Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_050306061.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050295465.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050307788.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050302232.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050309805.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050301980.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_050307555.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_050302908.1 4 KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_050309688.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050297604.1 5 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway" XP_050304397.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050316340.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_050310617.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050303580.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050299625.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897 "Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes" XP_050314894.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050309101.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050314849.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050307985.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050296066.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050302660.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050309481.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_050300752.1 5 Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_050312858.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050293094.1 32 Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-77075 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE" XP_050304580.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_050307075.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050299270.1 31 KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;Reactome: R-HSA-9029558 "Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Biotin metabolism";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_050292856.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050315657.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" XP_050311681.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_050299941.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050314497.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050304591.1 6 MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_050298271.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050303274.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050305790.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050314198.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050303184.1 11 Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-114604;Reactome: R-HSA-9008059 "Costimulation by the CD28 family";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"GPVI-mediated activation cascade";"Interleukin-37 signaling" XP_050299326.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" XP_050309592.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050310238.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050303755.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_050311567.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050296210.1 9 KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II" XP_050303128.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-7356 "Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine salvage IV (yeast)" XP_050313485.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050305918.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050302182.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050314307.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050304236.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_050308615.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050315142.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_050295569.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050306629.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" XP_050309463.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050311105.1 12 KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409 "alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_050300581.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production" XP_050314012.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050297945.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050305877.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_050299318.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050315129.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050309594.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148 "Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050302755.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050293995.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_050313928.1 17 Reactome: R-HSA-2426168;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2 "Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism" XP_050293322.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619 "TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN" XP_050297821.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_050314337.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050297009.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_050306793.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050292745.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"Macroautophagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins" XP_050303364.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_050302129.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_050309108.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050298975.1 12 KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7294;MetaCyc: PWY-7295;MetaCyc: PWY-6728;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-5749;MetaCyc: PWY-7854 "Pyruvate metabolism";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate assimilation";"D-xylose degradation IV";"L-arabinose degradation IV";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Itaconate degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_050308961.1 3 Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050296291.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification" XP_050316334.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050310743.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_050305870.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050299986.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050312419.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050299763.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050298521.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_050312829.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210 "Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Polymerase switching";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_050294287.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050295478.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167287 "Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery" XP_050295642.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_050309798.1 10 MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559 "Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway" XP_050295579.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050305911.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050311491.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050301443.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling" XP_050312133.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_050302412.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_050301978.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050303026.1 8 KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis" XP_050306949.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_050301686.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050310630.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress" XP_050293023.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050312330.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050301740.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_050304663.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_050308523.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325 "SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis" XP_050293015.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_050310449.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050309503.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_050310253.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050300873.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes" XP_050297694.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050295950.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050314898.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050301360.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050306575.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_050302361.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050313575.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050300758.1 6 MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I" XP_050296791.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_050307346.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050302014.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050307766.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050307324.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_050315852.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050301688.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050305992.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_050310706.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_050303616.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050299198.1 7 KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174 "Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_050309211.1 7 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_050296966.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050303613.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050296552.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050314203.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050294010.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" XP_050304632.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_050302636.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050311129.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050313117.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241 "Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import" XP_050298323.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050293041.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-9022692;Reactome: R-HSA-6804756;Reactome: R-HSA-9648025;Reactome: R-HSA-174178;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2467813;KEGG: 04926+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-68877;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2500257 "Thermogenesis";"RHO GTPases Activate Formins";"Regulation of MECP2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"EML4 and NUDC in mitotic spindle formation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Separation of Sister Chromatids";"Relaxin signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Human papillomavirus infection";"Mitotic Prometaphase";"Human cytomegalovirus infection";"Resolution of Sister Chromatid Cohesion" XP_050308601.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050312222.1 3 MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol" XP_050307455.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050308472.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_050309183.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050308624.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_050307390.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050305387.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050309297.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_050315135.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050305648.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050299997.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_050298361.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050316189.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_050295671.1 14 MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Synthesis of PC";"Synthesis of PE";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis" XP_050293900.1 6 MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism" XP_050294194.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_050303827.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050311565.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_050296816.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050314474.1 16 Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-512988 "Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Rho GTPase cycle";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"RET signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_050298916.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050303080.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050294941.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_050307768.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050294636.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050301581.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050307147.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050312914.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_050300831.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208 "mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling" XP_050293882.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050296956.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050303192.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050311126.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050297235.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I" XP_050295177.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050296707.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050298327.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050314272.1 6 Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle" XP_050309161.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050292825.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482839 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE" XP_050303565.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050316284.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050315327.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050298959.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050315337.1 42 Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632 "DNA methylation";"Meiotic recombination";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HCMV Late Events";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"Meiotic synapsis" XP_050311716.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_050309480.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_050311402.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050306042.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050311374.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050308144.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_050313134.1 7 MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724 "Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II" XP_050301917.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_050315571.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050307110.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050303046.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling" XP_050302097.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159236 "SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050309341.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050308202.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050292852.1 13 MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-202433 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Generation of second messenger molecules" XP_050313767.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050308225.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_050314911.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050296276.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050299722.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050306060.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050315922.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781 "Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression" XP_050310757.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050309186.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509 "Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes" XP_050299496.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_050304552.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_050314416.1 6 KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780 "Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism" XP_050292807.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050307569.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050304982.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_050306858.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050310614.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050308099.1 4 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation" XP_050310456.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050306200.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050307405.1 13 MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2 "TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)" XP_050298523.1 7 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_050296738.1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-156581 "rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation" XP_050309012.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050292991.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_050314641.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050300598.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050295206.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594 "PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events" XP_050299983.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050305257.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050293139.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_050297570.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050295578.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050295221.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050297513.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050313288.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050299595.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050294939.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050308856.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050298603.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050293086.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_050297175.1 6 KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_050307779.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases" XP_050296128.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300476.1 4 Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_050305895.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_050315474.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_050307743.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_050314044.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_050305305.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050302565.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_050295322.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050295879.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050306737.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050293321.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050312326.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050308613.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294835.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050304350.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050313539.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304135.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_050306458.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050314186.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_050297551.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313869.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050308653.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050300830.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy" XP_050303928.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050294671.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_050311807.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050298106.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_050307691.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_050308453.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050304946.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050314501.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050300094.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_050306950.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_050311778.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050296745.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Methylation" XP_050300665.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050299656.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050293183.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_050316358.1 7 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_050300730.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050301817.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_050307003.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_050305729.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_050304066.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_050304494.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050309618.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_050309184.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines" XP_050301697.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_050312194.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050292824.1 18 Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism" XP_050301963.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_050309667.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_050299432.1 24 Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657 "Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors" XP_050310604.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050294239.1 3 MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987 "Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis" XP_050300282.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_050294479.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_050301121.1 7 KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis" XP_050308987.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050297360.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050304449.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_050309200.1 4 Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211 "ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes" XP_050310887.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-6794361 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins" XP_050316229.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_050295175.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050294464.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050295854.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050311106.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism" XP_050309118.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_050297927.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation" XP_050298920.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050292881.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050316165.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_050304450.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695 "Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation" XP_050313617.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050293673.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_050303025.1 8 KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism" XP_050293965.1 8 MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" XP_050303658.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050309893.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_050305249.1 20 MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_050306064.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050298408.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050308117.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050313765.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050299226.1 10 Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1 "Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Thermogenesis" XP_050299883.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_050300583.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-180024 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events" XP_050309966.1 11 MetaCyc: PWY-6964;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2 "Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis" XP_050302960.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050299457.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_050304025.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_050304011.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050296388.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050305472.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050307840.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050300874.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050315606.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050313139.1 11 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_050316214.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050304553.1 11 MetaCyc: PWY-5695;MetaCyc: PWY-6538;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Theophylline degradation";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_050308116.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_050313079.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_050303747.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_050296955.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050308919.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_050311975.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050306273.1 5 Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234174;Reactome: R-HSA-1234176;Reactome: R-HSA-1234158 "PTK6 Expression";"Neddylation";"Cellular response to hypoxia";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of gene expression by Hypoxia-inducible Factor" XP_050298952.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050292774.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_050299628.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_050312429.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050298511.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050305322.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_050293310.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050297131.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation" XP_050314084.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_050296391.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050312367.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_050301096.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294186.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism" XP_050295197.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050301365.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_050296744.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050309487.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_050300712.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_050314381.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050300963.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_050314082.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER" XP_050313666.1 52 Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-167287 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery" XP_050315794.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_050312688.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050294492.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050293052.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050301477.1 6 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane" XP_050295122.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050311247.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050315853.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050312692.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050301546.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_050296989.1 8 Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-71336 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway" XP_050304248.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364 "RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_050302556.1 3 Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17 "Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism" XP_050304118.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050295870.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_050299285.1 10 Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397 "Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_050294037.1 10 MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Pentose phosphate pathway" XP_050304673.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050313135.1 7 KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941 "Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II" XP_050312450.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_050310257.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050297018.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050296277.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050304161.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050302150.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA" XP_050297097.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_050310074.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050298643.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050306832.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_050295910.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050296023.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050304459.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050308416.1 6 Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952 "Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation" XP_050312974.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050295640.1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" XP_050302701.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050304351.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050304804.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1" XP_050311215.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_050310980.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321 "Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_050294070.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813 "Truncations of AMER1 destabilize the destruction complex";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids" XP_050311151.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_050305735.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050312828.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_050313614.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050300285.1 3 Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389 "Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_050304320.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050304593.1 6 MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183 "D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_050300063.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation" XP_050295275.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_050299282.1 10 MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism" XP_050309770.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050313550.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050307190.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_050312391.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050295207.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597 "Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events" XP_050315592.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050301028.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050293496.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_050310536.1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-350054 "Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway" XP_050295828.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050311375.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050314334.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050313737.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_050312255.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_050311447.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789 "Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_050313294.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050309861.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050309187.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines" XP_050312744.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_050306662.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050309102.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050294471.1 4 KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III" XP_050312523.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050304811.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050301161.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_050312401.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050303037.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050302759.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_050312163.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_050309621.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_050308374.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_050305741.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311350.