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054739159.1	10	Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_054744094.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747384.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054731461.1	6	KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_054729827.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism"
XP_054727723.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731499.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_054737062.1	57	Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815	"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Neutrophil degranulation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D"
XP_054733461.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_054733499.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054733544.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27	"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Cysteine and methionine metabolism"
XP_054731927.1	7	KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16	"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_054732408.1	6	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-3371453;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Regulation of HSF1-mediated heat shock response";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_054738424.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054730919.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054739157.1	10	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Ub-specific processing proteases";"Human papillomavirus infection"
XP_054730205.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054732018.1	7	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6798695	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Neutrophil degranulation"
XP_054733929.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_054740688.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054739722.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054731641.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747	"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated"
XP_054730575.1	18	Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482839	"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE"
XP_054733641.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054733497.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054726096.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination"
XP_054727758.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054745255.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054742932.1	31	MetaCyc: PWY-7723;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-6799;Reactome: R-HSA-2426168;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-8047;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-5989;MetaCyc: PWY-7664;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-6113	"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Activation of gene expression by SREBF (SREBP)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"";"Superpathway of mycolate biosynthesis"
XP_054733398.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_054740563.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054747219.1	7	KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054728637.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054742118.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_054731398.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_054728685.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054743542.1	5	MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_054729674.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_054732307.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054745182.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054747064.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_054739576.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-1483191;Reactome: R-HSA-4419969	"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Synthesis of PC";"Depolymerisation of the Nuclear Lamina"
XP_054730704.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615	"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation"
XP_054728866.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054729987.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_054732072.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism"
XP_054739161.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_054731459.1	40	Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-73776	"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"mRNA Capping";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape"
XP_054729935.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054736389.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054731887.1	5	Reactome: R-HSA-162710;Reactome: R-HSA-4717374;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377	"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_054745754.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054744054.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054730313.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054732495.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054733323.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036	"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_054742172.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054735875.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054738435.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054727649.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054725489.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054727585.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054737864.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054740269.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054733519.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_054747513.1	14	Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.42;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053	"Peroxisomal protein import";"Plasmalogen biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II"
XP_054727956.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400	"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054740291.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation"
XP_054732743.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054742570.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054727537.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054729875.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054728884.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054731625.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221	"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway"
XP_054738197.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism"
XP_054729514.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054725370.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_054743963.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054733603.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054738740.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_054728010.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054746636.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_054728989.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism";"Cyanoamino acid metabolism"
XP_054731603.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054726988.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054732137.1	12	Reactome: R-HSA-418885;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476	"DCC mediated attractive signaling";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Rho GTPase cycle";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"G alpha (q) signalling events"
XP_054741963.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054741140.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054731187.1	3	MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5	"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_054744775.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054737363.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054740433.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054745075.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054743369.1	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054735924.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054729639.1	8	Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-5340588;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-4086398;Reactome: R-HSA-4608870;Reactome: R-HSA-373080	"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Ca2+ pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)"
XP_054736026.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054745386.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_054741369.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054736650.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054744396.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054730681.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054743087.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054736501.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054746126.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054743605.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054738575.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054738733.1	5	Reactome: R-HSA-2426168;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis"
XP_054727908.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_054745719.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_054744019.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054744842.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054732220.1	13	KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6370;MetaCyc: PWY-6842;MetaCyc: PWY-7112;Reactome: R-HSA-196836	"Glutathione metabolism";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Vitamin C (ascorbate) metabolism"
XP_054742560.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054738205.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054735559.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054734524.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054738080.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054741605.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054736918.1	8	MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_054737874.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054732793.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054742745.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054741973.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741104.1	6	Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537	"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"HDACs deacetylate histones";"HCMV Early Events";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex"
XP_054732951.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054732083.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054740613.1	3	MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106	"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)"
XP_054743104.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_054737941.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054738147.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054738223.1	57	Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Neddylation";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"UCH proteinases";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling"
XP_054725258.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_054726505.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding"
XP_054741341.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054730388.1	2	Reactome: R-HSA-5654726;Reactome: R-HSA-190373	"Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation"
XP_054735664.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of the pre-replicative complex"
XP_054732516.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054743190.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054737581.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054732728.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054737373.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_054731033.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054743379.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054739849.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054738704.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054742756.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054728444.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_054727116.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054737139.1	7	MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539	"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism"
XP_054745442.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054732238.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_054743133.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_054725750.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events"
XP_054739527.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054735165.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054730859.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054730487.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813	"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids"
XP_054738298.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054736106.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054736261.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054733669.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_054742231.1	4	KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9	"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate"
XP_054733691.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054743480.1	4	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054727312.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_054726046.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054740225.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054733447.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054741909.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_054727706.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_054738529.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054725944.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054738615.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_054731447.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054726692.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054731691.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054740381.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_054741334.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054730740.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054743804.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054727657.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_054742327.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054741592.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054730197.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_054725871.1	12	MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1861	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054740735.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054740573.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054735742.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054728007.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054742958.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054743325.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054728417.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054740315.1	11	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_054727222.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054732062.1	5	Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_054739171.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054735009.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054727378.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_054742384.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054728230.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054739566.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_054736806.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-6783310;Reactome: R-HSA-5689880	"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway";"Ub-specific processing proteases"
XP_054743303.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054727661.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054725078.1	2	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054743281.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054742162.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054727699.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735865.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745109.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054741303.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735	"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis"
XP_054727732.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054732445.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054745296.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054738681.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621	"Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism"
XP_054726055.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054736336.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054731256.1	12	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-193692;Reactome: R-HSA-982772;Reactome: R-HSA-177929	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"TNF signaling";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Regulated proteolysis of p75NTR";"Growth hormone receptor signaling";"Signaling by EGFR"
XP_054742964.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054741228.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054740484.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054730766.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054743372.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038	"Platelet sensitization by LDL";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance"
XP_054739355.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054739842.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_054744584.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054736515.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_054736629.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054729749.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054742280.1	17	MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37	"Reductive TCA cycle II";"Methylaspartate cycle";"Methane metabolism";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_054728334.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054733568.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_054742415.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054736979.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054734178.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Neutrophil degranulation";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054743738.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_054728215.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_054726908.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-983168	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742869.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054738120.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_054740800.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633	"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054741738.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054742023.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054737460.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054727523.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471	"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_054734251.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054736874.1	30	Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-2564830;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167161	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"mRNA Capping";"HIV Transcription Initiation"
XP_054737132.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054745449.1	12	Reactome: R-HSA-429947;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054747689.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_054729150.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054738138.1	5	MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis"
XP_054740272.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054733107.1	4	Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;Reactome: R-HSA-6798695	"MPS VII - Sly syndrome";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Neutrophil degranulation"
XP_054740710.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727774.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_054745306.1	4	KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_054738912.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054728281.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054738693.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054732633.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054740502.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054747521.1	1	Reactome: R-HSA-416476	"G alpha (q) signalling events"
XP_054734450.1	9	MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8	"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism"
XP_054744871.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054740894.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054730356.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_054725473.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054734267.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054729002.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054728714.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_054744527.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054741230.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054747877.1	9	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_054742481.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744944.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054741007.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054736373.1	182	Reactome: R-HSA-936964;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-9033241;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-8849469;Reactome: R-HSA-9637628;Reactome: R-HSA-5654733;Reactome: R-HSA-6804756;Reactome: R-HSA-168638;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5689877;Reactome: R-HSA-4641258;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-72689;Reactome: R-HSA-182971;Reactome: R-HSA-9615710;Reactome: R-HSA-5676590;Reactome: R-HSA-937072;Reactome: R-HSA-175474;Reactome: R-HSA-5205685;Reactome: R-HSA-450321;Reactome: R-HSA-8941858;Reactome: R-HSA-5654727;Reactome: R-HSA-4641257;Reactome: R-HSA-156902;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-201681;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8875360;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-209543;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-917729;Reactome: R-HSA-1358803;Reactome: R-HSA-5693565;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-2979096;Reactome: R-HSA-5689896;Reactome: R-HSA-5658442;Reactome: R-HSA-5689901;Reactome: R-HSA-5357956;Reactome: R-HSA-2173791;Reactome: R-HSA-8863795;Reactome: R-HSA-975163;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-174490;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-1169408;Reactome: R-HSA-68827;Reactome: R-HSA-5655862;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9014325;Reactome: R-HSA-4641263;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-3134975;Reactome: R-HSA-3769402;Reactome: R-HSA-5610783;Reactome: R-HSA-168928;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-174084;Reactome: R-HSA-975110;Reactome: R-HSA-5696394;Reactome: R-HSA-75815;Reactome: R-HSA-5684264;Reactome: R-HSA-5696400;Reactome: R-HSA-72706;Reactome: R-HSA-162588;Reactome: R-HSA-69601;Reactome: R-HSA-2559582;Reactome: R-HSA-6781823;Reactome: R-HSA-975957;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-937039;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-6804757;Reactome: R-HSA-110312;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9645460;Reactome: R-HSA-9613829;Reactome: R-HSA-174048;Reactome: R-HSA-3785653;Reactome: R-HSA-5656169;Reactome: R-HSA-1799339;Reactome: R-HSA-8866652;Reactome: R-HSA-8951664;Reactome: R-HSA-3322077;Reactome: R-HSA-9013973;Reactome: R-HSA-156827;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-937041;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-901032;Reactome: R-HSA-110314;Reactome: R-HSA-8948747;Reactome: R-HSA-5654726;Reactome: R-HSA-937042;Reactome: R-HSA-6783310;Reactome: R-HSA-174113;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-72764;Reactome: R-HSA-168927;Reactome: R-HSA-8856828;Reactome: R-HSA-2672351;Reactome: R-HSA-2559585;Reactome: R-HSA-8876493;Reactome: R-HSA-211733;Reactome: R-HSA-2173796;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-912631;Reactome: R-HSA-1234176;Reactome: R-HSA-209560;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-2691232;Reactome: R-HSA-2559580;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-72702;Reactome: R-HSA-450302;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2122947;Reactome: R-HSA-5696395;Reactome: R-HSA-8948751;Reactome: R-HSA-445989;Reactome: R-HSA-5357905;Reactome: R-HSA-5675221;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-5358346;Reactome: R-HSA-72649;Reactome: R-HSA-69541;Reactome: R-HSA-1236382;Reactome: R-HSA-9633012;Reactome: R-HSA-8866654;Reactome: R-HSA-6804760;Reactome: R-HSA-6781827;Reactome: R-HSA-69481;Reactome: R-HSA-977225;Reactome: R-HSA-69231;Reactome: R-HSA-450408;Reactome: R-HSA-6782135;Reactome: R-HSA-2173795;Reactome: R-HSA-2894862;Reactome: R-HSA-192823	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"Peroxisomal protein import";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Modulation by Mtb of host immune system";"Negative regulation of FGFR4 signaling";"Regulation of TP53 Activity through Phosphorylation";"NOD1/2 Signaling Pathway";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Josephin domain DUBs";"Degradation of DVL";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Formation of a pool of free 40S subunits";"EGFR downregulation";"Late endosomal microautophagy";"NIK-->noncanonical NF-kB signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Assembly Of The HIV Virion";"Pink/Parkin Mediated Mitophagy";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Regulation of RUNX3 expression and activity";"Negative regulation of FGFR2 signaling";"Degradation of AXIN";"Peptide chain elongation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TCF dependent signaling in response to WNT";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"p75NTR recruits signalling complexes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of ERBB2:ERBB3 signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"Regulation of RAS by GAPs";"Metalloprotease DUBs";"TNFR1-induced NFkappaB signaling pathway";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Membrane binding and targetting of GAG proteins";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"ISG15 antiviral mechanism";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLK";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of FZD by ubiquitination";"Ub-specific processing proteases";"Negative regulation of MET activity";"Regulation of innate immune responses to cytosolic DNA";"Deactivation of the beta-catenin transactivating complex";"Degradation of GLI2 by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Autodegradation of Cdh1 by Cdh1:APC/C";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DNA Damage Recognition in GG-NER";"Ubiquitin-dependent degradation of Cyclin D";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dual Incision in GG-NER";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Budding and maturation of HIV virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of TC-NER Pre-Incision Complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"IRAK1 recruits IKK complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Regulation of TP53 Degradation";"Translesion synthesis by REV1";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Alpha-protein kinase 1 signaling pathway";"Chaperone Mediated Autophagy";"APC/C:Cdc20 mediated degradation of Cyclin B";"Myoclonic epilepsy of Lafora";"Termination of translesion DNA synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Neddylation";"Glycogen synthesis";"TICAM1-dependent activation of IRF3/IRF7";"L13a-mediated translational silencing of Ceruloplasmin expression";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IKK complex recruitment mediated by RIP1";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"ER Quality Control Compartment (ERQC)";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of PTEN localization";"Negative regulation of FGFR1 signaling";"IRAK2 mediated activation of TAK1 complex";"Fanconi Anemia Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"Eukaryotic Translation Termination";"TICAM1, RIP1-mediated IKK complex recruitment";"Clathrin-mediated endocytosis";"Stimuli-sensing channels";"Oncogene Induced Senescence";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Aggrephagy";"Selenocysteine synthesis";"Regulation of signaling by CBL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NF-kB is activated and signals survival";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Oxidative Stress Induced Senescence";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Ribosomal scanning and start codon recognition";"activated TAK1 mediates p38 MAPK activation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of Incision Complex in GG-NER";"Regulation of PTEN stability and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TNFR1 signaling";"Negative regulation of MAPK pathway";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"Hedgehog ligand biogenesis";"Translation initiation complex formation";"Stabilization of p53";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Activity through Methylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"G2/M Checkpoints";"Amyloid fiber formation";"Cyclin D associated events in G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dual incision in TC-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Viral mRNA Translation"
XP_054740961.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription"
XP_054727598.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_054742098.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796	"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription"
XP_054747416.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_054745626.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054738031.1	4	Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054735658.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054745050.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054730000.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054739142.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751	"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity"
XP_054732488.1	16	Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-1250342;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-1236394;Reactome: R-HSA-5673001	"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"PI3K events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"Signaling by ERBB4";"RAF/MAP kinase cascade"
XP_054732069.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054725540.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054730410.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054740608.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054734510.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054727739.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054742546.1	3	KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)"
XP_054743557.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-182971;Reactome: R-HSA-432720;Reactome: R-HSA-917729	"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"EGFR downregulation";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054729552.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054731717.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054727046.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379	"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events"
XP_054735150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054736174.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054732387.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054732781.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054727913.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-68877	"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase"
XP_054738820.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_054737528.1	83	Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-2424491;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285;Reactome: R-HSA-2871796;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-5654695;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-983695;Reactome: R-HSA-8853334;Reactome: R-HSA-2219530;Reactome: R-HSA-5637810;Reactome: R-HSA-9028731;Reactome: R-HSA-2029482;Reactome: R-HSA-1250347;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-5654720;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-5655302;Reactome: R-HSA-5654712;Reactome: R-HSA-8856825;Reactome: R-HSA-512988;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-1963640;Reactome: R-HSA-9028335;Reactome: R-HSA-1839117;Reactome: R-HSA-5655253;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-5654710;Reactome: R-HSA-6807004;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-5654699;Reactome: R-HSA-180292;Reactome: R-HSA-5663213;Reactome: R-HSA-1433559;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-5654704;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-5654719;Reactome: R-HSA-5654689;Reactome: R-HSA-8865999;Reactome: R-HSA-912631;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596	"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"DAP12 signaling";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2";"FCERI mediated MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"PI-3K cascade:FGFR2";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Signalling to RAS";"STAT5 Activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by Aberrant PI3K in Cancer";"Constitutive Signaling by EGFRvIII";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of actin dynamics for phagocytic cup formation";"SHC1 events in ERBB4 signaling";"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"PI-3K cascade:FGFR4";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"Signaling by FGFR1 in disease";"FRS-mediated FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"NCAM signaling for neurite out-growth";"RET signaling";"FLT3 Signaling";"EGFR downregulation";"GRB2 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR2 in disease";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"PI-3K cascade:FGFR3";"Negative regulation of MET activity";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Signal attenuation";"Downstream signal transduction";"SHC-mediated cascade:FGFR2";"GAB1 signalosome";"RHO GTPases Activate WASPs and WAVEs";"Regulation of KIT signaling";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"PIP3 activates AKT signaling";"MET receptor recycling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"Signal regulatory protein family interactions";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR1";"MET activates PTPN11";"Regulation of signaling by CBL";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling"
XP_054730152.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054727692.1	2	Reactome: R-HSA-3772470;Reactome: R-HSA-201681	"Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT"
XP_054739473.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054730321.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054737302.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054745136.1	5	Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3	"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_054739286.1	7	Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039	"Synthesis of PG";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_054744149.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_054728133.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_054726699.1	5	Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013	"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_054732715.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054731950.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_054741902.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054731807.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_054738522.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054731662.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054731076.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054727055.1	11	Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163615	"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation"
