Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_050306061.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050295465.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050307788.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050302232.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050309805.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050301980.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_050307555.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050302908.1	4	KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050309688.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050297604.1	5	MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway"
XP_050304397.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050316340.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_050310617.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050303580.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050299625.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897	"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes"
XP_050314894.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050309101.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050314849.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050307985.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050296066.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302660.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050309481.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_050300752.1	5	Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)"
XP_050312858.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050293094.1	32	Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-77075	"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050304580.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050307075.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050299270.1	31	KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-5973;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;Reactome: R-HSA-9029558	"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Biotin metabolism";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050292856.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050315657.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion"
XP_050311681.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050299941.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050314497.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050304591.1	6	MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362	"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_050298271.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050303274.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050305790.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050314198.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050303184.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-114604;Reactome: R-HSA-9008059	"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"GPVI-mediated activation cascade";"Interleukin-37 signaling"
XP_050299326.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_050309592.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050310238.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050303755.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050311567.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050296210.1	9	KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050303128.1	6	KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-7356	"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine salvage IV (yeast)"
XP_050313485.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050305918.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050302182.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050314307.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050304236.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_050308615.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050315142.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_050295569.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050306629.1	3	Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050309463.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050311105.1	12	KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409	"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_050300581.1	8	Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-983231	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production"
XP_050314012.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050297945.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050305877.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050299318.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050315129.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050309594.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050302755.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050293995.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050313928.1	17	Reactome: R-HSA-2426168;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2	"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism"
XP_050293322.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN"
XP_050297821.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050314337.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050297009.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050306793.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050292745.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"Macroautophagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050303364.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I"
XP_050302129.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_050309108.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298975.1	12	KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25;MetaCyc: PWY-5744;MetaCyc: PWY-7294;MetaCyc: PWY-7295;MetaCyc: PWY-6728;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-6969;MetaCyc: PWY-5749;MetaCyc: PWY-7854	"Pyruvate metabolism";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism";"Glyoxylate assimilation";"D-xylose degradation IV";"L-arabinose degradation IV";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Itaconate degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)"
XP_050308961.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050296291.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification"
XP_050316334.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050310743.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_050305870.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050299986.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050312419.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050299763.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050298521.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_050312829.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210	"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Polymerase switching";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050294287.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050295478.1	15	Reactome: R-HSA-167242;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167287	"Abortive elongation of HIV-1 transcript in the absence of Tat";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery"
XP_050295642.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050309798.1	10	MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559	"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway"
XP_050295579.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050305911.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050311491.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050301443.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling"
XP_050312133.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050302412.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050301978.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050303026.1	8	KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_050306949.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050301686.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050310630.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress"
XP_050293023.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050312330.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050301740.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_050304663.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_050308523.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325	"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis"
XP_050293015.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050310449.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050309503.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050310253.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050300873.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes"
XP_050297694.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050295950.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050314898.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050301360.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050306575.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_050302361.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050313575.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050300758.1	6	MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922	"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_050296791.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050307346.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050302014.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307766.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050307324.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_050315852.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050301688.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050305992.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050310706.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050303616.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050299198.1	7	KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12;Reactome: R-HSA-204174	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050309211.1	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050296966.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050303613.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050296552.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050314203.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050294010.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_050304632.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_050302636.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311129.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050313117.1	6	KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241	"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import"
XP_050298323.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050293041.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;Reactome: R-HSA-9022692;Reactome: R-HSA-6804756;Reactome: R-HSA-9648025;Reactome: R-HSA-174178;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2467813;KEGG: 04926+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-68877;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2500257	"Thermogenesis";"RHO GTPases Activate Formins";"Regulation of MECP2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"EML4 and NUDC in mitotic spindle formation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Separation of Sister Chromatids";"Relaxin signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Human papillomavirus infection";"Mitotic Prometaphase";"Human cytomegalovirus infection";"Resolution of Sister Chromatid Cohesion"
XP_050308601.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312222.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_050307455.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050308472.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050309183.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050308624.1	6	Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_050307390.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050305387.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050309297.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050315135.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050305648.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050299997.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_050298361.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050316189.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050295671.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453	"Anandamide biosynthesis I";"Synthesis of PC";"Synthesis of PE";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_050293900.1	6	MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6	"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism"
XP_050294194.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_050303827.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050311565.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_050296816.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050314474.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-512988	"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Rho GTPase cycle";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"RET signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_050298916.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050303080.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050294941.1	2	Reactome: R-HSA-6783984;Reactome: R-HSA-389661	"Glycine degradation";"Glyoxylate metabolism and glycine degradation"
XP_050307768.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050294636.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050301581.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050307147.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050312914.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050300831.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_050293882.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050296956.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050303192.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311126.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050297235.1	4	Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193	"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I"
XP_050295177.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050296707.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298327.1	5	Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050314272.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle"
XP_050309161.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050292825.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE"
XP_050303565.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050316284.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050315327.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050298959.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050315337.1	42	Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-110331;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-5693571;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632	"DNA methylation";"Meiotic recombination";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Cleavage of the damaged purine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HCMV Late Events";"Estrogen-dependent gene expression";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"Nonhomologous End-Joining (NHEJ)";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"Meiotic synapsis"
XP_050311716.1	5	Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050309480.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_050311402.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050306042.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050311374.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050308144.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050313134.1	7	MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724	"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II"
XP_050301917.1	3	KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_050315571.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050307110.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050303046.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604	"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling"
XP_050302097.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-159236	"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050309341.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050308202.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050292852.1	13	MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-2871796;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-202433	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"FCERI mediated MAPK activation";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"Generation of second messenger molecules"
XP_050313767.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050308225.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050314911.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050296276.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050299722.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050306060.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050315922.1	9	Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781	"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression"
XP_050310757.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050309186.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_050299496.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_050304552.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_050314416.1	6	KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780	"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism"
XP_050292807.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050307569.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050304982.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050306858.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050310614.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050308099.1	4	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_050310456.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050306200.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050307405.1	13	MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-8086;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2	"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)"
XP_050298523.1	7	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_050296738.1	4	Reactome: R-HSA-6790901;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-156581	"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation"
XP_050309012.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050292991.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050314641.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050300598.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050295206.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594	"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events"
XP_050299983.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050305257.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050293139.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_050297570.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295578.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050295221.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050297513.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050313288.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050299595.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050294939.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050308856.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050298603.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050293086.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050297175.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_050307779.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
XP_050296128.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300476.1	4	Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_050305895.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050315474.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050307743.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_050314044.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_050305305.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050302565.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050295322.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050295879.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050306737.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050293321.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050312326.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050308613.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294835.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050304350.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050313539.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304135.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_050306458.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050314186.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_050297551.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313869.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050308653.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050300830.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy"
XP_050303928.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050294671.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_050311807.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050298106.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050307691.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_050308453.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050304946.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050314501.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050300094.1	29	Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050306950.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050311778.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050296745.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Methylation"
XP_050300665.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050299656.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050293183.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_050316358.1	7	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050300730.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050301817.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_050307003.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050305729.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050304066.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050304494.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050309618.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050309184.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_050301697.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050312194.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050292824.1	18	Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4	"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism"
XP_050301963.1	2	Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis"
XP_050309667.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050299432.1	24	Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657	"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors"
XP_050310604.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050294239.1	3	MetaCyc: PWY-5996;Reactome: R-HSA-75105;MetaCyc: PWY-5987	"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis"
XP_050300282.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050294479.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050301121.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis"
XP_050308987.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050297360.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050304449.1	10	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends"
XP_050309200.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes"
XP_050310887.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-438066;Reactome: R-HSA-6794361	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Neurexins and neuroligins"
XP_050316229.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050295175.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050294464.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050295854.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050311106.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism"
XP_050309118.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050297927.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_050298920.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050292881.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050316165.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050304450.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_050313617.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293673.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050303025.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism"
XP_050293965.1	8	MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation"
XP_050303658.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050309893.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_050305249.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_050306064.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298408.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050308117.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050313765.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050299226.1	10	Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1	"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Thermogenesis"
XP_050299883.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_050300583.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-180024	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events"
XP_050309966.1	11	MetaCyc: PWY-6964;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis"
XP_050302960.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050299457.1	3	KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403	"Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling"
XP_050304025.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050304011.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050296388.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050305472.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050307840.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050300874.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050315606.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050313139.1	11	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-163680;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050316214.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304553.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-6538;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6608;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Theophylline degradation";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_050308116.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050313079.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_050303747.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050296955.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050308919.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050311975.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306273.1	5	Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234174;Reactome: R-HSA-1234176;Reactome: R-HSA-1234158	"PTK6 Expression";"Neddylation";"Cellular response to hypoxia";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_050298952.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050292774.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050299628.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_050312429.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050298511.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050305322.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050293310.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050297131.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_050314084.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050296391.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050312367.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050301096.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294186.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_050295197.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050301365.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex"
XP_050296744.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050309487.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_050300712.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050314381.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050300963.1	4	Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240	"Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism"
XP_050314082.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_050313666.1	52	Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-6781823;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-167287	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"Formation of TC-NER Pre-Incision Complex";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"HIV elongation arrest and recovery"
XP_050315794.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_050312688.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050294492.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050293052.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050301477.1	6	Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane"
XP_050295122.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050311247.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050315853.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050312692.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050301546.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050296989.1	8	Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-71336	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway"
XP_050304248.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_050302556.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_050304118.1	12	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050295870.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_050299285.1	10	Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397	"Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_050294037.1	10	MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Pentose phosphate pathway"
XP_050304673.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050313135.1	7	KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-5941	"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Sucrose biosynthesis II";"Starch degradation V";"Glycogen degradation II"
XP_050312450.1	6	KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_050310257.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050297018.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050296277.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050304161.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050302150.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949	"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA"
XP_050297097.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_050310074.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050298643.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050306832.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_050295910.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050296023.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050304459.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050308416.1	6	Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952	"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation"
XP_050312974.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050295640.1	3	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA"
XP_050302701.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050304351.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050304804.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050311215.1	2	Reactome: R-HSA-4570571;Reactome: R-HSA-446193	"Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050310980.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050294070.1	22	Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813	"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids"
XP_050311151.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050305735.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050312828.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_050313614.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050300285.1	3	Reactome: R-HSA-8953750;Reactome: R-HSA-73772;Reactome: R-HSA-427389	"Transcriptional Regulation by E2F6";"RNA Polymerase I Promoter Escape";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_050304320.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050304593.1	6	MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183	"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050300063.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation"
XP_050295275.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050299282.1	10	MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism"
XP_050309770.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050313550.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050307190.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050312391.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050295207.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_050315592.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050301028.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050293496.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050310536.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-350054	"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway"
XP_050295828.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311375.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050314334.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050313737.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_050312255.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050311447.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_050313294.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050309861.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050309187.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_050312744.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050306662.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050309102.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050294471.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_050312523.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050304811.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050301161.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_050312401.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050303037.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050302759.1	4	KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16	"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism"
XP_050312163.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050309621.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050308374.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_050305741.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311350.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses"
XP_050300040.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_050307328.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation"
XP_050305878.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050294252.1	4	Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)"
XP_050301119.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050296093.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311614.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050309689.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050304803.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050308858.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050303238.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050304808.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050295623.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050301649.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"UCH proteinases";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)"
XP_050295336.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_050305161.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306748.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex"
XP_050310615.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050311250.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050297189.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050302407.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050300932.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050294400.1	2	MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24	"Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis"
XP_050310263.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050309007.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050311444.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050308130.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333	"HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050294509.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050315767.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050302662.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050294388.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050314747.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050308968.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050307890.1	5	MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050304504.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050294410.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050300698.1	17	MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184	"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050310110.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_050301141.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050306659.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050314779.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050300404.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_050310259.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050311466.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050293490.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050304301.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050312218.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050311376.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050314610.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050309210.1	7	KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25	"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis"
XP_050303449.1	16	MetaCyc: PWY-7124;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-2221;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-6901	"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation"
XP_050298962.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050306176.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050299283.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_050301128.1	3	MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78	"D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system"
XP_050294505.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050294391.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050313129.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"SUMOylation of DNA damage response and repair proteins"
XP_050311659.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050304019.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050309954.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_050315478.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050295071.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050294064.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_050314344.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_050295054.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050296693.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050316024.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050311583.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_050304938.1	16	Reactome: R-HSA-8856825;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-2132295	"Cargo recognition for clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"MHC class II antigen presentation"
XP_050294068.1	22	Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_050293035.1	5	KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7176	"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis"
XP_050310380.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050302395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050303134.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050294971.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050301372.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050295456.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050309474.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050311124.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050315974.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296143.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050310398.1	10	KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-6536;MetaCyc: PWY-5022	"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"L-glutamate degradation IV";"Butanoate metabolism";"Degradation of GABA";"4-aminobutanoate degradation III";"4-aminobutanoate degradation V"
XP_050300355.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050312010.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050311047.1	7	Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050306470.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050296412.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214	"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_050309188.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050311854.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307243.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050312428.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050302842.1	17	Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174437	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand"
XP_050293597.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050293065.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_050297750.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050314617.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050299227.1	10	Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04151+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"PI3K-Akt signaling pathway"
XP_050306728.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_050308065.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050313281.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex"
XP_050306083.1	5	Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-165159	"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTOR signalling"
XP_050303234.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050303113.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050316290.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050299715.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050294834.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050302251.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050297508.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050310626.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050312845.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050304116.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050303918.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050294718.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050294674.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050293025.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050293305.1	15	MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5484;Reactome: R-HSA-70171	"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis"
XP_050304502.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050302392.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050297815.1	83	Reactome: R-HSA-8853659;Reactome: R-HSA-5654695;Reactome: R-HSA-5654688;Reactome: R-HSA-5654712;Reactome: R-HSA-912631;Reactome: R-HSA-9634285;Reactome: R-HSA-983695;Reactome: R-HSA-8851907;Reactome: R-HSA-1963640;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-5654719;Reactome: R-HSA-1250347;Reactome: R-HSA-9034864;Reactome: R-HSA-5654704;Reactome: R-HSA-8875555;Reactome: R-HSA-74751;Reactome: R-HSA-375165;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5654726;Reactome: R-HSA-74749;Reactome: R-HSA-9607240;Reactome: R-HSA-512988;Reactome: R-HSA-9028335;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-9026519;Reactome: R-HSA-8851805;Reactome: R-HSA-186763;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-8865999;Reactome: R-HSA-5655302;Reactome: R-HSA-9645135;Reactome: R-HSA-6811558;Reactome: R-HSA-2428933;Reactome: R-HSA-1839117;Reactome: R-HSA-5654710;Reactome: R-HSA-8875656;Reactome: R-HSA-180292;Reactome: R-HSA-180336;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-8853334;Reactome: R-HSA-2424491;Reactome: R-HSA-9028731;Reactome: R-HSA-8983432;Reactome: R-HSA-1433557;Reactome: R-HSA-5654727;Reactome: R-HSA-1295596;Reactome: R-HSA-5654700;Reactome: R-HSA-2871796;Reactome: R-HSA-5654733;Reactome: R-HSA-389359;Reactome: R-HSA-8856825;Reactome: R-HSA-2730905;Reactome: R-HSA-5654720;Reactome: R-HSA-5654693;Reactome: R-HSA-5654699;Reactome: R-HSA-182971;Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-109704;Reactome: R-HSA-1250196;Reactome: R-HSA-354194;Reactome: R-HSA-210993;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-5654689;Reactome: R-HSA-179812;Reactome: R-HSA-8853338;Reactome: R-HSA-167044;Reactome: R-HSA-2179392;Reactome: R-HSA-5654732;Reactome: R-HSA-2219530;Reactome: R-HSA-1433559;Reactome: R-HSA-6807004;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8875360;Reactome: R-HSA-5655253;Reactome: R-HSA-912526	"RET signaling";"PI-3K cascade:FGFR2";"SHC-mediated cascade:FGFR1";"FRS-mediated FGFR4 signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Overexpressed ERBB2";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"MET activates PI3K/AKT signaling";"GRB2 events in ERBB2 signaling";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"SHC-mediated cascade:FGFR4";"SHC1 events in ERBB4 signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR3";"MET activates RAP1 and RAC1";"Insulin receptor signalling cascade";"NCAM signaling for neurite out-growth";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Signal attenuation";"FLT3 Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK2 signals through PI3K";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"Activated NTRK2 signals through RAS";"MET activates RAS signaling";"Downstream signal transduction";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET activates PTPN11";"Signaling by FGFR1 in disease";"STAT5 Activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-related events triggered by IGF1R";"Signaling by cytosolic FGFR1 fusion mutants";"PI-3K cascade:FGFR3";"MET receptor recycling";"GAB1 signalosome";"SHC1 events in EGFR signaling";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR3 fusions in cancer";"DAP12 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin-15 signaling";"Signaling by SCF-KIT";"Negative regulation of FGFR2 signaling";"Spry regulation of FGF signaling";"FRS-mediated FGFR2 signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR4 signaling";"CD28 dependent Vav1 pathway";"Cargo recognition for clathrin-mediated endocytosis";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR4";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR2";"EGFR downregulation";"Costimulation by the CD28 family";"Signal regulatory protein family interactions";"PI3K Cascade";"SHC1 events in ERBB2 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Tie2 Signaling";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"PI-3K cascade:FGFR1";"GRB2 events in EGFR signaling";"Signaling by FGFR3 point mutants in cancer";"Signalling to RAS";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of KIT signaling";"Negative regulation of MET activity";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR2 in disease";"Interleukin receptor SHC signaling"
XP_050310748.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050306168.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050304295.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050312394.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050295882.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_050311805.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050305897.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050315768.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050293591.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050305996.1	4	KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193;Reactome: R-HSA-4551295	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_050296090.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303115.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050314106.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050297217.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I"
XP_050295868.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050312204.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050304010.1	24	Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833	"Aggrephagy";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly"
XP_050313119.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050311023.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
XP_050302387.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050304952.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050308748.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050299647.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050302543.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_050314890.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050309322.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050296121.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313443.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050296104.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301950.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050310077.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050296766.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050301637.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050310011.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050301452.1	16	Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700	"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050297229.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050303258.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050308471.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_050302215.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_050302193.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050310331.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731	"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_050310943.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050305374.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_050299869.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050308915.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex"
XP_050303592.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050304021.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050315687.1	6	Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3	"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism"
XP_050308920.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_050297132.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050298118.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_050307277.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_050293074.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050309119.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050308662.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050300684.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050305350.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050302681.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-77289	"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050297452.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050313085.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050302961.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050302031.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050295555.1	21	MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7220;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-6545	"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050296566.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050308751.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050314803.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050302635.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050308157.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050296752.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050307275.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050300779.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050308676.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_050309613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294372.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050295788.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050313537.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300451.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050313034.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Galactose metabolism"
XP_050307950.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050301702.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050297061.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050315547.1	1	Reactome: R-HSA-1614603	"Cysteine formation from homocysteine"
XP_050305881.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311796.1	4	Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132	"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_050308114.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050292768.1	2	KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112	"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_050296091.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295904.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050298933.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050305456.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050295482.1	7	KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-5362517	"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid"
XP_050295746.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055	"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_050296516.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050312712.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_050308553.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_050308497.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310805.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_050292700.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050297494.1	5	MetaCyc: PWY-6168;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism"
XP_050301692.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050313610.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050297241.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_050297221.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050310229.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_050293420.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7717;MetaCyc: PWY-6309	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050304776.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050299568.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050304696.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050314867.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050303279.1	19	Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-5625970	"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"Rho GTPase cycle";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"Myogenesis";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1"
XP_050296470.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050310944.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050296226.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050293155.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050298300.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_050301612.1	13	KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7184	"Pyrimidine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_050314250.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050296137.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303813.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050300595.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050307446.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050306808.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050304402.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050297499.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050299750.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_050297684.1	13	MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;Reactome: R-HSA-196836;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18	"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes"
XP_050295119.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050309552.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293330.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-983168	"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050293733.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050308630.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050305978.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050299029.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050309603.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050314874.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050295374.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_050304348.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050304809.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050305094.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_050307959.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050316126.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050298371.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation"
XP_050296723.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050300057.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050298401.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050303574.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050298549.1	5	KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922	"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050303198.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050297112.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050299754.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050296305.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050308423.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050305763.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050300711.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050294843.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050293227.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050310882.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050293501.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050310574.1	7	KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-6610;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-7805	"Purine metabolism";"Glyphosate degradation III";"Adenine salvage";"Purine salvage";"Neutrophil degranulation";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation"
XP_050297276.1	5	Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415	"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling"
XP_050293317.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050311771.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050293133.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050293589.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050297707.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050306462.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050315674.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050296560.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-432722	"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis"
XP_050305272.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050307371.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305397.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050315361.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050298654.1	3	KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246	"Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I"