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses" XP_050300040.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_050307328.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation" XP_050305878.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_050294252.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)" XP_050301119.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_050296093.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311614.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050309689.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050304803.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_050308858.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_050303238.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050304808.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_050295623.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050301649.1 56 Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"UCH proteinases";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)" XP_050295336.1 3 Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism" XP_050305161.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050306748.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex" XP_050310615.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050311250.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_050297189.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050302407.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050300932.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050294400.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_050310263.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050309007.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050311444.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050308130.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333 "HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_050294509.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050315767.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050302662.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050294388.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_050314747.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_050308968.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_050307890.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_050304504.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_050294410.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050300698.1 17 MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_050310110.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_050301141.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050306659.1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_050314779.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050300404.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_050310259.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050311466.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050293490.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050304301.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050312218.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_050311376.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050314610.1 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_050309210.1 7 KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis" XP_050303449.1 16 MetaCyc: PWY-7124;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-6901 "Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation" XP_050298962.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_050306176.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050299283.1 10 MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-6527 "D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation" XP_050301128.1 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_050294505.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_050294391.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_050313129.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214 "Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins" XP_050311659.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_050304019.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050309954.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events" XP_050315478.1 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_050295071.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_050294064.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_050314344.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_050295054.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_050296693.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050316024.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_050311583.1 5 MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_050304938.1 16 Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-2132295 "Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"MHC class II antigen presentation" XP_050294068.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_050293035.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176 "Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis" XP_050310380.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050302395.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050303134.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_050294971.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050301372.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050295456.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050309474.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050311124.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050315974.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050296143.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_050310398.1 10 KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-5022 "Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"L-glutamate degradation IV";"Butanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V" XP_050300355.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050312010.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050311047.1 7 Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050306470.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050296412.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_050309188.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050311854.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050307243.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050312428.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050302842.1 17 Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174437 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand" XP_050293597.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050293065.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_050297750.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050314617.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050299227.1 10 Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1 "Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"PI3K-Akt signaling pathway" XP_050306728.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_050308065.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050313281.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_050306083.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTOR signalling" XP_050303234.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050303113.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050316290.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050299715.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050294834.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_050302251.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050297508.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050310626.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050312845.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050304116.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins" XP_050303918.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050294718.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050294674.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050293025.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050293305.1 15 MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;Reactome: R-HSA-70171 "Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis" XP_050304502.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050302392.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050297815.1 83 Reactome: R-HSA-8853659;Reactome: R-HSA-5654695;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-912631;Reactome: R-HSA-9634285;Reactome: R-HSA-983695;Reactome: R-HSA-8851907;Reactome: R-HSA-1963640;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-5654719;Reactome: R-HSA-1250347;Reactome: R-HSA-9034864;Reactome: R-HSA-5654704;Reactome: R-HSA-8875555;Reactome: R-HSA-74751;Reactome: R-HSA-375165;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5654726;Reactome: R-HSA-74749;Reactome: R-HSA-9607240;Reactome: R-HSA-512988;Reactome: R-HSA-9028335;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-9026519;Reactome: R-HSA-8851805;Reactome: R-HSA-186763;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-8865999;Reactome: R-HSA-5655302;Reactome: R-HSA-9645135;Reactome: R-HSA-6811558;Reactome: R-HSA-2428933;Reactome: R-HSA-1839117;Reactome: R-HSA-5654710;Reactome: R-HSA-8875656;Reactome: R-HSA-180292;Reactome: R-HSA-180336;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-8853334;Reactome: R-HSA-2424491;Reactome: R-HSA-9028731;Reactome: R-HSA-8983432;Reactome: R-HSA-1433557;Reactome: R-HSA-5654727;Reactome: R-HSA-1295596;Reactome: R-HSA-5654700;Reactome: R-HSA-2871796;Reactome: R-HSA-5654733;Reactome: R-HSA-389359;Reactome: R-HSA-8856825;Reactome: R-HSA-2730905;Reactome: R-HSA-5654720;Reactome: R-HSA-5654693;Reactome: R-HSA-5654699;Reactome: R-HSA-182971;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-109704;Reactome: R-HSA-1250196;Reactome: R-HSA-354194;Reactome: R-HSA-210993;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-5654689;Reactome: R-HSA-179812;Reactome: R-HSA-8853338;Reactome: R-HSA-167044;Reactome: R-HSA-2179392;Reactome: R-HSA-5654732;Reactome: R-HSA-2219530;Reactome: R-HSA-1433559;Reactome: R-HSA-6807004;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8875360;Reactome: R-HSA-5655253;Reactome: R-HSA-912526 "RET signaling";"PI-3K cascade:FGFR2";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Overexpressed ERBB2";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"MET activates PI3K/AKT signaling";"GRB2 events in ERBB2 signaling";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR4";"SHC1 events in ERBB4 signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR3";"MET activates RAP1 and RAC1";"Insulin receptor signalling cascade";"NCAM signaling for neurite out-growth";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Signal attenuation";"FLT3 Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK2 signals through PI3K";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"Activated NTRK2 signals through RAS";"MET activates RAS signaling";"Downstream signal transduction";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET activates PTPN11";"Signaling by FGFR1 in disease";"STAT5 Activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-related events triggered by IGF1R";"Signaling by cytosolic FGFR1 fusion mutants";"PI-3K cascade:FGFR3";"MET receptor recycling";"GAB1 signalosome";"SHC1 events in EGFR signaling";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR3 fusions in cancer";"DAP12 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin-15 signaling";"Signaling by SCF-KIT";"Negative regulation of FGFR2 signaling";"Spry regulation of FGF signaling";"FRS-mediated FGFR2 signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR4 signaling";"CD28 dependent Vav1 pathway";"Cargo recognition for clathrin-mediated endocytosis";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR4";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR2";"EGFR downregulation";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"PI3K Cascade";"SHC1 events in ERBB2 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Tie2 Signaling";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"PI-3K cascade:FGFR1";"GRB2 events in EGFR signaling";"Signaling by FGFR3 point mutants in cancer";"Signalling to RAS";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of KIT signaling";"Negative regulation of MET activity";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR2 in disease";"Interleukin receptor SHC signaling" XP_050310748.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_050306168.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050304295.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_050312394.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050295882.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_050311805.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050305897.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050315768.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050293591.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050305996.1 4 KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_050296090.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303115.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050314106.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050297217.1 4 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I" XP_050295868.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050312204.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050304010.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833 "Aggrephagy";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly" XP_050313119.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017 "Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_050311023.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)" XP_050302387.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050304952.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050308748.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_050299647.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050302543.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_050314890.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050309322.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050296121.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313443.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050296104.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050301950.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_050310077.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050296766.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050301637.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050310011.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_050301452.1 16 Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700 "Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_050297229.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_050303258.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_050308471.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_050302215.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_050302193.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050310331.1 6 Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731 "RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3" XP_050310943.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050305374.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_050299869.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_050308915.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex" XP_050303592.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_050304021.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050315687.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3 "Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism" XP_050308920.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_050297132.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050298118.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361 "Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_050307277.1 5 MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41 "Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system" XP_050293074.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050309119.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_050308662.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050300684.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050305350.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_050302681.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289 "Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation" XP_050297452.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050313085.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050302961.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050302031.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050295555.1 21 MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-6545 "Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_050296566.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050308751.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_050314803.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050302635.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050308157.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050296752.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050307275.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050300779.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_050308676.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling" XP_050309613.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050294372.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050295788.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050313537.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300451.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_050313034.1 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism" XP_050307950.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050301702.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050297061.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050315547.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_050305881.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311796.1 4 Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_050308114.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_050292768.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_050296091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050295904.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050298933.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050305456.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050295482.1 7 KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid" XP_050295746.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055 "Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_050296516.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_050312712.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_050308553.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism" XP_050308497.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050310805.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_050292700.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_050297494.1 5 MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26 "Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism" XP_050301692.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050313610.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050297241.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_050297221.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_050310229.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_050293420.1 6 KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-6309 "Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_050304776.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_050299568.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_050304696.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050314867.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_050303279.1 19 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5625970 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"Myogenesis";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1" XP_050296470.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050310944.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050296226.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_050293155.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_050298300.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_050301612.1 13 KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7184 "Pyrimidine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_050314250.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_050296137.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303813.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050300595.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_050307446.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050306808.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_050304402.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_050297499.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050299750.1 3 KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639 "Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis" XP_050297684.1 13 MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18 "Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes" XP_050295119.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050309552.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050293330.1 10 Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-983168 "NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050293733.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane" XP_050308630.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050305978.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050299029.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_050309603.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050314874.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_050295374.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_050304348.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050304809.1 5 Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_050305094.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_050307959.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_050316126.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_050298371.1 14 Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408 "Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation" XP_050296723.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_050300057.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050298401.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_050303574.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050298549.1 5 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_050303198.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_050297112.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050299754.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050296305.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050308423.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_050305763.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_050300711.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_050294843.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_050293227.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_050310882.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050293501.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050310574.1 7 KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7805 "Purine metabolism";"Glyphosate degradation III";"Adenine salvage";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation" XP_050297276.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415 "Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling" XP_050293317.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050311771.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_050293133.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_050293589.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050297707.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_050306462.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_050315674.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050296560.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-432722 "Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis" XP_050305272.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050307371.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050305397.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050315361.1 1 MetaCyc: PWY-6938 "NADH repair" XP_050298654.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246 "Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I" XP_050306814.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210 "Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_050301715.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050300797.1 12 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway" XP_050301400.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050311886.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050312193.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050302399.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050311993.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050312412.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050298229.1 4 KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_050293512.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050296272.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050304009.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9646399 "Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Aggrephagy" XP_050307550.1 8 MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_050309233.1 14 MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667 "Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I" XP_050309657.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050314875.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_050308688.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050309587.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050297497.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_050309549.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050313844.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_050309386.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_050299366.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050297179.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_050310929.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_050312456.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_050307654.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050312285.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050298405.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_050305774.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050305155.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_050309696.1 12 Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290 "Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_050309337.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050312400.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050301145.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050307787.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050316083.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_050295438.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050293637.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050305846.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_050301139.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050307294.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050296911.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050293389.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453 "ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response" XP_050297526.1 24 Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418597 "Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Ca2+ pathway";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events" XP_050303392.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050299328.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050296484.1 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" XP_050298247.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050307769.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050312153.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050295166.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050293699.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050303966.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050314878.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050316291.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050314434.1 12 Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-75893 "Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling" XP_050314343.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_050315744.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_050303521.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050315179.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050314439.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism" XP_050306708.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050295624.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050302609.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050297545.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304290.1 5 KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" XP_050301371.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050293228.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_050302365.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050308452.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_050303017.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050298831.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050308850.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050316332.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050300671.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050301475.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24 "Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_050308446.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050314576.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050303444.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_050316329.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050310069.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_050299719.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050315892.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050311153.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_050306617.1 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_050314081.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050310402.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050297568.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311548.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_050309005.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050311043.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050314673.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_050299230.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_050297362.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050314293.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_050296959.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050309225.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050310881.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725 "Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation" XP_050311495.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_050296125.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050297110.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_050311558.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050296149.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050309535.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801 "A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD" XP_050293315.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050304105.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050297042.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166 "Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA" XP_050309959.1 1 Reactome: R-HSA-419771 "Opsins" XP_050294785.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050308974.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_050309741.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050304005.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_050293163.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_050295849.1 12 MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4 "Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism" XP_050316235.1 7 KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11 "Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_050310540.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050294719.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_050304778.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_050311496.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_050294884.1 4 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis" XP_050311901.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050304715.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050314020.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050304381.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_050302751.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050309782.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_050309165.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050296852.1 8 Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation" XP_050312025.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050305955.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050316042.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_050310804.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_050310572.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" XP_050293117.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381042 "IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"PERK regulates gene expression" XP_050304415.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_050295852.1 17 Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-202424 "IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"Downstream TCR signaling" XP_050304432.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_050299712.