XP_054731337.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054737336.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054733662.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054744360.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054737530.1	83	Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-8851805;Reactome: R-HSA-391160;Reactome: R-HSA-5654719;Reactome: R-HSA-8875656;Reactome: R-HSA-1257604;Reactome: R-HSA-389359;Reactome: R-HSA-2730905;Reactome: R-HSA-912631;Reactome: R-HSA-1295596;Reactome: R-HSA-210993;Reactome: R-HSA-9027284;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-6807004;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-5654710;Reactome: R-HSA-5654726;Reactome: R-HSA-2871809;Reactome: R-HSA-1839117;Reactome: R-HSA-5654727;Reactome: R-HSA-9664565;Reactome: R-HSA-5655253;Reactome: R-HSA-180292;Reactome: R-HSA-5663213;Reactome: R-HSA-5654699;Reactome: R-HSA-5654704;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-8856828;Reactome: R-HSA-5654688;Reactome: R-HSA-1236382;Reactome: R-HSA-186763;Reactome: R-HSA-74749;Reactome: R-HSA-180336;Reactome: R-HSA-74751;Reactome: R-HSA-8856825;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-5654720;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-1963640;Reactome: R-HSA-9028335;Reactome: R-HSA-8853659;Reactome: R-HSA-375165;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-512988;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-2871796;Reactome: R-HSA-5673001;Reactome: R-HSA-2424491;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-9634285;Reactome: R-HSA-8983432;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-912526;Reactome: R-HSA-109704;Reactome: R-HSA-1433557;Reactome: R-HSA-1250347;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-983695;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-8853334	"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"MET activates RAS signaling";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR4";"MET receptor recycling";"PIP3 activates AKT signaling";"CD28 dependent Vav1 pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of signaling by CBL";"Spry regulation of FGF signaling";"Tie2 Signaling";"Erythropoietin activates RAS";"MET activates PTPN11";"PI-3K cascade:FGFR1";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"Negative regulation of MET activity";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"PI-3K cascade:FGFR3";"Negative regulation of FGFR1 signaling";"FCERI mediated Ca+2 mobilization";"Signaling by cytosolic FGFR1 fusion mutants";"Negative regulation of FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR2 in disease";"GAB1 signalosome";"RHO GTPases Activate WASPs and WAVEs";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR3";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR1";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Downstream signal transduction";"Signal attenuation";"SHC1 events in EGFR signaling";"Insulin receptor signalling cascade";"Cargo recognition for clathrin-mediated endocytosis";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"PI-3K cascade:FGFR4";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"GRB2 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"RET signaling";"NCAM signaling for neurite out-growth";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"FLT3 Signaling";"EGFR downregulation";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FCERI mediated MAPK activation";"RAF/MAP kinase cascade";"DAP12 signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"Constitutive Signaling by Overexpressed ERBB2";"Interleukin-15 signaling";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"Interleukin receptor SHC signaling";"PI3K Cascade";"Signaling by SCF-KIT";"SHC1 events in ERBB4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signalling to RAS";"STAT5 Activation";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by FGFR3 fusions in cancer"
XP_054738838.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054734049.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054735771.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054725355.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054730094.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054735749.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054739653.1	5	MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation"
XP_054741599.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054731438.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054747760.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684	"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state"
XP_054725409.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_054747177.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054725264.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_054738017.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054743561.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054746948.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-2173796;Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947	"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054737593.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins"
XP_054736665.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"MAP2K and MAPK activation";"Neutrophil degranulation"
XP_054741010.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054732079.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054744157.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054740020.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054735122.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054736496.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727642.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054746923.1	5	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism"
XP_054747278.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054725533.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_054744232.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054740301.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733110.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054730120.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168333	"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_054738345.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin"
XP_054735089.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054731922.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054729538.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054738550.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054733672.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_054735910.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_054728035.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054737067.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054732848.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054740144.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739054.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054739729.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054744206.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054727153.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054726368.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054740645.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054738601.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054742713.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054725274.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054741166.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040	"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054737543.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054736886.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_054747212.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_054747770.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_054730630.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_054735761.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054741362.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_054733084.1	17	MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6620;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-74217	"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine salvage"
XP_054736991.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054727354.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_054734952.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054743685.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054730776.1	11	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_054731084.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054743362.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054728542.1	9	Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781	"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression"
XP_054733208.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_054745768.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054731578.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6"
XP_054729799.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054738152.1	13	MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-5122;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659	"Linalool biosynthesis I";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis"
XP_054738727.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway"
XP_054729910.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054732413.1	5	KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054736753.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054740131.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054742879.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054739533.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_054729757.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054726511.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_054745260.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_054730838.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054737271.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054745358.1	5	MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279	"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)"
XP_054740844.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054746375.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731700.1	22	Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257	"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion"
XP_054737158.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_054741243.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054738643.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054734422.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054729606.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_054730017.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054732640.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_054744994.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054730407.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054727548.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054736186.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054728982.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054738094.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054741866.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis"
XP_054747867.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_054740621.1	1	Reactome: R-HSA-71262	"Carnitine synthesis"
XP_054747058.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731027.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054731863.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054730355.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054730019.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054732460.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_054747023.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_054730409.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054729963.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054747869.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_054733863.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054735982.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054731029.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054734279.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054747891.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054738192.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054746183.1	8	MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115	"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_054742032.1	25	Reactome: R-HSA-392851;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-381771;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-456926	"Prostacyclin signalling through prostacyclin receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054729759.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054729024.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054727532.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054734992.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054747280.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054737123.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054725784.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880	"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases"
XP_054727394.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948	"Platelet degranulation";"Smooth Muscle Contraction";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants"
XP_054738463.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_054746756.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054744388.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054728822.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054743082.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579	"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange"
XP_054725152.1	2	Reactome: R-HSA-8981607;Reactome: R-HSA-203615	"Intracellular oxygen transport";"eNOS activation"
XP_054742877.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054736516.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054726539.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751	"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated"
XP_054725321.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_054745929.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_054728538.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054727830.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244	"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation"
XP_054739550.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054744954.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054735542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054732299.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054736967.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054732261.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054741792.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054733182.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054745398.1	7	MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_054730346.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054744859.1	13	Reactome: R-HSA-1442490;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-186797;Reactome: R-HSA-3000178	"Collagen degradation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Integrin cell surface interactions";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"NCAM1 interactions";"Extracellular matrix organization";"Signaling by PDGF";"ECM proteoglycans"
XP_054739601.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054725285.1	7	KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;Reactome: R-HSA-69205;Reactome: R-HSA-1474151	"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Metabolism of folate and pterines";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054729797.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054740587.1	4	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER"
XP_054738239.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_054728799.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054738892.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_054735140.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054742985.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054742350.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054732302.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054729542.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_054743547.1	5	MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_054728367.1	16	Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174184	"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_054726815.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054731075.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_054727056.1	11	Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation"
XP_054733580.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054739968.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585	"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Oncogene Induced Senescence"
XP_054737781.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_054731580.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054732716.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054739285.1	7	Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561	"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III"
XP_054745040.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054737069.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054745634.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054731492.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054740042.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_054734735.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054726469.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40	"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism"
XP_054725356.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054739643.1	12	KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-1861;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13	"Methane metabolism";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_054725345.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054730286.1	9	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Thermogenesis"
XP_054735759.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_054742760.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054726290.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054728122.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695	"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054736926.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054730653.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054731940.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054741987.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054736445.1	5	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes"
XP_054729982.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)"
XP_054729840.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054733940.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054727045.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054735341.1	7	MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183	"Myo-inositol biosynthesis";"Phytate degradation I";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054747390.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054733065.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054742508.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054730192.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727418.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054734688.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054739978.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054741597.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727652.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_054745033.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054747141.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-139853;Reactome: R-HSA-381676	"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054736408.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054728771.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_054742278.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054733339.1	8	Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856828	"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Clathrin-mediated endocytosis"
XP_054730463.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054744147.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054726441.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_054731442.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054725838.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736885.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_054744814.1	8	MetaCyc: PWY-5154;KEGG: 00250+4.3.2.1;MetaCyc: PWY-5;MetaCyc: PWY-4983;KEGG: 00220+4.3.2.1;MetaCyc: PWY-7400;MetaCyc: PWY-4984;Reactome: R-HSA-70635	"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"Canavanine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Urea cycle";"Urea cycle"
XP_054745090.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737041.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727317.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054735133.1	7	MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_054741165.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555	"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events"
XP_054729480.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_054743073.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_054731339.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054747803.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis"
XP_054729215.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_054740646.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930	"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor"
XP_054738765.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_054736072.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054727737.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054742770.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054732389.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054747713.1	13	MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201	"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I"
XP_054733719.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054730729.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054739138.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054729303.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054728150.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_054745288.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054727801.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054738346.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054733990.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054738540.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054739630.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs"
XP_054728412.1	5	Reactome: R-HSA-4793954;MetaCyc: PWY-7918;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668	"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054729325.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054742826.1	12	Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73863	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Termination"
XP_054739044.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054736495.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_054736684.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_054745554.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_054740429.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054734269.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6	"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Tryptophan metabolism"
XP_054733873.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_054726946.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054743419.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-933541	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation"
XP_054734291.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_054741009.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054729623.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription"
XP_054736743.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484	"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_054726013.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054741419.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6811438	"RAB geranylgeranylation";"Intra-Golgi traffic"
XP_054731873.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_054730504.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription"
XP_054733109.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_054747103.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_054735833.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI"
XP_054740353.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054744114.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054736185.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054725138.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054725693.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054729605.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_054734880.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054727558.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054727101.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054739838.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054734582.1	8	KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901;Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27	"Propanoate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_054733374.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054726434.1	42	Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-5693565	"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Late Events";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054730533.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054732650.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054742867.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054743686.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_054735215.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054735909.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_054739522.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731374.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054747687.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054745447.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735480.1	14	MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5	"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism"
XP_054725978.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054732501.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054732158.1	7	MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"UTP and CTP dephosphorylation I"
XP_054729747.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054730590.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_054736627.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054727843.1	12	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054734490.1	3	KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_054735592.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054747134.1	5	MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-8013	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_054738653.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054726380.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054736977.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054740763.1	15	MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7383;Reactome: R-HSA-70171	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Purine metabolism";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis"
XP_054735703.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054726414.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_054743263.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054727683.1	4	KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922	"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_054737291.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054744841.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-1368108	"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054741263.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_054735235.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054727744.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054740242.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054726288.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054737404.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054735314.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054744974.1	3	KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_054740969.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054742857.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054730609.1	4	KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_054725172.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054743846.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation"
XP_054736589.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054731505.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054739085.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054738074.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_054739200.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054741342.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054744048.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054745748.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054727245.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054725610.1	4	MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;KEGG: 00513+3.2.1.114	"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054743855.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054736621.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054739011.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_054735224.1	17	Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-174414	"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Processive synthesis on the C-strand of the telomere"
XP_054729448.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144	"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling"
XP_054731774.1	3	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054735813.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745441.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054744134.1	58	Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5689901;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168	"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Metalloprotease DUBs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733774.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054736262.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054737047.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054729813.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_054727311.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_054727717.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054744596.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054733046.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736283.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1	"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_054732057.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_054747733.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_054731692.1	22	Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5675221	"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Negative regulation of MAPK pathway"
XP_054739932.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_054726691.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054730673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740164.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72649	"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Translation initiation complex formation"
XP_054747223.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054727420.1	11	MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675	"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Ammonia assimilation cycle II";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)"
XP_054741146.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054743474.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054740382.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054740665.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054746978.1	19	MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-6545;Reactome: R-HSA-380270;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7205;Reactome: R-HSA-380320;MetaCyc: PWY-7210	"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_054745380.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519	"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression"
XP_054725872.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis"
XP_054735741.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054741591.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054730064.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_054728943.1	6	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_054747704.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054730998.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_054730453.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054739172.1	23	Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-4086398	"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway"
XP_054732061.1	5	Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
XP_054744939.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054727221.1	15	Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167246	"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript"
XP_054732099.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054736645.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054725570.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054738039.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054728016.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054745403.1	7	MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836	"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis"
XP_054725200.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054739443.1	16	Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-209543;Reactome: R-HSA-5602498;Reactome: R-HSA-975155;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-9020702;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-1236974;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-6811558	"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"p75NTR recruits signalling complexes";"MyD88 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Interleukin-1 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_054741654.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054747313.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962	"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex"
XP_054727385.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054729703.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-201722	"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex"
XP_054730329.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054744834.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation"
XP_054738682.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_054727731.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054738365.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054742576.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054726497.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054740174.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054726679.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054731642.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054740903.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054739721.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054725756.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054737225.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054733642.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054731096.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054736100.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054735953.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108	"RORA activates gene expression";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054735498.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054741464.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054737203.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054742931.1	31	MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-6282;MetaCyc: PWY-7388;MetaCyc: PWY-7663;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-6113;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-8049;Reactome: R-HSA-9029558	"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Superpathway of mycolate biosynthesis";"";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Pederin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_054734069.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054743209.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054743915.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054735769.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741579.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054725862.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_054734488.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27	"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Cysteine and methionine metabolism"
XP_054746410.1	3	Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_054745181.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054743464.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054726398.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054741209.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2"
XP_054734214.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054738796.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054743981.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_054739217.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_054726835.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054737315.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486	"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis"
XP_054728458.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054726305.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-7901	"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine"
XP_054730948.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade"
XP_054728612.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054732736.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054732812.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054732049.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054742360.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054738375.1	5	Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054739384.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism"
XP_054740455.1	14	Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254	"Respiratory electron transport";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)"
XP_054739958.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054736466.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_054740839.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054735359.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054734898.1	8	Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609	"Neutrophil degranulation";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III"
XP_054735015.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054725745.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054727794.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_054726975.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054726625.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054732178.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054725493.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054743273.1	20	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;KEGG: 04151+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Amino acids regulate mTORC1";"Human papillomavirus infection";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"PI3K-Akt signaling pathway"
XP_054745290.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054746766.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis"
XP_054733988.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_054740515.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054737992.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054734247.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054742584.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054740979.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054732670.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054727084.1	5	Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_054725430.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054733354.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism"