XP_050306814.1	14	Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050301715.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050300797.1	12	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway"
XP_050301400.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050311886.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050312193.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050302399.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050311993.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312412.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050298229.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050293512.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296272.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050304009.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9646399	"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Aggrephagy"
XP_050307550.1	8	MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050309233.1	14	MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667	"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I"
XP_050309657.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050314875.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_050308688.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050309587.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050297497.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_050309549.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050313844.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050309386.1	15	Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050299366.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050297179.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_050310929.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050312456.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_050307654.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050312285.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050298405.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050305774.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050305155.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050309696.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290	"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_050309337.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050312400.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050301145.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050307787.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050316083.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_050295438.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050293637.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050305846.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050301139.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050307294.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296911.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050293389.1	27	Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453	"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response"
XP_050297526.1	24	Reactome: R-HSA-432040;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418597	"Vasopressin regulates renal water homeostasis via Aquaporins";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Ca2+ pathway";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (z) signalling events"
XP_050303392.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050299328.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050296484.1	1	MetaCyc: PWY-6771	"Rhamnogalacturonan type I degradation II (bacteria)"
XP_050298247.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050307769.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050312153.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050295166.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050293699.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050303966.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050314878.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050316291.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050314434.1	12	Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-75893	"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"TNF signaling"
XP_050314343.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050315744.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_050303521.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050315179.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050314439.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_050306708.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050295624.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302609.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297545.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304290.1	5	KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes"
XP_050301371.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050293228.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050302365.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050308452.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_050303017.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050298831.1	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050308850.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050316332.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050300671.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050301475.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24	"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050308446.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050314576.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050303444.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050316329.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050310069.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_050299719.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050315892.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050311153.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050306617.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_050314081.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050310402.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297568.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311548.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050309005.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050311043.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050314673.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050299230.1	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
XP_050297362.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050314293.1	5	Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_050296959.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050309225.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050310881.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725	"Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation"
XP_050311495.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050296125.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297110.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_050311558.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296149.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050309535.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801	"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD"
XP_050293315.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050304105.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050297042.1	18	KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA"
XP_050309959.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050294785.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050308974.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_050309741.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050304005.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050293163.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050295849.1	12	MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_050316235.1	7	KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11	"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_050310540.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050294719.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050304778.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050311496.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050294884.1	4	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenocysteine synthesis"
XP_050311901.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050304715.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050314020.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050304381.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_050302751.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050309782.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_050309165.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050296852.1	8	Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation"
XP_050312025.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050305955.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050316042.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_050310804.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_050310572.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619	"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis"
XP_050293117.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-381042	"IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"PERK regulates gene expression"
XP_050304415.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050295852.1	17	Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-4086398;Reactome: R-HSA-202424	"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"Ca2+ pathway";"Downstream TCR signaling"
XP_050304432.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050299712.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050315886.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050314414.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI"
XP_050307383.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism"
XP_050315060.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050299980.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050313574.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_050300115.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050315510.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050300233.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050302250.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050314006.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050309625.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050298607.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050300955.1	4	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Selenocompound metabolism"
XP_050300814.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
XP_050309236.1	14	Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055	"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis"
XP_050300897.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050297577.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304839.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050301166.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050302125.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_050297704.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050298128.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050310721.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050313508.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050307048.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1169408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism"
XP_050294013.1	10	KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11	"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism"
XP_050315750.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050308719.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050304028.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050305096.1	3	Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007	"Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy"
XP_050298372.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700	"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050295310.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_050296555.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050309346.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050299644.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050313780.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_050310095.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050309484.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_050312306.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050313578.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050305920.1	26	Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050316359.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050295020.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050299737.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050299123.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050311377.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050299846.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050304556.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050304029.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050301962.1	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
XP_050311097.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4	"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism"
XP_050296537.1	7	MetaCyc: PWY-7158;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-8964208	"L-phenylalanine degradation V";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism"
XP_050310423.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050306535.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions"
XP_050299329.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_050312506.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050305097.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_050314031.1	10	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-444257;Reactome: R-HSA-442742;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"RSK activation";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Thermogenesis"
XP_050314495.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050306077.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050299124.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050303066.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050308527.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050308154.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050302208.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050311167.1	14	KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302	"Citrate cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)"
XP_050297851.1	8	MetaCyc: PWY-6372;MetaCyc: PWY-6664;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6580;Reactome: R-HSA-1855183	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050311777.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050310170.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050305982.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050312191.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050303663.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050301427.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050312411.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050297446.1	7	Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050313741.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050315968.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050294434.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050306786.1	21	MetaCyc: PWY-7220;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7197;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Thiamine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050311911.1	6	MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978	"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism";"Defective GALT can cause Galactosemia"
XP_050305865.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050301219.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_050310333.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050292732.1	4	KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841	"Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)"
XP_050309784.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050300888.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050314822.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050310886.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050311557.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_050299932.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050294318.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050310346.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050296811.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_050313069.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050300899.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_050300447.1	9	KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway"
XP_050309738.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050299030.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_050314872.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050306552.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050298280.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050302184.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050304800.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_050310556.1	11	KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791	"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III"
XP_050308148.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050316040.1	10	MetaCyc: PWY-5839;MetaCyc: PWY-5844;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-5891;MetaCyc: PWY-5890;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892	"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis"
XP_050303034.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050298140.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112	"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050307193.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050293232.1	11	MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053	"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II"
XP_050308258.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050293421.1	6	MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_050293789.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305732.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050304291.1	5	KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556	"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism";"ROS and RNS production in phagocytes"
XP_050301353.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_050315046.1	10	MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890;MetaCyc: PWY-5849;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5839;MetaCyc: PWY-5844	"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis"
XP_050295577.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050303467.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050311907.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_050300548.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050299162.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050293073.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_050312006.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313998.1	8	KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_050301049.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_050305143.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050312854.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050311408.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307571.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050313738.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050307693.1	7	Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553	"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs"
XP_050296862.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050294865.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297992.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050309383.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050295856.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050313282.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050298711.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050314827.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050292773.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050313430.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050296610.1	10	MetaCyc: PWY-7571;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-922	"Ferrichrome A biosynthesis";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I"
XP_050316177.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050303278.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050297017.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050309600.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050306406.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050305102.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050300936.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_050307046.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-1169408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"ISG15 antiviral mechanism"
XP_050302604.1	8	KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism"
XP_050313534.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297698.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050306909.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050311172.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050314444.1	6	MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism"
XP_050304239.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050299163.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050313679.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050316327.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050306714.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296148.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050314814.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8964038	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Recycling pathway of L1";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"LDL clearance"
XP_050306739.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050313242.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050292809.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050297187.1	22	MetaCyc: PWY-7053;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7724	"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_050294996.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050295030.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050316265.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050303653.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050311994.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298913.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050294655.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-450341;Reactome: R-HSA-8862803;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-2871796;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472	"MAPK6/MAPK4 signaling";"Activation of the AP-1 family of transcription factors";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"FCERI mediated MAPK activation";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050293510.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050300397.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050311381.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050303350.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313112.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050314897.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050298598.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050301220.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050314711.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050311559.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050303171.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050314392.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050307056.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050293419.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-6309	"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_050307410.1	7	KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-4984;MetaCyc: PWY-46;MetaCyc: PWY-31	"Arginine biosynthesis";"Urea cycle";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Canavanine degradation"
XP_050301591.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050313293.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050299736.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050303606.1	27	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73856;Reactome: R-HSA-167242;Reactome: R-HSA-159230;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-77595;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6807505;Reactome: R-HSA-159231;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6803529	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Processing of Intronless Pre-mRNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA Derived from an Intronless Transcript";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing"
XP_050309620.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis"
XP_050312134.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050302423.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050302397.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050296413.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_050303982.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050306488.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050314877.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050300151.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050297038.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_050316366.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050293884.1	7	KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23	"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism"
XP_050306237.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050298601.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050312018.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050303195.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_050308198.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050297768.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_050296891.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
XP_050307656.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050300878.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050296173.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050297596.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050314994.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050297107.1	5	Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383	"Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050304637.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050310076.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050296094.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050309532.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050312103.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050300667.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050296913.1	5	KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Sphingolipid metabolism";"Galactose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050312206.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050297766.1	13	MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-156590	"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione conjugation"
XP_050312696.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050303257.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050310549.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050293000.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5467337	"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"RAF activation";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding"
XP_050310646.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050305650.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050314187.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050308159.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050307026.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050306807.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050313788.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296198.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy"
XP_050308100.1	17	Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050312080.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-6703	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis"
XP_050310355.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II"
XP_050304112.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation"
XP_050303729.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_050301223.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050311996.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301515.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis"
XP_050307450.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050296136.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305159.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_050296429.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050311398.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050301024.1	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate"
XP_050296559.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828	"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis"
XP_050294373.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050312366.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050304594.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_050298808.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050295280.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050304954.1	5	Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695	"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation"
XP_050296089.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302705.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_050299933.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050299599.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050305363.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050316339.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_050311369.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050315746.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050304868.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050314485.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050294148.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050293245.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050315011.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050297873.1	9	MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94	"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism"
XP_050294476.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_050302805.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050303262.1	8	KEGG: 00330+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41	"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis"
XP_050299088.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050301016.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333	"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050313110.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050306992.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050305778.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050310079.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050301433.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580	"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence"
XP_050313507.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol"
XP_050314077.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-3899300;Reactome: R-HSA-9609690	"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors";"HCMV Early Events"
XP_050310228.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050299718.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050295274.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050306857.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050306861.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050312705.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050312131.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050308046.1	5	KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892	"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)"
XP_050299996.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_050296567.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050299643.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-75105	"Nuclear Receptor transcription pathway";"Fatty acyl-CoA biosynthesis"
XP_050304955.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050302655.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638	"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins"
XP_050306865.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050295546.1	13	Reactome: R-HSA-416993;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-182218	"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation"
XP_050304796.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050304968.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050298409.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050297099.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-111932	"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB"
XP_050315626.1	20	MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538;Reactome: R-HSA-6798695	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Neutrophil degranulation"
XP_050316028.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51	"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_050293047.1	16	Reactome: R-HSA-70171;MetaCyc: PWY-5484;Reactome: R-HSA-70263;KEGG: 00010+4.2.1.11;MetaCyc: PWY-2221;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-8004	"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I"
XP_050307657.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050314796.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_050300271.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050293981.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050304961.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050296165.1	3	Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2	"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway"
XP_050308382.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050300354.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_050314268.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050292849.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050304967.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050299098.1	15	Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084	"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_050315582.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_050316167.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050311872.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050309219.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050293803.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050308602.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300351.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050294759.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050303652.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050314366.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050296607.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_050311555.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050301523.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression"
XP_050315549.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism"
XP_050313198.1	7	Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_050309465.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050304299.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050304774.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050310387.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_050308288.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_050311155.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050293452.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050298133.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050301110.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050311604.1	4	Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050296659.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050300047.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050313480.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-432142	"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron assembly";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"VLDL clearance";"LDL remodeling";"LDL clearance";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Platelet sensitization by LDL"
XP_050302881.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050301406.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation"
XP_050312520.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050298947.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050308379.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296964.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050312038.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050306661.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050304172.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050293037.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050310395.1	6	Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_050314904.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050303151.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813	"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Aggrephagy";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids"
XP_050312332.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050315470.1	3	Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050296124.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050292770.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050294937.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050301952.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050301142.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050307066.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050302754.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_050301163.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050293010.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_050308976.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050296751.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050311370.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050298219.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050307362.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050309477.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_050308285.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_050303568.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050297874.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis"
XP_050304067.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050295743.1	10	MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055	"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis"
XP_050301684.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_050307111.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050316410.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050301401.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050312856.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050315760.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050293779.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050302658.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050302183.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050314685.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050297232.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_050301918.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050307958.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050314011.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050297866.1	5	Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684	"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state"
XP_050304819.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050314795.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-418594	"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events"
XP_050305321.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050293314.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050295281.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050310723.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050308294.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050311680.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050307078.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050306349.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_050297628.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050303083.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050303100.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050309452.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050301355.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_050312403.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050314794.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_050311981.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303871.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050305769.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050301676.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306466.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-5689880;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes"
XP_050308627.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_050298860.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050298949.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168	"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311960.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295172.1	3	Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_050308195.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050295455.1	8	Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4	"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine metabolism"
XP_050308874.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050313532.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311710.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050313646.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)"
XP_050308047.1	29	Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862	"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HSF1 activation";"Translesion synthesis by POLK"
XP_050299396.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_050300905.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050293631.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050299778.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050302335.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050297453.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050293137.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_050298020.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050315463.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050314475.1	16	Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-512988;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-114604	"Costimulation by the CD28 family";"Rho GTPase cycle";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-7 signaling";"RET signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade"
XP_050311128.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050308376.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050302440.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050304073.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050315830.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050308193.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302526.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050315909.1	11	Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-111458	"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome"
XP_050313559.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050316385.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4641258	"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Degradation of DVL"
XP_050308383.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050309335.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050302816.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050308442.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_050316130.1	6	Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803211	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_050313150.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050309120.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050310251.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050293576.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050298048.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050303095.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050307052.1	12	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72662	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_050307962.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050292719.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050307529.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050313933.1	17	KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599	"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency"
XP_050302921.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050310006.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050315120.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050298176.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050313693.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050310603.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050314644.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050299581.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050294991.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050304134.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_050299608.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_050296863.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050309766.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050312177.1	6	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_050296080.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050313142.1	11	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050306522.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050312817.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation"
XP_050312427.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
XP_050311792.1	6	Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism"
XP_050310566.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050308477.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050300922.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050315923.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472	"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050295251.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050297004.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_050304633.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050299519.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050314057.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050309586.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050312182.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050316396.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050304395.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050313931.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050299398.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050312483.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050307653.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050305788.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050301105.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050309214.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050295349.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050310048.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050316307.1	4	Reactome: R-HSA-6782861;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_050311974.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050315821.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050296132.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302325.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050315672.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050303537.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050314876.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_050296713.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050303544.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050302794.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050303823.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050301521.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_050309644.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050300903.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050301902.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050293147.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050313847.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050299225.1	10	KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway"
XP_050313792.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050300813.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615	"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation"
XP_050306489.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050294237.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050292776.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050308098.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050303387.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050312359.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050307023.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050299268.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050312414.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050293240.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-168333	"RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050296326.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_050315493.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050304407.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050305935.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050312109.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050302403.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050313205.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050305905.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050296126.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300297.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050309780.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050315000.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294135.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis"
XP_050313240.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050308097.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050308003.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050316120.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_050296924.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050296870.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050294149.1	52	Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424	"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling"
XP_050313318.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050298902.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050297991.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050293205.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050315103.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050307900.1	19	Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Translation initiation complex formation";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_050293278.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_050310233.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050309370.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050304042.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_050298434.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050303738.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_050313416.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050300988.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050295742.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_050314801.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050309375.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69205	"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription"
XP_050311890.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050296623.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050304451.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949	"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin"
XP_050309185.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_050312493.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050314376.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_050303824.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050316328.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050300930.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050292783.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050295297.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050311134.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050293973.1	6	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_050303750.1	6	KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221	"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)"
XP_050297015.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050313778.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_050313151.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050303905.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050294872.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050304757.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050303359.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050302424.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050315473.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050302542.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_050310984.1	42	MetaCyc: PWY-5138;KEGG: 00903+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-1361;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-7007;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7401;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7779;KEGG: 00280+4.2.1.17+1.1.1.35	"Fatty acid beta-oxidation IV (unsaturated, even number)";"Limonene and pinene degradation";"Geraniol degradation";"Fermentation to 2-methylbutanoate";"Androstenedione degradation";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoyl-coa degradation I (aerobic)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation";"Toluene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Benzoate degradation";"Tryptophan metabolism";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Fatty acid degradation";"Aminobenzoate degradation";"Fatty acid salvage";"Butanoate metabolism";"Glutaryl-coa degradation";"Methyl tert-butyl ether degradation";"Valine, leucine and isoleucine degradation"
XP_050311525.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_050311992.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313440.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050307936.1	29	Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-6804760;Reactome: R-HSA-5693571;Reactome: R-HSA-69541;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Human papillomavirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Methylation";"Nonhomologous End-Joining (NHEJ)";"Stabilization of p53";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway"
XP_050316335.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050304739.1	3	Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508	"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_050293984.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050310247.1	3	MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403	"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_050303861.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050308766.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation"
XP_050299066.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_050311074.1	5	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_050306375.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_050314461.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050296290.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-948021;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER"
XP_050308140.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_050314476.1	16	Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-389357	"RET signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Rho GTPase cycle";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"CD28 dependent PI3K/Akt signaling"
XP_050313202.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050309464.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050293253.1	5	KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage"
XP_050295963.1	13	MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-5122	"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis"
XP_050315587.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050298403.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050307712.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050294875.1	9	MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism"
XP_050303351.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050296100.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298725.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_050307999.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050300990.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050314024.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050311157.1	25	Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-381771;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657	"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors"
XP_050294487.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050306046.1	5	Reactome: R-HSA-168315;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"Inhibition of Host mRNA Processing and RNA Silencing";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050302614.1	12	Reactome: R-HSA-196780;KEGG: 00280+6.4.1.3;MetaCyc: PWY-5789;Reactome: R-HSA-71032;Reactome: R-HSA-3371599;MetaCyc: PWYG-321;KEGG: 00630+6.4.1.3;MetaCyc: PWY-6728;KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5743	"Biotin transport and metabolism";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propionyl-CoA catabolism";"Defective HLCS causes multiple carboxylase deficiency";"";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"3-hydroxypropanoate cycle"
XP_050312445.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_050312254.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050308532.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885	"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins"
XP_050300593.1	18	MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7176	"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis"
XP_050293717.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_050308720.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108	"RORA activates gene expression";"RMTs methylate histone arginines";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050297451.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050313968.1	11	KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"p38MAPK events";"VEGFA-VEGFR2 Pathway";"Thermogenesis"
XP_050300810.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_050299909.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle"
XP_050293276.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050302006.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050315069.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050297981.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050313356.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050300180.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050311798.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_050304547.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_050298333.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050306713.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050312344.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050312392.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050310738.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050309701.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050301276.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050309551.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport"