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050315886.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050314414.1 13 MetaCyc: PWY-7384;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI" XP_050307383.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_050315060.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050299980.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050313574.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation" XP_050300115.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050315510.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050300233.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_050302250.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050314006.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050309625.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050298607.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050300955.1 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism" XP_050300814.1 5 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy" XP_050309236.1 14 Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055 "Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis" XP_050300897.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050297577.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304839.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050301166.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_050302125.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_050297704.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_050298128.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050310721.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050313508.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050307048.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1169408 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism" XP_050294013.1 10 KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11 "Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism" XP_050315750.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050308719.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050304028.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_050305096.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_050298372.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700 "Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_050295310.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_050296555.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050309346.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050299644.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050313780.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_050310095.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050309484.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_050312306.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050313578.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050305920.1 26 Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_050316359.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_050295020.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050299737.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_050299123.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_050311377.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050299846.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_050304556.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050304029.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_050301962.1 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" XP_050311097.1 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4 "Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism" XP_050296537.1 7 MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-8964208 "L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism" XP_050310423.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_050306535.1 4 Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753 "VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions" XP_050299329.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_050312506.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_050305097.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_050314031.1 10 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis" XP_050314495.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050306077.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_050299124.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050303066.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_050308527.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050308154.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050302208.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050311167.1 14 KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302 "Citrate cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)" XP_050297851.1 8 MetaCyc: PWY-6372;MetaCyc: PWY-6664;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;Reactome: R-HSA-1855183 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol" XP_050311777.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050310170.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050305982.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050312191.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050303663.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050301427.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050312411.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050297446.1 7 Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151 "Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_050313741.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050315968.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_050294434.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050306786.1 21 MetaCyc: PWY-7220;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7197;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050311911.1 6 MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia" XP_050305865.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050301219.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_050310333.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050292732.1 4 KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_050309784.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050300888.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050314822.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_050310886.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050311557.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_050299932.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050294318.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050310346.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050296811.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_050313069.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050300899.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_050300447.1 9 KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway" XP_050309738.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050299030.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_050314872.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050306552.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_050298280.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050302184.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050304800.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_050310556.1 11 KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III" XP_050308148.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050316040.1 10 MetaCyc: PWY-5839;MetaCyc: PWY-5844;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892 "Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis" XP_050303034.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050298140.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112 "Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification" XP_050307193.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_050293232.1 11 MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053 "2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II" XP_050308258.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050293421.1 6 MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" XP_050293789.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305732.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050304291.1 5 KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" XP_050301353.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_050315046.1 10 MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5844 "Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis" XP_050295577.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050303467.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050311907.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_050300548.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_050299162.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050293073.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_050312006.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313998.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway" XP_050301049.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism" XP_050305143.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050312854.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_050311408.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050307571.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050313738.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_050307693.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553 "O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs" XP_050296862.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050294865.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050297992.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050309383.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050295856.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050313282.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_050298711.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_050314827.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_050292773.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050313430.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050296610.1 10 MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922 "Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I" XP_050316177.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050303278.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_050297017.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050309600.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050306406.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050305102.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_050300936.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" XP_050307046.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-1169408 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"ISG15 antiviral mechanism" XP_050302604.1 8 KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism" XP_050313534.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050297698.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050306909.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050311172.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050314444.1 6 MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism" XP_050304239.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050299163.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050313679.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050316327.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050306714.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050296148.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050314814.1 13 Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8964038 "WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"LDL clearance" XP_050306739.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050313242.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050292809.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050297187.1 22 MetaCyc: PWY-7053;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7724 "Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_050294996.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050295030.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_050316265.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050303653.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050311994.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050298913.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050294655.1 11 Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-8862803;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472 "MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_050293510.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050300397.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050311381.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050303350.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313112.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_050314897.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050298598.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050301220.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_050314711.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050311559.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050303171.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050314392.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050307056.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050293419.1 6 KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-6309 "Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_050307410.1 7 KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-31 "Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Canavanine degradation" XP_050301591.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050313293.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050299736.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_050303606.1 27 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73856;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-77595;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6807505;Reactome: R-HSA-159231;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6803529 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA Derived from an Intronless Transcript";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing" XP_050309620.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis" XP_050312134.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050302423.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050302397.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050296413.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" XP_050303982.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050306488.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_050314877.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050300151.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050297038.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_050316366.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_050293884.1 7 KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23 "Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism" XP_050306237.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_050298601.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050312018.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050303195.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976 "Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols" XP_050308198.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050297768.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_050296891.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic" XP_050307656.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_050300878.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050296173.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050297596.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050314994.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_050297107.1 5 Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_050304637.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050310076.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050296094.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050309532.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050312103.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_050300667.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050296913.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_050312206.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050297766.1 13 MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590 "Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation" XP_050312696.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050303257.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_050310549.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050293000.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5467337 "S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding" XP_050310646.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050305650.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050314187.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_050308159.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_050307026.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_050306807.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_050313788.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050296198.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy" XP_050308100.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957 "rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050312080.1 9 Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-6703 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis" XP_050310355.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II" XP_050304112.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_050303729.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" XP_050301223.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050311996.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050301515.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826 "Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis" XP_050307450.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050296136.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305159.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_050296429.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_050311398.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050301024.1 4 KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" XP_050296559.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828 "Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis" XP_050294373.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050312366.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050304594.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_050298808.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050295280.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_050304954.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695 "Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation" XP_050296089.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050302705.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_050299933.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050299599.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050305363.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050316339.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_050311369.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050315746.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_050304868.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_050314485.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050294148.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050293245.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050315011.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050297873.1 9 MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94 "CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism" XP_050294476.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_050302805.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_050303262.1 8 KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis" XP_050299088.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050301016.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333 "HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_050313110.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_050306992.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050305778.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050310079.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050301433.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence" XP_050313507.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol" XP_050314077.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690 "Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events" XP_050310228.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050299718.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050295274.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050306857.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050306861.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_050312705.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_050312131.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050308046.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892 "Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)" XP_050299996.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_050296567.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050299643.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-75105 "Nuclear Receptor transcription pathway";"Fatty acyl-CoA biosynthesis" XP_050304955.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050302655.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638 "tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins" XP_050306865.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050295546.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-182218 "Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation" XP_050304796.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050304968.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050298409.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050297099.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-111932 "HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB" XP_050315626.1 20 MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538;Reactome: R-HSA-6798695 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation" XP_050316028.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51 "CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism" XP_050293047.1 16 Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-8004 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I" XP_050307657.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_050314796.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_050300271.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050293981.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050304961.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050296165.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_050308382.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050300354.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression" XP_050314268.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_050292849.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050304967.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_050299098.1 15 Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084 "CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_050315582.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" XP_050316167.1 57 Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178 "CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_050311872.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_050309219.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_050293803.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050308602.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300351.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050294759.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050303652.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050314366.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050296607.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_050311555.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050301523.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_050315549.1 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism" XP_050313198.1 7 Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_050309465.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050304299.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050304774.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_050310387.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_050308288.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_050311155.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_050293452.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050298133.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050301110.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_050311604.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_050296659.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_050300047.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_050313480.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-432142 "Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron assembly";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"VLDL clearance";"LDL remodeling";"LDL clearance";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Platelet sensitization by LDL" XP_050302881.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_050301406.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408 "Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation" XP_050312520.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050298947.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050308379.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050296964.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050312038.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050306661.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050304172.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050293037.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_050310395.1 6 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_050314904.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050303151.1 26 Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813 "Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids" XP_050312332.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050315470.1 3 Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_050296124.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050292770.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050294937.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050301952.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050301142.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050307066.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_050302754.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes" XP_050301163.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_050293010.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324 "Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_050308976.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_050296751.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050311370.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050298219.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050307362.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050309477.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_050308285.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_050303568.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050297874.1 9 MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902 "Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis" XP_050304067.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_050295743.1 10 MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_050301684.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_050307111.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050316410.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050301401.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050312856.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_050315760.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_050293779.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050302658.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050302183.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050314685.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050297232.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_050301918.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050307958.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_050314011.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050297866.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684 "Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state" XP_050304819.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050314795.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594 "PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events" XP_050305321.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050293314.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050295281.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_050310723.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050308294.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_050311680.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050307078.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050306349.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_050297628.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050303083.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050303100.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_050309452.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050301355.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_050312403.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050314794.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_050311981.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303871.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050305769.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050301676.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050306466.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes" XP_050308627.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228 "Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix" XP_050298860.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050298949.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168 "Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050311960.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050295172.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_050308195.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050295455.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4 "Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine metabolism" XP_050308874.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_050313532.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311710.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050313646.1 5 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)" XP_050308047.1 29 Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862 "Activation of the pre-replicative complex";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Translesion synthesis by POLK" XP_050299396.1 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_050300905.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050293631.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050299778.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_050302335.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050297453.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050293137.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_050298020.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050315463.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050314475.1 16 Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-114604 "Costimulation by the CD28 family";"Rho GTPase cycle";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"RET signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade" XP_050311128.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050308376.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050302440.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050304073.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_050315830.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050308193.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050302526.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_050315909.1 11 Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111458 "Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome" XP_050313559.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_050316385.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4641258 "G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Degradation of DVL" XP_050308383.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050309335.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050302816.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050308442.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_050316130.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_050313150.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050309120.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_050310251.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050293576.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050298048.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_050303095.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050307052.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72662 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" XP_050307962.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050292719.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050307529.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_050313933.1 17 KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599 "Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency" XP_050302921.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_050310006.