XP_054741619.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7606	"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Peroxisomal protein import";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_054742078.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387	"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Ion channel transport";"Photosynthesis";"Insulin receptor recycling"
XP_054743896.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054728870.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054736393.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054744098.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747388.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054739607.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054729769.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054735188.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054739244.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054738453.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756	"Carnitine metabolism";"TP53 Regulates Metabolic Genes";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation"
XP_054743534.1	3	MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7	"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_054742849.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_054747435.1	18	Reactome: R-HSA-1482839;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054730682.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054745204.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054732450.1	30	Reactome: R-HSA-198693;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-9634638;Reactome: R-HSA-6804758;Reactome: R-HSA-389513;Reactome: R-HSA-5628897;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-199418;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-8948751;Reactome: R-HSA-392451;Reactome: R-HSA-1358803;Reactome: R-HSA-111447;Reactome: R-HSA-9614399;Reactome: R-HSA-6804757;Reactome: R-HSA-6804759;Reactome: R-HSA-211163	"AKT phosphorylates targets in the nucleus";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"PIP3 activates AKT signaling";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Acetylation";"CTLA4 inhibitory signaling";"TP53 Regulates Metabolic Genes";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Negative regulation of the PI3K/AKT network";"Human papillomavirus infection";"RUNX2 regulates genes involved in cell migration";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN stability and activity";"G beta:gamma signalling through PI3Kgamma";"Downregulation of ERBB2:ERBB3 signaling";"Activation of BAD and translocation to mitochondria";"Regulation of localization of FOXO transcription factors";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Association with Co-factors";"AKT-mediated inactivation of FOXO1A"
XP_054742402.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054725327.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054736894.1	10	Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10	"PPARA activates gene expression";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies"
XP_054729498.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054747859.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism"
XP_054727700.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054736502.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_054741486.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054745647.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054726531.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054736353.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054730818.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054742114.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins"
XP_054737952.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054747900.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway"
XP_054738721.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054733483.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054744636.1	25	Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811436	"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Aggrephagy";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054727863.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054725453.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054725998.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054745250.1	18	KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00250+2.6.1.1	"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_054735202.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054729399.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054726189.1	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_054741631.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054745368.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_054738231.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054741762.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735572.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_054727754.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054736997.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_054746892.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740627.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_054738162.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis"
XP_054729612.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054735236.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054734249.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054732490.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_054740977.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_054734158.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727182.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Neutrophil degranulation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054739796.1	6	MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-6722	"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis"
XP_054741352.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054731300.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054733276.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_054735518.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_054727364.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_054739086.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054743845.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_054744602.1	9	Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476	"PLC beta mediated events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events"
XP_054733300.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054743352.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_054744058.1	25	Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-190861	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly"
XP_054731276.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054737277.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054739923.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054740885.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054742790.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054726260.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054742147.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054726984.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054732180.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054735357.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054730932.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation";"Clathrin-mediated endocytosis"
XP_054733970.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054739219.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_054729870.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054735612.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054729236.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054735458.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054738366.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054744278.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054727075.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054739064.1	3	Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220	"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins"
XP_054736782.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054731970.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_054736475.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054728888.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_054732047.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054726457.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054744151.1	6	MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_054740408.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121	"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI"
XP_054727940.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054746239.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054744826.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054731193.1	13	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"mTOR signaling pathway"
XP_054747370.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054727882.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054741644.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054729202.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054741783.1	42	Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-110328;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-110331;Reactome: R-HSA-5617472;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-912446;Reactome: R-HSA-5693565	"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"HCMV Late Events";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054728769.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054738607.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054729572.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616	"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054745585.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054731130.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_054741093.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054725513.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054728498.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054740666.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054744770.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054730906.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054726500.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054736696.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054725365.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054727442.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638	"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins"
XP_054739663.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054745995.1	1	Reactome: R-HSA-1169408	"ISG15 antiviral mechanism"
XP_054726306.1	12	MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-801;MetaCyc: PWY-7901	"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine"
XP_054730327.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054747750.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725254.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325	"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis"
XP_054737316.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054731711.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_054726836.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054742740.1	11	Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-5689880;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6804756	"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation"
XP_054732381.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-427413	"HATs acetylate histones";"NoRC negatively regulates rRNA expression"
XP_054732787.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616	"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication"
XP_054738818.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_054731008.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5913;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism"
XP_054744937.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_054734832.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_054725746.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054727173.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054736465.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054726651.1	11	Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_054733284.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054741600.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054732225.1	4	Reactome: R-HSA-71240;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-210991	"Tryptophan catabolism";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions"
XP_054740456.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054738037.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054735943.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054733008.1	7	MetaCyc: PWY-7805;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605	"(aminomethyl)phosphonate degradation";"Adenine salvage";"Purine salvage";"Glyphosate degradation III";"Neutrophil degranulation";"Purine metabolism";"Adenine and adenosine salvage II"
XP_054735160.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054726778.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_054731095.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_054734336.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054735349.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054737226.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054725755.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054730430.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054727719.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054743043.1	5	Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24	"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway"
XP_054747917.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054737812.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_054737049.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054731331.1	6	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)"
XP_054737071.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054740062.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054726594.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Synthesis of PA"
XP_054743916.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054726667.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054728448.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054743195.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_054738118.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054735901.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058;Reactome: R-HSA-6799198	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis"
XP_054743808.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054740083.1	20	KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-1268020;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-163765	"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Mitochondrial protein import";"Methylaspartate cycle";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"ChREBP activates metabolic gene expression"
XP_054737920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054746409.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_054735562.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741772.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054736947.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054745222.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054730183.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054737251.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054727873.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054743210.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054741437.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression"
XP_054734132.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054732440.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054731843.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054726626.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054730862.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054728725.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_054736587.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054735860.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054747871.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_054726976.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054734299.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054743411.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054731266.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725663.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054742954.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054726102.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-7411;Reactome: R-HSA-2426168;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;Reactome: R-HSA-9018519;MetaCyc: PWY-5667;Reactome: R-HSA-75109;Reactome: R-HSA-8931987	"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Activation of gene expression by SREBF (SREBP)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Estrogen-dependent gene expression";"CDP-diacylglycerol biosynthesis I";"Triglyceride biosynthesis";"RUNX1 regulates estrogen receptor mediated transcription"
XP_054745312.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054740310.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733266.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054733558.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-6798695;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_054734622.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107	"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_054743320.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-5628897	"Regulation of the apoptosome activity";"Formation of apoptosome";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes"
XP_054742388.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054729811.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_054727313.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_054743077.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054744095.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054741806.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054747807.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_054726693.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054730467.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_054744227.1	4	Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874	"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I"
XP_054741077.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054738116.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-204005	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPII-mediated vesicle transport"
XP_054731911.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054742882.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054730671.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054738995.1	4	Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism"
XP_054743806.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054727704.1	2	Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054745376.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_054745037.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054736890.1	23	Reactome: R-HSA-432040;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-6814122	"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G-protein activation";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054730250.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747221.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054737599.1	7	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054735743.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054744472.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054734043.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054736325.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_054726044.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054739659.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_054732454.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2644606	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054741593.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054727223.1	15	Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6796648	"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054728979.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054732063.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054747420.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_054730451.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054742492.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054740870.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_054745294.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054726978.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054744711.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054728629.1	17	Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-445989;Reactome: R-HSA-1169091;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway"
XP_054745401.1	7	MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836	"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis"
XP_054726628.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054739748.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054727080.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054731937.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_054744008.1	4	KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250	"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_054743528.1	3	MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403	"5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_054728874.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054742386.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054744652.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054729701.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1912408	"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation"
XP_054742075.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054731268.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727733.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054729837.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054737557.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054741302.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7574;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-5136	"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_054731985.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_054738060.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054730758.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054734001.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_054743261.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054726838.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054742182.1	4	Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_054732639.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_054735701.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054725479.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_054727681.1	4	Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922	"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis"
XP_054730511.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054731521.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis"
XP_054732792.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054736698.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054741261.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_054726308.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054728455.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054738699.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054738477.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054730945.1	7	Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381070	"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones"
XP_054740751.1	10	Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-400206	"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha"
XP_054742255.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054726407.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054740612.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054732082.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054726017.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054737230.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054741972.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054731006.1	13	KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-561	"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_054736190.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054745610.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_054741622.1	20	MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-6920	"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)"
XP_054747256.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054747568.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_054741257.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_054738657.1	16	Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167152	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_054732129.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054734338.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27	"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Cysteine and methionine metabolism"
XP_054737228.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054728675.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_054737431.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054745172.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_054736104.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054727114.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054735495.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054743257.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727847.1	12	Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736	"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors"
XP_054739013.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_054737372.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054734808.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054731032.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054727529.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054743918.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054738706.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054745443.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054743132.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_054726820.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054728446.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054741918.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054732514.1	5	Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_054746965.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054736648.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054738649.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054746040.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-983231	"Prolactin receptor signaling";"Signaling by Leptin";"Growth hormone receptor signaling";"Factors involved in megakaryocyte development and platelet production"
XP_054745327.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054738671.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-110314	"Neddylation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Recognition of DNA damage by PCNA-containing replication complex"
XP_054739539.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054736035.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_054747700.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_054725469.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_054731126.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054725491.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054733602.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054743650.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054734845.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054725798.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054737611.1	57	Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168	"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054740406.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054742374.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054729238.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731867.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_054741962.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054735456.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726601.1	5	Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614	"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_054736391.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054727954.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation"
XP_054747027.1	7	KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3	"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate"
XP_054740432.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054737362.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054726766.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_054742109.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054747208.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_054740371.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_054744828.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054745384.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_054746975.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054736759.1	13	Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52	"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_054729730.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs"
XP_054737184.1	24	Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-190861	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly"
XP_054745493.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054739723.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736	"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors"
XP_054740901.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054729676.1	9	Reactome: R-HSA-9656256;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255	"Defective OGG1 Substrate Processing";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding"
XP_054727159.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054744638.1	6	MetaCyc: PWY-6908;MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-7356;MetaCyc: PWY-6898	"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage IV (yeast)";"Thiamine salvage III"
XP_054747066.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054729926.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_054739290.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_054733826.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_054738511.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054743067.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054730816.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054739705.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_054743389.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-432142;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Platelet sensitization by LDL";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Chylomicron remodeling";"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_054744130.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054737201.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054738426.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054725996.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054743543.1	5	MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_054737549.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054725115.1	11	MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054737571.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_054745366.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_054742719.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054743983.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737989.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_054727740.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054744128.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054730657.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054726968.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054726410.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054735421.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054727197.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054741983.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"HDR through MMEJ (alt-NHEJ)";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054726000.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054726285.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054738070.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054727565.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054730312.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_054744056.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-2173788;MetaCyc: PWY-7511	"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling";"Protein ubiquitination"
XP_054731322.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans"
XP_054728864.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054739088.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_054726152.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_054742173.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054740703.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054737454.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_054746499.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_054738539.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054739671.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054746927.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054726054.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054739649.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054739467.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054735753.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054725537.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054727370.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054731986.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_054727576.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453	"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis"
XP_054743324.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054733986.1	3	KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism"
XP_054742662.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054727206.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Clathrin-mediated endocytosis"
XP_054727161.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054741324.1	10	Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23	"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"HS-GAG degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series"
XP_054741898.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8964038	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance"
XP_054738996.1	4	KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558;MetaCyc: PWY-5331	"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine";"Taurine biosynthesis I"
XP_054728220.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054743387.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054726192.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054731191.1	13	KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;Reactome: R-HSA-416482	"PI3K-Akt signaling pathway";"Thermogenesis";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events"
XP_054743805.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054731340.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054727232.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054728793.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_054746889.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054744096.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054747386.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054730748.1	10	MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5849;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163	"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_054742311.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054737547.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054747163.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_054741091.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054740224.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054734464.1	9	MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8	"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_054736326.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_054737829.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054726463.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054741488.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883	"Neutrophil degranulation";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG"
XP_054728951.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054728730.1	10	MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_054737063.1	9	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68867	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex"
XP_054734209.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054743069.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis"
XP_054736757.1	13	Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902	"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)"
XP_054736351.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437	"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation"
XP_054726533.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054728062.1	3	KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_054735496.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054736122.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_054731481.1	14	Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665	"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells"
XP_054737082.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_054725758.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054738723.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_054735164.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054746966.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054727861.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054745219.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054741633.1	12	KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817	"Purine metabolism";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis"
XP_054727899.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054726396.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_054730380.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054728445.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054729969.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_054728456.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054730946.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381042	"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression"