XP_050311112.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050309826.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050298874.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases"
XP_050307898.1	18	MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-5392	"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II"
XP_050301790.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310562.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050303588.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_050296967.1	6	MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation"
XP_050309107.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294494.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050313845.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation"
XP_050294882.1	3	Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803	"tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II"
XP_050299731.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050293264.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050309396.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050296803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307795.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050294863.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050314108.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050294853.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs"
XP_050306991.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050295457.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050313148.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050313623.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050314314.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050299926.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050307553.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050310240.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050314893.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050307800.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050300361.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050311453.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050296452.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050310335.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050311774.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050301238.1	8	KEGG: 00051+4.2.1.47;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-5740	"Fructose and mannose metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis"
XP_050309176.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050302239.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_050314907.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_050304805.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050294240.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_050294824.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050303355.1	9	KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52	"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis"
XP_050294383.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_050294822.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050301683.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis"
XP_050313841.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050297691.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050308218.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050303376.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297008.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis"
XP_050311048.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050293611.1	1	MetaCyc: PWY-6771	"Rhamnogalacturonan type I degradation II (bacteria)"
XP_050295826.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050299567.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050303985.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-5674400	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050309006.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050303030.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050309700.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050298326.1	10	MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-6366;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;MetaCyc: PWY-6365	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis"
XP_050309513.1	7	Reactome: R-HSA-174403;MetaCyc: PWY-6840;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2	"Glutathione synthesis and recycling";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism"
XP_050315847.1	3	Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267	"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050308137.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481	"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints"
XP_050298143.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_050297363.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050301954.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050310609.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050295735.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050312200.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050298509.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050299588.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050295617.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050311523.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition"
XP_050296551.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050297626.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050311135.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050302233.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050297629.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050305166.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050308160.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050293138.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_050313627.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050299852.1	13	MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050309949.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050305396.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050308735.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050302674.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050298802.1	10	KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-6613	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Folate transformations I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_050295282.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_050308644.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050304141.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050315185.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050297695.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050314423.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism"
XP_050311490.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050300415.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_050297011.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II"
XP_050304807.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050312832.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051	"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I"
XP_050313801.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050314294.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050304166.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298868.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050301799.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050305641.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304000.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050310265.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050306897.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050309121.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050293066.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-983189	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Kinesins"
XP_050313263.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050293583.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-4755583;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Synthesis of Dolichyl-phosphate"
XP_050309485.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_050307086.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050293629.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050315826.1	4	MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050294454.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050308926.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_050295641.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050310679.1	3	Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis"
XP_050310978.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_050300038.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050292848.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050295619.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050312860.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050314648.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050308702.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050293461.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050307098.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-561	"Oxidative phosphorylation";"Methylaspartate cycle";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050300616.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050297637.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050307826.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_050294228.1	8	Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Superpathway of glucose and xylose degradation"
XP_050306978.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050310784.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050298276.1	7	KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;Reactome: R-HSA-71336	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_050299178.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050308879.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050314873.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_050311824.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050309190.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050311498.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050307621.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050304050.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050314712.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050293307.1	15	Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383	"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050311391.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050308781.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050306166.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_050300762.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-6790901	"Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol"
XP_050306505.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050315181.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050298535.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050313932.1	17	MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381	"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_050305976.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050309651.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050316318.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Formation of apoptosome"
XP_050298172.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050309720.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050311956.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312179.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_050297791.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050300567.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_050300401.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_050310045.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_050305749.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050300709.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050305762.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_050301225.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050307740.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_050294499.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_050313379.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294440.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050294714.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050292996.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050313470.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050305256.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050299164.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050296771.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_050298329.1	5	MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050303273.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050297708.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050297576.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308112.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050301809.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174178	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050304890.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050314042.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_050298863.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050303263.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-5625970;Reactome: R-HSA-114604	"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate PAKs";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade"
XP_050304977.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050300453.1	9	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050306740.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050313940.1	7	MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Purine metabolism";"Drug metabolism - other enzymes"
XP_050312398.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050297619.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050308612.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050297177.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050313133.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050314936.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355	"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction"
XP_050299372.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050305384.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050310065.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050295131.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050307884.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050296448.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050314647.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050300149.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050313355.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050314586.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050316409.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050302086.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_050301990.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311617.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050313289.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050299862.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_050297181.1	6	KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_050312361.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050296248.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050313237.1	4	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050301457.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050304829.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662	"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism"
XP_050295444.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050311409.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050304059.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050310945.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050300491.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114516;Reactome: R-HSA-5099900	"Trafficking of GluR2-containing AMPA receptors";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4"
XP_050304818.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050311987.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302128.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314921.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050313674.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050293870.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050301602.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050296822.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-162594	"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_050314054.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050306738.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050314017.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050307920.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones"
XP_050298867.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050308674.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050302671.1	6	Reactome: R-HSA-9610379;Reactome: R-HSA-983168;Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"HCMV Late Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_050308413.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050310734.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050294253.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_050302695.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050293115.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050305984.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311982.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304487.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050303252.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050294517.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050308870.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050303284.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050310332.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050295831.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050314035.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050311973.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303881.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_050311296.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050308346.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_050294455.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050309919.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050316285.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050314360.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_050295537.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_050295949.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050301690.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050306868.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_050304196.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_050314041.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_050307223.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050303281.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_050296208.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050304966.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050314732.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050304665.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050315073.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050292992.1	12	Reactome: R-HSA-399719;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8	"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism"
XP_050308119.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050294919.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050297076.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244	"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation"
XP_050292956.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050303454.1	2	Reactome: R-HSA-111458;Reactome: R-HSA-9627069	"Formation of apoptosome";"Regulation of the apoptosome activity"
XP_050303383.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_050298923.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050299717.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050299450.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Formation of the beta-catenin:TCF transactivating complex";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_050306651.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_050300849.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050316304.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050308178.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX"
XP_050296532.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050299897.1	12	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050301733.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_050306157.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050302554.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050300150.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050302391.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050310598.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;MetaCyc: PWY-7511	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination"
XP_050309141.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050309902.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050312002.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312396.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050305523.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_050293058.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050299995.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_050297557.1	16	Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_050310756.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050307530.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050312161.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050306875.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition"
XP_050306696.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_050311330.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050308541.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333	"HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050315575.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_050311980.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297357.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050294514.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050298171.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050296394.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050296244.1	9	Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507	"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation"
XP_050299800.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050296768.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050301140.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050314626.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050316383.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050300448.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050298753.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050297553.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310256.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050302494.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050314706.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050308753.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050296142.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050305727.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_050316172.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism"
XP_050316322.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050314103.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050296578.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050307036.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050305462.1	10	MetaCyc: PWY-7921;Reactome: R-HSA-162699;MetaCyc: PWY-7661;MetaCyc: PWY-7922;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377	"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)"
XP_050292974.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050309534.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050303019.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-5627123	"Clathrin-mediated endocytosis";"RHO GTPases activate PAKs"
XP_050308524.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050294874.1	9	KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115	"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_050308191.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9617629	"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation"
XP_050293956.1	16	Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050304436.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050294547.1	17	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Thermogenesis"
XP_050311876.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050298454.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050293151.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050311724.1	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050302253.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050292855.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050301384.1	24	KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-202424;Reactome: R-HSA-5607764	"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"mTOR signaling pathway";"VEGFR2 mediated cell proliferation";"RSK activation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"RHO GTPases activate PKNs";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Integrin signaling";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling"
XP_050306374.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050292883.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885	"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins"
XP_050297250.1	3	KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism"
XP_050303360.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050311772.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050294071.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050309113.1	5	MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_050296953.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050314800.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050295303.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050304110.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497	"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050316266.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050314848.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050309800.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050299405.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050304241.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_050308190.1	26	Reactome: R-HSA-201722;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-210744	"Formation of the beta-catenin:TCF transactivating complex";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_050302409.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050312442.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306360.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050303271.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-983231	"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate PAKs";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"RHO GTPases activate IQGAPs";"EGFR downregulation";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"Myogenesis";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production"
XP_050302173.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050312930.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306706.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050305231.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050294876.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050313071.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050311206.1	2	Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Gluconeogenesis";"Glycolysis"
XP_050313696.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050293320.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050303640.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050302469.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050312521.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_050294216.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050304171.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050293980.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050307049.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-1169408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism"
XP_050296544.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050303586.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050310854.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050299320.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050299741.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050313239.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050296602.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_050302261.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050312505.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050304200.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_050311411.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050312452.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050304259.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_050310064.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050295162.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050313488.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050303929.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050303228.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050307794.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_050314196.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050315928.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69205	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription"
XP_050314028.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050299732.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050297569.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300141.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050313363.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050313283.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050293990.1	9	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_050297003.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158;MetaCyc: PWY-8099	"Folate biosynthesis";"L-phenylalanine degradation V";"Tetrahydropteridine recycling"
XP_050312532.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050305815.1	4	KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558	"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine"
XP_050307107.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050304548.1	2	KEGG: 00710+2.7.1.14;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_050301358.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050312462.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050304370.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050314584.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050298901.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050306891.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050307077.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050297197.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050310877.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050313805.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050310555.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050306905.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5538	"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI"
XP_050297669.1	8	Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-373080;Reactome: R-HSA-5340588;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-4641263	"Asymmetric localization of PCP proteins";"Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"RNF mutants show enhanced WNT signaling and proliferation";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Regulation of FZD by ubiquitination"
XP_050293506.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050301441.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2"
XP_050309285.1	5	KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7204	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_050298178.1	57	Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837	"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation"
XP_050310611.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050306377.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_050305153.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050314943.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-114608	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Platelet degranulation"
XP_050300796.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050307327.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148	"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050295346.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050308646.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050307273.1	8	MetaCyc: PWY-7921;Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633	"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_050311298.1	1	MetaCyc: PWY-6771	"Rhamnogalacturonan type I degradation II (bacteria)"
XP_050296950.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050307968.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050311900.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050307092.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_050310879.1	3	Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60	"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation"
XP_050294031.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_050301752.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050297593.1	33	Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159227	"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA"
XP_050303353.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_050311422.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050313620.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_050310308.1	6	MetaCyc: PWY-7790;MetaCyc: PWY-5686;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10	"UMP biosynthesis II";"UMP biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism"
XP_050294157.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050316292.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050308579.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050294073.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050307030.1	4	KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050298386.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050308079.1	3	Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050307708.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050302571.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944	"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2"
XP_050303983.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050314058.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050298123.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-9018519	"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"Estrogen-dependent gene expression"
XP_050309483.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_050305726.1	4	Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-6783310;Reactome: R-HSA-4419969	"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Fanconi Anemia Pathway";"Depolymerisation of the Nuclear Lamina"
XP_050295648.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050301026.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway"
XP_050312852.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050314658.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050293503.1	10	Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-168138;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-109704	"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Toll Like Receptor 9 (TLR9) Cascade";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Phosphatidylinositol signaling system";"PI3K Cascade"
XP_050311019.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_050302206.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-4086400;Reactome: R-HSA-373080	"Asymmetric localization of PCP proteins";"PCP/CE pathway";"Class B/2 (Secretin family receptors)"
XP_050307960.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050309173.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050293187.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050305768.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050305119.1	19	MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00620+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;Reactome: R-HSA-70263	"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis"
XP_050315757.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050312975.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050311127.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050316390.1	13	KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050315008.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_050300400.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050298976.1	18	Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4	"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism"
XP_050299677.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050308666.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050314014.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050306373.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_050302720.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050313206.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050313344.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050294022.1	10	KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11	"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism"
XP_050316360.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050299557.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579	"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange"
XP_050314559.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050297136.1	7	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050304380.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_050310098.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050293362.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050303593.1	18	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72706	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050302101.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050300443.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050294456.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050315076.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050296812.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050313934.1	19	Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275	"Regulation of TLR by endogenous ligand";"VLDL clearance";"LDL remodeling";"Scavenging by Class B Receptors";"LDL clearance";"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron assembly";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation"
XP_050298748.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050314034.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050315302.1	6	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980	"Cristae formation";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis"
XP_050299734.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050302703.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050311147.1	8	MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_050292748.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296088.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301463.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_050298572.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050315636.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050304012.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion"
XP_050312181.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050295190.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050296451.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050308006.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050305364.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050311582.1	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050306376.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_050299725.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050308765.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_050306101.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050309343.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050305850.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_050306610.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050302030.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050309920.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050315831.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050293755.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050292985.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-442982	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050316213.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_050303906.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050312303.1	4	Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050306765.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050307303.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050311995.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305748.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050310883.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050296611.1	5	KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22	"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_050304592.1	6	KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;MetaCyc: PWY-6363	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_050314295.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050311379.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050315150.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_050306815.1	14	Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_050296389.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050310424.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050315841.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050302404.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050315829.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050306030.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis"
XP_050300022.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_050306900.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050301651.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050308701.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311216.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_050293467.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050294032.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_050301626.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050315146.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050297439.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_050310375.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276	"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_050295163.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_050313558.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_050303499.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation"
XP_050296748.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050313719.1	5	KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661	"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050312857.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050309030.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050301104.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050303240.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050299437.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050293713.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050310671.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_050306506.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050308145.1	3	KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050298138.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050300248.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_050310875.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_050294935.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050305830.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050297178.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050308224.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_050293457.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050305386.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050311962.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310111.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050296947.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050295761.1	8	Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_050300940.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation"
XP_050292755.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050309827.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050303923.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050308640.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050297688.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_050300919.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050313695.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050315125.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_050298666.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050293319.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050306184.1	4	KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_050306371.1	6	KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004	"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I"
XP_050299720.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050299129.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050308344.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_050305236.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050308660.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050304793.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050297574.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303404.1	4	Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781	"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis"
XP_050314452.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827	"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex"
XP_050302453.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway"
XP_050309598.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050305874.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050301015.1	4	Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Laminin interactions";"MET activates PTK2 signaling"
XP_050296380.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050301596.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_050306766.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050312747.1	3	Reactome: R-HSA-1237112;KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361	"Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050294951.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_050302007.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_050307706.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314649.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050309830.1	11	MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_050293873.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050300776.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_050310261.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050313241.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_050311961.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304891.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_050293451.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050316319.1	4	KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis"
XP_050308675.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050295545.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050311857.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050304815.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_050295737.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic"
XP_050293596.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050292977.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050305372.1	12	MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872	"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_050294080.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050314772.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050293937.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-5173105;Reactome: R-HSA-2022854	"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation";"Keratan sulfate biosynthesis"
XP_050302534.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050305644.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050312384.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050308783.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050305151.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050304041.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_050311808.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050315362.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_050306480.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050305081.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_050315483.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050312826.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_050296594.1	22	MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7726;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-7053;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7725;MetaCyc: PWY-7601	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050303029.1	8	KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Galactose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050315627.1	20	KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-6728;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_050294478.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050308911.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050307610.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050302050.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050316180.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050294030.1	10	Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861	"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_050296134.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295321.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050305103.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050311787.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050316260.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050301539.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112	"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification"
XP_050294146.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050298928.1	5	Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001	"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation";"Sialic acid metabolism"
XP_050306515.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050295538.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1"
XP_050294847.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050298369.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944	"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2"
XP_050298021.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050294312.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050315056.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_050296021.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050300326.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050293852.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450	"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC"
XP_050304176.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050299601.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050302733.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050309213.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_050307742.1	11	Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050293593.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050300010.1	10	KEGG: 00710+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042	"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)"
XP_050294978.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050307272.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895	"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis"
XP_050303035.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050295786.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050305980.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050294057.1	5	MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3	"Folate transformations II (plants)";"Metabolism of folate and pterines";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"One carbon pool by folate"
XP_050304082.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050302792.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050310372.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_050311887.1	9	Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050306828.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050299596.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050306941.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050303265.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_050296049.1	5	MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_050303381.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_050306382.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050296581.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050306034.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050310758.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050309912.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_050307853.1	8	MetaCyc: PWY-5723;Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6	"Rubisco shunt";"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050305925.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050311091.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050293652.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050309626.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050294794.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_050302322.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_050311682.1	9	MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle"
XP_050310171.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050299787.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050306263.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050301144.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050312721.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050315629.1	20	KEGG: 00020+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-6728;Reactome: R-HSA-163765;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5913;Reactome: R-HSA-6798695;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Methylaspartate cycle";"ChREBP activates metabolic gene expression";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Neutrophil degranulation";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_050298370.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-9022692	"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity"
XP_050302064.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050306262.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314086.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050308707.1	7	KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980	"Photosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis"
XP_050303714.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050308060.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050312256.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050309540.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050311965.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304102.1	3	KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_050316303.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_050308827.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050296307.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050306537.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction"
XP_050295988.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050301451.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050301065.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050307627.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050296254.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293401.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050312790.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050298111.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050301480.1	6	Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism"
XP_050299261.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050295625.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050305490.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_050293289.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_050311173.1	1	KEGG: 00565+3.1.1.47	"Ether lipid metabolism"
XP_050297507.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050314453.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050306663.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation"
XP_050309896.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange"
XP_050292694.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939236	"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050307797.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050295587.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050296107.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307474.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_050297067.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050304322.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_050315776.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050315971.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Nuclear signaling by ERBB4"
XP_050293203.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050299783.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050294713.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050302277.1	5	KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201	"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I"
XP_050307889.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050307112.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050304848.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050305415.1	3	Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45	"Glycosphingolipid metabolism";"Other glycan degradation";"Sphingolipid metabolism"
XP_050296139.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308650.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050309234.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Plasmalogen biosynthesis"
XP_050307458.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_050292920.1	9	Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER"
XP_050306481.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050306029.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359	"Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels"
XP_050293774.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_050311371.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050294708.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050292814.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050297559.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-113507	"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation"
XP_050294878.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050307228.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050294637.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298712.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050314511.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050314321.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050302610.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050293644.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_050305780.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050295017.1	6	Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690	"HDACs deacetylate histones";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events"
XP_050297709.1	9	KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule"