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_050315120.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050298176.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050313693.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050310603.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050314644.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050299581.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050294991.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050304134.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_050299608.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_050296863.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050309766.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_050312177.1 6 Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)" XP_050296080.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_050313142.1 11 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050306522.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" XP_050312817.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_050312427.1 9 Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis" XP_050311792.1 6 Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism" XP_050310566.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_050308477.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050300922.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050315923.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472 "Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_050295251.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_050297004.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158 "Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V" XP_050304633.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_050299519.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050314057.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_050309586.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050312182.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050316396.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050304395.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050313931.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_050299398.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_050312483.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050307653.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_050305788.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050301105.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_050309214.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_050295349.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050310048.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_050316307.1 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_050311974.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050315821.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_050296132.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050302325.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050315672.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050303537.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050314876.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_050296713.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_050303544.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050302794.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050303823.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050301521.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_050309644.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_050300903.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050301902.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_050293147.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050313847.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_050299225.1 10 KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway" XP_050313792.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050300813.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation" XP_050306489.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_050294237.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050292776.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050308098.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050303387.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_050312359.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050307023.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050299268.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_050312414.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050293240.1 33 Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-168333 "RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_050296326.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_050315493.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050304407.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_050305935.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050312109.1 1 Reactome: R-HSA-419771 "Opsins" XP_050302403.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050313205.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_050305905.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050296126.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300297.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_050309780.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050315000.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050294135.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_050313240.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_050308097.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050308003.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_050316120.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_050296924.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050296870.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050294149.1 52 Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424 "Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling" XP_050313318.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050298902.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050297991.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050293205.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050315103.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050307900.1 19 Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Translation initiation complex formation";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_050293278.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_050310233.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050309370.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050304042.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_050298434.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050303738.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation" XP_050313416.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050300988.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_050295742.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411 "Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)" XP_050314801.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050309375.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205 "G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription" XP_050311890.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050296623.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050304451.1 57 Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949 "G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin" XP_050309185.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines" XP_050312493.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050314376.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253 "HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_050303824.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050316328.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050300930.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050292783.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050295297.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050311134.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050293973.1 6 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism" XP_050303750.1 6 KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221 "Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_050297015.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050313778.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs" XP_050313151.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_050303905.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_050294872.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050304757.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050303359.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050302424.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050315473.1 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_050302542.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_050310984.1 42 MetaCyc: PWY-5138;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7401;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35 "Fatty acid beta-oxidation IV (unsaturated, even number)";"Limonene and pinene degradation";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Androstenedione degradation";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"Toluene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Benzoate degradation";"Tryptophan metabolism";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Fatty acid degradation";"Aminobenzoate degradation";"Fatty acid salvage";"Butanoate metabolism";"Glutaryl-coa degradation";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation" XP_050311525.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_050311992.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313440.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050307936.1 29 Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-5693571;Reactome: R-HSA-69541;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Human papillomavirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"Nonhomologous End-Joining (NHEJ)";"Stabilization of p53";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway" XP_050316335.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050304739.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_050293984.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050310247.1 3 MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_050303861.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050308766.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_050299066.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_050311074.1 5 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_050306375.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_050314461.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050296290.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER" XP_050308140.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_050314476.1 16 Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-389357 "RET signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Rho GTPase cycle";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling" XP_050313202.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_050309464.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050293253.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage" XP_050295963.1 13 MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-5122 "Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis" XP_050315587.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050298403.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050307712.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050294875.1 9 MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism" XP_050303351.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050296100.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050298725.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_050307999.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_050300990.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050314024.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050311157.1 25 Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-381771;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657 "Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors" XP_050294487.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_050306046.1 5 Reactome: R-HSA-168315;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "Inhibition of Host mRNA Processing and RNA Silencing";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_050302614.1 12 Reactome: R-HSA-196780;KEGG: 00280+6.4.1.3;MetaCyc: PWY-5789;Reactome: R-HSA-71032;Reactome: R-HSA-3371599;MetaCyc: PWYG-321;KEGG: 00630+6.4.1.3;MetaCyc: PWY-6728;KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5743 "Biotin transport and metabolism";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propionyl-CoA catabolism";"Defective HLCS causes multiple carboxylase deficiency";"";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"3-hydroxypropanoate cycle" XP_050312445.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_050312254.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_050308532.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885 "snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins" XP_050300593.1 18 MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7176 "Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis" XP_050293717.1 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" XP_050308720.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108 "RORA activates gene expression";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_050297451.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050313968.1 11 KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Thermogenesis" XP_050300810.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway" XP_050299909.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_050293276.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_050302006.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_050315069.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050297981.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_050313356.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_050300180.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_050311798.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_050304547.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_050298333.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050306713.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050312344.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050312392.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050310738.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050309701.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050301276.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050309551.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924 "MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport" XP_050311112.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050309826.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_050298874.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases" XP_050307898.1 18 MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-5392 "Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II" XP_050301790.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050310562.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050303588.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_050296967.1 6 MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation" XP_050309107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294494.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050313845.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_050294882.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_050299731.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050293264.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050309396.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050296803.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050307795.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_050294863.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050314108.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050294853.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs" XP_050306991.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050295457.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_050313148.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050313623.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050314314.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050299926.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050307553.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_050310240.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050314893.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050307800.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_050300361.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050311453.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_050296452.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050310335.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050311774.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050301238.1 8 KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-5740 "Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis" XP_050309176.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050302239.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594 "Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events" XP_050314907.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_050304805.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041 "Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1" XP_050294240.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_050294824.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050303355.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis" XP_050294383.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_050294822.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050301683.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_050313841.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_050297691.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050308218.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050303376.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050297008.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis" XP_050311048.1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_050293611.1 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" XP_050295826.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050299567.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050303985.1 4 Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-5674400 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer" XP_050309006.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050303030.1 8 KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_050309700.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050298326.1 10 MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-6366;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6365 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis" XP_050309513.1 7 Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2 "Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism" XP_050315847.1 3 Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_050308137.1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481 "Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints" XP_050298143.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-6842 "Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II" XP_050297363.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_050301954.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_050310609.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050295735.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050312200.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050298509.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050299588.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_050295617.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050311523.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_050296551.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_050297626.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050311135.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050302233.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050297629.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050305166.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050308160.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050293138.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_050313627.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_050299852.1 13 MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050309949.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050305396.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050308735.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050302674.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_050298802.1 10 KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-6613 "One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_050295282.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_050308644.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050304141.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050315185.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050297695.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050314423.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181 "Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism" XP_050311490.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050300415.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_050297011.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II" XP_050304807.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_050312832.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051 "Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I" XP_050313801.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050314294.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_050304166.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050298868.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050301799.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050305641.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050304000.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_050310265.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050306897.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_050309121.1 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" XP_050293066.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-983189 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Kinesins" XP_050313263.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050293583.1 4 KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate" XP_050309485.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_050307086.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_050293629.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_050315826.1 4 MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_050294454.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050308926.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_050295641.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050310679.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" XP_050310978.1 5 Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580 "Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence" XP_050300038.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050292848.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050295619.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050312860.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_050314648.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050308702.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050293461.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_050307098.1 14 KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561 "Oxidative phosphorylation";"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_050300616.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050297637.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050307826.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_050294228.1 8 Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901 "Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation" XP_050306978.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050310784.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_050298276.1 7 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;Reactome: R-HSA-71336 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_050299178.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_050308879.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_050314873.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_050311824.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050309190.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050311498.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_050307621.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050304050.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050314712.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050293307.1 15 Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_050311391.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050308781.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050306166.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_050300762.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_050306505.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050315181.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050298535.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050313932.1 17 MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381 "3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_050305976.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050309651.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050316318.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Formation of apoptosome" XP_050298172.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_050309720.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050311956.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050312179.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange" XP_050297791.1 57 Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178 "CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_050300567.1 4 MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis" XP_050300401.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth" XP_050310045.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_050305749.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050300709.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_050305762.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_050301225.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050307740.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_050294499.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_050313379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050294440.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_050294714.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050292996.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_050313470.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050305256.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050299164.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050296771.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_050298329.1 5 MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_050303273.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050297708.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_050297576.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050308112.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_050301809.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174178 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_050304890.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050314042.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_050298863.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050303263.1 19 Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-114604 "RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate PAKs";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade" XP_050304977.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050300453.1 9 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_050306740.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050313940.1 7 MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205 "Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism";"Drug metabolism - other enzymes" XP_050312398.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050297619.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_050308612.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_050297177.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_050313133.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_050314936.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction" XP_050299372.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050305384.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050310065.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_050295131.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_050307884.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050296448.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_050314647.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050300149.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050313355.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_050314586.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_050316409.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_050302086.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_050301990.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311617.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050313289.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050299862.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_050297181.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_050312361.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_050296248.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050313237.1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_050301457.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050304829.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662 "Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism" XP_050295444.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050311409.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050304059.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_050310945.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_050300491.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900 "Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4" XP_050304818.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050311987.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050302128.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050314921.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050313674.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050293870.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050301602.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_050296822.1 6 Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-162594 "Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle" XP_050314054.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050306738.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050314017.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_050307920.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones" XP_050298867.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050308674.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050302671.1 6 Reactome: R-HSA-9610379;Reactome: R-HSA-983168;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "HCMV Late Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" XP_050308413.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_050310734.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_050294253.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)" XP_050302695.1 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_050293115.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050305984.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311982.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304487.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050303252.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_050294517.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050308870.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050303284.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050310332.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050295831.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050314035.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050311973.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303881.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation" XP_050311296.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050308346.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_050294455.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050309919.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050316285.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050314360.1 3 MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456 "Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid" XP_050295537.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_050295949.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050301690.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050306868.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_050304196.1 4 MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27 "2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_050314041.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_050307223.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050303281.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport" XP_050296208.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050304966.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050314732.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050304665.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050315073.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_050292992.1 12 Reactome: R-HSA-399719;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8 "Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism" XP_050308119.