XP_054733891.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054742744.1	19	KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7606;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726	"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)"
XP_054732738.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054738798.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Neutrophil degranulation";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_054731869.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054726504.1	22	Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877	"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase"
XP_054730403.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054733023.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054743105.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_054739956.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054741247.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702	"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling"
XP_054745329.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054738574.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054738647.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054744988.1	4	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_054739537.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054741604.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054734525.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054737129.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054725671.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_054731635.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348	"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex"
XP_054735174.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054727527.1	9	MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;Reactome: R-HSA-70263	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis"
XP_054743034.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_054728666.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination"
XP_054739116.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054740081.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7659;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-6383	"Geranyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_054727944.1	4	Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160	"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_054733635.1	5	Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88	"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism"
XP_054744598.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054726765.1	14	Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-75955	"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation"
XP_054738659.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054732127.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones"
XP_054732243.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741259.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_054744774.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740397.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_054736412.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054736658.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054735675.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726540.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_054731134.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_054725657.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054742512.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727871.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054746976.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054737742.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054728018.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054731125.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_054732184.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054736036.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_054726980.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054736749.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054731841.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054741413.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054725378.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-5683826	"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Surfactant metabolism"
XP_054747873.1	5	Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation"
XP_054731974.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054742578.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_054725661.1	1	Reactome: R-HSA-480985	"Synthesis of dolichyl-phosphate-glucose"
XP_054728837.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725477.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_054743297.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-5689880	"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"Ub-specific processing proteases"
XP_054728701.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054744505.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054729874.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054740405.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_054733974.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054735839.1	4	KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14	"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism"
XP_054738479.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054732362.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054739477.1	17	Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-2467813;Reactome: R-HSA-174048	"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_054731939.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054737559.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054729839.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054746471.1	4	KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate"
XP_054732383.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054746802.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_054735874.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054736907.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054733304.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054734654.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054728977.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054735629.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727171.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054731834.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054735941.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054744055.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054742066.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054729934.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_054730233.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation"
XP_054739378.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054733179.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054745039.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054728252.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054729925.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054737597.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_054747065.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054732884.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_054731179.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733596.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054742110.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054739657.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054728684.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054737073.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054746500.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_054743079.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054725116.1	11	MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054745682.1	7	Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352	"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis"
XP_054747442.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_054743041.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_054738425.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation"
XP_054747809.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054727750.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054746270.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054732400.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054726473.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054741079.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054730574.1	18	MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_054730647.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054731803.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054734474.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_054730491.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054730835.1	10	KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7198;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7210;MetaCyc: PWY-3841;MetaCyc: PWY-7187;MetaCyc: PWY-7184	"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054745355.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727760.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054728971.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation"
XP_054745264.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727177.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism"
XP_054728949.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054733704.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054730887.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054730305.1	10	MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_054742130.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054740840.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054727545.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054739332.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054746477.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054735119.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_054732783.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_054731298.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815	"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D"
XP_054747055.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054744990.1	6	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes"
XP_054733313.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054732644.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054746816.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739594.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_054727911.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054728117.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_054747319.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054742638.1	11	MetaCyc: PWY-7456;MetaCyc: PWY-3881;MetaCyc: PWY-882;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-5659;Reactome: R-HSA-446205	"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose"
XP_054730323.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054731080.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054733575.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054739500.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054731205.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054741047.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054730679.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054730497.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex"
XP_054747913.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054743047.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054727556.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054731575.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054733080.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling"
XP_054743688.1	3	Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60	"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation"
XP_054730929.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation"
XP_054742620.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054727985.1	1	Reactome: R-HSA-376172	"DSCAM interactions"
XP_054729465.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_054733147.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054730398.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054742128.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054733814.1	5	MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_054741582.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_054728038.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_054740140.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054742830.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_054737342.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054727877.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_054740797.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054740391.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054742506.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054739976.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_054743433.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_054727416.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054730040.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054747774.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740087.1	20	MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5172;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403	"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Mitochondrial protein import";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)"
XP_054730634.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_054726682.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054740648.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_054727521.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471	"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_054734253.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054742021.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054743490.1	57	Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603	"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"UCH proteinases"
XP_054725836.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_054740035.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054728301.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054738447.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054740759.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054728283.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054736668.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054747523.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054741404.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_054730519.1	4	Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054727689.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_054725778.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_054728656.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_054742483.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054741942.1	5	MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556	"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes"
XP_054744296.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_054729524.1	10	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239	"Thermogenesis";"Human immunodeficiency virus 1 infection";"RSK activation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1"
XP_054726755.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054736371.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_054738459.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054740747.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054740341.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054740379.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054737534.1	83	Reactome: R-HSA-1250347;Reactome: R-HSA-9028731;Reactome: R-HSA-2029482;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-983695;Reactome: R-HSA-8853334;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-2871796;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-8853338;Reactome: R-HSA-5654732;Reactome: R-HSA-2424491;Reactome: R-HSA-8983432;Reactome: R-HSA-9034864;Reactome: R-HSA-2179392;Reactome: R-HSA-9634285;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640;Reactome: R-HSA-2428933;Reactome: R-HSA-8875555;Reactome: R-HSA-1250196;Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-375165;Reactome: R-HSA-182971;Reactome: R-HSA-9607240;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-8856825;Reactome: R-HSA-5654720;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-5654699;Reactome: R-HSA-1433559;Reactome: R-HSA-1963642;Reactome: R-HSA-8856828;Reactome: R-HSA-5654704;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-186763;Reactome: R-HSA-74749;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-5654726;Reactome: R-HSA-2871809;Reactome: R-HSA-6807004;Reactome: R-HSA-9026519;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-1839117;Reactome: R-HSA-5655253;Reactome: R-HSA-9664565;Reactome: R-HSA-5654727;Reactome: R-HSA-912631;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-8851805;Reactome: R-HSA-391160;Reactome: R-HSA-8875360;Reactome: R-HSA-5655291;Reactome: R-HSA-5654719;Reactome: R-HSA-8875656;Reactome: R-HSA-1257604;Reactome: R-HSA-389359;Reactome: R-HSA-2730905	"SHC1 events in ERBB4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of actin dynamics for phagocytic cup formation";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PI3K Cascade";"Signalling to RAS";"STAT5 Activation";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"FCERI mediated MAPK activation";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR3 signaling";"DAP12 signaling";"Interleukin-15 signaling";"Activated NTRK3 signals through RAS";"EGFR Transactivation by Gastrin";"Constitutive Signaling by Overexpressed ERBB2";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling";"SHC-related events triggered by IGF1R";"MET activates RAP1 and RAC1";"SHC1 events in ERBB2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"NCAM signaling for neurite out-growth";"EGFR downregulation";"FLT3 Signaling";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR4";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"SHC-mediated cascade:FGFR2";"Regulation of KIT signaling";"PI3K events in ERBB2 signaling";"Clathrin-mediated endocytosis";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Downstream signal transduction";"Signal attenuation";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"Negative regulation of FGFR1 signaling";"FCERI mediated Ca+2 mobilization";"Negative regulation of MET activity";"Activated NTRK2 signals through RAS";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR2 in disease";"Signaling by ERBB2 KD Mutants";"Negative regulation of FGFR2 signaling";"Regulation of signaling by CBL";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling";"MET activates PTPN11";"PI-3K cascade:FGFR1";"MET activates RAS signaling";"Signal regulatory protein family interactions";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR4 in disease";"SHC-mediated cascade:FGFR4";"MET receptor recycling";"PIP3 activates AKT signaling";"CD28 dependent Vav1 pathway";"Role of LAT2/NTAL/LAB on calcium mobilization"
XP_054746426.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030	"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA"
XP_054739022.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_054725457.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054740190.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054727867.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054735475.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_054727602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054727058.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-170670	"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway"
XP_054744255.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-3214847	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones"
XP_054747853.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054729959.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054731435.1	6	MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_054745463.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054733859.1	11	MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Methylaspartate cycle"
XP_054725260.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054735092.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054738323.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_054725358.1	1	Reactome: R-HSA-196836	"Vitamin C (ascorbate) metabolism"
XP_054728194.1	7	Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-69473	"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint"
XP_054739517.1	10	MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_054733435.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054732411.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_054725984.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation"
XP_054731487.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054741440.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_054726513.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054736928.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054730004.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054739531.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054734514.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054737273.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_054743279.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054731424.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054732772.1	12	Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167243	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery"
XP_054740605.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054744029.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_054738641.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054738497.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation termination"
XP_054738679.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054730288.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_054725927.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054736361.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054726609.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_054744246.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054739189.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955	"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation"
XP_054731897.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054741992.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_054728608.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054736399.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054741613.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054737619.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054725768.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_054736170.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054743992.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_054742801.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453	"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis"
XP_054746368.1	19	MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086	"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_054728999.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_054730554.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054735429.1	4	KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_054738135.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054728961.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_054727770.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054740714.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054735997.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054737053.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_054726329.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054746921.1	5	KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Purine metabolism"
XP_054744940.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054739499.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054732567.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_054743234.1	19	MetaCyc: PWY-1622;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;KEGG: 00620+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7115;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7383	"Formaldehyde assimilation I (serine pathway)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Methane metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_054742227.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054740833.1	3	Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766	"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown"
XP_054735353.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054725531.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_054727595.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_054742095.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_054728710.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_054738040.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054739927.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_054738634.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054740281.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_054741234.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054747642.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054734924.1	11	Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692	"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR"
XP_054739260.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054740909.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054742418.1	11	KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-6549;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00220+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2	"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Arginine biosynthesis";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism"
XP_054742960.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054728800.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054727508.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054727151.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054743225.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054730447.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054740480.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054734674.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054730348.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054735854.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054728393.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054737464.1	17	Reactome: R-HSA-167246;Reactome: R-HSA-75955;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-113418	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex"
XP_054731740.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054734829.1	17	Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054742711.1	182	Reactome: R-HSA-975957;Reactome: R-HSA-5654732;Reactome: R-HSA-2565942;Reactome: R-HSA-937039;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-6804757;Reactome: R-HSA-110312;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-174048;Reactome: R-HSA-9645460;Reactome: R-HSA-9613829;Reactome: R-HSA-3785653;Reactome: R-HSA-5656169;Reactome: R-HSA-1799339;Reactome: R-HSA-8866652;Reactome: R-HSA-8951664;Reactome: R-HSA-3322077;Reactome: R-HSA-156827;Reactome: R-HSA-9013973;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-937041;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-110314;Reactome: R-HSA-901032;Reactome: R-HSA-8948747;Reactome: R-HSA-5654726;Reactome: R-HSA-937042;Reactome: R-HSA-6783310;Reactome: R-HSA-174113;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-72764;Reactome: R-HSA-168927;Reactome: R-HSA-8856828;Reactome: R-HSA-2672351;Reactome: R-HSA-2559585;Reactome: R-HSA-8876493;Reactome: R-HSA-211733;Reactome: R-HSA-2173796;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-9646399;Reactome: R-HSA-2408557;Reactome: R-HSA-912631;Reactome: R-HSA-1234176;Reactome: R-HSA-209560;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-532668;Reactome: R-HSA-2691232;Reactome: R-HSA-2559580;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-72702;Reactome: R-HSA-5689603;Reactome: R-HSA-450302;Reactome: R-HSA-180585;Reactome: R-HSA-2122947;Reactome: R-HSA-5696395;Reactome: R-HSA-8948751;Reactome: R-HSA-445989;Reactome: R-HSA-5357905;Reactome: R-HSA-5675221;Reactome: R-HSA-917937;Reactome: R-HSA-5358346;Reactome: R-HSA-2122948;Reactome: R-HSA-72649;Reactome: R-HSA-1236382;Reactome: R-HSA-69541;Reactome: R-HSA-9633012;Reactome: R-HSA-8866654;Reactome: R-HSA-6804760;Reactome: R-HSA-6781827;Reactome: R-HSA-69481;Reactome: R-HSA-977225;Reactome: R-HSA-69231;Reactome: R-HSA-450408;Reactome: R-HSA-2173795;Reactome: R-HSA-6782135;Reactome: R-HSA-2894862;Reactome: R-HSA-192823;Reactome: R-HSA-1236974;Reactome: R-HSA-936964;Reactome: R-HSA-5687128;Reactome: R-HSA-9033241;Reactome: R-HSA-187577;Reactome: R-HSA-5678895;Reactome: R-HSA-8849469;Reactome: R-HSA-9637628;Reactome: R-HSA-168638;Reactome: R-HSA-5654733;Reactome: R-HSA-6804756;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5689877;Reactome: R-HSA-4641258;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-72689;Reactome: R-HSA-9615710;Reactome: R-HSA-182971;Reactome: R-HSA-5676590;Reactome: R-HSA-937072;Reactome: R-HSA-175474;Reactome: R-HSA-5205685;Reactome: R-HSA-450321;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5654727;Reactome: R-HSA-156902;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-201681;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-8875360;Reactome: R-HSA-69017;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-209543;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-917729;Reactome: R-HSA-1358803;Reactome: R-HSA-5693565;Reactome: R-HSA-5632684;Reactome: R-HSA-179409;Reactome: R-HSA-2979096;Reactome: R-HSA-5689896;Reactome: R-HSA-5658442;Reactome: R-HSA-5689901;Reactome: R-HSA-2173791;Reactome: R-HSA-5357956;Reactome: R-HSA-8863795;Reactome: R-HSA-975163;Reactome: R-HSA-5610780;Reactome: R-HSA-349425;Reactome: R-HSA-5685942;Reactome: R-HSA-174490;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-1169408;Reactome: R-HSA-68827;Reactome: R-HSA-5655862;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-382556;Reactome: R-HSA-9014325;Reactome: R-HSA-4641263;Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-3134975;Reactome: R-HSA-3769402;Reactome: R-HSA-5610783;Reactome: R-HSA-168928;Reactome: R-HSA-975144;Reactome: R-HSA-2644606;Reactome: R-HSA-174084;Reactome: R-HSA-5696394;Reactome: R-HSA-975110;Reactome: R-HSA-75815;Reactome: R-HSA-5684264;Reactome: R-HSA-5696400;Reactome: R-HSA-72706;Reactome: R-HSA-162588;Reactome: R-HSA-69601;Reactome: R-HSA-2559582;Reactome: R-HSA-6781823	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Negative regulation of FGFR3 signaling";"Regulation of PLK1 Activity at G2/M Transition";"IRAK1 recruits IKK complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Regulation of TP53 Degradation";"Translesion synthesis by REV1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"APC/C:Cdc20 mediated degradation of Cyclin B";"Alpha-protein kinase 1 signaling pathway";"Chaperone Mediated Autophagy";"Myoclonic epilepsy of Lafora";"Termination of translesion DNA synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Neddylation";"Glycogen synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"TICAM1-dependent activation of IRF3/IRF7";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IKK complex recruitment mediated by RIP1";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Recognition of DNA damage by PCNA-containing replication complex";"ER Quality Control Compartment (ERQC)";"Regulation of PTEN localization";"Negative regulation of FGFR1 signaling";"IRAK2 mediated activation of TAK1 complex";"Fanconi Anemia Pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"Eukaryotic Translation Termination";"TICAM1, RIP1-mediated IKK complex recruitment";"Clathrin-mediated endocytosis";"Stimuli-sensing channels";"Oncogene Induced Senescence";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Aggrephagy";"Selenocysteine synthesis";"Regulation of signaling by CBL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NF-kB is activated and signals survival";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Oxidative Stress Induced Senescence";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"Ribosomal scanning and start codon recognition";"UCH proteinases";"activated TAK1 mediates p38 MAPK activation";"Vif-mediated degradation of APOBEC3G";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of Incision Complex in GG-NER";"Regulation of PTEN stability and activity";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of TNFR1 signaling";"Negative regulation of MAPK pathway";"Iron uptake and transport";"Hedgehog ligand biogenesis";"Activated NOTCH1 Transmits Signal to the Nucleus";"Translation initiation complex formation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Stabilization of p53";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"E3 ubiquitin ligases ubiquitinate target proteins";"Regulation of TP53 Activity through Methylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"G2/M Checkpoints";"Amyloid fiber formation";"Cyclin D associated events in G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Dual incision in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Viral mRNA Translation";"ER-Phagosome pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MAPK6/MAPK4 signaling";"Peroxisomal protein import";"SCF(Skp2)-mediated degradation of p27/p21";"Defective CFTR causes cystic fibrosis";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Modulation by Mtb of host immune system";"NOD1/2 Signaling Pathway";"Negative regulation of FGFR4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Josephin domain DUBs";"Degradation of DVL";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Formation of a pool of free 40S subunits";"Late endosomal microautophagy";"EGFR downregulation";"NIK-->noncanonical NF-kB signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Assembly Of The HIV Virion";"Pink/Parkin Mediated Mitophagy";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Negative regulation of FGFR2 signaling";"Peptide chain elongation";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"TCF dependent signaling in response to WNT";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"CDK-mediated phosphorylation and removal of Cdc6";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"p75NTR recruits signalling complexes";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of ERBB2:ERBB3 signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hedgehog 'on' state";"APC-Cdc20 mediated degradation of Nek2A";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Ovarian tumor domain proteases";"Regulation of RAS by GAPs";"Metalloprotease DUBs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TNFR1-induced NFkappaB signaling pathway";"Downregulation of ERBB2 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of GLI1 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Homologous Recombination (HRR)";"Membrane binding and targetting of GAG proteins";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"ISG15 antiviral mechanism";"CDT1 association with the CDC6:ORC:origin complex";"Translesion synthesis by POLK";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"ABC-family proteins mediated transport";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of FZD by ubiquitination";"Ub-specific processing proteases";"Negative regulation of MET activity";"Regulation of innate immune responses to cytosolic DNA";"Deactivation of the beta-catenin transactivating complex";"Degradation of GLI2 by the proteasome";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Autodegradation of Cdh1 by Cdh1:APC/C";"DNA Damage Recognition in GG-NER";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ubiquitin-dependent degradation of Cyclin D";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dual Incision in GG-NER";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Budding and maturation of HIV virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of TC-NER Pre-Incision Complex"
XP_054737579.1	8	MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6372;MetaCyc: PWY-6664;Reactome: R-HSA-1855183	"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054738603.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054726064.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741573.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054735763.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054729475.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054726217.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-5696394;Reactome: R-HSA-171319;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER";"Telomere Extension By Telomerase";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases"
XP_054733199.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_054727555.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054739835.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054735484.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Neutrophil degranulation"
XP_054737577.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_054733161.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054744066.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054733206.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054744672.1	20	MetaCyc: PWY-7574;MetaCyc: PWY-735;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7854;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6	"Propanoyl-coa degradation II";"Jasmonic acid biosynthesis";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(5Z)-dodecenoate biosynthesis II";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation"
XP_054738022.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054735218.1	2	Reactome: R-HSA-8983711;Reactome: R-HSA-909733	"OAS antiviral response";"Interferon alpha/beta signaling"
XP_054726162.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054732654.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054730332.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054734201.1	3	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_054734166.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054726493.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054740907.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_054730471.1	14	MetaCyc: PWY-3841;MetaCyc: PWY-3661-1;MetaCyc: PWY-3661;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+2.1.2.1;Reactome: R-HSA-196757;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-181	"Folate transformations II (plants)";"Glycine betaine degradation II (mammalian)";"Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Metabolism of folate and pterines";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Folate transformations I";"Photorespiration "