XP_050315770.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050294638.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050315206.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050295090.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050315959.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050315827.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050309739.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050302038.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050298909.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050296033.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_050305965.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050303519.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050315057.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050311521.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050298231.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050303169.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050294809.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050307574.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050314151.1	5	Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-376172	"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"DSCAM interactions"
XP_050305461.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307746.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050302081.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_050315187.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050313804.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050312152.1	5	Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408	"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism"
XP_050313886.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-9610379	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"HCMV Late Events"
XP_050301919.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050311493.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_050298918.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050311827.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050304653.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050292785.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050307626.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050312201.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050311349.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses"
XP_050299740.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050310633.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050299266.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050310909.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_050304559.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_050310612.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050313280.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_050296116.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294453.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050313114.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050308197.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050307005.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050307877.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050311536.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050300964.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_050309277.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050310552.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II"
XP_050308153.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050315565.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_050312102.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050308658.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050296946.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050299130.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050310780.1	3	KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3	"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism"
XP_050310334.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050308092.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050295731.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050296384.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050295307.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050306296.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402	"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex"
XP_050295576.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050301385.1	24	Reactome: R-HSA-5218921;Reactome: R-HSA-444257;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-5607764;Reactome: R-HSA-202424	"VEGFR2 mediated cell proliferation";"RSK activation";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"RHO GTPases activate PKNs";"Activation of AKT2";"Integrin signaling";"VEGFR2 mediated vascular permeability";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling"
XP_050300568.1	4	MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis"
XP_050306571.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050307074.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050296954.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050305873.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050300352.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050315669.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111463;Reactome: R-HSA-111464	"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Formation of apoptosome";"Regulation of the apoptosome activity";"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_050309894.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_050313364.1	5	KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling"
XP_050292919.1	9	Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER"
XP_050312495.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050311758.1	12	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-9648025;Reactome: R-HSA-400253;Reactome: R-HSA-68877;KEGG: 04658+3.1.3.16;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788	"T cell receptor signaling pathway";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"EML4 and NUDC in mitotic spindle formation";"Circadian Clock";"Mitotic Prometaphase";"Th1 and Th2 cell differentiation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling"
XP_050294482.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III"
XP_050297472.1	12	Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817	"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Stachyose degradation";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Glycogen synthesis";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050294738.1	7	KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67	"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_050297000.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276	"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_050298964.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050296899.1	8	MetaCyc: PWY-7734;MetaCyc: PWY-7765;MetaCyc: PWY-6309;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-5651;MetaCyc: PWY-7733;KEGG: 00380+3.5.1.9	"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Tryptophan metabolism"
XP_050296820.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050308158.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050304937.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis"
XP_050305682.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_050306655.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050305739.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050298375.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496	"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs"
XP_050310399.1	10	KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6536;Reactome: R-HSA-916853;MetaCyc: PWY-6535;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00640+2.6.1.19	"Butanoate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation III";"Degradation of GABA";"4-aminobutanoate degradation I";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV";"Propanoate metabolism"
XP_050302257.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050296263.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050309953.1	11	Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597	"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events"
XP_050299784.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050305385.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302963.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050304277.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050314248.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050304058.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050300815.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-5628897	"Macroautophagy";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes"
XP_050301988.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050309611.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050311158.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050293466.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050303067.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050303150.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050304549.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_050295309.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050302753.1	1	Reactome: R-HSA-427601	"Multifunctional anion exchangers"
XP_050313421.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050299451.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050316111.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)"
XP_050312296.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_050308901.1	4	Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258	"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_050314152.1	5	Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638	"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway"
XP_050313836.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation"
XP_050305502.1	8	Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16	"Synthesis of PG";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation"
XP_050298453.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050294477.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_050299505.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050309637.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050312413.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050294626.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050295790.1	4	Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394	"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER"
XP_050311095.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism"
XP_050315976.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050301634.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050316148.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257	"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN"
XP_050296096.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294512.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296367.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050306229.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459	"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050298302.1	18	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;KEGG: 00970+6.1.1.1;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-379726;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Aminoacyl-tRNA biosynthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Mitochondrial tRNA aminoacylation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050298895.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050309595.1	10	Reactome: R-HSA-163680;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209	"AMPK inhibits chREBP transcriptional activation activity";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Lipophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_050298124.1	11	Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression"
XP_050307212.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050306035.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050309530.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050302663.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050300251.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_050308207.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050299152.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050311367.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307308.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-8951664	"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport";"Neddylation"
XP_050308093.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050296579.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050299721.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050312390.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050294758.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050307478.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050303253.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_050297265.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895	"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis"
XP_050304923.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050307903.1	6	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050296949.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050311406.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310118.1	11	Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050301258.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050312508.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_050299898.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050308808.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050306601.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050310755.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_050307191.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050294950.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050316115.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050296767.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050296227.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050314039.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050312746.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050300000.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050314888.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050298278.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050315671.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050300291.1	3	Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6"
XP_050315012.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050296528.1	4	MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050294717.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050292837.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_050314578.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050307226.1	25	Reactome: R-HSA-8939902;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8939256;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8936459;Reactome: R-HSA-8941284;Reactome: R-HSA-8951936;Reactome: R-HSA-8939242;Reactome: R-HSA-8941326;Reactome: R-HSA-8941858;Reactome: R-HSA-8939243;Reactome: R-HSA-8877330;Reactome: R-HSA-8940973;Reactome: R-HSA-8934593;Reactome: R-HSA-8878166;Reactome: R-HSA-8949275;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8951911;Reactome: R-HSA-8939246;Reactome: R-HSA-8941332	"Regulation of RUNX2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates chondrocyte maturation";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates bone development";"Regulation of RUNX3 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation by RUNX2";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration"
XP_050309089.1	18	MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925	"Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PG"
XP_050315042.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050294325.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050316121.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050314935.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_050296390.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050315214.1	13	Reactome: R-HSA-3371511;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-8866654;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-5689877	"HSF1 activation";"Aggrephagy";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Josephin domain DUBs"
XP_050308072.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050297657.1	4	Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72	"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis"
XP_050300211.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_050300369.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-166208	"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling"
XP_050306307.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050310119.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050303485.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_050300801.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Rho GTPase cycle";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway"
XP_050304753.1	3	Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis"
XP_050314595.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050306845.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631	"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility"
XP_050310210.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050308872.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050303020.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_050312507.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050305017.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-983231;Reactome: R-HSA-8939236	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050309528.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050305934.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050293393.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050302487.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050313319.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_050304444.1	10	Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends"
XP_050297580.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050300824.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050306504.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050299952.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050303894.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050304252.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_050314440.1	4	MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism"
XP_050299305.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050300717.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050293008.1	8	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_050295809.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050301260.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050310272.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050297108.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-163615	"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation"
XP_050295447.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050302414.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050311957.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050293578.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050307069.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050309578.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050293688.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050308656.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050293895.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050304319.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601	"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_050293646.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050303872.1	3	KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246	"Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I"
XP_050314204.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050302513.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050305673.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_050293011.1	4	Reactome: R-HSA-2672351;MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Stimuli-sensing channels";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050312441.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050311132.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050294072.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050299575.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050309366.1	15	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation"
XP_050296343.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_050313787.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050308647.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050301951.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050292772.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050299498.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050303093.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050300780.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050308996.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050299371.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050302994.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050312387.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050298019.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306545.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050305986.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296174.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050315316.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050301544.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050298843.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050314646.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_050314583.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050295403.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050309501.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050314284.1	5	MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37	"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_050312268.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050309539.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050297176.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050304195.1	4	Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27	"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism"
XP_050297547.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307572.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050299168.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050300872.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-381426;Reactome: R-HSA-8957275	"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation"
XP_050305167.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050294955.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050292857.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050316274.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050295807.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050313613.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050307323.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050312480.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050303917.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050302555.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471	"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_050293399.1	56	Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253	"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex"
XP_050301987.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050300877.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_050310225.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050312931.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050311723.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050295228.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050297840.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050311776.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050297334.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050293872.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050302406.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050293316.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050296671.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050299589.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050310255.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050302421.1	6	Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050308952.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050305868.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314029.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_050299966.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307164.1	18	KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1	"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"(R)-cysteate degradation";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis"
XP_050315105.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050315010.1	4	MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603	"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases"
XP_050308969.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050296976.1	4	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_050313650.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050302012.1	11	Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_050296109.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304806.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050309514.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050309191.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_050298907.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050314040.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_050313420.1	3	Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169	"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis"
XP_050311399.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050311383.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307729.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism"
XP_050301583.1	4	Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-6798695	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Neutrophil degranulation"
XP_050306390.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation"
XP_050292762.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_050298555.1	3	MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4	"Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_050295548.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307904.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050312001.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307791.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050315900.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050298602.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050307897.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050312007.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297802.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-428930	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor"
XP_050298536.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050304092.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050296255.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation"
XP_050301439.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781	"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression"
XP_050295688.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport"
XP_050295595.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050309384.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050310551.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-174411	"Polymerase switching";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere"
XP_050301885.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050316066.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_050310183.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050307770.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050299974.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050310314.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050311378.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050309533.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050295476.1	7	Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1	"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050295848.1	12	MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism"
XP_050307076.1	7	KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_050314620.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_050315651.1	8	MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34	"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
XP_050315502.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050293488.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050311799.1	15	Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665247;Reactome: R-HSA-9634285;Reactome: R-HSA-9665250;Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-9665249;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-9664565;Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810	"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII"
XP_050307783.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297579.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305095.1	3	Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14	"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis"
XP_050313611.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050314146.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050305708.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050313260.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050293271.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050306792.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050307448.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307244.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050312389.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050307047.1	12	Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408	"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_050301783.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050307368.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050296022.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050297725.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050297855.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050307305.1	10	KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS VII - Sly syndrome";"Galactose metabolism";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050297278.1	9	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-901042	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Calnexin/calreticulin cycle"
XP_050315096.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927	"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis"
XP_050315828.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050308445.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050305677.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_050306059.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050303926.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050309579.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050310260.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050304199.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_050295204.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_050296952.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050315935.1	1	Reactome: R-HSA-196108	"Pregnenolone biosynthesis"
XP_050307948.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050300489.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050301519.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_050302396.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050300745.1	15	Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519	"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression"
XP_050295230.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050311299.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050296661.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050313802.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050307957.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050308700.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050314934.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_050306068.1	34	Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"RHO GTPases Activate Formins";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050305130.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050306707.1	60	MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;Reactome: R-HSA-1482798;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5177;Reactome: R-HSA-77305;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00930+4.2.1.17;MetaCyc: PWY-6435;Reactome: R-HSA-77350;Reactome: R-HSA-77285;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-7778;MetaCyc: PWY-7654;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;Reactome: R-HSA-77348;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-5789;MetaCyc: PWY-1361;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5138;MetaCyc: PWY-6944;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;Reactome: R-HSA-77310;MetaCyc: PWY-5109;KEGG: 00281+4.2.1.17+1.1.1.35	"Fatty acid salvage";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Fatty acid degradation";"Acyl chain remodeling of CL";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Benzoate degradation";"Glutaryl-coa degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Caprolactam degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Fatty acid degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Geraniol degradation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Tryptophan metabolism";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"Fatty acid elongation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"Limonene and pinene degradation";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Lysine degradation";"Tryptophan metabolism";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"Geraniol degradation"
XP_050308837.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050303075.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050294245.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050301627.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2"
XP_050313236.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex"
XP_050299169.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050298783.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050312681.1	5	Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_050310286.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050304424.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_050297565.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313514.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050307274.1	5	KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_050314143.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050305743.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050308645.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050312849.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050308061.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_050311020.1	3	Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_050301887.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050306653.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050309473.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening"
XP_050303595.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050305036.1	13	MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7659;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7410	"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis"
XP_050303548.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050315061.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050314220.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050301561.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168333	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"RHO GTPases Activate Formins";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050296589.1	56	Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-75815	"Separation of Sister Chromatids";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D"
XP_050302209.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050295247.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_050313536.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050296710.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_050298545.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050297315.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-8876725	"Respiratory electron transport";"Protein methylation"
XP_050311385.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310307.1	6	Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I"
XP_050305020.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_050302401.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050309300.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050303339.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050297661.1	14	MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00680+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-2201	"Folate polyglutamylation";"Cyanoamino acid metabolism";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine betaine degradation I";"Methane metabolism";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Folate transformations I"
XP_050295248.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_050293946.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050303077.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050305832.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050314193.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050316041.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050297064.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050299212.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050314433.1	12	Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-2122948	"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050301335.1	6	Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_050315102.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050303933.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050306044.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-168315	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Inhibition of Host mRNA Processing and RNA Silencing"
XP_050314813.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8856828	"Nef Mediated CD8 Down-regulation";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Clathrin-mediated endocytosis"
XP_050315480.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050303486.1	6	KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_050303777.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050299284.1	10	MetaCyc: PWY-3821;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"D-galactose detoxification";"Galactose catabolism";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_050316321.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050292999.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules"
XP_050301750.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_050309453.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_050306622.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050297877.1	2	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_050310705.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050310678.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050315238.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050311044.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050294993.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050299590.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_050304644.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050313284.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050302657.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050310087.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050303190.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport"
XP_050292726.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050315888.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050306781.1	1	Reactome: R-HSA-5627083	"RHO GTPases regulate CFTR trafficking"
XP_050308749.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_050306809.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050316164.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050316259.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050300729.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050303368.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050307221.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_050297656.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050302633.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050305806.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_050304816.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050309395.1	2	Reactome: R-HSA-1663150;Reactome: R-HSA-1660662	"The activation of arylsulfatases";"Glycosphingolipid metabolism"
XP_050293808.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050304254.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_050311677.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050312199.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050301510.1	29	Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-77075	"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050298365.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_050301888.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050308448.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_050313259.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050314716.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050295255.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_050305351.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050301949.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050314942.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_050303193.1	11	Reactome: R-HSA-432142;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-9008059;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-391160;Reactome: R-HSA-210990	"Platelet sensitization by LDL";"PD-1 signaling";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin-37 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Signal regulatory protein family interactions";"PECAM1 interactions"
XP_050313843.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050303888.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050311524.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_050308377.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050299369.1	4	MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2;Reactome: R-HSA-70688	"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism";"Proline catabolism"
XP_050305026.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050312070.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050309951.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050298752.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050314267.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050302070.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050298787.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050305928.1	27	Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325	"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"snRNP Assembly";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis"
XP_050308495.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050315376.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050297603.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050295451.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050308823.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050292826.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE"
XP_050311598.1	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050309859.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050316091.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism"
XP_050316192.1	7	KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism"
XP_050302016.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985	"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4"
XP_050306106.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_050307954.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050305007.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050293481.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050306735.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050292959.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050292964.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050307896.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_050314194.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050302201.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176412	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C"
XP_050314083.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696394	"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER"
XP_050306540.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_050300811.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615	"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation"
XP_050310677.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050303018.1	2	Reactome: R-HSA-5627123;Reactome: R-HSA-8856828	"RHO GTPases activate PAKs";"Clathrin-mediated endocytosis"
XP_050300286.1	56	Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178	"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Degradation of DVL";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050298324.1	10	Reactome: R-HSA-1855167;Reactome: R-HSA-983231;Reactome: R-HSA-1855204;MetaCyc: PWY-6365;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6554;MetaCyc: PWY-6366;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159	"Synthesis of pyrophosphates in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system"
XP_050302685.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050311073.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050294059.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050304339.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050313753.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_050301386.1	24	Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-114604;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"Thermogenesis";"Integrin signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"VEGFR2 mediated cell proliferation";"RSK activation";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_050310088.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050311866.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050300203.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050296727.1	26	Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Kinesins";"Aggrephagy";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins"
XP_050306472.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311442.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050309355.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050307598.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050297130.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050306869.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050295534.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050304430.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050294973.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050302217.1	7	MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-882	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_050312188.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050293954.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050302541.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_050307369.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050300147.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050308186.1	5	Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050309559.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_050300804.1	12	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Relaxin signaling pathway";"NRAGE signals death through JNK"
XP_050296421.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050302492.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050316142.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050297729.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050297180.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_050300673.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_050308290.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_050298113.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_050301666.1	18	Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7197	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_050296974.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050311295.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050296207.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050295833.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050302664.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050307061.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050308001.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_050294678.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050311242.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050312069.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236	"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050305737.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050298094.1	5	MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050314365.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050299578.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050296457.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050303015.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050307944.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_050297594.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050300584.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-442720	"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase"
XP_050299627.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_050307204.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050309340.1	9	KEGG: 00360+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5	"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism"
XP_050296178.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_050311998.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306530.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis"
XP_050299325.1	2	KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26	"Starch and sucrose metabolism";"Galactose metabolism"
XP_050312935.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050307707.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050310773.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-8963888;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-8866423;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Chylomicron assembly";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"VLDL assembly";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050294859.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050293778.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050308550.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-9610379	"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"HCMV Late Events"
XP_050315772.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_050312430.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050308170.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050298925.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050308723.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050307838.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050301800.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_050316261.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050305467.1	17	Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16	"Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation"
XP_050305352.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_050300812.1	11	Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_050296809.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_050309023.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050305482.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050304276.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083	"Syndecan interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions"
XP_050314804.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_050307543.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_050301373.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050312151.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050314746.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_050294481.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_050293009.1	4	MetaCyc: PWY-6829;Reactome: R-HSA-2672351;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"Stimuli-sensing channels";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_050304325.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050316217.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050294299.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050295440.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050299153.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050314718.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050304396.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050307622.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050299583.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050300144.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050302731.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050307057.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050295825.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_050303512.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604	"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling"
XP_050299482.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050306403.1	14	MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7279;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1	"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Oxidative phosphorylation"
XP_050303078.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050301522.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_050306608.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050298028.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050307730.1	4	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-8849175;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)"
XP_050311629.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050308192.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158	"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_050308333.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050298756.1	7	Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724	"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription"
XP_050293777.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050316256.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050314239.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050312449.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism"
XP_050313573.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-6807004	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Negative regulation of MET activity"
XP_050311878.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050304554.1	22	MetaCyc: PWY-5384;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8013;MetaCyc: PWY-7347;MetaCyc: PWY-5514;MetaCyc: PWY-621;KEGG: 00500+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-3801;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-6142;MetaCyc: PWY-622;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-6992;MetaCyc: PWY-7385;KEGG: 00010+5.3.1.9;Reactome: R-HSA-6798695	"Sucrose degradation IV (sucrose phosphorylase)";"Glycolysis";"Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"Starch and sucrose metabolism";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)";"Pentose phosphate pathway";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Starch biosynthesis";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"1,5-anhydrofructose degradation";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Neutrophil degranulation"
XP_050296035.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050305255.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050300754.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050308820.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050305681.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_050310271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050313939.1	7	MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-5695;MetaCyc: PWY-7221;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695	"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation"
XP_050308869.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050307609.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050306366.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050294495.1	31	MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;Reactome: R-HSA-163765;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWYG-321;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-5147;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7723;Reactome: R-HSA-9029558;MetaCyc: PWY-6282	"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"Biotin metabolism";"";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)"
XP_050313091.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050300099.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050310042.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050308654.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050312350.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050304706.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050295667.1	8	Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-917977	"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling"
XP_050310457.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050298104.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050313937.1	17	MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765	"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression"
XP_050300544.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050314062.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050298004.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050297973.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050310386.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I"
XP_050298640.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050303138.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311116.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050296103.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314249.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050296052.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050298978.1	18	MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4	"Plasmalogen degradation";"Synthesis of PA";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Arachidonic acid metabolism"
XP_050295832.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050313944.1	17	MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1	"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Pyruvate metabolism";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)"
XP_050308292.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050299262.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050311421.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050295205.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state"
XP_050304999.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050314826.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050295233.1	24	Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050315555.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050315604.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_050313766.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050306159.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050310818.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978	"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"UCH proteinases";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_050303909.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_050296573.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050304587.1	11	MetaCyc: PWY-7124;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-6549	"Ethylene biosynthesis V (engineered)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"Methylaspartate cycle";"L-glutamine biosynthesis III"
XP_050294258.1	14	MetaCyc: PWY-7767;MetaCyc: PWY-5078;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5101	"L-leucine degradation IV (Stickland reaction)";"L-isoleucine degradation II";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II"
XP_050297602.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050309342.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050296817.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050310024.1	5	KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies"
XP_050293507.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050302384.1	14	MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411	"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)"
XP_050316355.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050307834.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050306362.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050301042.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_050306304.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination"