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_050294919.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_050297076.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244 "HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation" XP_050292956.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_050303454.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_050303383.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" XP_050298923.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050299717.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050299450.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_050306651.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA" XP_050300849.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_050316304.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_050308178.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX" XP_050296532.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050299897.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050301733.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_050306157.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050302554.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050300150.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050302391.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050310598.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;MetaCyc: PWY-7511 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination" XP_050309141.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050309902.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050312002.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050312396.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050305523.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_050293058.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_050299995.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_050297557.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_050310756.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050307530.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050312161.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050306875.1 11 Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition" XP_050306696.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)" XP_050311330.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_050308541.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333 "HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_050315575.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_050311980.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050297357.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_050294514.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050298171.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_050296394.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050296244.1 9 Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507 "Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation" XP_050299800.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050296768.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050301140.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050314626.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050316383.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_050300448.1 9 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_050298753.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050297553.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050310256.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050302494.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050314706.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_050308753.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050296142.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050305727.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_050316172.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_050316322.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050314103.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050296578.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_050307036.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_050305462.1 10 MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7661;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_050292974.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050309534.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_050303019.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_050308524.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050294874.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115 "Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_050308191.1 26 Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9617629 "NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation" XP_050293956.1 16 Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_050304436.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_050294547.1 17 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Thermogenesis" XP_050311876.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_050298454.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050293151.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050311724.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050302253.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050292855.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050301384.1 24 KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5607764 "PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"RSK activation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Integrin signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling" XP_050306374.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_050292883.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885 "snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins" XP_050297250.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_050303360.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050311772.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_050294071.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050309113.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_050296953.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050314800.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050295303.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050304110.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_050316266.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050314848.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050309800.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050299405.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_050304241.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex" XP_050308190.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-210744 "Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_050302409.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050312442.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050306360.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050303271.1 19 Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-983231 "Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate PAKs";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"EGFR downregulation";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"Myogenesis";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production" XP_050302173.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050312930.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050306706.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050305231.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050294876.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050313071.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050311206.1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" XP_050313696.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_050293320.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050303640.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050302469.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050312521.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_050294216.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050304171.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050293980.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050307049.1 12 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-1169408 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism" XP_050296544.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_050303586.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050310854.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_050299320.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050299741.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_050313239.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_050296602.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_050302261.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_050312505.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050304200.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_050311411.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050312452.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_050304259.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)" XP_050310064.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_050295162.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_050313488.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050303929.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050303228.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050307794.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_050314196.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050315928.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_050314028.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050299732.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_050297569.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300141.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050313363.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050313283.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050293990.1 9 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1" XP_050297003.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099 "Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling" XP_050312532.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050305815.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine" XP_050307107.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050304548.1 2 KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_050301358.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050312462.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050304370.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_050314584.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_050298901.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050306891.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050307077.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050297197.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050310877.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050313805.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050310555.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_050306905.1 13 Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538 "Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI" XP_050297669.1 8 Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263 "Asymmetric localization of PCP proteins";"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination" XP_050293506.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_050301441.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2" XP_050309285.1 5 KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7204 "Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)" XP_050298178.1 57 Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837 "Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation" XP_050310611.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050306377.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_050305153.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_050314943.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation" XP_050300796.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050307327.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148 "RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050295346.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050308646.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050307273.1 8 MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633 "Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_050311298.1 1 MetaCyc: PWY-6771 "Rhamnogalacturonan type I degradation II (bacteria)" XP_050296950.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050307968.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050311900.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050307092.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_050310879.1 3 Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60 "Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation" XP_050294031.1 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" XP_050301752.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050297593.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159227 "SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA" XP_050303353.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_050311422.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050313620.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_050310308.1 6 MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10 "UMP biosynthesis II";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism" XP_050294157.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050316292.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050308579.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_050294073.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050307030.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050298386.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_050308079.1 3 Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050307708.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050302571.1 15 Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944 "Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2" XP_050303983.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050314058.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_050298123.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-9018519 "RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Estrogen-dependent gene expression" XP_050309483.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_050305726.1 4 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-6783310;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Fanconi Anemia Pathway";"Depolymerisation of the Nuclear Lamina" XP_050295648.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050301026.1 8 KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_050312852.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_050314658.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050293503.1 10 Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704 "Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Phosphatidylinositol signaling system";"PI3K Cascade" XP_050311019.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_050302206.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080 "Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)" XP_050307960.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050309173.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050293187.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050305768.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050305119.1 19 MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-70263 "Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis" XP_050315757.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050312975.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050311127.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050316390.1 13 KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II" XP_050315008.1 4 Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_050300400.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_050298976.1 18 Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism" XP_050299677.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050308666.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050314014.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050306373.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_050302720.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_050313206.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_050313344.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050294022.1 10 KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism" XP_050316360.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_050299557.1 15 Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579 "Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange" XP_050314559.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050297136.1 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" XP_050304380.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_050310098.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050293362.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_050303593.1 18 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72706 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050302101.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050300443.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050294456.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050315076.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_050296812.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_050313934.1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275 "Regulation of TLR by endogenous ligand";"VLDL clearance";"LDL remodeling";"Scavenging by Class B Receptors";"LDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron assembly";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation" XP_050298748.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050314034.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050315302.1 6 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980 "Cristae formation";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis" XP_050299734.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_050302703.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_050311147.1 8 MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_050292748.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050296088.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050301463.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_050298572.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050315636.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050304012.1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion" XP_050312181.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050295190.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050296451.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_050308006.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050305364.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050311582.1 4 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_050306376.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_050299725.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050308765.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress" XP_050306101.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_050309343.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050305850.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_050306610.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_050302030.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_050309920.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050315831.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050293755.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_050292985.1 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_050316213.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" XP_050303906.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_050312303.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_050306765.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050307303.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050311995.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305748.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050310883.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_050296611.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_050304592.1 6 KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;MetaCyc: PWY-6363 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_050314295.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_050311379.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050315150.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_050306815.1 14 Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400 "Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER" XP_050296389.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050310424.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_050315841.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050302404.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050315829.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050306030.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_050300022.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_050306900.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050301651.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_050308701.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311216.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_050293467.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_050294032.1 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" XP_050301626.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050315146.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050297439.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_050310375.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276 "Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_050295163.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_050313558.1 6 MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952 "Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_050303499.1 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_050296748.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_050313719.1 5 KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_050312857.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050309030.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050301104.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050303240.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050299437.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050293713.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050310671.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA" XP_050306506.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050308145.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_050298138.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050300248.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_050310875.1 20 MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_050294935.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050305830.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050297178.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_050308224.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_050293457.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050305386.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050311962.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050310111.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050296947.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050295761.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_050300940.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952 "Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation" XP_050292755.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_050309827.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_050303923.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050308640.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050297688.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination" XP_050300919.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050313695.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_050315125.1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" XP_050298666.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050293319.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050306184.1 4 KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_050306371.1 6 KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004 "Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I" XP_050299720.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050299129.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050308344.1 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis" XP_050305236.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050308660.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050304793.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050297574.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303404.1 4 Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781 "tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis" XP_050314452.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_050302453.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221 "Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway" XP_050309598.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_050305874.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050301015.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling" XP_050296380.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050301596.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_050306766.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_050312747.1 3 Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050294951.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_050302007.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_050307706.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050314649.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050309830.1 11 MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_050293873.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050300776.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_050310261.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050313241.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_050311961.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304891.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_050293451.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_050316319.1 4 KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" XP_050308675.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_050295545.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_050311857.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050304815.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_050295737.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic" XP_050293596.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050292977.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050305372.1 12 MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_050294080.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050314772.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_050293937.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854 "Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis" XP_050302534.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050305644.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_050312384.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050308783.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050305151.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_050304041.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_050311808.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_050315362.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_050306480.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050305081.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_050315483.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_050312826.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_050296594.1 22 MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_050303029.1 8 KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1 "Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_050315627.1 20 KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-6728;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_050294478.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_050308911.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050307610.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050302050.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050316180.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050294030.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_050296134.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050295321.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_050305103.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_050311787.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050316260.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050301539.1 10 MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112 "Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification" XP_050294146.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_050298928.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism" XP_050306515.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050295538.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_050294847.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_050298369.1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944 "Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2" XP_050298021.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_050294312.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_050315056.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_050296021.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050300326.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_050293852.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC" XP_050304176.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050299601.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050302733.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050309213.1 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_050307742.1 11 Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_050293593.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_050300010.1 10 KEGG: 00710+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042 "Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)" XP_050294978.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050307272.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895 "MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis" XP_050303035.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050295786.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050305980.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050294057.1 5 MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3 "Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"One carbon pool by folate" XP_050304082.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_050302792.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_050310372.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_050311887.1 9 Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142 "Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_050306828.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050299596.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050306941.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_050303265.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_050296049.1 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6 "Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism" XP_050303381.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" XP_050306382.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_050296581.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_050306034.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050310758.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050309912.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_050307853.1 8 MetaCyc: PWY-5723;Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6 "Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_050305925.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050311091.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_050293652.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050309626.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_050294794.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" XP_050302322.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_050311682.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_050310171.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050299787.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_050306263.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050301144.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050312721.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050315629.1 20 KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-6728;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_050298370.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-9022692 "Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity" XP_050302064.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050306262.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050314086.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050308707.1 7 KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980 "Photosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis" XP_050303714.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_050308060.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_050312256.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_050309540.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050311965.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304102.1 3 KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_050316303.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_050308827.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_050296307.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050306537.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763 "Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction" XP_050295988.