XP_054737145.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_054734494.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054725625.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_054728959.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054739679.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054735710.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation"
XP_054739641.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054726721.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054730306.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054740552.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054735502.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054738531.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054735894.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_054730270.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054733157.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PA";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054745356.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727191.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_054733232.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_054746815.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054746798.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054747056.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726231.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054728429.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054727340.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_054735999.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054729608.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_054738189.1	6	KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054736188.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054727546.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054726607.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_054728154.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054747021.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054736397.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054726244.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_054725398.1	4	Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_054725824.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054734752.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745285.1	44	Reactome: R-HSA-2559580;Reactome: R-HSA-202670;Reactome: R-HSA-444257;Reactome: R-HSA-879415;Reactome: R-HSA-5654733;Reactome: R-HSA-6802955;KEGG: 04150+2.7.11.24;Reactome: R-HSA-112409;Reactome: R-HSA-162658;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-5673001;Reactome: R-HSA-8943724;Reactome: R-HSA-6811558;Reactome: R-HSA-2871796;Reactome: R-HSA-9649948;Reactome: R-HSA-375165;Reactome: R-HSA-9634638;Reactome: R-HSA-450341;Reactome: R-HSA-170968;Reactome: R-HSA-9627069;Reactome: R-HSA-9635465;Reactome: R-HSA-74749;Reactome: R-HSA-881907;Reactome: R-HSA-3371453;Reactome: R-HSA-198753;Reactome: R-HSA-5663213;Reactome: R-HSA-5654727;Reactome: R-HSA-456926;Reactome: R-HSA-5674499;Reactome: R-HSA-5675221;Reactome: R-HSA-5654726;Reactome: R-HSA-8939211;Reactome: R-HSA-445144;Reactome: R-HSA-6802946;Reactome: R-HSA-2559582;Reactome: R-HSA-1295596;Reactome: R-HSA-8940973;Reactome: R-HSA-2559585;Reactome: R-HSA-982772;Reactome: R-HSA-5668599	"Oxidative Stress Induced Senescence";"ERKs are inactivated";"RSK activation";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR4 signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"mTOR signaling pathway";"RAF-independent MAPK1/3 activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"RAF/MAP kinase cascade";"Regulation of PTEN gene transcription";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"FCERI mediated MAPK activation";"Signaling downstream of RAS mutants";"NCAM signaling for neurite out-growth";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Activation of the AP-1 family of transcription factors";"Frs2-mediated activation";"Regulation of the apoptosome activity";"Suppression of apoptosis";"Signal attenuation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of HSF1-mediated heat shock response";"ERK/MAPK targets";"RHO GTPases Activate WASPs and WAVEs";"Negative regulation of FGFR2 signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative feedback regulation of MAPK pathway";"Negative regulation of MAPK pathway";"Negative regulation of FGFR1 signaling";"ESR-mediated signaling";"Signal transduction by L1";"Signaling by moderate kinase activity BRAF mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Spry regulation of FGF signaling";"RUNX2 regulates osteoblast differentiation";"Oncogene Induced Senescence";"Growth hormone receptor signaling";"RHO GTPases Activate NADPH Oxidases"
XP_054731616.1	22	Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340	"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex"
XP_054737352.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054739634.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_054731994.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054725679.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_054725497.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_054745152.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054732855.1	9	Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475	"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054738461.1	6	KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)"
XP_054725929.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054743507.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054745727.1	6	MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_054744027.1	16	KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-5723	"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Rubisco shunt"
XP_054741277.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054738984.1	4	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_054734362.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054733857.1	11	MetaCyc: PWY-7254;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-7268;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7124	"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)"
XP_054732846.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054729957.1	16	Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942	"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)"
XP_054742505.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054729536.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054738260.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054739625.1	5	KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis"
XP_054739519.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6554	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)"
XP_054747828.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_054726745.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054741660.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_054740478.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT"
XP_054727964.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054725835.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054728475.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054740749.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-427413	"MECP2 regulates neuronal receptors and channels";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression"
XP_054738889.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054742523.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054732263.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054729218.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_054727869.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054725459.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_054729393.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054725348.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_054733402.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_054730022.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054737001.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054740606.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054733012.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_054730966.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054729971.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054735656.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054745628.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054741450.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054744107.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497	"Estrogen-dependent gene expression";"ESR-mediated signaling";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054746380.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054736779.1	11	Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237	"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2"
XP_054746955.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054731871.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054726011.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054729621.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_054738802.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054740122.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054743938.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_054729844.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054738667.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054732392.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054734230.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054738594.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis"
XP_054740757.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054727048.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054730517.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054734417.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054742265.1	15	Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-1433557	"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT"
XP_054740089.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054744256.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_054740910.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054727103.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054737338.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_054742988.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054743920.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054728042.1	27	Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910	"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs"
XP_054738306.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054746425.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-3108214;Reactome: R-HSA-110328	"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_054739288.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054739965.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580	"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence"
XP_054737772.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054737210.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054727841.1	12	Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"RAF/MAP kinase cascade";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054743178.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054732273.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054741251.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054740799.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633	"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054745630.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054731436.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054731149.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054735343.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_054738976.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054739554.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis"
XP_054747227.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054731258.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054747143.1	9	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9620244	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation"
XP_054733149.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054735589.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054726443.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_054731917.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054732053.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_054741736.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727939.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_054747737.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_054730677.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725965.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054734176.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054743812.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-975634;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409	"Anandamide biosynthesis I";"Retinoid metabolism and transport";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_054727713.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054736235.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-5466	"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis"
XP_054725288.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054747801.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis"
XP_054735117.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054737551.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_054736224.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_054730358.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054732196.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_054741702.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054731750.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054740326.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054728119.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_054725090.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054747711.1	13	MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-6613	"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate polyglutamylation";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_054745308.1	4	Reactome: R-HSA-156581;MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6	"Methylation";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism"
XP_054732579.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054738136.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054731931.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_054732541.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054727803.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054743702.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054745522.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054729707.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-3899300;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907	"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Circadian Clock";"TRAF6 mediated IRF7 activation";"SUMOylation of transcription cofactors";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_054728524.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054725780.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_054744311.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054745407.1	7	MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80	"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism"
XP_054742096.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_054747418.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054747652.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054743878.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_054730457.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_054729656.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054747284.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339	"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane"
XP_054736734.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_054743754.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054740409.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054743029.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054742460.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054740842.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054729124.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054728457.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054735835.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054745840.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054737891.1	6	MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;MetaCyc: PWY-622	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis"
XP_054744241.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054736183.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054736560.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis"
XP_054743863.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
XP_054735459.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054739218.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_054740264.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054729603.1	3	Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646	"Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification"
XP_054738646.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054744613.1	9	Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206	"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_054744992.1	6	KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403	"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)"
XP_054725194.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054739957.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054730119.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054739800.1	8	Reactome: R-HSA-6791461;MetaCyc: PWY-5723;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-1861	"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054728984.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054742257.1	2	KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259	"Purine metabolism";"Purine catabolism"
XP_054735323.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_054729625.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_054726015.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054739536.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054728260.1	11	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway"
XP_054746951.1	7	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054731875.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054747690.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054733082.1	17	MetaCyc: PWY-6609;MetaCyc: PWY-4202;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1	"Adenine and adenosine salvage III";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine salvage";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II"
XP_054741364.1	5	MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26	"Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism"
XP_054729040.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054739272.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054735497.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054739710.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054743255.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727845.1	12	Reactome: R-HSA-447038;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_054734388.1	2	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054736756.1	13	MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_054743364.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-202733;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901	"Chylomicron assembly";"Scavenging by Class H Receptors";"Cell surface interactions at the vascular wall";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Scavenging by Class B Receptors";"Chylomicron clearance";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"VLDL assembly";"Scavenging by Class F Receptors";"Chylomicron remodeling"
XP_054728544.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054731082.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054726081.1	16	Reactome: R-HSA-167590;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-8866427	"Nef Mediated CD4 Down-regulation";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation"
XP_054728499.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054739502.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054726498.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054738154.1	13	MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182	"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I"
XP_054746967.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054747198.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054739999.1	9	KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II"
XP_054737788.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_054736244.1	10	MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism"
XP_054733674.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_054736883.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054738997.1	4	KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine"
XP_054742832.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054735135.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054737546.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054741580.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054729398.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054729824.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054725961.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726188.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054747805.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_054747387.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_054744097.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054736231.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1"
XP_054737340.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054725999.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054735634.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054733063.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054729641.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones"
XP_054736327.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_054735040.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054743492.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663	"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_054745035.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054747214.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_054728531.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054730042.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER"
XP_054726680.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054729929.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_054745024.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5856	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)"
XP_054725800.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_054740286.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837	"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation"
XP_054735625.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054725536.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054746062.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling"
XP_054739466.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054733454.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054725330.1	3	KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1	"Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis"
XP_054746926.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_054729323.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054727821.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_054732760.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054742077.1	8	Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Ion channel transport";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Photosynthesis";"Insulin receptor recycling"
XP_054738763.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054734159.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054727577.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166	"Anandamide biosynthesis II";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA"
XP_054727644.1	18	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI"
XP_054741882.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054740653.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054734248.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054743882.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054733987.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054737596.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_054740192.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054741904.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054745379.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128	"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling"
XP_054732508.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054745341.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054733597.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054746408.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_054725621.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_054737141.1	7	MetaCyc: PWY-5921;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539	"Glutaminyl-trnagln biosynthesis via transamidation";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism"
XP_054746885.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054726224.1	6	Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253	"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Circadian Clock"
XP_054743339.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_054731073.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054725117.1	11	MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_054740463.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054734223.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054727551.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054737333.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054729669.1	7	Reactome: R-HSA-1483226;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351	"Synthesis of PI";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_054746837.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054741339.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054738119.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_054735090.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054731165.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_054745133.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054739283.1	7	Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561	"Synthesis of PG";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III"
XP_054735414.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-5689877;Reactome: R-HSA-983168;Reactome: R-HSA-977225	"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Josephin domain DUBs";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation"
XP_054734704.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054739144.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054735288.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054728102.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054745605.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_054727043.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054735965.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis"
XP_054742543.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054729554.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259	"Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism"
XP_054734298.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054732595.1	7	MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586	"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_054736172.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054743990.1	5	Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24	"p38MAPK events";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"mTOR signaling pathway"
XP_054727694.1	2	Reactome: R-HSA-201681;Reactome: R-HSA-3772470	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists"
XP_054745623.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054738535.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054738773.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054737841.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054736037.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_054727772.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054744269.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741873.1	42	Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-171306;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-110329;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-5334118;Reactome: R-HSA-8939236;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-73772	"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged pyrimidine";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"HCMV Early Events";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"DNA methylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_054738465.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_054730997.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_054740892.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054731009.1	13	KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384	"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_054739589.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054729004.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054728270.1	9	Reactome: R-HSA-156590;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18	"Glutathione conjugation";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Drug metabolism - cytochrome P450"
XP_054731865.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins"
XP_054725476.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_054730353.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_054738819.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_054746137.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054728836.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054737974.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054747025.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054728500.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054739131.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054725817.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054729965.1	5	MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism"
XP_054744942.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054742962.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054732867.1	18	MetaCyc: PWY-6803;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409	"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_054743374.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054728802.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054744582.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054735691.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-6782135	"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"mRNA Capping";"Dual incision in TC-NER"
XP_054747640.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054729090.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054725283.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-913709;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins";"N-Glycan antennae elongation"
XP_054739262.1	4	Reactome: R-HSA-4755583;Reactome: R-HSA-446199;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129	"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_054727718.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054737048.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054742501.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054745334.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054731742.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054726741.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054736872.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054746977.1	19	MetaCyc: PWY-7221;MetaCyc: PWY-7184;Reactome: R-HSA-380270;MetaCyc: PWY-7226;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-6545;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7222	"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_054725656.1	10	Reactome: R-HSA-5419276;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054737134.1	17	MetaCyc: PWY-5789;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-4381;MetaCyc: PWY-6722;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-200425	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Carnitine metabolism"
XP_054738020.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-166208	"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"mTORC1-mediated signalling"
XP_054739947.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition"
XP_054726432.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054733372.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054742604.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054731372.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054739524.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_054746979.1	12	MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5132	"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Propanoate metabolism";"Lupulone and humulone biosynthesis"
XP_054736755.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054726371.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054727846.1	12	Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_054743256.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054742123.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_054728447.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054730957.1	4	Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1	"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism"
XP_054740345.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054732869.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-9665246;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810;Reactome: R-HSA-8863795;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-9665245;Reactome: R-HSA-1227986	"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII";"Downregulation of ERBB2 signaling";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2"
XP_054743683.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054730330.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054731738.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits"
XP_054741744.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054736682.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_054735500.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_054743107.1	2	Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14	"Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis"
XP_054738144.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054735836.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054740356.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054738476.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054730328.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054735270.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054730894.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054737521.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054739535.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_054729626.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054727342.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-418885;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-983231	"RHO GTPases activate IQGAPs";"DCC mediated attractive signaling";"EGFR downregulation";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"RHO GTPases Activate Formins";"Myogenesis";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"Factors involved in megakaryocyte development and platelet production"
XP_054731230.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054730427.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054733007.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054738038.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054731417.1	6	KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-5484;MetaCyc: PWY-8004;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycine, serine and threonine metabolism"
XP_054733230.1	5	Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054739587.1	8	KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_054731007.1	13	MetaCyc: PWY-561;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2	"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes"
XP_054738645.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054730999.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_054734750.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745002.1	8	Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-4615885	"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins"
XP_054746925.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_054741420.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-6174	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)"
XP_054736588.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054742214.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054744510.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054742091.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_054740968.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_054742069.1	5	Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-205043	"NF-kB is activated and signals survival";"Interleukin-1 signaling";"Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"NRIF signals cell death from the nucleus"
XP_054742488.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054738343.1	33	Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-72086;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-69273;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167158	"Transcription of the HIV genome";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"mRNA Capping";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the HIV-1 Early Elongation Complex"
XP_054742387.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054745150.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054742781.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054747716.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_054728965.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054731936.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_054738131.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054744878.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054740727.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054729836.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054733936.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054739819.1	3	MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis"
XP_054742335.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-167590	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation"