XP_050300127.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050303862.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050297706.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050302644.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050301758.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050306236.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_050311888.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050295094.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050311991.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299758.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_050293413.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050299281.1	10	Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-5609977	"Galactose catabolism";"Galactose metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_050310252.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050314075.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_050297957.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050314642.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050297256.1	3	KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_050302300.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303995.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050301499.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050292727.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_050296639.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050295909.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311368.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050297174.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050297429.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050313472.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050296087.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311130.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050295126.1	3	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins"
XP_050296204.1	7	Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5674400	"Macroautophagy";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050314643.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050295729.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050294829.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050298132.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050295036.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_050316242.1	18	Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167152	"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_050310450.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050306022.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050313357.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_050308000.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050308614.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299982.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050306134.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050299177.1	20	Reactome: R-HSA-9639288;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1	"Amino acids regulate mTORC1";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"HSF1-dependent transactivation";"Macroautophagy";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis"
XP_050303916.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050297438.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050311879.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050316228.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050301737.1	30	Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167161	"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation"
XP_050293093.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050308400.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050307108.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_050303023.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050305383.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050313235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050292718.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050302242.1	4	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"G alpha (i) signalling events";"Ub-specific processing proteases"
XP_050304014.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050315494.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050298279.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050314802.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050306275.1	5	Reactome: R-HSA-8849473;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-1234174;Reactome: R-HSA-1234158	"PTK6 Expression";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cellular response to hypoxia";"Regulation of gene expression by Hypoxia-inducible Factor"
XP_050295698.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050315114.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050294060.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_050312722.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050311893.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_050310601.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050293996.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050309177.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050297822.1	14	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition"
XP_050302266.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050292735.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050312180.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050306757.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050295965.1	13	MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7659	"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Viridicatumtoxin biosynthesis"
XP_050311208.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050316311.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361	"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050308687.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation"
XP_050308761.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050300582.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events"
XP_050294594.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304054.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306309.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311613.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis"
XP_050305015.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8939236;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production"
XP_050293508.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050296747.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050295840.1	11	Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400	"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER"
XP_050302017.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050312859.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050298131.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050301257.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050297597.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050310915.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050307599.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050307238.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050304447.1	10	Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050308633.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050299064.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050314046.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_050293350.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050294764.1	11	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-5689880	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Ub-specific processing proteases"
XP_050310066.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050308357.1	17	Reactome: R-HSA-111448;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-9616222;Reactome: R-HSA-2173796;Reactome: R-HSA-113501;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-1912408;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-69202	"Activation of NOXA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional regulation of granulopoiesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Pre-NOTCH Transcription and Translation";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Cyclin E associated events during G1/S transition"
XP_050315748.1	33	Reactome: R-HSA-69656;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953	"Cyclin A:Cdk2-associated events at S phase entry";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation"
XP_050312360.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050298404.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050310681.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_050309610.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050311446.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050297711.1	9	MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-416476	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events"
XP_050310086.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050308314.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-9609523;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Cargo concentration in the ER";"Intra-Golgi traffic";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_050308721.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050299780.1	6	KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation"
XP_050301409.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050306380.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050306102.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_050294431.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events"
XP_050312967.1	24	Reactome: R-HSA-392517;Reactome: R-HSA-164378;Reactome: R-HSA-9634600;Reactome: R-HSA-5621575;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-4420097;Reactome: R-HSA-8853659;Reactome: R-HSA-5687128;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610783;Reactome: R-HSA-422356;Reactome: R-HSA-442720;Reactome: R-HSA-5610780;Reactome: R-HSA-9010642;Reactome: R-HSA-5610785;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163358;Reactome: R-HSA-111931;Reactome: R-HSA-163615	"Rap1 signalling";"PKA activation in glucagon signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"CD209 (DC-SIGN) signaling";"HDL assembly";"Triglyceride catabolism";"VEGFA-VEGFR2 Pathway";"RET signaling";"MAPK6/MAPK4 signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI2 by the proteasome";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI1 by the proteasome";"ROBO receptors bind AKAP5";"GLI3 is processed to GLI3R by the proteasome";"mTOR signaling pathway";"PKA-mediated phosphorylation of key metabolic factors";"PKA-mediated phosphorylation of CREB";"PKA activation"
XP_050302561.1	4	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050315628.1	20	KEGG: 00020+2.3.3.8;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;Reactome: R-HSA-163765;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-75105	"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Fatty acyl-CoA biosynthesis"
XP_050304947.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050307165.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050307302.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050313082.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050314030.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050306502.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050307652.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050306063.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050302756.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380284;Reactome: R-HSA-380320	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes"
XP_050294045.1	10	MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis"
XP_050296115.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305783.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172	"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome"
XP_050307581.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-216083	"Laminin interactions";"Anchoring fibril formation";"Collagen chain trimerization";"Collagen degradation";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Signaling by PDGF";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions"
XP_050315072.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_050309890.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050296935.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050302111.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_050293868.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050309849.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050298749.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050312618.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050296287.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050314174.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050300277.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050304500.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050301222.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050303490.1	10	KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_050298675.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050306856.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050295305.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050306930.1	14	Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169	"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis"
XP_050312416.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050310519.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050310806.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050299680.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_050314172.1	5	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_050315131.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050305150.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_050300517.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_050305926.1	27	Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_050303114.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050300030.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005	"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport"
XP_050312184.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050298269.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050292972.1	12	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules"
XP_050295672.1	14	Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8052;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4	"Synthesis of PC";"Synthesis of PE";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"Ether lipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_050311931.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050308260.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis"
XP_050314067.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050293372.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050307025.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_050294582.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050294890.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050303843.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050292711.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050293971.1	11	Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"DNA replication initiation";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050298894.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_050300477.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050309319.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050300931.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_050302394.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050297581.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050307713.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050307276.1	5	MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050299593.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050294470.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050296743.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050309763.1	18	KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6643;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1	"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Coenzyme M biosynthesis II";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis"
XP_050300006.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050296772.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_050296441.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_050315566.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;Reactome: R-HSA-5579006	"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)"
XP_050314292.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050304352.1	14	Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638	"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_050299431.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418597;Reactome: R-HSA-6814122	"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050305053.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis"
XP_050304969.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050295311.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050295229.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050298039.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050310520.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050315476.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050313785.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050313965.1	5	MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_050295185.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050298310.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050315970.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050310227.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050292975.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050301388.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304551.1	2	Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14	"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_050293400.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_050300669.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050296917.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050306913.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050301218.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_050298114.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_050303546.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050299183.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050293829.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238	"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation"
XP_050298273.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050297573.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304338.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_050293266.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050312831.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_050312231.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050294428.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050301458.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311790.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050293875.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050308189.1	26	Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300	"Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"SUMOylation of transcription cofactors"
XP_050311881.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744	"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation"
XP_050307364.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050305165.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050314015.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050301143.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050312939.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050311605.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-8940973	"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"RUNX2 regulates osteoblast differentiation"
XP_050294838.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_050298807.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050294795.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050316362.1	6	MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050308740.1	9	Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex"
XP_050311794.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes"
XP_050314868.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050309988.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_050303081.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050308661.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050309955.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787	"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state"
XP_050308988.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050302659.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_050307947.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1"
XP_050303498.1	4	KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050298893.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050308312.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050314880.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050303254.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050297972.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050299891.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050307806.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050296720.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050301392.1	6	KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23	"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism"
XP_050311301.1	10	Reactome: R-HSA-2151201;Reactome: R-HSA-111459;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069	"Transcriptional activation of mitochondrial biogenesis";"Activation of caspases through apoptosome-mediated cleavage";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity"
XP_050304226.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050311867.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050294474.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_050304869.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050305250.1	20	MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-5136	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_050300867.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_050299499.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981	"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III"
XP_050314879.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050315468.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050308204.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050308873.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050303196.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050297613.1	10	KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-69205;Reactome: R-HSA-499943;MetaCyc: PWY-7199;MetaCyc: PWY-7184;KEGG: 00670+2.1.1.45;MetaCyc: PWY-3841	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"G1/S-Specific Transcription";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"One carbon pool by folate";"Folate transformations II (plants)"
XP_050299331.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050307971.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050300808.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050305163.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050297724.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050313762.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050303382.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_050310268.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050305016.1	3	Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Nuclear Receptor transcription pathway"
XP_050304111.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HCMV Early Events"
XP_050302922.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050310022.1	7	KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4	"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Mevalonate degradation";"Synthesis and degradation of ketone bodies"
XP_050304137.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050312351.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050298374.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398	"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway"
XP_050309201.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050306785.1	21	MetaCyc: PWY-7220;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7176;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7219;MetaCyc: PWY-7226;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050315336.1	42	Reactome: R-HSA-110330;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-8936459;Reactome: R-HSA-3214858;Reactome: R-HSA-110328;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-606279;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-977225;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-212300;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-201722	"Recognition and association of DNA glycosylase with site containing an affected purine";"Estrogen-dependent gene expression";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Deposition of new CENPA-containing nucleosomes at the centromere";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"Meiotic synapsis";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Meiotic recombination";"DNA methylation";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"Amyloid fiber formation";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"PRC2 methylates histones and DNA";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex"
XP_050307469.1	5	KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817	"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_050314303.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_050305847.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050312135.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050310735.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_050314665.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_050304016.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050305896.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_050295990.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050294158.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050310043.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_050312697.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050301420.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism"
XP_050312003.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300039.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_050310823.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050303670.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050312417.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050304318.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050295622.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300802.1	12	Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"NRAGE signals death through JNK";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050314076.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_050307831.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050311432.1	4	Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532	"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer"
XP_050296166.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-6785807;Reactome: R-HSA-8854691	"T cell receptor signaling pathway";"Interleukin-4 and Interleukin-13 signaling";"Interleukin-20 family signaling"
XP_050315542.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050301494.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050297571.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301652.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050308494.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050294808.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050304117.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050312341.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050300728.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050293236.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_050306621.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050311354.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_050312369.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_050309605.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050308763.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-176187	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress"
XP_050311746.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6782315	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"tRNA modification in the nucleus and cytosol"
XP_050293951.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050306091.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050314085.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_050311328.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050310874.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050311178.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050297881.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050296118.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050313422.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050310075.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050307755.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050296079.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_050309502.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050308200.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050305460.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050311743.1	14	Reactome: R-HSA-1474151;Reactome: R-HSA-6811438;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;Reactome: R-HSA-204005;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-6811434;MetaCyc: PWY-5663;MetaCyc: PWY-7852;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Intra-Golgi traffic";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"COPII-mediated vesicle transport";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Threo-tetrahydrobiopterin biosynthesis"
XP_050302425.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050312976.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050305092.1	10	KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.153;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276	"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)"
XP_050313782.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050293112.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050298788.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050315275.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050307883.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050302964.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050308704.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050301731.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050304834.1	3	Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243	"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050312830.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782	"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Plasmalogen biosynthesis"
XP_050303583.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_050305533.1	12	Reactome: R-HSA-71240;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13	"Tryptophan catabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Selenocompound metabolism"
XP_050296135.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305738.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050312916.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-6803	"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing"
XP_050297459.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938	"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)"
XP_050315062.1	18	KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism"
XP_050306460.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_050314483.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050310157.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_050314363.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050300970.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050310401.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050293732.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050293500.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050295785.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050297668.1	8	Reactome: R-HSA-4641263;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-8856825;Reactome: R-HSA-4086398;Reactome: R-HSA-5340588;Reactome: R-HSA-4608870	"Regulation of FZD by ubiquitination";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Cargo recognition for clathrin-mediated endocytosis";"Ca2+ pathway";"RNF mutants show enhanced WNT signaling and proliferation";"Asymmetric localization of PCP proteins"
XP_050301934.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050308068.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050300917.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050309151.1	3	KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807	"Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)"
XP_050313149.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050304101.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050299062.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050305157.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050302229.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_050295925.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294125.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050294870.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050305418.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050298510.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050305235.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050309597.1	10	Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_050306971.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050306313.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050312739.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_050314047.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_050316023.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_050304139.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050292957.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050312848.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050303092.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis"
XP_050294437.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050294029.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_050297072.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001	"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade"
XP_050298259.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-5689880	"Ovarian tumor domain proteases";"Ub-specific processing proteases"
XP_050304498.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050308462.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050305791.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050303584.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214815	"NoRC negatively regulates rRNA expression";"HDACs deacetylate histones"
XP_050313136.1	7	MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25	"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism"
XP_050302400.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050308677.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050307972.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560	"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism"
XP_050308973.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121	"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Translesion synthesis by POLI"
XP_050303665.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050312012.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050296769.1	9	Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6385;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;MetaCyc: PWY-6470	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)"
XP_050311997.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306652.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050314465.1	6	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050313715.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050298228.1	4	KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817	"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_050305169.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050305512.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_050308155.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050297118.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-936837	"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases"
XP_050307815.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050301210.1	3	KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684	"Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism"
XP_050314577.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_050302290.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050302656.1	27	Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377	"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Late Events";"snRNP Assembly";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins"
XP_050298325.1	10	MetaCyc: PWY-6366;MetaCyc: PWY-6554;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.134+2.7.1.159;KEGG: 04070+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;Reactome: R-HSA-983231;Reactome: R-HSA-1855167	"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol"
XP_050313763.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050307010.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050310073.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050298754.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050301745.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination"
XP_050297074.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050296346.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-9630222	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding"
XP_050297666.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050301333.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050303882.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_050295371.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050302670.1	6	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-983168;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Budding and maturation of HIV virion"
XP_050312052.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050304023.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-2644606	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050311612.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050312850.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050313996.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway"
XP_050294510.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050295439.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050303235.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050309051.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050297284.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050295883.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050298750.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050295808.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050298830.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050305389.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050308634.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050303927.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050308522.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050306240.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_050314896.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050304513.1	11	Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6596;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6538	"Purine catabolism";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Purine metabolism";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Theophylline degradation";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)"
XP_050302721.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050303920.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050303553.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_050293807.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050292995.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_050293869.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050305694.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050312269.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050304121.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy"
XP_050308450.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_050311022.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms"
XP_050309982.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_050308375.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050299580.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050298729.1	13	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"mTOR signalling";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Macroautophagy"
XP_050299984.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050297287.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050308179.1	16	Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409	"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A"
XP_050293519.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050305366.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050316301.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism"
XP_050302788.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050311131.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050313068.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050312402.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050311672.1	5	Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)"
XP_050315147.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050307731.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_050315330.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050301159.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism"
XP_050310608.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050301956.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297275.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_050314200.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050309778.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation"
XP_050301689.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050296519.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050301644.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050299678.1	7	MetaCyc: PWY-3561;Reactome: R-HSA-1483166;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4	"Choline biosynthesis III";"Synthesis of PA";"Ether lipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism"
XP_050296907.1	8	KEGG: 00630+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7733;MetaCyc: PWY-7734;MetaCyc: PWY-7765	"Glyoxylate and dicarboxylate metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_050299199.1	7	Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661	"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_050316298.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050307711.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_050306062.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298801.1	10	MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Folate transformations I";"L-histidine degradation III";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes"
XP_050305338.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_050314008.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050314594.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050314059.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050304655.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050312455.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050300809.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670	"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Purine metabolism";"Adenylate cyclase inhibitory pathway"
XP_050303141.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050297575.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299238.1	2	Reactome: R-HSA-352230;Reactome: R-HSA-442660	"Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters"
XP_050296385.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050295926.1	13	KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5497;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-1722;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9	"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_050296083.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050315509.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050305329.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation"
XP_050294992.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_050312843.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_050313872.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050316263.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050308519.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050296427.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050298277.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050304113.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation"
XP_050308785.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050295589.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302224.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050303820.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_050298965.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302303.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050297794.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050312822.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883	"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II"
XP_050296211.1	9	KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II"
XP_050299304.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050300766.1	9	Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_050296814.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050313837.1	3	Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426	"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050300727.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050309769.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050313870.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050295700.1	6	Reactome: R-HSA-1483166;MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148	"Synthesis of PA";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PG"
XP_050308289.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097	"T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway"
XP_050295604.1	15	MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis"
XP_050315568.1	5	KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_050312550.1	5	MetaCyc: PWY-7918;Reactome: R-HSA-4793954;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668	"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050306834.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050313789.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050313781.1	5	Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897	"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes"
XP_050304446.1	10	Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation"
XP_050294861.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050305869.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050293380.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050296746.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050294830.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050303032.1	8	KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1	"Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism"
XP_050305558.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050293077.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050312465.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050296692.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314558.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050308603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307744.1	6	Reactome: R-HSA-1660499;MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580	"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)"
XP_050293618.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050294812.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress"
XP_050298258.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050296608.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_050307015.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_050301650.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050297663.1	14	MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-2201;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-3661;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1	"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Folate transformations I";"Glycine, serine and threonine metabolism";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate"
XP_050312358.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050302402.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050297882.1	1	Reactome: R-HSA-8953750	"Transcriptional Regulation by E2F6"
XP_050296239.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism"
XP_050296598.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050314004.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis"
XP_050293931.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050299399.1	31	MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-7663;MetaCyc: PWY-7858;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-5147;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-8012	"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Mupirocin biosynthesis"
XP_050316337.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050311874.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050296101.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294585.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050313353.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050294511.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050306196.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69601	"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_050305358.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050314095.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_050313838.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_050296113.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050292850.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050310789.1	6	Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-7285	"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis"
XP_050299180.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050304770.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_050299566.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050301419.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22	"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050314525.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050308586.1	6	Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050314545.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050303973.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_050298858.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050297527.1	17	Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-8951664	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Neddylation"
XP_050295680.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050293643.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_050301095.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301418.1	6	MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820	"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_050299569.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050295618.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050294885.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_050310892.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050307058.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050305234.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050313622.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050309380.1	3	KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590	"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation"
XP_050306295.1	15	Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402	"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex"
XP_050298944.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050296531.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050301460.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050306847.1	16	Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-6785631;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1963640	"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"ERBB2 Regulates Cell Motility";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"GRB2 events in ERBB2 signaling"
XP_050301331.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050300837.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_050303896.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050314574.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050298447.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050312165.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_050296067.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303224.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
XP_050297458.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568	"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050310150.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050314614.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050296921.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050293003.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_050306402.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7279;MetaCyc: PWY-7254;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561	"Oxidative phosphorylation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050296694.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314443.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_050315344.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050311984.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306160.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050302324.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050306384.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_050298074.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293790.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312071.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-210746	"Regulation of gene expression in beta cells";"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells"
XP_050297550.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314719.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050294012.1	6	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism"
XP_050310622.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050292880.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050309365.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_050303895.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050305936.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050312736.1	3	Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669	"Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_050296818.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050299900.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050308194.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_050303144.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050314356.1	7	Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11	"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway"
XP_050304411.1	7	Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-203927	"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis"
XP_050298177.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050301753.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050307579.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157	"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Collagen degradation";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Anchoring fibril formation";"Laminin interactions"
XP_050294869.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050312164.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050308002.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050315581.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_050305323.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050311989.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297511.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050311090.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_050313966.1	11	KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway"
XP_050296580.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050305152.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050305988.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298073.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050293692.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis"
XP_050307556.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_050309103.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312393.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050308715.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050315334.1	42	Reactome: R-HSA-110331;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-977225;Reactome: R-HSA-912446;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-73728;Reactome: R-HSA-9609690;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-9610379;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-606279	"Cleavage of the damaged purine";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Amyloid fiber formation";"Meiotic recombination";"DNA methylation";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Opening";"HCMV Early Events";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"HCMV Late Events";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050306619.1	5	KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_050308345.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_050305160.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050313726.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050314892.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050299681.1	7	MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282	"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_050310668.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs"
XP_050314844.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050308475.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050296092.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298544.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050311826.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050316367.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_050313244.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050312851.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050314484.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050303876.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050293417.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050298407.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050297820.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_050313380.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_050294862.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050304119.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050293012.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638	"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins"
XP_050300794.1	3	MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_050309772.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050295679.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_050308216.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050296562.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298958.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050308163.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050302376.1	7	KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213	"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Synthesis of PC";"Synthesis of PE"
XP_050308415.1	6	Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_050302729.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050299555.1	15	Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends"
XP_050310419.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050301019.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228	"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix"
XP_050304249.1	5	Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211981;Reactome: R-HSA-211976	"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Xenobiotics";"Endogenous sterols"
XP_050312377.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050306241.1	9	MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle"
XP_050311042.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex"
XP_050306553.1	10	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_050299404.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050302084.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex"