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_050301451.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050301065.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_050307627.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050296254.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050293401.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050312790.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050298111.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050301480.1 6 Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_050299261.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050295625.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050305490.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_050293289.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_050311173.1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" XP_050297507.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050314453.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050306663.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167290 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation" XP_050309896.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_050292694.1 57 Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939236 "Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_050307797.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050295587.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050296107.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050307474.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_050297067.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050304322.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_050315776.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_050315971.1 14 Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985 "EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Nuclear signaling by ERBB4" XP_050293203.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050299783.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050294713.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050302277.1 5 KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201 "One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I" XP_050307889.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_050307112.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050304848.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_050305415.1 3 Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45 "Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism" XP_050296139.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050308650.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050309234.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Plasmalogen biosynthesis" XP_050307458.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_050292920.1 9 Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400 "Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER" XP_050306481.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050306029.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_050293774.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_050311371.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050294708.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050292814.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050297559.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507 "Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation" XP_050294878.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050307228.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050294637.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050298712.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_050314511.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_050314321.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_050302610.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050293644.1 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_050305780.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050295017.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690 "HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events" XP_050297709.1 9 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule" XP_050315770.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050294638.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050315206.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050295090.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050315959.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_050315827.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050309739.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_050302038.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050298909.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050296033.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_050305965.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050303519.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050315057.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_050311521.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_050298231.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050303169.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050294809.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050307574.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050314151.1 5 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172 "p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions" XP_050305461.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050307746.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050302081.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_050315187.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050313804.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050312152.1 5 Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408 "RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism" XP_050313886.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-9610379 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"HCMV Late Events" XP_050301919.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050311493.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_050298918.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050311827.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_050304653.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050292785.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_050307626.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050312201.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050311349.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941 "Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses" XP_050299740.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_050310633.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_050299266.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_050310909.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_050304559.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_050310612.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_050313280.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_050296116.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294453.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050313114.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_050308197.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050307005.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050307877.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050311536.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050300964.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_050309277.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_050310552.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II" XP_050308153.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050315565.1 5 Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_050312102.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050308658.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_050296946.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050299130.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050310780.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_050310334.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_050308092.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050295731.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050296384.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050295307.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050306296.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402 "Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex" XP_050295576.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_050301385.1 24 Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-5607764;Reactome: R-HSA-202424 "VEGFR2 mediated cell proliferation";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"RHO GTPases activate PKNs";"Activation of AKT2";"Integrin signaling";"VEGFR2 mediated vascular permeability";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling" XP_050300568.1 4 MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis" XP_050306571.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050307074.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050296954.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050305873.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050300352.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_050315669.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_050309894.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange" XP_050313364.1 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling" XP_050292919.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER" XP_050312495.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050311758.1 12 KEGG: 04660+3.1.3.16;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-9648025;Reactome: R-HSA-400253;Reactome: R-HSA-68877;KEGG: 04658+3.1.3.16;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788 "T cell receptor signaling pathway";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"EML4 and NUDC in mitotic spindle formation";"Circadian Clock";"Mitotic Prometaphase";"Th1 and Th2 cell differentiation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling" XP_050294482.1 4 KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III" XP_050297472.1 12 Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817 "Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Stachyose degradation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen synthesis";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050294738.1 7 KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67 "Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_050297000.1 56 Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276 "Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_050298964.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050296899.1 8 MetaCyc: PWY-7734;MetaCyc: PWY-7765;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7733;KEGG: 00380+3.5.1.9 "Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Tryptophan metabolism" XP_050296820.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050308158.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_050304937.1 10 MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis" XP_050305682.1 2 Reactome: R-HSA-3322077;Reactome: R-HSA-3785653 "Glycogen synthesis";"Myoclonic epilepsy of Lafora" XP_050306655.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_050305739.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050298375.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496 "Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs" XP_050310399.1 10 KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6536;Reactome: R-HSA-916853;MetaCyc: PWY-6535;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19 "Butanoate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"Degradation of GABA";"4-aminobutanoate degradation I";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV";"Propanoate metabolism" XP_050302257.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050296263.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_050309953.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597 "Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events" XP_050299784.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050305385.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050302963.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050304277.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050314248.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050304058.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_050300815.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_050301988.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050309611.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050311158.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_050293466.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_050303067.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_050303150.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050304549.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_050295309.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_050302753.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_050313421.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050299451.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050316111.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_050312296.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_050308901.1 4 Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_050314152.1 5 Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638 "DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway" XP_050313836.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_050305502.1 8 Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16 "Synthesis of PG";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation" XP_050298453.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_050294477.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_050299505.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050309637.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050312413.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050294626.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050295790.1 4 Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_050311095.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism" XP_050315976.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050301634.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050316148.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257 "Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN" XP_050296096.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294512.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050296367.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050306229.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459 "NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050298302.1 18 Reactome: R-HSA-72695;Reactome: R-HSA-6791226;KEGG: 00970+6.1.1.1;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-379726;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Aminoacyl-tRNA biosynthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Mitochondrial tRNA aminoacylation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050298895.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_050309595.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209 "AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_050298124.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression" XP_050307212.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050306035.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_050309530.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050302663.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050300251.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361 "Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins" XP_050308207.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050299152.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050311367.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050307308.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport";"Neddylation" XP_050308093.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050296579.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_050299721.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050312390.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050294758.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050307478.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050303253.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_050297265.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895 "MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis" XP_050304923.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_050307903.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_050296949.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050311406.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050310118.1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050301258.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050312508.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_050299898.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050308808.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_050306601.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_050310755.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition" XP_050307191.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_050294950.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_050316115.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_050296767.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050296227.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_050314039.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_050312746.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_050300000.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_050314888.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050298278.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050315671.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050300291.1 3 Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6" XP_050315012.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050296528.1 4 MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383 "Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_050294717.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050292837.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_050314578.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050307226.1 25 Reactome: R-HSA-8939902;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8939256;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8936459;Reactome: R-HSA-8941284;Reactome: R-HSA-8951936;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8941858;Reactome: R-HSA-8939243;Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8951911;Reactome: R-HSA-8939246;Reactome: R-HSA-8941332 "Regulation of RUNX2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"Regulation of RUNX3 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration" XP_050309089.1 18 MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925 "Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG" XP_050315042.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050294325.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050316121.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050314935.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_050296390.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050315214.1 13 Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-5689877 "HSF1 activation";"Aggrephagy";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs" XP_050308072.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_050297657.1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" XP_050300211.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_050300369.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-166208 "mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling" XP_050306307.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_050310119.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_050303485.1 6 Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_050300801.1 12 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway" XP_050304753.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_050314595.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_050306845.1 16 Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631 "Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility" XP_050310210.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_050308872.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_050303020.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_050312507.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_050305017.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_050309528.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_050305934.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050293393.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050302487.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050313319.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_050304444.1 10 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_050297580.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_050300824.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050306504.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050299952.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_050303894.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_050304252.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex" XP_050314440.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_050299305.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050300717.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050293008.1 8 Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736 "Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors" XP_050295809.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050301260.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050310272.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050297108.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation" XP_050295447.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_050302414.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050311957.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050293578.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050307069.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050309578.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050293688.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050308656.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050293895.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_050304319.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601 "Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_050293646.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_050303872.1 3 KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246 "Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I" XP_050314204.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050302513.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050305673.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_050293011.1 4 Reactome: R-HSA-2672351;MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Stimuli-sensing channels";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_050312441.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_050311132.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050294072.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050299575.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050309366.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation" XP_050296343.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_050313787.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050308647.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050301951.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_050292772.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050299498.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050303093.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050300780.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050308996.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050299371.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050302994.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050312387.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_050298019.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050306545.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway" XP_050305986.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050296174.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050315316.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050301544.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_050298843.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050314646.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_050314583.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050295403.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050309501.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050314284.1 5 MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37 "Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_050312268.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050309539.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050297176.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis" XP_050304195.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_050297547.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050307572.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_050299168.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_050300872.1 6 Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_050305167.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_050294955.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_050292857.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050316274.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050295807.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050313613.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050307323.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_050312480.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_050303917.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050302555.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_050293399.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253 "FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex" XP_050301987.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050300877.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_050310225.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050312931.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050311723.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050295228.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050297840.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050311776.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050297334.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050293872.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050302406.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050293316.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_050296671.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050299589.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_050310255.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050302421.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050308952.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_050305868.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050314029.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_050299966.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050307164.1 18 KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1 "Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_050315105.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050315010.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases" XP_050308969.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_050296976.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_050313650.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_050302012.1 11 Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation" XP_050296109.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304806.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_050309514.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050309191.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509 "Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes" XP_050298907.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_050314040.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_050313420.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_050311399.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050311383.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050307729.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_050301583.1 4 Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695 "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Neutrophil degranulation" XP_050306390.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695 "Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation" XP_050292762.1 6 Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_050298555.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_050295548.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050307904.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050312001.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050307791.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050315900.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050298602.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_050307897.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050312007.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050297802.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930 "G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor" XP_050298536.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050304092.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050296255.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" XP_050301439.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_050295688.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport" XP_050295595.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050309384.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050310551.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411 "Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere" XP_050301885.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_050316066.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_050310183.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050307770.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_050299974.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050310314.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_050311378.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050309533.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050295476.1 7 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_050295848.1 12 MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4 "Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism" XP_050307076.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_050314620.1 3 KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism" XP_050315651.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis" XP_050315502.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050293488.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_050311799.1 15 Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810 "Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII" XP_050307783.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050297579.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305095.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_050313611.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050314146.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_050305708.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050313260.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050293271.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050306792.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050307448.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050307244.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_050312389.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050307047.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408 "ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_050301783.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050307368.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050296022.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050297725.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050297855.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050307305.1 10 KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_050297278.1 9 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-901042 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Calnexin/calreticulin cycle" XP_050315096.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927 "MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis" XP_050315828.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050308445.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050305677.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_050306059.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050303926.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050309579.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050310260.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050304199.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_050295204.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism" XP_050296952.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050315935.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_050307948.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_050300489.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050301519.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657 "ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes" XP_050302396.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050300745.1 15 Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519 "Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression" XP_050295230.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050311299.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050296661.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050313802.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050307957.