XP_054738262.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054747806.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054741807.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054740643.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_054743076.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054742324.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054734149.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054739709.1	3	Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969	"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina"
XP_054743807.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054734360.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054729449.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-8937144	"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Xenobiotics";"Endogenous sterols";"Aryl hydrocarbon receptor signalling"
XP_054738117.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054732555.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054741337.1	6	Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3322077	"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen synthesis"
XP_054730466.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_054731444.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054725947.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054734917.1	8	Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-74217;Reactome: R-HSA-6798695	"Surfactant metabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Neutrophil degranulation"
XP_054745377.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897	"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes"
XP_054745036.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_054738971.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054743221.1	9	Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167161	"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HIV Transcription Initiation"
XP_054727155.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054735966.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-426496	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs"
XP_054727541.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054742079.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2	"Ion channel transport";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis"
XP_054740978.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_054738484.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054747051.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054733400.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_054730020.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054733989.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054740628.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_054729260.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054732179.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054737278.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054730831.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054728625.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054729984.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054728975.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-4608870	"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins"
XP_054735517.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins"
XP_054729461.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054738894.1	17	Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557	"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis"
XP_054747067.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054725353.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054747858.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18	"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_054740912.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054734161.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054743066.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054738710.1	40	KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00903+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7778;MetaCyc: PWY-7007;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7656;MetaCyc: PWY-6945;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6863;MetaCyc: PWY-7606;MetaCyc: PWY-7094;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5177;MetaCyc: PWY-5109	"Geraniol degradation";"Pyruvate fermentation to butanol I";"Limonene and pinene degradation";"Caprolactam degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"2-methylpropene degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"Androstenedione degradation";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Propanoate metabolism";"Methyl tert-butyl ether degradation";"Benzoate degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Benzoyl-coa degradation I (aerobic)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Toluene degradation";"Phenylalanine metabolism";"Fatty acid elongation";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid salvage";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Glutaryl-coa degradation";"Fermentation to 2-methylbutanoate"
XP_054743922.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054733827.1	4	MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_054737595.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_054738961.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054731201.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-432040	"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054735189.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054745632.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_054745367.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_054726572.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054732939.1	25	Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8935964;Reactome: R-HSA-9018519;Reactome: R-HSA-8951911;Reactome: R-HSA-8940973;Reactome: R-HSA-8939256;Reactome: R-HSA-8877330;Reactome: R-HSA-8949275;Reactome: R-HSA-8941332;Reactome: R-HSA-8941284;Reactome: R-HSA-8939246;Reactome: R-HSA-8941858;Reactome: R-HSA-8939242;Reactome: R-HSA-8939247;Reactome: R-HSA-9616222;Reactome: R-HSA-8941326;Reactome: R-HSA-8931987;Reactome: R-HSA-8941333;Reactome: R-HSA-8939236;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8939245;Reactome: R-HSA-8939243	"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"RUNX1 regulates expression of components of tight junctions";"Estrogen-dependent gene expression";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates bone development";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054740630.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054729768.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054725997.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054740044.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054727981.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054728187.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054747389.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054733383.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_054729189.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054738052.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054743084.1	10	Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554	"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_054726170.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_054725154.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054743208.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054744660.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054740776.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054733685.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054734857.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054735499.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_054745538.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_054725655.1	7	KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism"
XP_054747470.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054738100.1	6	Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00030+5.1.3.1;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861	"Pentose phosphate pathway";"Rubisco shunt";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054741794.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054728497.1	52	Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-749476;Reactome: R-HSA-6803529;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73863;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-73772	"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Abortive And Retractive Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Promoter Escape"
XP_054742413.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054732134.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745326.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054742148.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054740838.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054747271.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054730117.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054743700.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054731127.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-5619107	"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_054730262.1	8	KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_054731243.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054726751.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054736375.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation"
XP_054741700.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054743512.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054738194.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch and sucrose metabolism"
XP_054728305.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_054732048.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054726993.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054740407.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054727534.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054729022.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054729966.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_054741295.1	8	Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-6798695	"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation"
XP_054732687.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-198323	"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol"
XP_054728459.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054730949.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth"
XP_054725782.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122	"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054727392.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948	"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants"
XP_054728835.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054747650.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054730621.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054731866.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054735457.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741483.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_054735921.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054729956.1	16	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint"
XP_054732847.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054742880.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054737068.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054730185.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_054727875.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054737857.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054729537.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054742014.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054726632.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_054739991.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054742404.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_054734851.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745202.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054735250.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054733762.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_054739969.1	15	Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_054736892.1	23	Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-6814122;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-418597	"G-protein activation";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events"
XP_054740085.1	20	KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-1268020;MetaCyc: PWY-6728;MetaCyc: PWY-7384;MetaCyc: PWY-5538	"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Reductive TCA cycle II";"Mitochondrial protein import";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI"
XP_054726761.1	11	MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-7560;MetaCyc: PWY-7102	"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"Methylerythritol phosphate pathway II";"Bisabolene biosynthesis (engineered)"
XP_054745572.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054742291.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054736396.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054735451.1	4	Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;MetaCyc: PWY-7927	"Degradation of cysteine and homocysteine";"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)"
XP_054726606.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome"
XP_054747422.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731617.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7185	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I"
XP_054727639.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054744158.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054740011.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054742490.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054746763.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054728290.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054738062.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601	"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_054731845.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054729511.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741300.1	9	Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086	"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen"
XP_054736533.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054735758.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054744026.1	16	MetaCyc: PWY-6886;MetaCyc: PWY-7124;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7218;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-8004	"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I"
XP_054733121.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_054725164.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054727082.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054743506.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054738676.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054744650.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737157.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054735511.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054741128.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054727829.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions"
XP_054730885.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054738083.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054740932.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054744051.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054733156.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-7587	"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)"
XP_054732147.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054728614.1	5	MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68	"Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054729758.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054732814.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054747057.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054725363.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054731028.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054732733.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054734278.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054745458.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054743970.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054745612.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-2046105;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-2046106;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism";"Class I peroxisomal membrane protein import"
XP_054730408.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054732080.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054740610.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054730018.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_054737232.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733207.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054743045.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341	"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors"
XP_054731644.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054737370.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_054731030.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054747789.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054745399.1	7	MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_054738421.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-69205	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription"
XP_054733644.1	5	KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853	"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)"
XP_054741045.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649	"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation"
XP_054730495.1	30	Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-2644607;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-917937;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546	"Vpu mediated degradation of CD4";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Iron uptake and transport";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Neddylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling"
XP_054737199.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054735956.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054730811.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_054731093.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_054725864.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054745678.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system"
XP_054725753.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_054747061.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_054740906.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054731821.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054730666.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054734212.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054747702.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_054737750.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054732197.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_054735995.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054743711.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054747510.1	14	Reactome: R-HSA-1483166;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;KEGG: 00564+2.3.1.42;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Synthesis of PA";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_054729706.1	26	Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-210744	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_054733108.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_054738137.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054747316.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054728403.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_054727597.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate"
XP_054741652.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054739925.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054741418.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-191859	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly"
XP_054745406.1	7	MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-7838;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism"
XP_054742097.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I"
XP_054741960.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054740883.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_054738743.1	5	KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism"
XP_054741008.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054738684.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054733600.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054743652.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054744302.1	7	Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_054729657.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual incision in TC-NER"
XP_054741284.1	5	KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782	"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis"
XP_054730456.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054742225.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054733694.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_054745583.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054740217.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054736653.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054741095.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054744806.1	7	Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_054728955.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054745432.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555	"Downstream signal transduction";"Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1"
XP_054742234.1	17	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-5358565	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_054743095.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_054734911.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054745371.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054732159.1	7	MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7210	"UTP and CTP dephosphorylation I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_054747226.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054731195.1	13	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"G alpha (12/13) signalling events";"Thermogenesis";"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"PI3K-Akt signaling pathway"
XP_054743785.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_054741737.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054731916.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054744593.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054726907.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054727559.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054739839.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054743331.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_054739292.1	7	KEGG: 00565+3.1.4.4;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039	"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Choline biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule"
XP_054747670.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054731338.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054740745.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_054725839.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054730951.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_054735732.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054738701.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054735222.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054736019.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054746947.1	5	MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_054736355.1	6	KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580	"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_054736980.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054731485.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054733210.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_054731437.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054734689.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054725934.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054740560.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054733485.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054731411.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_054732859.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054726412.1	4	KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_054740607.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054739581.1	14	MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191	"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC"
XP_054727742.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_054744299.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054733411.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054737849.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_054737402.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054734521.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054735312.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054745289.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054739139.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054740756.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054731320.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans"
XP_054725903.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054733718.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_054729995.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054726150.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054734416.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054732388.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054733320.1	3	MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700	"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)"
XP_054730516.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054728240.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_054743558.1	10	Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-432720	"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Lysosome Vesicle Biogenesis"
XP_054731895.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054731718.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs"
XP_054745287.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054740513.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054734879.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054744003.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054737529.1	83	Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-512988;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-9028335;Reactome: R-HSA-1963640;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-5654720;Reactome: R-HSA-5654712;Reactome: R-HSA-5655302;Reactome: R-HSA-8856825;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-8853334;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-167044;Reactome: R-HSA-9645135;Reactome: R-HSA-983695;Reactome: R-HSA-2029482;Reactome: R-HSA-9028731;Reactome: R-HSA-1250347;Reactome: R-HSA-109704;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-2424491;Reactome: R-HSA-5673001;Reactome: R-HSA-2871796;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-912631;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-5654719;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-5655291;Reactome: R-HSA-8875360;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-1433559;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-5654704;Reactome: R-HSA-5654699;Reactome: R-HSA-5663213;Reactome: R-HSA-180292;Reactome: R-HSA-5655253;Reactome: R-HSA-5654727;Reactome: R-HSA-9664565;Reactome: R-HSA-1839117;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-9026519;Reactome: R-HSA-6807004;Reactome: R-HSA-5654700;Reactome: R-HSA-179812	"FLT3 Signaling";"EGFR downregulation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"NCAM signaling for neurite out-growth";"RET signaling";"Activated NTRK2 signals through PI3K";"GRB2 events in ERBB2 signaling";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"PI-3K cascade:FGFR4";"FRS-mediated FGFR4 signaling";"Signaling by FGFR1 in disease";"Cargo recognition for clathrin-mediated endocytosis";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"Signalling to RAS";"STAT5 Activation";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of actin dynamics for phagocytic cup formation";"Activated NTRK2 signals through FRS2 and FRS3";"SHC1 events in ERBB4 signaling";"PI3K Cascade";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"DAP12 signaling";"RAF/MAP kinase cascade";"FCERI mediated MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"MET activates PTPN11";"PI-3K cascade:FGFR1";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling";"Regulation of signaling by CBL";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"PIP3 activates AKT signaling";"MET receptor recycling";"SHC-mediated cascade:FGFR4";"Signal regulatory protein family interactions";"MET activates RAS signaling";"Signaling by FGFR4 in disease";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal attenuation";"Downstream signal transduction";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Regulation of KIT signaling";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR2";"RHO GTPases Activate WASPs and WAVEs";"GAB1 signalosome";"Signaling by FGFR2 in disease";"Negative regulation of FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by cytosolic FGFR1 fusion mutants";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"Activated NTRK2 signals through RAS";"Negative regulation of MET activity";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling"
XP_054746131.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054726605.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_054727738.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054731263.1	4	KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642	"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation"
XP_054736395.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054740609.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054726973.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054734103.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276	"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"HCMV Early Events";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_054732489.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III"
XP_054736031.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state"
XP_054727372.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_054737847.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054726623.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054731846.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054725495.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054737114.1	9	KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061	"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I"
XP_054733439.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054746971.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_054727876.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_054746949.1	7	Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054739627.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054731342.1	11	KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5	"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_054727230.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054736407.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054727417.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054744640.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_054729380.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054739977.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_054742507.1	42	Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-5625886;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-977225;Reactome: R-HSA-5693571;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-3214841;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607	"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Amyloid fiber formation";"Nonhomologous End-Joining (NHEJ)";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"PKMTs methylate histone lysines";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends"
XP_054740796.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633	"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054728732.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13	"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione metabolism"
XP_054735441.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054735564.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741774.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054740086.1	20	KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-6969;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-6728;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403	"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Mitochondrial protein import";"Reductive TCA cycle II";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)"
XP_054727720.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054725837.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054732861.1	13	KEGG: 00640+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00630+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118	"Propanoate metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Ethanol oxidation";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Chitin degradation to ethanol"
XP_054726698.1	5	MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism"
XP_054728661.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_054744148.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation"
XP_054745448.1	12	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054739701.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054747688.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_054741739.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054727936.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-983168	"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054729479.1	2	Reactome: R-HSA-5576886;Reactome: R-HSA-1299308	"Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)"
XP_054742868.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054739837.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_054727557.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054743046.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation"
XP_054738292.1	34	Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-180746	"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Viral Messenger RNA Synthesis";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein"
XP_054730665.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054736978.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054740905.1	7	KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054726334.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054743229.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_054736628.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054735586.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054729748.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_054726592.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054741229.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054732157.1	7	MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_054725977.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054742099.1	6	Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-201722	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex"
XP_054733155.1	14	Reactome: R-HSA-1483166;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51	"Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism"
XP_054734939.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054727561.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054730886.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054725743.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054727176.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I"
XP_054734834.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054746476.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054729240.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054737313.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054726303.1	12	MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-6309;KEGG: 00270+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240	"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism"
XP_054746144.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054731282.1	8	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases"
XP_054732576.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054738139.1	5	KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Pyruvate metabolism"
XP_054747225.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054738753.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_054729204.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054740663.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054730174.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054728956.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054744805.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_054738864.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-110362	"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair"
XP_054745081.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054743642.1	13	Reactome: R-HSA-2022857;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206308;Reactome: R-HSA-1660662;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23	"Keratan sulfate degradation";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS IV - Morquio syndrome B";"Glycosphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_054742316.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_054729798.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054732931.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-174411	"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere"
XP_054740588.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_054733209.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101	"HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation"
XP_054733915.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054726542.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054742510.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054733541.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054744214.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_054725238.1	6	KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11	"Glycine, serine and threonine metabolism";"Methane metabolism";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis"
XP_054746052.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-1170546	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Prolactin receptor signaling"