XP_050301908.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_050300032.1	16	Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050308548.1	9	MetaCyc: PWY-241;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-5743	"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle"
XP_050299744.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050301229.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050313616.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050298599.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050301815.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050314370.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050305430.1	40	Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167246	"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript"
XP_050315475.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050296922.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050296296.1	10	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-156827;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"L13a-mediated translational silencing of Ceruloplasmin expression";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050295188.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050312399.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050315813.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_050308384.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050310094.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050304323.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_050298747.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050294723.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050309391.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050298319.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050298824.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333	"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_050309599.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050294975.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050308521.1	6	KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;Reactome: R-HSA-913709	"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins"
XP_050298850.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050293255.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage"
XP_050305052.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050297141.1	19	Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Ion homeostasis";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity"
XP_050315656.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050305051.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels"
XP_050304247.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050310682.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050312405.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050294308.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050315775.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_050313002.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_050298575.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050299264.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050298040.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050310774.1	11	Reactome: R-HSA-73776;Reactome: R-HSA-8963888;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-8866423;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"Chylomicron assembly";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"VLDL assembly";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050309580.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050297085.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300	"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion homeostasis";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling"
XP_050301700.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050308525.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050304634.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050314375.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_050304646.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050313314.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050315326.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050298012.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050301701.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050299154.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296161.1	28	Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5696395;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169	"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Formation of Incision Complex in GG-NER";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"HSF1 activation";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis"
XP_050315567.1	5	KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403	"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling"
XP_050313694.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050300771.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167161	"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation"
XP_050294515.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050293351.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_050299592.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6	"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism"
XP_050307570.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050308048.1	29	Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-68962;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5696395;Reactome: R-HSA-912446	"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Activation of the pre-replicative complex";"HSF1 activation";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of Incision Complex in GG-NER";"Meiotic recombination"
XP_050294813.1	4	Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-111465	"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins"
XP_050306609.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_050310005.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050311329.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050298042.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4641258	"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Degradation of DVL"
XP_050294715.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050314171.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_050294069.1	22	Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5675221	"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Negative regulation of MAPK pathway"
XP_050301923.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050308578.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_050297124.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571	"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation"
XP_050307684.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050294238.1	8	MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268	"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_050295434.1	5	Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-933541	"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation"
XP_050313087.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050294531.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050298137.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_050307168.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_050294339.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050296469.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_050311990.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295991.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050309687.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050303430.1	6	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;MetaCyc: PWY-6749;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_050302802.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050302479.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050315614.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050297727.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_050313786.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050305904.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050301048.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050306600.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050299894.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380284	"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050305104.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050314708.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050305742.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050308651.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050312701.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050312325.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050301129.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_050310553.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation"
XP_050306650.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_050307437.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050296595.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7601;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7053;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598;KEGG: 00062+4.2.1.134	"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Fatty acid elongation"
XP_050311445.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050299598.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050310724.1	3	MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662	"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism"
XP_050294840.1	1	Reactome: R-HSA-1234174	"Cellular response to hypoxia"
XP_050300664.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050302920.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_050312915.1	14	MetaCyc: PWY-8053;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;Reactome: R-HSA-1482788	"Anandamide biosynthesis II";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC"
XP_050300592.1	18	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7220	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_050308340.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050298871.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_050316029.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Glycerolipid metabolism"
XP_050310962.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050302063.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050299585.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050300948.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314065.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050316193.1	7	KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22	"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_050298803.1	10	KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-3841;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-6613	"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"L-histidine degradation III";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_050298660.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050299651.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52	"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_050302983.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294144.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050298141.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-6842	"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II"
XP_050309585.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050303581.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050301469.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050310613.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050300672.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_050296020.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050303147.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050310459.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050312424.1	3	Reactome: R-HSA-111471;Reactome: R-HSA-9645722;Reactome: R-HSA-140837	"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation"
XP_050314757.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050311904.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050296039.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050304627.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050315049.1	6	Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_050305232.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050297479.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_050313292.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050305233.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050295074.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050296466.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050308764.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_050295067.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050296965.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050306482.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050308953.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050304055.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050309767.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050295222.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_050301508.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050305485.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050308714.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050303208.1	11	Reactome: R-HSA-512988;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-912694;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-388841	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interferon alpha/beta signaling";"PD-1 signaling";"Platelet sensitization by LDL";"Regulation of IFNA signaling";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"PECAM1 interactions";"Regulation of IFNG signaling";"Costimulation by the CD28 family"
XP_050313505.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)"
XP_050293170.1	33	MetaCyc: PWY-5078;MetaCyc: PWY-7111;Reactome: R-HSA-71384;MetaCyc: PWY-7013;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-7396;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-5057;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-5076;MetaCyc: PWY-6871;KEGG: 00260+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-6802;MetaCyc: PWY-7118;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5486;KEGG: 00680+1.1.1.284;MetaCyc: PWY-3162;MetaCyc: PWY-1801;MetaCyc: PWY-5082;MetaCyc: PWY-6587;MetaCyc: PWY-5751	"L-isoleucine degradation II";"Pyruvate fermentation to isobutanol (engineered)";"Ethanol oxidation";"(S)-propane-1,2-diol degradation";"Naphthalene degradation";"Protein S-nitrosylation and denitrosylation";"Butanol and isobutanol biosynthesis (engineered)";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Glycolysis / Gluconeogenesis";"Noradrenaline and adrenaline degradation";"L-valine degradation II";"Chloroalkane and chloroalkene degradation";"Serotonin degradation";"L-leucine degradation III";"3-methylbutanol biosynthesis (engineered)";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"alpha-Linolenic acid metabolism";"Drug metabolism - cytochrome P450";"Acetaldehyde biosynthesis I";"Salidroside biosynthesis";"Chitin degradation to ethanol";"Fatty acid degradation";"L-phenylalanine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol II";"Methane metabolism";"L-tryptophan degradation V (side chain pathway)";"Formaldehyde oxidation II (glutathione-dependent)";"L-methionine degradation III";"Pyruvate fermentation to ethanol III";"Phenylethanol biosynthesis"
XP_050313238.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050311590.1	4	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050298142.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050297068.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050295588.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300452.1	9	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Thermogenesis"
XP_050301589.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_050295104.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050313365.1	13	KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosaminoglycan degradation"
XP_050307363.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050310546.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-171319	"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase"
XP_050299895.1	12	Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6807878	"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport"
XP_050297359.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050301075.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050306775.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_050309222.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050314557.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_050314460.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050298908.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050316397.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050308962.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050304645.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050294931.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050316030.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050313445.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050302476.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050309445.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_050306736.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050314256.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050300916.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050316365.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050294457.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050308378.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050300800.1	12	Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"NRAGE signals death through JNK";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (q) signalling events";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050311568.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050312691.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050310539.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-112382	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex"
XP_050304220.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050296122.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297654.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050293602.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050309192.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Chromatin modifying enzymes"
XP_050295522.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
XP_050312388.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050310631.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050297710.1	9	Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_050311846.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050307227.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050314422.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050316146.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050314681.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050293063.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_050296958.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050298368.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927	"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis"
XP_050312861.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050311243.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling"
XP_050298678.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050311660.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050316045.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050300095.1	29	Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-73772	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape"
XP_050296171.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25	"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050311140.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050304324.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_050311386.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310403.1	2	Reactome: R-HSA-977225;Reactome: R-HSA-8854214	"Amyloid fiber formation";"TBC/RABGAPs"
XP_050302011.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050303863.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050316069.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050313509.1	8	MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168	"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)"
XP_050311096.1	12	KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4	"Ether lipid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism"
XP_050305758.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050308526.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050306846.1	16	Reactome: R-HSA-6785631;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1963642;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1236394;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-1250342;Reactome: R-HSA-1257604	"ERBB2 Regulates Cell Motility";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PI3K events in ERBB2 signaling";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB4";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB4 signaling";"PIP3 activates AKT signaling"
XP_050308668.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_050301231.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050312971.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050303085.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050309531.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_050308752.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050299319.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050301410.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050293865.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_050304114.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_050293308.1	15	MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-6142;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-5723	"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt"
XP_050309435.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050306256.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050309301.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_050292835.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis"
XP_050299474.1	37	Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-2132295;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-983170;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-204005	"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"MHC class II antigen presentation";"snRNP Assembly";"HCMV Late Events";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"COPII-mediated vesicle transport"
XP_050316255.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050296041.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050315469.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050310885.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050296468.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation"
XP_050301789.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050309643.1	4	KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050300356.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050299908.1	9	MetaCyc: PWY-5743;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_050307453.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050299600.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050305799.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050298626.1	5	Reactome: R-HSA-193048;MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94	"Androgen biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_050303259.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050309475.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050305107.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050306618.1	5	KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_050295996.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050298213.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane"
XP_050295919.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050308881.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_050302083.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis"
XP_050305872.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050314013.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050298639.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050303349.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050315647.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_050302478.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_050295138.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050314500.1	4	MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32	"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism"
XP_050307975.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050293256.1	5	KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621	"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism"
XP_050297046.1	19	Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5673001	"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion homeostasis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade"
XP_050304448.1	10	Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_050293397.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050300951.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_050311870.1	9	Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-196780;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050301685.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050302227.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665	"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells"
XP_050304189.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050302085.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_050293392.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167290	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation"
XP_050296209.1	9	KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52	"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation"
XP_050303405.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050308392.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050308129.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4085377	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins"
XP_050306850.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_050307895.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050298926.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050296082.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_050302195.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050312863.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle"
XP_050294435.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050311152.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050313842.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050309478.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050314324.1	7	KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204	"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_050311909.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_050300058.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050295462.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_050296130.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299645.1	5	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism"
XP_050296110.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314296.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050311115.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050315764.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050309602.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296097.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312203.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050316092.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268	"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_050313233.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050303931.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050301658.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050293972.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_050316325.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050314045.1	6	MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;MetaCyc: PWY-5067	"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_050307349.1	13	KEGG: 00230+3.6.1.66;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;Reactome: R-HSA-74259;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Tunicamycin biosynthesis"
XP_050311891.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296833.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050293304.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6886	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)"
XP_050311803.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050313903.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination"
XP_050310822.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_050313950.1	17	MetaCyc: PWY-6722;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;Reactome: R-HSA-200425;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;KEGG: 00254+6.4.1.2;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Aflatoxin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism"
XP_050299273.1	31	MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5973;MetaCyc: PWY-6519;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5971;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-7664;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-8047;Reactome: R-HSA-199220;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-6282;Reactome: R-HSA-9029558	"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"";"Biotin metabolism";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis IV (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bryostatin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis"
XP_050306078.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC"
XP_050307952.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_050302099.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_050306833.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_050314441.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway"
XP_050299063.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050304799.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade"
XP_050299746.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050307710.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050307414.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050298870.1	8	Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER"
XP_050307278.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_050307033.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050311397.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050303805.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050296596.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_050295253.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050297790.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050	"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hedgehog 'on' state";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_050296613.1	9	Reactome: R-HSA-2173789;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279	"TGF-beta receptor signaling activates SMADs";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer"
XP_050302240.1	4	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-418594	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"G alpha (i) signalling events"
XP_050301582.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050311017.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050297473.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_050303913.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050312853.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050313070.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050314192.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050314544.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050295223.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_050311791.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050308293.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050308598.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050293274.1	11	MetaCyc: PWY-381;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963	"Nitrate reduction II (assimilatory)";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I"
XP_050296383.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050299967.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302019.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050304779.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050297788.1	57	Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128	"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling"
XP_050301478.1	6	KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66	"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system"
XP_050308284.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_050302495.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050306121.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050299753.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050307551.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050306463.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050315975.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050294472.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050312884.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by Hippo";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050306381.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_050306867.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_050299265.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050293874.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050309336.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050315513.1	12	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Relaxin signaling pathway";"Macroautophagy";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_050312711.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_050309647.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050316317.1	4	Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011	"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance"
XP_050297762.1	5	Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684	"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state"
XP_050297908.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-7199;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181	"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation"
XP_050306230.1	10	Reactome: R-HSA-9022699;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-8936459	"MECP2 regulates neuronal receptors and channels";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050302488.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050306147.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050308449.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_050303406.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050297094.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Ion homeostasis";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050314451.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-7382;MetaCyc: PWY-6987	"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_050296640.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050299672.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050308409.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050297355.1	42	Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-427413;Reactome: R-HSA-2299718;Reactome: R-HSA-2559586;Reactome: R-HSA-212300	"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"HDACs deacetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"DNA methylation";"Meiotic recombination";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"NoRC negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"DNA Damage/Telomere Stress Induced Senescence";"PRC2 methylates histones and DNA"
XP_050304104.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050310670.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_050293715.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050303570.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_050314509.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050307372.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050299914.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050312397.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050308196.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302673.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050307081.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050297850.1	8	MetaCyc: PWY-4661;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-2301;MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism"
XP_050311708.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050312272.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_050301370.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050303766.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050312207.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050310813.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050315911.1	4	Reactome: R-HSA-447043;Reactome: R-HSA-373760;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096	"Neurofascin interactions";"L1CAM interactions";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_050295516.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050312460.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050314579.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050295997.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_050310739.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-9646399	"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Aggrephagy"
XP_050309390.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050295479.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050310600.1	12	MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133	"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Colupulone and cohumulone biosynthesis"
XP_050311970.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298927.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662	"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism"
XP_050295827.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050314170.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_050293724.1	13	KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883	"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II"
XP_050294934.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050296923.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050300119.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050314865.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050315894.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050293804.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050313744.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050295382.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050310763.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050313770.1	40	Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-8851708;Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-72203	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Signaling by FGFR2 IIIa TM";"mRNA Capping";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA"
XP_050308868.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050304300.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050310215.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050299307.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050293345.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050293039.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050308082.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050304326.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_050302320.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050309323.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050301354.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_050294241.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_050307079.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050301719.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050300140.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050294739.1	7	MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6351	"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_050295441.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_050303866.1	4	KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;MetaCyc: PWY-8040;MetaCyc: PWY-7383	"D-Alanine metabolism";"Alanine racemization";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050305019.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_050308433.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_050305170.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050304170.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050299998.1	3	Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50	"MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation"
XP_050313474.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050298875.1	8	Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Dual incision in TC-NER"
XP_050314707.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050312418.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050300825.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050301319.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050314257.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050313291.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050303446.1	5	Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-9646399	"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy"
XP_050314073.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690	"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events"
XP_050294403.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_050303366.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050294475.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294	"SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors"
XP_050310659.1	3	Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078	"Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)"
XP_050293225.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_050299642.1	2	Reactome: R-HSA-75105;Reactome: R-HSA-383280	"Fatty acyl-CoA biosynthesis";"Nuclear Receptor transcription pathway"
XP_050305776.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050296945.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050303657.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_050296256.1	2	Reactome: R-HSA-156581;Reactome: R-HSA-72764	"Methylation";"Eukaryotic Translation Termination"
XP_050311393.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310889.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-3928662	"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling"
XP_050294976.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050305390.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050315901.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050294867.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305341.1	2	Reactome: R-HSA-5635838;Reactome: R-HSA-5632681	"Activation of SMO";"Ligand-receptor interactions"
XP_050305000.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050304521.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050303484.1	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_050299167.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050300795.1	3	MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1	"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation"
XP_050303919.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050309026.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050301808.1	13	MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;MetaCyc: PWY-5133;Reactome: R-HSA-71384;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1	"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Ethanol oxidation";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes"
XP_050314087.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050313084.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050294496.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050305893.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050303191.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895	"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis"
XP_050300751.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050299844.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050315670.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050301883.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_050303828.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050295018.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"HDACs deacetylate histones"
XP_050300416.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050311297.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050313092.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050312293.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050311494.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050313533.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307998.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050296382.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050306854.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050299125.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050311985.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050293254.1	5	Reactome: R-HSA-73614;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532	"Pyrimidine salvage";"Pyrimidine catabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)"
XP_050315834.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050309764.1	12	Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-5250924;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-3214847;Reactome: R-HSA-210744	"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_050309660.1	4	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050307549.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling"
XP_050301389.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_050298433.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050307573.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050305534.1	12	MetaCyc: PWY-6309;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-601;MetaCyc: PWY-801;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-1187;MetaCyc: PWY-6936	"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Selenocompound metabolism";"Tryptophan metabolism";"Glucosinolate biosynthesis from homomethionine";"Seleno-amino acid biosynthesis (plants)"
XP_050305162.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation"
XP_050302672.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050298139.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_050312192.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050312294.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_050307611.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_050304930.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-5136	"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)"
XP_050312735.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_050306128.1	2	Reactome: R-HSA-5633231;Reactome: R-HSA-446193	"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050311999.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050295730.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050309182.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050315631.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_050311972.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298714.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050304964.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050306124.1	6	KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-2942;MetaCyc: PWY-5097;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7	"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"L-lysine biosynthesis VI";"Dipicolinate biosynthesis";"Monobactam biosynthesis"
XP_050297361.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050302124.1	2	Reactome: R-HSA-2173788;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"UCH proteinases"
XP_050311889.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050302405.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050308406.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_050297356.1	8	MetaCyc: PWY-5;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5154;MetaCyc: PWY-4983;MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400	"Canavanine biosynthesis";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)"
XP_050315762.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050306705.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis"
XP_050295418.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050311800.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050295912.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050312004.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312608.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050299409.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050293609.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471	"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_050312726.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050310595.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050295279.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_050313287.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis"
XP_050305757.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_050306890.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895	"Alanine, aspartate and glutamate metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_050308970.1	3	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1"
XP_050297182.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_050299327.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_050292717.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050306148.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050303858.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050308257.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_050315097.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050311104.1	12	MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_050292738.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-4641257	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Degradation of AXIN"
XP_050294486.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050300085.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050297493.1	52	Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167290	"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation"
XP_050315137.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050315846.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050311885.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_050296691.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050302895.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_050293329.1	10	Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-983168	"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050305875.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050305168.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050294684.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050304405.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050296372.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050310060.1	5	Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;MetaCyc: PWY-5046	"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_050300835.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_050297693.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050311959.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304260.1	6	MetaCyc: PWY-2221;MetaCyc: PWY-5530;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Caprolactam degradation"
XP_050304168.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050303698.1	10	Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050313248.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050303804.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050298270.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050311094.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism"
XP_050301985.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050315779.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050301050.1	5	MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821	"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification"
XP_050315924.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-5617472	"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_050313100.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-442982	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_050305844.1	3	MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450	"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion"
XP_050309783.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050294389.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_050294917.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050307174.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684	"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"UCH proteinases";"Hedgehog 'on' state"
XP_050303365.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050314383.1	11	Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-975634	"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport"
XP_050296258.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050292976.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050296584.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050303358.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050312846.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050302621.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050313967.1	11	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-4420097	"Human papillomavirus infection";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"p38MAPK events";"VEGFA-VEGFR2 Pathway"
XP_050300726.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050314068.1	7	Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836	"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis"
XP_050309811.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050312740.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050295467.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050296968.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050310250.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050296543.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050303379.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050297318.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050313761.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050301957.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050301645.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_050306306.1	7	Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Meiotic synapsis";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine"
XP_050302998.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_050303962.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050296914.1	1	MetaCyc: PWY-6771	"Rhamnogalacturonan type I degradation II (bacteria)"
XP_050302036.1	9	MetaCyc: PWY-1042;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
XP_050315511.1	7	MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-5083;Reactome: R-HSA-6799198;MetaCyc: PWY-6692	"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Complex I biogenesis";"Fe(II) oxidation"
XP_050296996.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_050292771.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050300450.1	9	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_050305388.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050301973.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_050316250.1	33	Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-69231;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-76042;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-77075	"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Transcription of the HIV genome";"Cyclin D associated events in G1";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_050300226.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050307109.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_050310797.1	8	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"T cell receptor signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050314798.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_050315561.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050304817.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050296212.1	6	Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3	"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Purine metabolism"
XP_050293714.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050316219.1	56	Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813	"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Degradation of DVL";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Separation of Sister Chromatids"
XP_050301359.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_050297994.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050307862.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050309891.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050295526.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5856;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5871	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_050311745.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050298035.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050304929.1	6	MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II"
XP_050301953.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050313739.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_050295165.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-532668;Reactome: R-HSA-174154;Reactome: R-HSA-1169091	"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of DVL";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells"
XP_050308671.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050297238.1	10	Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Receptor Mediated Mitophagy";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation"
XP_050295908.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050299370.1	4	MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688	"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism"
XP_050293342.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex"
XP_050314197.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050306587.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050308933.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Triglyceride biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050296879.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation"
XP_050294497.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050303480.1	6	KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Cysteine and methionine metabolism"
XP_050315048.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050297043.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050316333.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050303327.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050306536.1	4	Reactome: R-HSA-4420097;Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753	"VEGFA-VEGFR2 Pathway";"Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions"
XP_050310645.1	11	MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-7586;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8	"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism"
XP_050301479.1	6	Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183	"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050306368.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050309278.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050296018.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_050297546.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305483.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050298919.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050310023.1	5	KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4	"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation"
XP_050308161.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050315477.1	3	MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050309371.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism"
XP_050308960.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_050306543.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050298730.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724	"Macroautophagy";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription"
XP_050299965.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050295250.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_050306028.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050303409.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_050304960.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050297662.1	14	MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622	"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine betaine degradation I";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Folate transformations I";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Photorespiration ";"Folate polyglutamylation";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)"