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050308700.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050314934.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695 "Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation" XP_050306068.1 34 Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236 "NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"RHO GTPases Activate Formins";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050305130.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050306707.1 60 MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;Reactome: R-HSA-1482798;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5177;Reactome: R-HSA-77305;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6435;Reactome: R-HSA-77350;Reactome: R-HSA-77285;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-7778;MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;Reactome: R-HSA-77348;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-5789;MetaCyc: PWY-1361;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5138;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77310;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17+1.1.1.35 "Fatty acid salvage";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Fatty acid degradation";"Acyl chain remodeling of CL";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Benzoate degradation";"Glutaryl-coa degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Caprolactam degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Tryptophan metabolism";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"Fatty acid elongation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Lysine degradation";"Tryptophan metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"Geraniol degradation" XP_050308837.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_050303075.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050294245.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050301627.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_050313236.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" XP_050299169.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_050298783.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050312681.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_050310286.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_050304424.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_050297565.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313514.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_050307274.1 5 KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III" XP_050314143.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050305743.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050308645.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050312849.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050308061.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_050311020.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_050301887.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_050306653.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_050309473.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_050303595.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050305036.1 13 MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7410 "Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis" XP_050303548.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050315061.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050314220.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050301561.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168333 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"RHO GTPases Activate Formins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_050296589.1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-75815 "Separation of Sister Chromatids";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D" XP_050302209.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050295247.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_050313536.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050296710.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_050298545.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_050297315.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_050311385.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050310307.1 6 Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I" XP_050305020.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_050302401.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050309300.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_050303339.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_050297661.1 14 MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201 "Folate polyglutamylation";"Cyanoamino acid metabolism";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine betaine degradation I";"Methane metabolism";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate transformations I" XP_050295248.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_050293946.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_050303077.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050305832.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050314193.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050316041.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_050297064.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050299212.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050314433.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_050301335.1 6 Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_050315102.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050303933.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050306044.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-168315 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Inhibition of Host mRNA Processing and RNA Silencing" XP_050314813.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856828 "Nef Mediated CD8 Down-regulation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis" XP_050315480.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_050303486.1 6 KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_050303777.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050299284.1 10 MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-6527 "D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation" XP_050316321.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050292999.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules" XP_050301750.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_050309453.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_050306622.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_050297877.1 2 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_050310705.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_050310678.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_050315238.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_050311044.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_050294993.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_050299590.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_050304644.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_050313284.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_050302657.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050310087.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050303190.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport" XP_050292726.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050315888.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050306781.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" XP_050308749.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_050306809.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_050316164.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_050316259.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_050300729.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050303368.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_050307221.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_050297656.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050302633.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050305806.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_050304816.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050309395.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_050293808.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050304254.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398 "RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway" XP_050311677.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_050312199.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050301510.1 29 Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-77075 "RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE" XP_050298365.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_050301888.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_050308448.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_050313259.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050314716.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050295255.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events" XP_050305351.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_050301949.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_050314942.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695 "Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation" XP_050303193.1 11 Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-391160;Reactome: R-HSA-210990 "Platelet sensitization by LDL";"PD-1 signaling";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Signal regulatory protein family interactions";"PECAM1 interactions" XP_050313843.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_050303888.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050311524.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_050308377.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050299369.1 4 MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688 "L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism" XP_050305026.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_050312070.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050309951.1 14 MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)" XP_050298752.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050314267.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_050302070.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050298787.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_050305928.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325 "SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis" XP_050308495.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050315376.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_050297603.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050295451.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050308823.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_050292826.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482839 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE" XP_050311598.1 4 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_050309859.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_050316091.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_050316192.1 7 KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_050302016.1 12 Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985 "EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_050306106.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_050307954.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_050305007.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_050293481.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_050306735.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050292959.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_050292964.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050307896.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_050314194.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050302201.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176412 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C" XP_050314083.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696394 "Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER" XP_050306540.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_050300811.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation" XP_050310677.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_050303018.1 2 Reactome: R-HSA-5627123;Reactome: R-HSA-8856828 "RHO GTPases activate PAKs";"Clathrin-mediated endocytosis" XP_050300286.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178 "CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_050298324.1 10 Reactome: R-HSA-1855167;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;MetaCyc: PWY-6365;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6366;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159 "Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system" XP_050302685.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050311073.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_050294059.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050304339.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_050313753.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_050301386.1 24 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Integrin signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"RSK activation";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_050310088.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050311866.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_050300203.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_050296727.1 26 Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Kinesins";"Aggrephagy";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins" XP_050306472.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311442.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050309355.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050307598.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_050297130.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_050306869.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_050295534.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050304430.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_050294973.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_050302217.1 7 MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-882 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_050312188.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050293954.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_050302541.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_050307369.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050300147.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050308186.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_050309559.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_050300804.1 12 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"NRAGE signals death through JNK" XP_050296421.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_050302492.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_050316142.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050297729.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050297180.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_050300673.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_050308290.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_050298113.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_050301666.1 18 Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7197 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation" XP_050296974.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050311295.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050296207.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_050295833.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050302664.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050307061.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_050308001.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_050294678.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050311242.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050312069.1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236 "Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_050305737.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050298094.1 5 MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine" XP_050314365.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_050299578.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050296457.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_050303015.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_050307944.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1" XP_050297594.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_050300584.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720 "DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_050299627.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483 "TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs" XP_050307204.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050309340.1 9 KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5 "Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism" XP_050296178.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy" XP_050311998.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050306530.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_050299325.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" XP_050312935.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050307707.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050310773.1 11 Reactome: R-HSA-73776;Reactome: R-HSA-8963888;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-8866423;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"Chylomicron assembly";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"VLDL assembly";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_050294859.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050293778.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_050308550.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-9610379 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"HCMV Late Events" XP_050315772.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_050312430.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050308170.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_050298925.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050308723.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_050307838.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050301800.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_050316261.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050305467.1 17 Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16 "Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation" XP_050305352.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_050300812.1 11 Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660 "Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway" XP_050296809.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_050309023.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" XP_050305482.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050304276.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "Syndecan interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_050314804.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_050307543.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_050301373.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_050312151.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050314746.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_050294481.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" XP_050293009.1 4 MetaCyc: PWY-6829;Reactome: R-HSA-2672351;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"Stimuli-sensing channels";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_050304325.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_050316217.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050294299.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050295440.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_050299153.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050314718.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_050304396.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050307622.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050299583.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050300144.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050302731.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050307057.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_050295825.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_050303512.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604 "Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling" XP_050299482.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050306403.1 14 MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1 "Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Oxidative phosphorylation" XP_050303078.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050301522.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657 "ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes" XP_050306608.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_050298028.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_050307730.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)" XP_050311629.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050308192.1 26 Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158 "Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor" XP_050308333.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050298756.1 7 Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" XP_050293777.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_050316256.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_050314239.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_050312449.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_050313573.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity" XP_050311878.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_050304554.1 22 MetaCyc: PWY-5384;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8013;MetaCyc: PWY-7347;MetaCyc: PWY-5514;MetaCyc: PWY-621;KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-6142;MetaCyc: PWY-622;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-6992;MetaCyc: PWY-7385;KEGG: 00010+5.3.1.9;Reactome: R-HSA-6798695 "Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"Pentose phosphate pathway";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch biosynthesis";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"1,5-anhydrofructose degradation";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Neutrophil degranulation" XP_050296035.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_050305255.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_050300754.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050308820.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_050305681.1 2 Reactome: R-HSA-3785653;Reactome: R-HSA-3322077 "Myoclonic epilepsy of Lafora";"Glycogen synthesis" XP_050310271.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050313939.1 7 MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695 "Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation" XP_050308869.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_050307609.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_050306366.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050294495.1 31 MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-5147;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-6282 "(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Biotin metabolism";"";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" XP_050313091.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050300099.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050310042.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050308654.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_050312350.1 4 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_050304706.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050295667.1 8 Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-917977 "Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling" XP_050310457.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_050298104.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_050313937.1 17 MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765 "Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression" XP_050300544.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_050314062.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050298004.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_050297973.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050310386.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I" XP_050298640.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050303138.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050311116.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050296103.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050314249.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_050296052.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050298978.1 18 MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4 "Plasmalogen degradation";"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Arachidonic acid metabolism" XP_050295832.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050313944.1 17 MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1 "Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Pyruvate metabolism";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_050308292.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050299262.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_050311421.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050295205.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_050304999.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_050314826.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_050295233.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050315555.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050315604.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_050313766.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050306159.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050310818.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978 "Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"UCH proteinases";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_050303909.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" XP_050296573.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_050304587.1 11 MetaCyc: PWY-7124;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6549 "Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"Methylaspartate cycle";"L-glutamine biosynthesis III" XP_050294258.1 14 MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5101 "L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II" XP_050297602.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050309342.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050296817.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050310024.1 5 KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4 "Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies" XP_050293507.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_050302384.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)" XP_050316355.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050307834.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050306362.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_050301042.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_050306304.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-912446 "Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination" XP_050300127.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050303862.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050297706.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_050302644.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050301758.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050306236.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_050311888.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_050295094.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050311991.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050299758.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709 "N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins" XP_050293413.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050299281.1 10 Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977 "Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)" XP_050310252.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_050314075.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_050297957.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_050314642.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_050297256.1 3 KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5 "Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism" XP_050302300.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050303995.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_050301499.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_050292727.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_050296639.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050295909.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050311368.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050297174.1 6 Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050297429.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050313472.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050296087.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311130.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050295126.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins" XP_050296204.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5674400 "Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer" XP_050314643.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_050295729.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050294829.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_050298132.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050295036.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_050316242.1 18 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat" XP_050310450.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050306022.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_050313357.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_050308000.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_050308614.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050299982.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050306134.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050299177.1 20 Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1 "Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"HSF1-dependent transactivation";"Macroautophagy";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis" XP_050303916.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050297438.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_050311879.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_050316228.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050301737.1 30 Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167161 "Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation" XP_050293093.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_050308400.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_050307108.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_050303023.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050305383.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050313235.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050292718.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_050302242.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases" XP_050304014.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_050315494.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_050298279.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050314802.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_050306275.1 5 Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-1234158 "PTK6 Expression";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"Regulation of gene expression by Hypoxia-inducible Factor" XP_050295698.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050315114.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050294060.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_050312722.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_050311893.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_050310601.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_050293996.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050309177.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050297822.1 14 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition" XP_050302266.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_050292735.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_050312180.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050306757.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_050295965.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7659 "(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis" XP_050311208.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050316311.1 5 Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361 "Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050308687.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation" XP_050308761.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050300582.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events" XP_050294594.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050304054.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050306309.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050311613.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_050305015.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production" XP_050293508.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_050296747.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_050295840.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400 "Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER" XP_050302017.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_050312859.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_050298131.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_050301257.