XP_054743786.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054731196.1	8	Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway"
XP_054730675.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054736968.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054747315.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054727201.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_054747724.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054747059.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727383.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054729881.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054729705.1	26	Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519	"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression"
XP_054727571.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Integrin cell surface interactions";"Syndecan interactions";"ECM proteoglycans"
XP_054738363.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054727494.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688	"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL"
XP_054727549.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054735996.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054736211.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054726982.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054735614.1	7	MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;Reactome: R-HSA-73817	"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_054742226.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054730455.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054732566.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_054732360.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054729723.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054736643.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054730309.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation"
XP_054745015.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription"
XP_054747234.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_054736784.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054730839.1	3	MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158	"Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V"
XP_054739926.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054745405.1	7	MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80	"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism"
XP_054725676.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054734023.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_054738164.1	13	MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122	"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis"
XP_054742251.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054744105.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497;Reactome: R-HSA-3371568	"ESR-mediated signaling";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase"
XP_054739730.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054729614.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_054746800.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054725926.1	6	MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234	"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III"
XP_054731503.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054738496.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054739083.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054747279.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054733273.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_054737424.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-416993	"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"Trafficking of GluR2-containing AMPA receptors"
XP_054747613.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054735881.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_054741354.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054731896.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054734005.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054744247.1	10	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape"
XP_054730515.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054727685.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922	"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_054735233.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054734964.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162	"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_054729996.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054731619.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177	"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II"
XP_054732078.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054740755.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054730941.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_054728451.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054726140.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054742938.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054727611.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054740039.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054739967.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054742112.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis"
XP_054739421.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054743548.1	5	MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_054726391.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_054727866.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054746961.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Translation initiation complex formation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054725456.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054728671.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054733486.1	18	MetaCyc: PWY-5913;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Arginine biosynthesis"
XP_054726087.1	5	KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3	"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism"
XP_054739728.1	6	MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;MetaCyc: PWY-7286;Reactome: R-HSA-6785470	"Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion"
XP_054732849.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054727127.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054747440.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_054735491.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054736550.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054731486.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054746502.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054741764.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054727243.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054729539.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054736356.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_054727752.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054735469.1	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_054743853.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054739516.1	10	MetaCyc: PWY-6369;MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol"
XP_054742176.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054730287.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway"
XP_054725928.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054738498.1	4	Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054736544.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054738081.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054747454.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054732221.1	13	MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-7112;MetaCyc: PWY-6370	"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)"
XP_054725678.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054727061.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC"
XP_054736927.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054735609.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054732337.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054733324.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_054725361.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054733898.1	13	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"PI3K-Akt signaling pathway"
XP_054741986.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_054739572.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054726154.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054732950.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054732807.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054732385.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054743986.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054732662.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054737075.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054727057.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events"
XP_054728366.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping"
XP_054727868.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054725458.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_054728183.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054726475.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054732717.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054732311.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928	"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis"
XP_054743191.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736889.1	23	Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-392451	"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma"
XP_054730734.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054731805.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054735796.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054741340.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054736260.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_054731488.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054740441.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis"
XP_054731069.1	18	MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73614;MetaCyc: PWY-4202;MetaCyc: PWY-6620;Reactome: R-HSA-73621;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-6627;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;KEGG: 00983+2.4.2.3;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6644;KEGG: 00240+2.4.2.3	"Adenine and adenosine salvage III";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Pyrimidine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Pyrimidine metabolism"
XP_054728745.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054733214.1	11	Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-1268020;Reactome: R-HSA-5628897;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-111457	"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Mitochondrial protein import";"TP53 Regulates Metabolic Genes";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria"
XP_054740564.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054739518.1	10	Reactome: R-HSA-1855167;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-6372	"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_054733823.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054730224.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054731091.1	18	MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73614;MetaCyc: PWY-4202;MetaCyc: PWY-6620;Reactome: R-HSA-73621;MetaCyc: PWY-6608;MetaCyc: PWY-6611;MetaCyc: PWY-5532;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;KEGG: 00983+2.4.2.3;MetaCyc: PWY-6644;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.3	"Adenine and adenosine salvage III";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Arsenate detoxification I (mammalian)";"Guanine and guanosine salvage";"Pyrimidine catabolism";"Guanosine nucleotides degradation III";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Drug metabolism - other enzymes";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism"
XP_054736984.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054747063.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_054725357.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054735923.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054728958.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054737364.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_054740434.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054728493.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_054726959.1	24	Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-418217	"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta"
XP_054745164.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054743481.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054742876.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054739993.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744	"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_054735219.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054745382.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398	"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway"
XP_054725870.1	12	MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-1861	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054736966.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054727422.1	11	MetaCyc: PWY-6963;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle I";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis"
XP_054737182.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054729796.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_054730741.1	14	MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_054730347.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054740380.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_054732744.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054747514.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054736189.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054729609.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14	"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis"
XP_054735998.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_054741891.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749	"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs"
XP_054746799.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054733105.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054740403.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054745886.1	9	Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962	"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex"
XP_054741869.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054725572.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054746367.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-3371571;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948	"Trafficking of AMPA receptors";"Long-term potentiation";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"HSF1-dependent transactivation";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants"
XP_054731123.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_054741005.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)"
XP_054738680.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion"
XP_054729513.1	6	KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054742372.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054741964.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054733123.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_054744619.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054743280.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054727660.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_054727952.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation"
XP_054744855.1	5	KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4	"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism"
XP_054742866.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054743687.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_054735663.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054745174.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_054736102.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054730498.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054731640.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054728443.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_054741687.1	33	MetaCyc: PWY-5078;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6802;MetaCyc: PWY-6342;MetaCyc: PWY-5076;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00350+1.1.1.1;MetaCyc: PWY-1801;MetaCyc: PWY-5486;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7013;Reactome: R-HSA-71384;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5082;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5751;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-6871;MetaCyc: PWY-5079;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7111;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5480;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7396	"L-isoleucine degradation II";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis";"Noradrenaline and adrenaline degradation";"L-leucine degradation III";"Chloroalkane and chloroalkene degradation";"Protein S-nitrosylation and denitrosylation";"Tyrosine metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol II";"alpha-Linolenic acid metabolism";"(S)-propane-1,2-diol degradation";"Ethanol oxidation";"Glycine, serine and threonine metabolism";"Serotonin degradation";"L-methionine degradation III";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Phenylethanol biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Chitin degradation to ethanol";"3-methylbutanol biosynthesis (engineered)";"L-phenylalanine degradation III";"Naphthalene degradation";"Pyruvate fermentation to isobutanol (engineered)";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"Methane metabolism";"Pyruvate fermentation to ethanol I";"Retinol metabolism";"Butanol and isobutanol biosynthesis (engineered)"
XP_054734598.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-5610787	"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state"
XP_054732295.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054745446.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054738703.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054743635.1	5	KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-1222556;Reactome: R-HSA-392154	"Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase"
XP_054731034.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054736626.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054735588.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054731259.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054730791.1	11	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_054733148.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054742127.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054747742.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054739943.1	2	Reactome: R-HSA-1221632;Reactome: R-HSA-5601884	"Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis"
XP_054732512.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054738314.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_054726587.1	5	KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621	"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism"
XP_054747253.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706	"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054726947.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054741879.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054739777.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054726524.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_054743879.1	2	Reactome: R-HSA-532668;Reactome: R-HSA-6798695	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation"
XP_054747419.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054732084.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_054743624.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-7193;MetaCyc: PWY-6556	"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II"
XP_054728118.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_054745309.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_054742685.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_054731297.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054738813.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054730359.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054730405.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054741624.1	24	KEGG: 04150+2.7.11.11;Reactome: R-HSA-8853659;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-5610780;Reactome: R-HSA-163560;Reactome: R-HSA-422356;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-9634600;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-163358;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-4420097;Reactome: R-HSA-392517;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"mTOR signaling pathway";"RET signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism";"Regulation of insulin secretion";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"PKA-mediated phosphorylation of key metabolic factors";"HDL assembly";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"PKA activation";"VEGFA-VEGFR2 Pathway";"Rap1 signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_054741939.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054745292.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054727736.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054742494.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054740290.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_054738448.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_054733553.1	7	MetaCyc: PWY-7094;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;Reactome: R-HSA-77346;Reactome: R-HSA-1989781;KEGG: 00280+1.3.8.7;Reactome: R-HSA-77348	"Fatty acid salvage";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"PPARA activates gene expression";"Valine, leucine and isoleucine degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA"
XP_054743939.1	3	KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_054741834.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_054736778.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801	"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD"
XP_054728401.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_054745629.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_054728872.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054738779.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054728011.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_054739562.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-6804760;Reactome: R-HSA-3214858	"snRNP Assembly";"Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines"
XP_054742827.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054741304.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-7858;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-6920;MetaCyc: PWY-7007;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-5136;MetaCyc: PWY-7337;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;Reactome: R-HSA-9033241	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import"
XP_054737990.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054727226.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054725349.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054736651.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054741596.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054734046.1	6	MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6922	"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis"
XP_054740798.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628	"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_054743179.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054747664.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054735746.1	17	MetaCyc: PWY-5532;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-74259;Reactome: R-HSA-74217;MetaCyc: PWY-6608	"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine metabolism";"Adenine and adenosine salvage III";"Purine catabolism";"Purine salvage";"Guanosine nucleotides degradation III"
XP_054728037.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_054730188.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054737065.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054741141.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054745373.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054743803.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054727702.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054738113.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054745139.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_054737442.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054744146.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_054736500.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054741333.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054730680.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054740491.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054740647.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_054743333.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_054737339.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_054740469.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Degradation of AXIN";"Ub-specific processing proteases"
XP_054732452.1	8	Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription"
XP_054733530.1	18	Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00640+1.8.1.4;Reactome: R-HSA-70895;Reactome: R-HSA-71403;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00310+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;KEGG: 00280+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;KEGG: 00020+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-6783984	"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Propanoate metabolism";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Tryptophan metabolism";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycine degradation"
XP_054743911.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054740649.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_054743545.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_054744567.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054726817.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054737076.1	24	Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_054731077.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054741760.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054747444.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_054729172.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054737221.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054746890.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054734331.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1	"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism"
XP_054734785.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054728746.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054730572.1	18	Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;MetaCyc: PWY-8053	"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Anandamide biosynthesis II"
XP_054734472.1	9	Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-5667	"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_054730236.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054732492.1	12	Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2132295	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation"
XP_054737420.1	6	KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2	"Photosynthesis";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Oxidative phosphorylation"
XP_054745627.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054735401.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054738160.1	13	MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-6859	"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis"
XP_054742829.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_054725741.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054725347.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054742175.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054726020.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054725779.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054729610.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_054734317.1	4	KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030	"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis"
XP_054744600.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;Reactome: R-HSA-416476	"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events"
XP_054743985.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054732386.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054737311.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation"
XP_054726831.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054743556.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-182971	"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"EGFR downregulation"
XP_054731832.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054742547.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054734284.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054741350.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054726301.1	12	MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-801;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-6936;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187	"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine"
XP_054746480.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054736691.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054747557.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_054738668.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7180;MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336	"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054734843.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_054747293.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054739448.1	27	Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Viral Messenger RNA Synthesis";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_054745307.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_054732182.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054743521.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054745701.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054730930.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation"
XP_054733106.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_054725224.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_054730751.1	8	Reactome: R-HSA-70635;MetaCyc: PWY-4984;MetaCyc: PWY-7400;MetaCyc: PWY-4983;MetaCyc: PWY-5;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5154	"Urea cycle";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)"
XP_054746133.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054738901.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_054731261.1	12	Reactome: R-HSA-177929;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862	"Signaling by EGFR";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Collagen degradation";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054747876.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054746379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054731972.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054743416.1	12	MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-6683;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00230+2.7.1.25	"Sulfate activation for sulfonation";"Purine metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Assimilatory sulfate reduction III";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Purine metabolism"
XP_054734101.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_054743006.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054734266.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054747417.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054726621.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054739347.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054745408.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation"
XP_054741416.1	4	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054733972.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054736033.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040	"PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054729872.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054741006.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054742875.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054746973.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-5362768	"Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_054747228.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054742129.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054725314.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054744808.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054727942.1	4	Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375	"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I"
XP_054726589.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054745072.1	29	KEGG: 00830+1.1.1.1;MetaCyc: PWY-7396;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5079;MetaCyc: PWY-7111;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6333;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-5082;MetaCyc: PWY-6871;MetaCyc: PWY-7118;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6313;KEGG: 00260+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00625+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00071+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5078;MetaCyc: PWY-6342;MetaCyc: PWY-6587;MetaCyc: PWY-6802	"Retinol metabolism";"Butanol and isobutanol biosynthesis (engineered)";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to ethanol I";"L-phenylalanine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"Naphthalene degradation";"Acetaldehyde biosynthesis I";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"L-methionine degradation III";"3-methylbutanol biosynthesis (engineered)";"Chitin degradation to ethanol";"Metabolism of xenobiotics by cytochrome P450";"(S)-propane-1,2-diol degradation";"Serotonin degradation";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol II";"Chloroalkane and chloroalkene degradation";"L-leucine degradation III";"Fatty acid degradation";"L-tryptophan degradation V (side chain pathway)";"L-isoleucine degradation II";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol III";"Salidroside biosynthesis"
XP_054743689.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_054744772.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_054730928.1	5	Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"Formation of annular gap junctions";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_054735443.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054733132.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054736414.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_054729795.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054733460.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054731132.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_054732863.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054730678.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054738289.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_054731460.1	6	KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_054731918.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054727014.1	14	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase"
XP_054737744.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054742253.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054731271.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725680.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_054741126.1	52	Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-73780;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-76061;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-6796648	"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Chain Elongation";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054726502.1	22	Reactome: R-HSA-5675221;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025	"Negative regulation of MAPK pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation"
XP_054739081.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054747243.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054746035.1	4	Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-982772;Reactome: R-HSA-2586552	"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Growth hormone receptor signaling";"Signaling by Leptin"
XP_054736187.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054730406.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054744121.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_054743867.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054742686.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054744845.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054729862.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism"
XP_054733650.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_054729607.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_054731026.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054734830.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054735231.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054746797.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054730943.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054741602.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054731650.1	12	KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527	"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Stachyose degradation"
XP_054747866.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_054727613.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054745445.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054736124.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_054726484.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_054737578.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_054728219.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054734394.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054730777.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054730349.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054735162.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054738726.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962	"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex"
XP_054742009.1	13	MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662	"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism"
XP_054744631.1	28	Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-110320;Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-69166	"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"HSF1 activation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Meiotic recombination";"Activation of ATR in response to replication stress";"Translesion Synthesis by POLH";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate"