XP_050300231.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050304978.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050307864.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050298186.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050301020.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814	"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes"
XP_050295716.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050295901.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_050299102.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050306855.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050312355.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050296030.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_050296916.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050292775.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050292979.1	12	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;MetaCyc: PWY-7221	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis"
XP_050315769.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050301572.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050316363.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050301986.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050311492.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_050293468.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050310354.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050314512.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_050299061.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050296216.1	18	KEGG: 00020+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00010+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;MetaCyc: PWY-5084;MetaCyc: PWY-5046;Reactome: R-HSA-70895;KEGG: 00620+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00380+1.8.1.4;KEGG: 00280+1.8.1.4;KEGG: 00310+1.8.1.4	"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"Lysine catabolism";"Glycine degradation";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Lysine degradation"
XP_050308203.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050298977.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482839;MetaCyc: PWY-6803	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing"
XP_050304434.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050306305.1	7	Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Meiotic synapsis";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_050312443.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050295958.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050299836.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050309910.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_050299011.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050305459.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050298126.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108	"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"Estrogen-dependent gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_050309961.1	11	MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381	"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)"
XP_050294837.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050297599.1	8	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_050297173.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_050296815.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_050296167.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807	"T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling"
XP_050302029.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050303492.1	10	KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Galactose metabolism";"MPS VII - Sly syndrome"
XP_050315903.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300230.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050300197.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050293156.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_050307692.1	7	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans"
XP_050314191.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050294849.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050311251.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_050301426.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050295556.1	21	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7219;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7197;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7224;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_050305773.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_050308655.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050298707.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_050306301.1	7	Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214	"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins"
XP_050309686.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050297430.1	8	Reactome: R-HSA-8941284;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681	"RUNX2 regulates chondrocyte maturation";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions"
XP_050304785.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050302197.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_050310093.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050311633.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050297066.1	4	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_050302861.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_050295560.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_050305039.1	7	KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7185	"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP dephosphorylation I"
XP_050305417.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050303135.1	1	KEGG: 00230+3.6.1.29	"Purine metabolism"
XP_050303601.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050310262.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050295314.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050303094.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050308878.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050307986.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050308621.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_050299889.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050303243.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050308955.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_050309318.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297660.1	14	MetaCyc: PWY-2161;KEGG: 00460+2.1.2.1;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2201;MetaCyc: PWY-3841	"Folate polyglutamylation";"Cyanoamino acid metabolism";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Methane metabolism";"Glycine, serine and threonine metabolism";"Folate transformations I";"Folate transformations II (plants)"
XP_050300860.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_050298921.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050306901.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050309889.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050294864.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050297471.1	12	Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343	"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Stachyose degradation";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen synthesis";"Galactose metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I"
XP_050307709.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050312842.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050304971.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050316320.1	4	MetaCyc: PWY-7887;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581	"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050301889.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_050295975.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050301791.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050311608.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050308918.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_050295066.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050312896.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050294845.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050294277.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050310454.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050298013.1	5	KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_050296684.1	8	MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;Reactome: R-HSA-70635	"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Urea cycle"
XP_050312262.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050311573.1	4	KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050314269.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050300791.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050306132.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway"
XP_050304794.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050302385.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050310607.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050295055.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050300249.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050306149.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050302682.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis"
XP_050293149.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050308201.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050304222.1	6	Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922;MetaCyc: PWY-4981	"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)"
XP_050306620.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_050312187.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050294518.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_050314575.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_050298724.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050297440.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_050312422.1	4	KEGG: 00513+2.4.1.142;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.142	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
XP_050297366.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050295906.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050316407.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050303904.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_050292689.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050300152.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_050306471.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050305983.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050294683.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050297837.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050305564.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050299850.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050315585.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050302321.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050297223.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050309561.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294430.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events"
XP_050305964.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050311964.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310266.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050295741.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_050313224.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050306839.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050300075.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050294799.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050306693.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050313948.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_050294501.1	3	Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21	"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system"
XP_050298661.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050308496.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310554.1	14	MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433	"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)"
XP_050297726.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_050296703.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_050301545.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050309479.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892	"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation"
XP_050296485.1	19	MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-380320;MetaCyc: PWY-7220;Reactome: R-HSA-380270;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_050313790.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050313204.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
XP_050300763.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870	"Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050311144.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226	"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050309801.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_050311123.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050309776.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_050298317.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_050313530.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310254.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050305365.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050315130.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050310173.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050307389.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050312749.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050308971.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050292782.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050296975.1	4	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_050316309.1	4	MetaCyc: PWY-7286;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_050299494.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_050315329.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050307607.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050303674.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050293493.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events"
XP_050293318.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050302149.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050295869.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050303545.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050308672.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050301429.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050312195.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050312865.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050313727.1	4	MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32	"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism"
XP_050301456.1	9	MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18;Reactome: R-HSA-156590	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Glutathione metabolism";"Glutathione conjugation"
XP_050296617.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050299971.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050314864.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050295118.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050297549.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299655.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050297055.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300	"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling"
XP_050302024.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050304317.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis"
XP_050295907.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050301357.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation"
XP_050314714.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_050303028.1	8	Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1	"Glycolysis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050300832.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-165159	"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Macroautophagy";"mTOR signalling"
XP_050297814.1	83	Reactome: R-HSA-1257604;Reactome: R-HSA-8875360;Reactome: R-HSA-2219530;Reactome: R-HSA-6807004;Reactome: R-HSA-1433559;Reactome: R-HSA-9664565;Reactome: R-HSA-912526;Reactome: R-HSA-5655253;Reactome: R-HSA-354194;Reactome: R-HSA-1250196;Reactome: R-HSA-179812;Reactome: R-HSA-167044;Reactome: R-HSA-2179392;Reactome: R-HSA-8853338;Reactome: R-HSA-5654732;Reactome: R-HSA-210993;Reactome: R-HSA-5655291;Reactome: R-HSA-9027284;Reactome: R-HSA-5654689;Reactome: R-HSA-391160;Reactome: R-HSA-109704;Reactome: R-HSA-182971;Reactome: R-HSA-388841;Reactome: R-HSA-2730905;Reactome: R-HSA-5654720;Reactome: R-HSA-5654699;Reactome: R-HSA-5654693;Reactome: R-HSA-5654733;Reactome: R-HSA-2871796;Reactome: R-HSA-389359;Reactome: R-HSA-8856825;Reactome: R-HSA-5654727;Reactome: R-HSA-8983432;Reactome: R-HSA-1433557;Reactome: R-HSA-5654700;Reactome: R-HSA-1295596;Reactome: R-HSA-8853334;Reactome: R-HSA-9028731;Reactome: R-HSA-2424491;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-5654710;Reactome: R-HSA-8875656;Reactome: R-HSA-1839117;Reactome: R-HSA-180336;Reactome: R-HSA-180292;Reactome: R-HSA-8865999;Reactome: R-HSA-9645135;Reactome: R-HSA-5655302;Reactome: R-HSA-2428933;Reactome: R-HSA-6811558;Reactome: R-HSA-9026519;Reactome: R-HSA-1963642;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-8851805;Reactome: R-HSA-186763;Reactome: R-HSA-512988;Reactome: R-HSA-5654726;Reactome: R-HSA-74749;Reactome: R-HSA-9607240;Reactome: R-HSA-9028335;Reactome: R-HSA-8856828;Reactome: R-HSA-74751;Reactome: R-HSA-375165;Reactome: R-HSA-8875555;Reactome: R-HSA-112412;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-9034864;Reactome: R-HSA-5654704;Reactome: R-HSA-5654719;Reactome: R-HSA-1250347;Reactome: R-HSA-8851907;Reactome: R-HSA-1963640;Reactome: R-HSA-983695;Reactome: R-HSA-5663213;Reactome: R-HSA-5654688;Reactome: R-HSA-5654695;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-9634285;Reactome: R-HSA-5654712	"PIP3 activates AKT signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by Aberrant PI3K in Cancer";"Negative regulation of MET activity";"Regulation of KIT signaling";"Signaling by ERBB2 KD Mutants";"Interleukin receptor SHC signaling";"Signaling by FGFR2 in disease";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"SHC1 events in ERBB2 signaling";"GRB2 events in EGFR signaling";"Signalling to RAS";"EGFR Transactivation by Gastrin";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR3 signaling";"Tie2 Signaling";"Signaling by FGFR4 in disease";"Erythropoietin activates RAS";"PI-3K cascade:FGFR1";"Signal regulatory protein family interactions";"PI3K Cascade";"EGFR downregulation";"Costimulation by the CD28 family";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR4";"SHC-mediated cascade:FGFR2";"FRS-mediated FGFR1 signaling";"Negative regulation of FGFR4 signaling";"FCERI mediated MAPK activation";"CD28 dependent Vav1 pathway";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR2 signaling";"Interleukin-15 signaling";"Signaling by SCF-KIT";"FRS-mediated FGFR2 signaling";"Spry regulation of FGF signaling";"Signaling by FGFR3 fusions in cancer";"Activated NTRK2 signals through FRS2 and FRS3";"DAP12 signaling";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"PI-3K cascade:FGFR3";"MET receptor recycling";"Signaling by cytosolic FGFR1 fusion mutants";"SHC1 events in EGFR signaling";"GAB1 signalosome";"MET activates PTPN11";"STAT5 Activation";"Signaling by FGFR1 in disease";"SHC-related events triggered by IGF1R";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activated NTRK2 signals through RAS";"PI3K events in ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET activates RAS signaling";"Downstream signal transduction";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Negative regulation of FGFR1 signaling";"Signal attenuation";"FLT3 Signaling";"Activated NTRK2 signals through PI3K";"Clathrin-mediated endocytosis";"Insulin receptor signalling cascade";"NCAM signaling for neurite out-growth";"MET activates RAP1 and RAC1";"SOS-mediated signalling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR3";"SHC-mediated cascade:FGFR4";"SHC1 events in ERBB4 signaling";"MET activates PI3K/AKT signaling";"GRB2 events in ERBB2 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"RHO GTPases Activate WASPs and WAVEs";"SHC-mediated cascade:FGFR1";"PI-3K cascade:FGFR2";"RET signaling";"Regulation of signaling by CBL";"Constitutive Signaling by Overexpressed ERBB2";"FRS-mediated FGFR4 signaling"
XP_050314001.1	4	Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"PLC beta mediated events";"G-protein activation";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050299649.1	179	Reactome: R-HSA-4641257;Reactome: R-HSA-6783310;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-1253288;Reactome: R-HSA-2559582;Reactome: R-HSA-6782135;Reactome: R-HSA-2672351;Reactome: R-HSA-1799339;Reactome: R-HSA-2173791;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-8849469;Reactome: R-HSA-5362768;Reactome: R-HSA-6782210;Reactome: R-HSA-2173795;Reactome: R-HSA-75815;Reactome: R-HSA-977225;Reactome: R-HSA-5675482;Reactome: R-HSA-5655862;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-2173796;Reactome: R-HSA-5696394;Reactome: R-HSA-209560;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-9013507;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580;Reactome: R-HSA-8866652;Reactome: R-HSA-1236974;Reactome: R-HSA-8875360;Reactome: R-HSA-5675221;Reactome: R-HSA-450321;Reactome: R-HSA-174490;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-6804756;Reactome: R-HSA-3769402;Reactome: R-HSA-5696395;Reactome: R-HSA-175474;Reactome: R-HSA-5357956;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-6791226;Reactome: R-HSA-5205685;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-8951664;Reactome: R-HSA-8948747;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-9613829;Reactome: R-HSA-211733;Reactome: R-HSA-69231;Reactome: R-HSA-168928;Reactome: R-HSA-209543;Reactome: R-HSA-5632684;Reactome: R-HSA-162588;Reactome: R-HSA-69601;Reactome: R-HSA-6781827;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5696400;Reactome: R-HSA-5610783;Reactome: R-HSA-4641263;Reactome: R-HSA-8863795;Reactome: R-HSA-72706;Reactome: R-HSA-110312;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-9604323;Reactome: R-HSA-6781823;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-5696397;Reactome: R-HSA-202424;Reactome: R-HSA-1236382;Reactome: R-HSA-168927;Reactome: R-HSA-6804760;Reactome: R-HSA-5654727;Reactome: R-HSA-1169091;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-2559585;Reactome: R-HSA-9033241;Reactome: R-HSA-8856825;Reactome: R-HSA-5693607;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-937041;Reactome: R-HSA-5357905;Reactome: R-HSA-9637628;Reactome: R-HSA-179409;Reactome: R-HSA-2122947;Reactome: R-HSA-192823;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-110320;Reactome: R-HSA-69541;Reactome: R-HSA-5685942;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9014325;Reactome: R-HSA-5654732;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-975163;Reactome: R-HSA-174113;Reactome: R-HSA-2122948;Reactome: R-HSA-110314;Reactome: R-HSA-6807004;Reactome: R-HSA-5658442;Reactome: R-HSA-72689;Reactome: R-HSA-400253;Reactome: R-HSA-450302;Reactome: R-HSA-201681;Reactome: R-HSA-349425;Reactome: R-HSA-3322077;Reactome: R-HSA-3785653;Reactome: R-HSA-2408557;Reactome: R-HSA-182971;Reactome: R-HSA-8866654;Reactome: R-HSA-2691232;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-168638;Reactome: R-HSA-975144;Reactome: R-HSA-532668;Reactome: R-HSA-5689901;Reactome: R-HSA-205043;Reactome: R-HSA-8854050;Reactome: R-HSA-1358803;Reactome: R-HSA-69481;Reactome: R-HSA-2979096;Reactome: R-HSA-69017;Reactome: R-HSA-937039;Reactome: R-HSA-5689896;Reactome: R-HSA-5656121;Reactome: R-HSA-8939236;Reactome: R-HSA-5689877;Reactome: R-HSA-912631;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-9615710;Reactome: R-HSA-156902;Reactome: R-HSA-8876493;Reactome: R-HSA-8852276;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-72764;Reactome: R-HSA-2565942;Reactome: R-HSA-450408;Reactome: R-HSA-174048;Reactome: R-HSA-9646399;Reactome: R-HSA-3134975;Reactome: R-HSA-975957;Reactome: R-HSA-445989;Reactome: R-HSA-936440;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-1169408;Reactome: R-HSA-901032;Reactome: R-HSA-156827;Reactome: R-HSA-975110	"Degradation of AXIN";"Fanconi Anemia Pathway";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Downregulation of ERBB4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Dual incision in TC-NER";"Stimuli-sensing channels";"SRP-dependent cotranslational protein targeting to membrane";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Ubiquitin-dependent degradation of Cyclin D";"Amyloid fiber formation";"Regulation of necroptotic cell death";"Translesion synthesis by POLK";"Iron uptake and transport";"UCH proteinases";"ABC-family proteins mediated transport";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"DNA Damage Recognition in GG-NER";"NF-kB is activated and signals survival";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"ER-Phagosome pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MAPK pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Membrane binding and targetting of GAG proteins";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Regulation of TP53 Activity through Phosphorylation";"Deactivation of the beta-catenin transactivating complex";"Formation of Incision Complex in GG-NER";"Assembly Of The HIV Virion";"TNFR1-induced NFkappaB signaling pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Pink/Parkin Mediated Mitophagy";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Neddylation";"Regulation of PTEN localization";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Chaperone Mediated Autophagy";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cyclin D associated events in G1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"p75NTR recruits signalling complexes";"Hedgehog 'on' state";"Budding and maturation of HIV virion";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Dual Incision in GG-NER";"Degradation of GLI2 by the proteasome";"Regulation of FZD by ubiquitination";"Downregulation of ERBB2 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translesion synthesis by REV1";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Negative regulation of NOTCH4 signaling";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downstream TCR signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of TP53 Activity through Methylation";"Negative regulation of FGFR2 signaling";"Activation of NF-kappaB in B cells";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"Oncogene Induced Senescence";"Peroxisomal protein import";"Cargo recognition for clathrin-mediated endocytosis";"Processing of DNA double-strand break ends";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"IKK complex recruitment mediated by RIP1";"Regulation of TNFR1 signaling";"Modulation by Mtb of host immune system";"APC-Cdc20 mediated degradation of Nek2A";"NOTCH1 Intracellular Domain Regulates Transcription";"Viral mRNA Translation";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Translesion Synthesis by POLH";"Stabilization of p53";"HDR through Homologous Recombination (HRR)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulation of FGFR3 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"SCF-beta-TrCP mediated degradation of Emi1";"Activated NOTCH1 Transmits Signal to the Nucleus";"Recognition of DNA damage by PCNA-containing replication complex";"Negative regulation of MET activity";"Regulation of RAS by GAPs";"Formation of a pool of free 40S subunits";"Circadian Clock";"activated TAK1 mediates p38 MAPK activation";"TCF dependent signaling in response to WNT";"Autodegradation of the E3 ubiquitin ligase COP1";"Glycogen synthesis";"Myoclonic epilepsy of Lafora";"Selenocysteine synthesis";"EGFR downregulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Metalloprotease DUBs";"NRIF signals cell death from the nucleus";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downregulation of ERBB2:ERBB3 signaling";"G2/M Checkpoints";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"CDK-mediated phosphorylation and removal of Cdc6";"IRAK1 recruits IKK complex";"Ovarian tumor domain proteases";"Translesion synthesis by POLI";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Josephin domain DUBs";"Regulation of signaling by CBL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"Late endosomal microautophagy";"Peptide chain elongation";"InlA-mediated entry of Listeria monocytogenes into host cells";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"Eukaryotic Translation Termination";"Regulation of PLK1 Activity at G2/M Transition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Cyclin B";"Aggrephagy";"Regulation of innate immune responses to cytosolic DNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulators of DDX58/IFIH1 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"ISG15 antiviral mechanism";"ER Quality Control Compartment (ERQC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"
XP_050316330.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050311388.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050301788.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050302732.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050299480.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050314265.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_050310112.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050301551.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050309583.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_050312717.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_050314097.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050304167.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314561.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050294677.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation"
XP_050302588.1	4	Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710	"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy"
XP_050298889.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_050301056.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050300449.1	9	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol"
XP_050296696.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050296593.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_050307745.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050315849.1	6	Reactome: R-HSA-2426168;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_050302617.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050303790.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050296857.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050310237.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050304245.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050298718.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050297831.1	7	KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis"
XP_050302299.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050301816.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-112311;Reactome: R-HSA-422085	"Synthesis of PC";"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050301989.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050310264.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050301757.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_050292804.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050310319.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050307690.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105	"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation"
XP_050308770.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050305367.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050311587.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050292971.1	12	MetaCyc: PWY-6142;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Fructose and mannose metabolism"
XP_050298107.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050297188.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_050307148.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050295775.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050304850.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050298872.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050293788.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050305471.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050315611.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_050302147.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050301955.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050295161.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050293311.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_050297627.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050310560.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_050307035.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050306084.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-5674400	"HSF1-dependent transactivation";"mTOR signalling";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_050299570.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_050312185.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050313111.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050312000.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297703.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_050316312.1	25	Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840;Reactome: R-HSA-380270;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813	"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids"
XP_050310243.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050303911.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050307771.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050310258.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300850.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_050315761.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050305736.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050298823.1	27	Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885	"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins"
XP_050302020.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050305782.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-5696395	"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER"
XP_050315426.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050306889.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050312866.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_050315215.1	8	Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5628897	"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes"
XP_050308231.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050297364.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050293140.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050307326.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"UCH proteinases";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling"
XP_050311366.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050308229.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050312090.1	12	MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4	"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Transport and synthesis of PAPS";"Sulfate activation for sulfonation";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Purine metabolism"
XP_050298876.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases"
XP_050301164.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050295918.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_050313572.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_050295676.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-182218	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Nef Mediated CD8 Down-regulation"
XP_050300224.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050303183.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-8950505	"Mitochondrial protein import";"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050295383.1	5	MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_050308094.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050307945.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_050304933.1	14	MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-7254;MetaCyc: PWY-7279;Reactome: R-HSA-71403	"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Citric acid cycle (TCA cycle)"
XP_050293862.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050296700.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050303921.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050293979.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050312695.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050305785.1	4	Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374	"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_050304976.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050296224.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050299090.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050301708.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs"
XP_050312202.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050303741.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050295377.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050314369.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050301415.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593	"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity"
XP_050307767.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050303329.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050311372.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050311407.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050299323.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296510.1	52	Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-76071;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-5617472;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation"
XP_050303651.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305985.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050300973.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050299311.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050311618.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050312353.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-6804760;Reactome: R-HSA-191859	"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation";"snRNP Assembly"
XP_050296325.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_050306862.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_050296569.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050296582.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050302486.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050303635.1	6	Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52;MetaCyc: PWY-8010	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism";"Vitamin B6 metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)"
XP_050312511.1	3	Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050296539.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing"
XP_050301428.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050303650.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050299321.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050314823.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050312386.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050304219.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_050310351.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling"
XP_050313742.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050306898.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_050297875.1	9	KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I"
XP_050308391.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050311978.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310517.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050301818.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_050314567.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050300604.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050311717.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295	"Neutrophil degranulation";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation"
XP_050316326.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050300778.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_050314541.1	13	Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-4086398;Reactome: R-HSA-112043	"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Ca2+ pathway";"PLC beta mediated events"
XP_050296471.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304760.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050309466.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298852.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050302028.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050301964.1	2	Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis";"Gluconeogenesis"
XP_050305171.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_050307798.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050294669.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050296527.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050303572.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296987.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape"
XP_050292840.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050305101.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_050294810.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050294716.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050302360.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050307114.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050306379.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050303587.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_050316264.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050306468.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050297045.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_050294011.1	6	KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807	"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_050295477.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-167242	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050312693.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050310282.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_050313549.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050313619.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-389977	"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Kinesins";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway"
XP_050304798.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_050305416.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050296856.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050297847.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050303740.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050306315.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050302684.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050299652.1	13	KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101	"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"CS/DS degradation"
XP_050311684.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050302362.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050316323.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050304072.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_050312054.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_050305709.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050312027.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050308649.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050311294.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_050308965.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050301221.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050313535.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307796.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050302061.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050310676.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050307775.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050313169.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_050307208.1	5	MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695;KEGG: 00030+4.1.2.4	"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation";"Pentose phosphate pathway"
XP_050311103.1	12	MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_050300972.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_050296576.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050313081.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_050297767.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050310779.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_050300353.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_050306605.1	57	Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902	"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity"
XP_050293050.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050302996.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050293148.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050310379.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050296120.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295176.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050295137.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167242	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050308319.1	26	Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-4615885;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-69205;Reactome: R-HSA-174417;Reactome: R-HSA-5655862;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-110320;Reactome: R-HSA-8866654;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-1362277;Reactome: R-HSA-5358565;Reactome: R-HSA-6804114	"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"SUMOylation of DNA replication proteins";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"G1/S-Specific Transcription";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLK";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Translesion Synthesis by POLH";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_050304429.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_050309596.1	10	Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897	"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes"
XP_050308146.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase"
XP_050315148.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050310610.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_050314771.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050304936.1	10	MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-6372;Reactome: R-HSA-1855191;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of IPs in the nucleus";"Synthesis of pyrophosphates in the cytosol"
XP_050303656.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_050309983.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050300046.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050297496.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050313683.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050311788.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050296278.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050312675.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_050304881.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050300898.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression"
XP_050303984.1	4	Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-198693	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus"
XP_050295736.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050297354.1	26	Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050303502.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050292922.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862	"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"Translesion synthesis by POLK"
XP_050293525.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050309270.1	24	Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-381676;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-9009391	"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling"
XP_050314105.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050299648.1	179	Reactome: R-HSA-2173796;Reactome: R-HSA-382556;Reactome: R-HSA-5696394;Reactome: R-HSA-209560;Reactome: R-HSA-917937;Reactome: R-HSA-977225;Reactome: R-HSA-5675482;Reactome: R-HSA-75815;Reactome: R-HSA-5655862;Reactome: R-HSA-5689603;Reactome: R-HSA-2173795;Reactome: R-HSA-5362768;Reactome: R-HSA-6782210;Reactome: R-HSA-2173791;Reactome: R-HSA-1799339;Reactome: R-HSA-8849469;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-2672351;Reactome: R-HSA-6782135;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-1253288;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-6783310;Reactome: R-HSA-175474;Reactome: R-HSA-5357956;Reactome: R-HSA-3769402;Reactome: R-HSA-6804756;Reactome: R-HSA-5696395;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-450321;Reactome: R-HSA-174490;Reactome: R-HSA-8875360;Reactome: R-HSA-5675221;Reactome: R-HSA-2559580;Reactome: R-HSA-9013507;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-1236974;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-209543;Reactome: R-HSA-162588;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-69231;Reactome: R-HSA-168928;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-9613829;Reactome: R-HSA-8948747;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-6791226;Reactome: R-HSA-5607761;Reactome: R-HSA-5205685;Reactome: R-HSA-2894862;Reactome: R-HSA-1236382;Reactome: R-HSA-5696397;Reactome: R-HSA-202424;Reactome: R-HSA-168927;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-4641258;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-6781823;Reactome: R-HSA-5654726;Reactome: R-HSA-110312;Reactome: R-HSA-6804757;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8863795;Reactome: R-HSA-72706;Reactome: R-HSA-5610783;Reactome: R-HSA-5696400;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-4641263;Reactome: R-HSA-6781827;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-110320;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-192823;Reactome: R-HSA-5357905;Reactome: R-HSA-9637628;Reactome: R-HSA-937041;Reactome: R-HSA-2122947;Reactome: R-HSA-179409;Reactome: R-HSA-5684264;Reactome: R-HSA-9033241;Reactome: R-HSA-8856825;Reactome: R-HSA-2559585;Reactome: R-HSA-2871837;Reactome: R-HSA-5693607;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-1169091;Reactome: R-HSA-1295596;Reactome: R-HSA-9636383;Reactome: R-HSA-5654727;Reactome: R-HSA-6804760;Reactome: R-HSA-8866654;Reactome: R-HSA-2691232;Reactome: R-HSA-9633012;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-3785653;Reactome: R-HSA-349425;Reactome: R-HSA-201681;Reactome: R-HSA-3322077;Reactome: R-HSA-400253;Reactome: R-HSA-450302;Reactome: R-HSA-2122948;Reactome: R-HSA-110314;Reactome: R-HSA-174113;Reactome: R-HSA-72689;Reactome: R-HSA-5658442;Reactome: R-HSA-6807004;Reactome: R-HSA-174084;Reactome: R-HSA-9014325;Reactome: R-HSA-5668541;Reactome: R-HSA-5654732;Reactome: R-HSA-2467813;Reactome: R-HSA-975163;Reactome: R-HSA-5685942;Reactome: R-HSA-69541;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-68827;Reactome: R-HSA-156902;Reactome: R-HSA-9615710;Reactome: R-HSA-174184;Reactome: R-HSA-5689877;Reactome: R-HSA-912631;Reactome: R-HSA-5656121;Reactome: R-HSA-8939236;Reactome: R-HSA-5689896;Reactome: R-HSA-2979096;Reactome: R-HSA-1358803;Reactome: R-HSA-69481;Reactome: R-HSA-937039;Reactome: R-HSA-69017;Reactome: R-HSA-5689901;Reactome: R-HSA-532668;Reactome: R-HSA-205043;Reactome: R-HSA-8854050;Reactome: R-HSA-975956;Reactome: R-HSA-168638;Reactome: R-HSA-975144;Reactome: R-HSA-975110;Reactome: R-HSA-156827;Reactome: R-HSA-68949;Reactome: R-HSA-901032;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-3134975;Reactome: R-HSA-2644606;Reactome: R-HSA-445989;Reactome: R-HSA-936440;Reactome: R-HSA-174048;Reactome: R-HSA-450408;Reactome: R-HSA-9646399;Reactome: R-HSA-2565942;Reactome: R-HSA-8852276;Reactome: R-HSA-8876493;Reactome: R-HSA-72764;Reactome: R-HSA-937042;Reactome: R-HSA-9645460	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"ABC-family proteins mediated transport";"DNA Damage Recognition in GG-NER";"NF-kB is activated and signals survival";"Iron uptake and transport";"Amyloid fiber formation";"Regulation of necroptotic cell death";"Ubiquitin-dependent degradation of Cyclin D";"Translesion synthesis by POLK";"UCH proteinases";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SRP-dependent cotranslational protein targeting to membrane";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"Stimuli-sensing channels";"Dual incision in TC-NER";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Fanconi Anemia Pathway";"Assembly Of The HIV Virion";"TNFR1-induced NFkappaB signaling pathway";"Deactivation of the beta-catenin transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of Incision Complex in GG-NER";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Membrane binding and targetting of GAG proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MAPK pathway";"Oxidative Stress Induced Senescence";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ER-Phagosome pathway";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"p75NTR recruits signalling complexes";"Budding and maturation of HIV virion";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cyclin D associated events in G1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Chaperone Mediated Autophagy";"Regulation of PTEN localization";"Neddylation";"MAPK6/MAPK4 signaling";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Dectin-1 mediated noncanonical NF-kB signaling";"Pink/Parkin Mediated Mitophagy";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downstream TCR signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Degradation of DVL";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of FGFR1 signaling";"Translesion synthesis by REV1";"Regulation of TP53 Degradation";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Downregulation of ERBB2 signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Degradation of GLI2 by the proteasome";"Dual Incision in GG-NER";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Regulation of FZD by ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Translesion Synthesis by POLH";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Viral mRNA Translation";"Regulation of TNFR1 signaling";"Modulation by Mtb of host immune system";"IKK complex recruitment mediated by RIP1";"NOTCH1 Intracellular Domain Regulates Transcription";"APC-Cdc20 mediated degradation of Nek2A";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Peroxisomal protein import";"Cargo recognition for clathrin-mediated endocytosis";"Oncogene Induced Senescence";"FCERI mediated NF-kB activation";"Processing of DNA double-strand break ends";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"Activation of NF-kappaB in B cells";"Spry regulation of FGF signaling";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of FGFR2 signaling";"Regulation of TP53 Activity through Methylation";"E3 ubiquitin ligases ubiquitinate target proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"EGFR downregulation";"Selenocysteine synthesis";"Myoclonic epilepsy of Lafora";"Autodegradation of the E3 ubiquitin ligase COP1";"TCF dependent signaling in response to WNT";"Glycogen synthesis";"Circadian Clock";"activated TAK1 mediates p38 MAPK activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Recognition of DNA damage by PCNA-containing replication complex";"SCF-beta-TrCP mediated degradation of Emi1";"Formation of a pool of free 40S subunits";"Regulation of RAS by GAPs";"Negative regulation of MET activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of FGFR3 signaling";"Separation of Sister Chromatids";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"HDR through Homologous Recombination (HRR)";"Stabilization of p53";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDT1 association with the CDC6:ORC:origin complex";"Peptide chain elongation";"Late endosomal microautophagy";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Josephin domain DUBs";"Regulation of signaling by CBL";"Translesion synthesis by POLI";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ovarian tumor domain proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Downregulation of ERBB2:ERBB3 signaling";"G2/M Checkpoints";"IRAK1 recruits IKK complex";"CDK-mediated phosphorylation and removal of Cdc6";"Metalloprotease DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"NRIF signals cell death from the nucleus";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"NOD1/2 Signaling Pathway";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Orc1 removal from chromatin";"ER Quality Control Compartment (ERQC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of innate immune responses to cytosolic DNA";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Negative regulators of DDX58/IFIH1 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Aggrephagy";"Regulation of PLK1 Activity at G2/M Transition";"The role of GTSE1 in G2/M progression after G2 checkpoint";"InlA-mediated entry of Listeria monocytogenes into host cells";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway"
XP_050292730.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803	"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing"
XP_050300725.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050302995.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_050312059.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_050311114.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050305851.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684	"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism"
XP_050294504.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_050308910.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050310537.1	4	Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_050313577.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_050314435.1	6	KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780	"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism"
XP_050295535.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_050302527.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050315182.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050311309.1	12	KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;Reactome: R-HSA-196780;MetaCyc: PWY-6613;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;MetaCyc: PWY-6121	"One carbon pool by folate";"Purine metabolism";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_050296119.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299910.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide"
XP_050292794.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050305114.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_050302416.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050312509.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_050305740.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050300298.1	6	Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6731	"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation V";"Starch degradation III"
XP_050308095.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050296040.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050299479.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_050313080.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050295464.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050299985.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050314003.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism"
XP_050299716.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050303932.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050294918.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_050308520.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050315854.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050313143.1	11	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04714+2.7.11.1;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"FOXO-mediated transcription of cell death genes";"Thermogenesis";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection"
XP_050312426.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_050312147.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_050303396.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050311560.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050310961.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050296054.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300896.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050312436.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_050298915.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050303483.1	6	KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism"