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050297597.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050310915.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_050307599.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_050307238.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_050304447.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_050308633.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_050299064.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050314046.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_050293350.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050294764.1 11 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-5689880 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases" XP_050310066.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_050308357.1 17 Reactome: R-HSA-111448;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-69202 "Activation of NOXA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition" XP_050315748.1 33 Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953 "Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation" XP_050312360.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_050298404.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_050310681.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_050309610.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050311446.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050297711.1 9 MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-416476 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events" XP_050310086.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050308314.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-9609523;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Cargo concentration in the ER";"Intra-Golgi traffic";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_050308721.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_050299780.1 6 KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_050301409.1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_050306380.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_050306102.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_050294431.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events" XP_050312967.1 24 Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-9634600;Reactome: R-HSA-5621575;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-4420097;Reactome: R-HSA-8853659;Reactome: R-HSA-5687128;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610783;Reactome: R-HSA-422356;Reactome: R-HSA-442720;Reactome: R-HSA-5610780;Reactome: R-HSA-9010642;Reactome: R-HSA-5610785;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163358;Reactome: R-HSA-111931;Reactome: R-HSA-163615 "Rap1 signalling";"PKA activation in glucagon signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CD209 (DC-SIGN) signaling";"HDL assembly";"Triglyceride catabolism";"VEGFA-VEGFR2 Pathway";"RET signaling";"MAPK6/MAPK4 signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI1 by the proteasome";"ROBO receptors bind AKAP5";"GLI3 is processed to GLI3R by the proteasome";"mTOR signaling pathway";"PKA-mediated phosphorylation of key metabolic factors";"PKA-mediated phosphorylation of CREB";"PKA activation" XP_050302561.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_050315628.1 20 KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-75105 "Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis" XP_050304947.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050307165.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_050307302.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050313082.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050314030.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_050306502.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_050307652.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_050306063.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050302756.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_050294045.1 10 MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis" XP_050296115.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305783.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172 "Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome" XP_050307581.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-216083 "Laminin interactions";"Anchoring fibril formation";"Collagen chain trimerization";"Collagen degradation";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Signaling by PDGF";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions" XP_050315072.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_050309890.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050296935.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_050302111.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_050293868.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050309849.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_050298749.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050312618.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050296287.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050314174.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050300277.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050304500.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050301222.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_050303490.1 10 KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695 "Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation" XP_050298675.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_050306856.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_050295305.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050306930.1 14 Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169 "Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis" XP_050312416.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050310519.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_050310806.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_050299680.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_050314172.1 5 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism" XP_050315131.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050305150.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_050300517.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1 "PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism" XP_050305926.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-4085377 "SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins" XP_050303114.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050300030.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport" XP_050312184.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050298269.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_050292972.1 12 Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules" XP_050295672.1 14 Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4 "Synthesis of PC";"Synthesis of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism" XP_050311931.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050308260.1 4 Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255 "HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis" XP_050314067.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050293372.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_050307025.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_050294582.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_050294890.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050303843.1 3 Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_050292711.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_050293971.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210 "PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_050298894.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_050300477.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050309319.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050300931.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_050302394.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050297581.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_050307713.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050307276.1 5 MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050299593.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_050294470.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_050296743.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_050309763.1 18 KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1 "Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis" XP_050300006.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_050296772.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_050296441.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_050315566.1 5 KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006 "Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_050314292.1 5 Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558 "PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_050304352.1 14 Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638 "NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_050299431.1 24 Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-6814122 "Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_050305053.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" XP_050304969.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050295311.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_050295229.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_050298039.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050310520.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_050315476.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_050313785.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050313965.1 5 MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_050295185.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050298310.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_050315970.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_050310227.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_050292975.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050301388.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_050304551.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_050293400.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_050300669.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_050296917.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_050306913.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_050301218.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_050298114.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" XP_050303546.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050299183.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_050293829.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_050298273.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050297573.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050304338.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_050293266.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_050312831.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_050312231.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050294428.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_050301458.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050311790.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_050293875.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050308189.1 26 Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300 "Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"SUMOylation of transcription cofactors" XP_050311881.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_050307364.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050305165.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050314015.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_050301143.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050312939.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_050311605.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-8940973 "Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation" XP_050294838.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_050298807.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050294795.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050316362.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_050308740.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962 "Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex" XP_050311794.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_050314868.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_050309988.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_050303081.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_050308661.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_050309955.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787 "PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state" XP_050308988.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050302659.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_050307947.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1" XP_050303498.1 4 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_050298893.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050308312.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_050314880.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050303254.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_050297972.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_050299891.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_050307806.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050296720.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_050301392.1 6 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism" XP_050311301.1 10 Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069 "Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity" XP_050304226.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050311867.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_050294474.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_050304869.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_050305250.1 20 MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-5136 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)" XP_050300867.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_050299499.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981 "Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III" XP_050314879.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_050315468.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_050308204.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050308873.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_050303196.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409 "Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis" XP_050297613.1 10 KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7199;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"Folate transformations II (plants)" XP_050299331.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_050307971.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050300808.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_050305163.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_050297724.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_050313762.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_050303382.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6" XP_050310268.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050305016.1 3 Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway" XP_050304111.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events" XP_050302922.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_050310022.1 7 KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4 "Geraniol degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Synthesis and degradation of ketone bodies" XP_050304137.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050312351.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050298374.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398 "Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway" XP_050309201.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_050306785.1 21 MetaCyc: PWY-7220;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7219;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_050315336.1 42 Reactome: R-HSA-110330;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-110328;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-201722 "Recognition and association of DNA glycosylase with site containing an affected purine";"Estrogen-dependent gene expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Meiotic recombination";"DNA methylation";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex" XP_050307469.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_050314303.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_050305847.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_050312135.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_050310735.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport" XP_050314665.1 5 MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18 "Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism" XP_050304016.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_050305896.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_050295990.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_050294158.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_050310043.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_050312697.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_050301420.1 6 KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22 "Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism" XP_050312003.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050300039.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_050310823.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_050303670.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_050312417.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_050304318.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis" XP_050295622.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_050300802.1 12 Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "NRAGE signals death through JNK";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_050314076.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_050307831.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_050311432.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532 "TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_050296166.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691 "T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling" XP_050315542.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_050301494.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050297571.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050301652.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_050308494.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_050294808.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_050304117.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins" XP_050312341.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050300728.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050293236.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_050306621.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_050311354.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_050312369.1 3 Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420 "Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)" XP_050309605.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050308763.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress" XP_050311746.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol" XP_050293951.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_050306091.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050314085.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER" XP_050311328.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway" XP_050310874.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_050311178.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050297881.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_050296118.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050313422.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050310075.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050307755.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050296079.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_050309502.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_050308200.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050305460.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_050311743.1 14 Reactome: R-HSA-1474151;Reactome: R-HSA-6811438;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;Reactome: R-HSA-204005;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-6811434;MetaCyc: PWY-5663;MetaCyc: PWY-7852;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;MetaCyc: PWY-6983 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Intra-Golgi traffic";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"COPII-mediated vesicle transport";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Threo-tetrahydrobiopterin biosynthesis" XP_050302425.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_050312976.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_050305092.1 10 KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276 "Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)" XP_050313782.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050293112.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_050298788.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_050315275.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050307883.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_050302964.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050308704.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050301731.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_050304834.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_050312830.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782 "CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Plasmalogen biosynthesis" XP_050303583.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_050305533.1 12 Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13 "Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism" XP_050296135.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050305738.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_050312916.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-6803 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing" XP_050297459.1 10 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_050315062.1 18 KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism" XP_050306460.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_050314483.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050310157.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_050314363.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_050300970.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_050310401.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050293732.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_050293500.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_050295785.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_050297668.1 8 Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870 "Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins" XP_050301934.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050308068.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_050300917.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_050309151.1 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" XP_050313149.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_050304101.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" XP_050299062.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050305157.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_050302229.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion" XP_050295925.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050294125.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050294870.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_050305418.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050298510.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050305235.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050309597.1 10 Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483 "Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs" XP_050306971.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_050306313.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_050312739.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_050314047.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_050316023.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_050304139.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_050292957.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_050312848.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_050303092.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_050294437.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_050294029.1 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" XP_050297072.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001 "Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade" XP_050298259.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_050304498.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050308462.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_050305791.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_050303584.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_050313136.1 7 MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25 "Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism" XP_050302400.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_050308677.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_050307972.1 6 Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560 "Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism" XP_050308973.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121 "Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI" XP_050303665.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_050312012.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_050296769.1 9 Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-6470 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_050311997.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050306652.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_050314465.1 6 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_050313715.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_050298228.1 4 KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_050305169.1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_050305512.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_050308155.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_050297118.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-936837 "Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases" XP_050307815.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050301210.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_050314577.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_050302290.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050302656.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins" XP_050298325.1 10 MetaCyc: PWY-6366;MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;Reactome: R-HSA-1855167 "D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol" XP_050313763.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_050307010.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050310073.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_050298754.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050301745.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" XP_050297074.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" XP_050296346.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-9630222 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding" XP_050297666.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_050301333.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_050303882.1 3 Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation" XP_050295371.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_050302670.1 6 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-983168;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion" XP_050312052.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_050304023.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2644606 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050311612.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_050312850.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_050313996.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_050294510.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_050295439.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_050303235.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_050309051.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_050297284.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_050295883.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_050298750.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_050295808.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_050298830.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_050305389.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_050308634.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_050303927.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_050308522.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_050306240.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-241 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_050314896.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_050304513.1 11 Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6538 "Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)" XP_050302721.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_050303920.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_050303553.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_050293807.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_050292995.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_050293869.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_050305694.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050312269.1 10 Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_050304121.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399 "Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy" XP_050308450.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_050311022.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12 "Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms" XP_050309982.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_050308375.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_050299580.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_050298729.1 13 Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"mTOR signalling";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Macroautophagy" XP_050299984.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_050297287.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_050308179.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409 "Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A" XP_050293519.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_050305366.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_050316301.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_050302788.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050311131.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_050313068.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_050312402.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_050311672.1 5 Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)" XP_050315147.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_050307731.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_050315330.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_050301159.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_050310608.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_050301956.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_050297275.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_050314200.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_050309778.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615 "Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation" XP_050301689.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_050296519.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_050301644.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_050299678.1 7 MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4 "Choline biosynthesis III";"Synthesis of PA";"Ether lipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism" XP_050296907.1 8 KEGG: 00630+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7733;MetaCyc: PWY-7734;MetaCyc: PWY-7765 "Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II" XP_050299199.1 7 Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation" XP_050316298.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_050307711.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_050306062.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_050298801.1 10 MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Folate transformations I";"L-histidine degradation III";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes" XP_050305338.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_050314008.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_050314594.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_050314059.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_050304655.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_050312455.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_050300809.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_050303141.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_050297575.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_050299238.1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" XP_050296385.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_050295926.1 13 KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9 "One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate" XP_050296083.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_050315509.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_050305329.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation" XP_050294992.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_05031