XP_054728673.1	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_054730668.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054740908.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_054737794.1	3	Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13	"G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054733470.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_054726330.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054735493.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054739015.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_054729745.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054736625.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054744030.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054741826.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054747827.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054735745.1	2	MetaCyc: PWY-6938;Reactome: R-HSA-430039	"NADH repair";"mRNA decay by 5' to 3' exoribonuclease"
XP_054744207.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054725359.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054745083.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054744783.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054741595.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054733858.1	11	MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-6969;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254	"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)"
XP_054725888.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054744093.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054744145.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_054735183.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054741770.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054735560.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054737452.1	7	MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-6855	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway";"Chitin degradation I (archaea)"
XP_054733051.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054742165.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054725397.1	4	KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_054727381.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054727573.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054726052.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054732442.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054727735.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_054736824.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054736398.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054730860.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054736213.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054726608.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054730289.1	3	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193;Reactome: R-HSA-936837	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Ion transport by P-type ATPases"
XP_054729327.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054726100.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054732904.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054739680.1	6	MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054741322.1	10	KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096	"Galactose metabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation"
XP_054732055.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054735766.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054747644.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054747030.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054742654.1	8	KEGG: 00240+3.5.4.5;MetaCyc: PWY-7181;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;MetaCyc: PWY-7193;Reactome: R-HSA-73614;MetaCyc: PWY-7199	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides degradation";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage"
XP_054727715.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054743370.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695	"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation"
XP_054728396.1	6	KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054744201.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054740332.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054745800.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595	"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs"
XP_054737130.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054729643.1	42	MetaCyc: PWY-7726;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-5789;MetaCyc: PWY-7007;MetaCyc: PWY-6883;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7401;MetaCyc: PWY-5138;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-5177;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6863;MetaCyc: PWY-5136;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-7656;MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00650+4.2.1.17+1.1.1.35	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Tryptophan metabolism";"Androstenedione degradation";"Lysine degradation";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"2-methylpropene degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Geraniol degradation";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Limonene and pinene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Aminobenzoate degradation";"Fatty acid salvage";"Glutaryl-coa degradation";"Fatty acid degradation";"Fermentation to 2-methylbutanoate";"Butanoate metabolism";"Fatty acid elongation";"Phenylalanine metabolism";"beta-Alanine metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"Propanoate metabolism";"Methyl tert-butyl ether degradation";"Benzoate degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism"
XP_054740594.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_054747145.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054729784.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_054744494.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054745330.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054738122.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054730850.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054740802.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633	"O-linked glycosylation";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054742569.1	4	Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5	"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism"
XP_054730552.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054725087.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_054744989.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_054727214.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054735356.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054745328.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054740270.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054743157.1	57	Reactome: R-HSA-180585;Reactome: R-HSA-8939902;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-174154;Reactome: R-HSA-4608870;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-174113	"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX2 expression and activity";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Asymmetric localization of PCP proteins";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1"
XP_054745894.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001	"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade"
XP_054727823.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054729727.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054736647.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054737056.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054747028.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054738367.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054737620.1	10	KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153	"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_054740651.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-399997	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion"
XP_054729237.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054738799.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054738632.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727805.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_054745999.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_054741232.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054727633.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054735237.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054741899.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690	"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"HCMV Early Events"
XP_054730002.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_054743616.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054739140.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054727198.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054744127.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054739797.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054736181.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_054743861.1	9	MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-7115	"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_054745052.1	7	KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation"
XP_054739087.1	8	KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1	"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway"
XP_054727690.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054747121.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054733277.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_054728729.1	10	MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-8001	"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis"
XP_054728054.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054734295.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054741994.1	14	Reactome: R-HSA-9648025;Reactome: R-HSA-9634638;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-3769402	"EML4 and NUDC in mitotic spindle formation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Deactivation of the beta-catenin transactivating complex"
XP_054738538.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054735152.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054744866.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054734208.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054743068.1	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)"
XP_054737532.1	83	Reactome: R-HSA-8853334;Reactome: R-HSA-5637810;Reactome: R-HSA-2219530;Reactome: R-HSA-5654733;Reactome: R-HSA-8851907;Reactome: R-HSA-9645135;Reactome: R-HSA-167044;Reactome: R-HSA-983695;Reactome: R-HSA-9028731;Reactome: R-HSA-2029482;Reactome: R-HSA-1250347;Reactome: R-HSA-1433557;Reactome: R-HSA-109704;Reactome: R-HSA-912526;Reactome: R-HSA-2179392;Reactome: R-HSA-9034864;Reactome: R-HSA-8983432;Reactome: R-HSA-9634285;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-2424491;Reactome: R-HSA-5673001;Reactome: R-HSA-2871796;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-5654693;Reactome: R-HSA-5654695;Reactome: R-HSA-9607240;Reactome: R-HSA-182971;Reactome: R-HSA-512988;Reactome: R-HSA-1250196;Reactome: R-HSA-8875555;Reactome: R-HSA-2428933;Reactome: R-HSA-375165;Reactome: R-HSA-8853659;Reactome: R-HSA-1963640;Reactome: R-HSA-9028335;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-5654720;Reactome: R-HSA-5655302;Reactome: R-HSA-5654712;Reactome: R-HSA-8856825;Reactome: R-HSA-74751;Reactome: R-HSA-180336;Reactome: R-HSA-74749;Reactome: R-HSA-186763;Reactome: R-HSA-1236382;Reactome: R-HSA-5654688;Reactome: R-HSA-1433559;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-5654704;Reactome: R-HSA-5654699;Reactome: R-HSA-180292;Reactome: R-HSA-5663213;Reactome: R-HSA-5655253;Reactome: R-HSA-5654727;Reactome: R-HSA-9664565;Reactome: R-HSA-1839117;Reactome: R-HSA-2871809;Reactome: R-HSA-5654726;Reactome: R-HSA-5654710;Reactome: R-HSA-354194;Reactome: R-HSA-9026519;Reactome: R-HSA-6807004;Reactome: R-HSA-179812;Reactome: R-HSA-5654700;Reactome: R-HSA-8865999;Reactome: R-HSA-5654689;Reactome: R-HSA-9027284;Reactome: R-HSA-210993;Reactome: R-HSA-1295596;Reactome: R-HSA-912631;Reactome: R-HSA-2730905;Reactome: R-HSA-389359;Reactome: R-HSA-1257604;Reactome: R-HSA-8875656;Reactome: R-HSA-5654719;Reactome: R-HSA-391160;Reactome: R-HSA-8851805;Reactome: R-HSA-5655291;Reactome: R-HSA-8875360	"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of FGFR4 signaling";"MET activates PI3K/AKT signaling";"STAT5 Activation";"Signalling to RAS";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Activated NTRK2 signals through FRS2 and FRS3";"Regulation of actin dynamics for phagocytic cup formation";"SHC1 events in ERBB4 signaling";"Signaling by SCF-KIT";"PI3K Cascade";"Interleukin receptor SHC signaling";"EGFR Transactivation by Gastrin";"Activated NTRK3 signals through RAS";"Interleukin-15 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"DAP12 signaling";"RAF/MAP kinase cascade";"FCERI mediated MAPK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"FRS-mediated FGFR1 signaling";"PI-3K cascade:FGFR2";"FLT3 Signaling";"EGFR downregulation";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB2 signaling";"MET activates RAP1 and RAC1";"SHC-related events triggered by IGF1R";"NCAM signaling for neurite out-growth";"RET signaling";"GRB2 events in ERBB2 signaling";"Activated NTRK2 signals through PI3K";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"PI-3K cascade:FGFR4";"Signaling by FGFR1 in disease";"FRS-mediated FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Insulin receptor signalling cascade";"SHC1 events in EGFR signaling";"Signal attenuation";"Downstream signal transduction";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SHC-mediated cascade:FGFR1";"Regulation of KIT signaling";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR2";"GAB1 signalosome";"RHO GTPases Activate WASPs and WAVEs";"Signaling by FGFR2 in disease";"Negative regulation of FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by cytosolic FGFR1 fusion mutants";"FCERI mediated Ca+2 mobilization";"Negative regulation of FGFR1 signaling";"PI-3K cascade:FGFR3";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Activated NTRK2 signals through RAS";"Negative regulation of MET activity";"GRB2 events in EGFR signaling";"FRS-mediated FGFR2 signaling";"MET activates PTPN11";"PI-3K cascade:FGFR1";"Erythropoietin activates RAS";"Tie2 Signaling";"Spry regulation of FGF signaling";"Regulation of signaling by CBL";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent Vav1 pathway";"PIP3 activates AKT signaling";"MET receptor recycling";"SHC-mediated cascade:FGFR4";"Signal regulatory protein family interactions";"MET activates RAS signaling";"Signaling by FGFR4 in disease";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_054733660.1	6	KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709	"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_054744362.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054744637.1	25	Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Cilium Assembly";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054727604.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054730478.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-8948751;Reactome: R-HSA-382556;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-5632684;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-983168	"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN stability and activity";"ABC-family proteins mediated transport";"Separation of Sister Chromatids";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog 'on' state";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054731660.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054741900.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900	"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4"
XP_054727105.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054730749.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036	"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II"
XP_054736996.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_054726220.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054725982.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598	"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis"
XP_054734810.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism"
XP_054739963.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054744184.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_054726627.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054747411.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814	"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes"
XP_054740022.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054746741.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_054732853.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054726977.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054741871.1	42	Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-3214842;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-110331;Reactome: R-HSA-201722;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-5625886;Reactome: R-HSA-427389;Reactome: R-HSA-977225;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-110329;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8939236;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-912446	"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"HDMs demethylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cleavage of the damaged purine";"Formation of the beta-catenin:TCF transactivating complex";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Amyloid fiber formation";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Cleavage of the damaged pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Late Events";"PKMTs methylate histone lysines";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination"
XP_054736586.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054745656.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import"
XP_054730351.1	3	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054744230.1	3	MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8	"L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation"
XP_054733112.1	3	Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054736434.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_054737558.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054729838.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054730122.1	7	Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-203927	"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis"
XP_054743944.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054731267.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054727640.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725480.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054744007.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism"
XP_054739698.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054727034.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054725909.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_054729522.1	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"RSK activation"
XP_054732988.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054725833.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054740531.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_054741078.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054744228.1	56	Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-174113;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-382556;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837	"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"ABC-family proteins mediated transport";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Neddylation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation"
XP_054742525.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727025.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-166208	"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTORC1-mediated signalling"
XP_054738552.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054733670.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054725281.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054744372.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_054743078.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054728142.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054736946.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054743436.1	3	MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753	"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_054739973.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447	"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria"
XP_054747210.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_054745645.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054733251.1	5	Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108	"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis"
XP_054730632.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_054726743.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054726252.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_054725714.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_054745038.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054735044.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_054733178.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054734744.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054730216.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway"
XP_054744902.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689	"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits"
XP_054741171.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054739714.1	3	KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664	"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K"
XP_054741258.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054737143.1	7	MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539	"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism"
XP_054735031.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054737227.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Starch and sucrose metabolism"
XP_054744599.1	9	MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events"
XP_054740461.1	14	KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-7254;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-6728	"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle"
XP_054727553.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054737331.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054731071.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054747916.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054726811.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054731812.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054741917.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054726666.1	37	Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3232142;Reactome: R-HSA-4615885;Reactome: R-HSA-9639288;Reactome: R-HSA-168325;Reactome: R-HSA-2132295;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-983170;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-204005	"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"SUMOylation of ubiquitinylation proteins";"SUMOylation of DNA replication proteins";"Amino acids regulate mTORC1";"Viral Messenger RNA Synthesis";"MHC class II antigen presentation";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"snRNP Assembly";"COPII-mediated vesicle transport"
XP_054743917.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054738478.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054730326.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054735838.1	4	KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I"
XP_054745844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054733316.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054740260.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054743931.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054745117.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054736479.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054732786.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054745262.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054739215.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_054739909.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054726837.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054727079.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054742541.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054737317.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054737652.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054734311.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054735017.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054729628.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054746734.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_054739592.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656	"TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling"
XP_054737284.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054744557.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054728980.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054738036.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054740457.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054728019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054729653.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054738190.1	6	MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900	"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_054742145.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054730840.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_054727593.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_054742093.1	4	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism"
XP_054740459.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN"
XP_054727806.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_054736699.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054736477.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054747654.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054728838.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054739850.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054727530.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054725478.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_054732193.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054742577.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054737319.1	16	Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX"
XP_054737055.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054727336.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Unwinding of DNA";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054726839.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054744597.1	4	Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis"
XP_054732970.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054727716.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054734904.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054737046.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054741080.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_054738605.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_054727832.1	12	MetaCyc: PWY-7221;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-5673001	"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Long-term potentiation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade"
XP_054744664.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054739552.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_054741575.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054727528.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054728820.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054732056.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_054743919.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054733047.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054725658.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054747146.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054738623.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_054728031.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054731180.1	6	MetaCyc: PWY-6606;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Purine catabolism";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III"
XP_054743790.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054736657.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054735540.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054732128.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_054737229.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054729142.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054728630.1	17	Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-975163;Reactome: R-HSA-937042;Reactome: R-HSA-168638;Reactome: R-HSA-202424;Reactome: R-HSA-937072;Reactome: R-HSA-5357956	"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex";"NOD1/2 Signaling Pathway";"Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TNFR1-induced NFkappaB signaling pathway"
XP_054747855.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_054731433.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_054745465.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway"
XP_054747342.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726581.1	9	MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5744	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation"
XP_054732300.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054733433.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054738890.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054737598.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054742121.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054729540.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054740634.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_054731490.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054730087.1	18	Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054738303.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054728138.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054736995.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_054743681.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054730024.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_054740975.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_054726292.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054728120.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_054742762.1	5	Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838	"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO"
XP_054738480.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054735286.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_054731269.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054738909.1	4	MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054741615.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054740519.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_054740625.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_054727132.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_054734873.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054726874.1	4	KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_054743615.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054743529.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054731014.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054739478.1	17	Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174178	"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054729842.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy"
XP_054726515.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054733942.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054742856.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054729980.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054733880.1	7	Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"
XP_054732394.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054737275.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054726979.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054734296.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054728978.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054734364.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane"
XP_054729396.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054747534.1	4	Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_054740780.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054730341.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054727026.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054734255.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054742526.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054727650.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054740033.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-6607;MetaCyc: PWY-5381;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II"
XP_054743487.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054729482.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054729533.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054725520.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054745646.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054727501.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054741487.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20	"Neutrophil degranulation";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism"
XP_054742411.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_054725538.1	7	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway"
XP_054747273.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054739089.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_054728152.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_054746928.1	7	MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-5686	"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis I"
XP_054736070.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054726242.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes"
XP_054734754.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054726753.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054734246.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054739632.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054726991.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054728285.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054742808.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054739799.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054745154.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054728237.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_054744129.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054738369.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054727543.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054739216.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_054738797.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-6798695	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Neutrophil degranulation"
XP_054729239.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054747053.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054733315.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054732737.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054738140.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560	"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism"
XP_054730833.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054745353.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054727067.1	3	KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44	"Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054742567.1	10	MetaCyc: PWY-7922;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-913709	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins"
XP_054743248.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054741159.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054728550.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054739538.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054742694.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054734882.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054725089.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_054731234.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054738648.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054736467.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events"
XP_054729054.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_054736649.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054732095.1	5	MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;MetaCyc: PWY-6012;KEGG: 00770+2.7.8.7;Reactome: R-HSA-199220	"Acyl carrier protein activation";"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Pantothenate and CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism"
XP_054736671.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054738087.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054735533.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_054725351.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054739520.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_054729463.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054725757.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054735482.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_054726496.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054744674.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054744547.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054728852.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054738024.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054740669.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054736758.1	13	MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52	"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054732652.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054731203.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054735590.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054741740.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054726665.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054726382.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054731787.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054730334.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054747915.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_054730804.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054731735.1	22	Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-9648025;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"EML4 and NUDC in mitotic spindle formation";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated"
XP_054733381.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"