XP_050295620.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050315464.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050308463.1	5	MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_050297111.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378	"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling"
XP_050296038.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050313924.1	20	MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-6920;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574	"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"6-gingerol analog biosynthesis (engineered)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II"
XP_050303622.1	10	KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11	"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis"
XP_050303146.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050306455.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323	"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"UCH proteinases";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling"
XP_050313109.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050308180.1	30	Reactome: R-HSA-202424;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-2644606;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-2894862	"Downstream TCR signaling";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Prolactin receptor signaling";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050306133.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050301661.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Cleavage of the damaged pyrimidine";"Meiotic synapsis";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_050313249.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050304499.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050310538.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050306354.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050315910.1	4	Reactome: R-HSA-373760;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-447043	"L1CAM interactions";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Neurofascin interactions"
XP_050295905.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050294140.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050309612.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050292854.1	13	Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;Reactome: R-HSA-202433;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Generation of second messenger molecules";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050301259.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050303689.1	13	MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-7384;Reactome: R-HSA-71403	"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)"
XP_050314763.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949	"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin"
XP_050297555.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_050293705.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism"
XP_050300406.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_050314241.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_050312415.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050297929.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine"
XP_050314845.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_050294516.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050300737.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050311045.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_050301267.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050298334.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_050299594.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050301698.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050305683.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_050293038.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050313278.1	5	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050299289.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_050314247.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050304253.1	6	Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430	"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling"
XP_050310760.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050308884.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050312727.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050296095.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304026.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050294836.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050300123.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050299613.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050303033.1	8	KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Galactose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050307623.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_050307939.1	29	Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-69541;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;KEGG: 04714+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Human papillomavirus infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Stabilization of p53";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PI3K-Akt signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Thermogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050294513.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050294004.1	10	KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11	"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis"
XP_050309174.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050303600.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_050315675.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050299714.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050302568.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135	"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation"
XP_050316331.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050297069.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050304040.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050305991.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_050307670.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050306937.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050308643.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050299096.1	15	Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174178	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_050294846.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050297365.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050294436.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events"
XP_050303272.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050308343.1	5	KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33	"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis"
XP_050306093.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050308156.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050312160.1	52	Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-167246;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-203927;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-112382	"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated elongation of the HIV-1 transcript";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex"
XP_050313764.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050312704.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050293957.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050313343.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050296331.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_050314107.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050311678.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050312219.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050297216.1	4	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I";"Glycerolipid metabolism"
XP_050310704.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050300666.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050311423.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050299397.1	2	Reactome: R-HSA-5693554;Reactome: R-HSA-2564830	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly"
XP_050302475.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050295293.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974	"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway"
XP_050307608.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050302620.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050316357.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293955.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167200	"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_050312258.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050313250.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_050313290.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050311789.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050304638.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050298934.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050298924.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050294995.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050314010.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_050293415.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050310207.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050298007.1	17	Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-1834949;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548	"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic sensors of pathogen-associated DNA";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks"
XP_050302027.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050300545.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050294439.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050295508.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050298255.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050303013.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_050307552.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050295621.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050307219.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050307211.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050308363.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_050309169.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110312	"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Polymerase switching";"Translesion synthesis by REV1"
XP_050304571.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050295335.1	3	Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism";"Purine metabolism"
XP_050315481.1	3	KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_050315126.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_050305158.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050308664.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050298745.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050304443.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050307452.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050314705.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050304379.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_050308071.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_050302127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050310007.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050311966.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310453.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050304830.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662	"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism"
XP_050306372.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_050303255.1	19	Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-8964616;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5627123	"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"G beta:gamma signalling through CDC42";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate PAKs"
XP_050312198.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050295957.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050312155.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050302025.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050315132.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_050311673.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050308673.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050308930.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050314361.1	3	MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456	"Retinol biosynthesis";"Glycerolipid metabolism";"Digestion of dietary lipid"
XP_050302704.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_050294583.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_050292765.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050307037.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050302619.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050310172.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050302249.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050310876.1	19	MetaCyc: PWY-735;MetaCyc: PWY-7338;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-6837	"Jasmonic acid biosynthesis";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)"
XP_050309284.1	5	MetaCyc: PWY-7204;Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism"
XP_050301247.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_050302562.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_050297252.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306939.1	3	MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0	"Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III"
XP_050302312.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050298125.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050313871.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050307591.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050310330.1	6	Reactome: R-HSA-5673001;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700	"RAF/MAP kinase cascade";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling"
XP_050300798.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Rho GTPase cycle";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050305678.1	2	Reactome: R-HSA-3322077;Reactome: R-HSA-3785653	"Glycogen synthesis";"Myoclonic epilepsy of Lafora"
XP_050314825.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050305987.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050302390.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050314499.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_050300118.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050299271.1	31	MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-6799;MetaCyc: PWY-5142;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5971;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWYG-321;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-4381;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8012;MetaCyc: PWY-7723	"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mupirocin biosynthesis";"Bacterial bioluminescence"
XP_050305393.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050293016.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050301547.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_050306983.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050313454.1	23	Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-428930	"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor"
XP_050295630.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050301232.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050303239.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050295529.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050294825.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211	"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling"
XP_050312365.1	2	MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism"
XP_050308101.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050302675.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_050301315.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050306289.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050308228.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_050310309.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050300993.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_050311976.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312197.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050298216.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050304298.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_050312005.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303388.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050304970.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297624.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050300920.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050293150.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050312288.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway"
XP_050296177.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685	"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy"
XP_050300987.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_050299582.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050315573.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295	"COPII-mediated vesicle transport";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation"
XP_050311389.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050294938.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050316144.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050297464.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_050303123.1	1	Reactome: R-HSA-8950505	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_050316391.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
XP_050298173.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050301402.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050314546.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_050310541.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_050305645.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050293024.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050303076.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050304810.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050312205.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050310295.1	56	Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236	"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"UCH proteinases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_050293403.1	5	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR"
XP_050304935.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_050299317.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6798695	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation"
XP_050315440.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050301620.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_050297277.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050308115.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050293579.1	13	Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101	"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"CS/DS degradation"
XP_050308871.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050308183.1	30	Reactome: R-HSA-187577;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-202424	"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Circadian Clock";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling"
XP_050307772.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050298600.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050296540.1	4	Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050303783.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050311143.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050303260.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050295798.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_050295853.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_050297792.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949	"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hedgehog 'on' state";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin"
XP_050299408.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050310068.1	5	MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4	"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism"
XP_050299471.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_050305798.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050302917.1	3	Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"Rap1 signalling";"cGMP effects";"Ca2+ pathway"
XP_050309206.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050294015.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050293716.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_050302204.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308825.1	33	Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531	"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"RHO GTPases Activate Formins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus"
XP_050299472.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050306175.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050302366.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050298387.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050310959.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050294105.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_050307373.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050295249.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_050313390.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050316236.1	11	MetaCyc: PWY-5123;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-7524;MetaCyc: PWY-922;MetaCyc: PWY-6859;Reactome: R-HSA-191273;MetaCyc: PWY-7102;MetaCyc: PWY-7391;MetaCyc: PWY-6174	"Trans, trans-farnesyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Cholesterol biosynthesis";"Bisabolene biosynthesis (engineered)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)"
XP_050293940.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_050311037.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_050295759.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050312738.1	3	MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE"
XP_050293246.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050293883.1	7	MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686	"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I"
XP_050303036.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050310987.1	42	MetaCyc: PWY-7654;MetaCyc: PWY-7778;MetaCyc: PWY-6583;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7007;MetaCyc: PWY-6945;KEGG: 00640+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7656;MetaCyc: PWY-7401;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-6435;MetaCyc: PWY-1361;MetaCyc: PWY-6946;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-5136;MetaCyc: PWY-6944;MetaCyc: PWY-5109;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00623+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00930+4.2.1.17+1.1.1.35	"(8E,10E)-dodeca-8,10-dienol biosynthesis";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Aminobenzoate degradation";"Fatty acid salvage";"Fatty acid degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Phenylalanine metabolism";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"Androstenedione degradation";"Fermentation to 2-methylbutanoate";"Lysine degradation";"Geraniol degradation";"Limonene and pinene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Tryptophan metabolism";"Benzoate degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Toluene degradation";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Caprolactam degradation"
XP_050293036.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050309832.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050293344.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050310382.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_050295350.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_050296575.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050293418.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050309235.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6453	"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis"
XP_050310606.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_050310916.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050298508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050313174.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050301440.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050310917.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050309550.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"MHC class II antigen presentation";"Intraflagellar transport"
XP_050299781.1	6	KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25	"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism"
XP_050293854.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050304752.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_050302441.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050309334.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_050306114.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050293677.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050294640.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050304224.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050296029.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050313512.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050298642.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050313608.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050305998.1	6	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050315553.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050308253.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_050312189.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050309198.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050299597.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_050298071.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050293543.1	6	KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23	"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism"
XP_050300546.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050304629.1	7	Reactome: R-HSA-171319;Reactome: R-HSA-606279;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-5696394	"Telomere Extension By Telomerase";"Deposition of new CENPA-containing nucleosomes at the centromere";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER"
XP_050306257.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050293850.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050305679.1	2	Reactome: R-HSA-3785653;Reactome: R-HSA-3322077	"Myoclonic epilepsy of Lafora";"Glycogen synthesis"
XP_050314145.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050313760.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050314866.1	1	Reactome: R-HSA-200425	"Carnitine metabolism"
XP_050303971.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050308324.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050296449.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_050308358.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050304413.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050311308.1	12	KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;MetaCyc: PWY-6121;Reactome: R-HSA-196780;MetaCyc: PWY-6613;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.2	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Biotin transport and metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"One carbon pool by folate"
XP_050316356.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294933.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110329	"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged pyrimidine"
XP_050294141.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050309921.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050311969.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304577.1	10	MetaCyc: PWY-6535;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;KEGG: 00410+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;Reactome: R-HSA-916853;MetaCyc: PWY-6536	"4-aminobutanoate degradation I";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"beta-Alanine metabolism";"Propanoate metabolism";"L-glutamate degradation IV";"Butanoate metabolism";"4-aminobutanoate degradation V";"Degradation of GABA";"4-aminobutanoate degradation III"
XP_050298116.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_050295846.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050295409.1	11	MetaCyc: PWY-7560;MetaCyc: PWY-6383;KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6859;MetaCyc: PWY-7524	"Methylerythritol phosphate pathway II";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Mevalonate pathway III (archaea)"
XP_050314080.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050298241.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050309529.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050307943.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_050303915.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_050305691.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050298174.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050311401.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050303223.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism"
XP_050301720.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050293270.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_050313223.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050297044.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050298865.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050299306.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050311877.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050299801.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050302381.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_050296583.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050304410.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-180746	"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein"
XP_050294873.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_050300402.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_050314019.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_050308954.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_050300228.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050299406.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050307727.1	3	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions"
XP_050293871.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050302026.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_050302919.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
XP_050295616.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050310759.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050301613.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_050313560.1	6	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_050310010.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050299407.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050295091.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050309486.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_050314367.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_050295867.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050304431.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_050313339.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs"
XP_050303688.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050301032.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2465910;KEGG: 05165+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"MASTL Facilitates Mitotic Progression";"Human papillomavirus infection"
XP_050305698.1	3	MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_050310946.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050299292.1	30	Reactome: R-HSA-8948751;Reactome: R-HSA-198323;Reactome: R-HSA-69656;Reactome: R-HSA-211163;Reactome: R-HSA-198693;Reactome: R-HSA-8876198;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-5218920;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-111447;Reactome: R-HSA-69202;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 05165+2.7.11.1;Reactome: R-HSA-199418;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-8941332;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-6804758;Reactome: R-HSA-389513;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Regulation of PTEN stability and activity";"AKT phosphorylates targets in the cytosol";"Cyclin A:Cdk2-associated events at S phase entry";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the nucleus";"RAB GEFs exchange GTP for GDP on RABs";"Thermogenesis";"Regulation of localization of FOXO transcription factors";"VEGFR2 mediated vascular permeability";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Relaxin signaling pathway";"Regulation of TP53 Activity through Association with Co-factors";"Human papillomavirus infection";"Negative regulation of the PI3K/AKT network";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"RUNX2 regulates genes involved in cell migration";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Acetylation";"CTLA4 inhibitory signaling";"PI3K-Akt signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_050298755.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050310799.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050295989.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_050301730.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050307298.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050308181.1	30	Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-1170546;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-2894862;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-69231;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607	"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Prolactin receptor signaling";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"Cyclin D associated events in G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"
XP_050305829.1	19	KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-8086;Reactome: R-HSA-71403;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37	"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Methane metabolism";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms"
XP_050298715.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050294074.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_050316324.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050294415.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050311014.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050311971.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314110.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297465.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050307310.1	10	KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695	"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Glycosaminoglycan degradation";"Neutrophil degranulation"
XP_050302570.1	13	Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1	"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection"
XP_050305476.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050310432.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050316338.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050296621.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050302573.1	15	Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700	"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050309915.1	4	Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_050307732.1	4	Reactome: R-HSA-8849175;MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493	"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2"
XP_050301275.1	29	Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-6783310;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-3108214;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5696395;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320	"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Fanconi Anemia Pathway";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HSF1 activation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH"
XP_050299697.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape"
XP_050310296.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974	"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"UCH proteinases";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"ER-Phagosome pathway"
XP_050314074.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_050314928.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050304163.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_050295454.1	8	Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1	"Surfactant metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine metabolism";"Purine deoxyribonucleosides degradation II"
XP_050300774.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_050296535.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_050294473.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050302273.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_050295829.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050309117.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_050293060.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050304503.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050299193.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_050311741.1	34	Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-69202;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-69231;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-69273;Reactome: R-HSA-76042	"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_050311136.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050298804.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5674135	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"MAP2K and MAPK activation"
XP_050315094.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2"
XP_050295234.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_050310521.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis"
XP_050295993.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_050299469.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050299884.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_050314199.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050299218.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)"
XP_050312257.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050306104.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52	"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_050293153.1	7	Reactome: R-HSA-375165;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"NCAM signaling for neurite out-growth";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Nephrin family interactions";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_050308626.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050305320.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050296114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307587.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_050314201.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050307032.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827	"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050315925.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1368082	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression"
XP_050300699.1	8	KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-5394;MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581	"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"Folate biosynthesis";"(S)-reticuline biosynthesis I"
XP_050311520.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050308875.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_050299410.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050311967.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311125.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050302491.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050314762.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050293064.1	3	Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17	"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis"
XP_050308555.1	5	KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981	"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)"
XP_050294841.1	11	Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_050295461.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050314190.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_050304162.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050303874.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_050297510.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050298272.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050312178.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050296660.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_050295590.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050306895.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050295021.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050313839.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_050301533.1	10	MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559	"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway"
XP_050297871.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_050312836.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_050295304.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050306001.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling"
XP_050296099.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307434.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050315186.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050304027.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_050308670.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050308528.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297271.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_050304273.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_050313245.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050293938.1	3	Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627	"O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_050293414.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_050316168.1	57	Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174154	"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of DVL";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin"
XP_050313093.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050296957.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050299324.1	2	KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26	"Galactose metabolism";"Starch and sucrose metabolism"
XP_050296442.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_050296123.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308967.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_050307195.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050302803.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050307648.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_050312228.1	17	MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-7179;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-4202	"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Adenine and adenosine salvage V";"Purine metabolism";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)"
XP_050298224.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050310206.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050299808.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050296460.1	2	Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24	"MAPK6/MAPK4 signaling";"mTOR signaling pathway"
XP_050295920.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050309563.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_050307824.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050313725.1	5	MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891	"Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)"
XP_050296199.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050294084.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050304749.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050293347.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050308876.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050306764.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050294016.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307661.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-6785807	"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling"
XP_050300403.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_050297514.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050300921.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050296414.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-6824	"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis"
XP_050314799.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"PKA activation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_050294506.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050311352.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050310947.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050297692.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050303541.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_050296138.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303000.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050304867.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_050313144.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050295777.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050303838.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_050305156.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050300731.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_050302319.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_050311101.1	12	MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism"
XP_050306593.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050297841.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050300398.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_050304296.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_050295072.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_050314380.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050304056.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050294844.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_050306120.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050296411.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_050313207.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050296270.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050295830.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050310008.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050296112.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304642.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_050315766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050314437.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050311252.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305522.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050301001.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;Reactome: R-HSA-975634	"Urate conversion to allantoin III";"Amyloid fiber formation";"Retinoid cycle disease events";"Purine metabolism";"Neutrophil degranulation";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport"
XP_050314325.1	7	Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-8856828	"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Clathrin-mediated endocytosis"
XP_050301122.1	7	KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183	"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Phytate degradation I";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050296525.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050298505.1	10	Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_050315991.1	11	MetaCyc: PWY-6964;MetaCyc: PWY-6549;Reactome: R-HSA-210455;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2	"Ammonia assimilation cycle II";"L-glutamine biosynthesis III";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Arginine biosynthesis"
XP_050297470.1	12	Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00052+2.7.7.9	"Glycogen synthesis";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Galactose metabolism"
XP_050293645.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050305359.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050298314.1	11	Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1	"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"IRF3-mediated induction of type I IFN";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human papillomavirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection"
XP_050314266.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_050308326.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050303488.1	6	KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050308746.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes"
XP_050294889.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050306294.1	15	Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases"
XP_050299723.1	8	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex"
XP_050310817.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128	"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Orc1 removal from chromatin";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling"
XP_050301559.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050306105.1	13	MetaCyc: PWY-7883;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52	"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation"
XP_050312157.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050300781.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_050299272.1	31	Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-4381;MetaCyc: PWY-5147;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-7723;MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-7858;MetaCyc: PWY-7663;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;Reactome: R-HSA-75105;MetaCyc: PWYG-321;MetaCyc: PWY-8049;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41	"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"(5Z)-dodecenoate biosynthesis II";"Gondoate biosynthesis (anaerobic)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acyl-CoA biosynthesis";"";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"Biotin metabolism"
XP_050300225.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050302608.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050306811.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_050302068.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050293483.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050301165.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050314797.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163615	"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation"
XP_050309892.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050300639.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305398.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050294877.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050313803.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050316090.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050302470.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_050313511.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050305707.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050305469.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050311387.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050303386.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050298896.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_050308659.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_050306598.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation"
XP_050295196.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050308574.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558	"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_050312741.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_050300937.1	3	Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517	"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane"
XP_050307848.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050307218.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050313648.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_050308921.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_050311113.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050299979.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050299126.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050293492.1	6	Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_050300411.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050299848.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050310270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050314147.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050304928.1	6	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism"
XP_050304562.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-975155;Reactome: R-HSA-5602498;Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-5603037	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR2/4)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR5)"
XP_050303974.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050293902.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_050297865.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050311988.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050294009.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685	"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy"
XP_050306599.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050295330.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050297367.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050306986.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050314895.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050294114.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_050297625.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050297153.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-1268020	"Respiratory electron transport";"Complex I biogenesis";"Mitochondrial protein import"
XP_050303256.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_050293022.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_050314613.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_050293238.1	17	MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37	"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methane metabolism";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)"
XP_050298905.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_050294147.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050314992.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_050303694.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_050314680.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_050301524.1	10	MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2	"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism"
XP_050310742.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050297554.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306094.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_050315123.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_050302172.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050302688.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050297675.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050309916.1	4	Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963	"Pyrimidine catabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I"
XP_050307722.1	58	Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-211733	"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of DVL";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation"
XP_050301921.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050308912.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050316336.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050315832.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050308648.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050294346.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_050315369.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_050298285.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_050295468.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050312379.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050315492.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_050310443.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050305568.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050294502.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_050292997.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-167290	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation"
XP_050292893.1	14	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Intraflagellar transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Macroautophagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050299128.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050306461.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050316300.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320	"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH"
XP_050309765.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-5250924	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"B-WICH complex positively regulates rRNA expression"
XP_050315682.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_050298961.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050309642.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_050306440.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050304349.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050301211.1	3	KEGG: 00643+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2	"Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism"
XP_050292969.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_050314581.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_050314450.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_050293730.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_050313800.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050314016.1	1	Reactome: R-HSA-379716	"Cytosolic tRNA aminoacylation"
XP_050294527.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050312170.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050295092.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050299845.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050308411.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050293431.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050315765.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050313964.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_050297679.1	13	MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842	"Gliotoxin biosynthesis";"Glutathione metabolism";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II"
XP_050309143.1	19	KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;Reactome: R-HSA-70263;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-8086;Reactome: R-HSA-71403;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115	"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Methylaspartate cycle";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type"
XP_050303127.1	6	MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-7356	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine salvage IV (yeast)"
XP_050305392.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050295089.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050311875.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_050306155.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase"
XP_050302784.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050293374.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050297697.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050307854.1	4	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_050313486.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050312847.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050307839.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050299832.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050312934.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050309338.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050308138.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050296108.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310001.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208	"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling"
XP_050307833.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050307402.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_050312368.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050308393.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_050297601.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050299779.1	6	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism"
XP_050296146.1	7	KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084	"Lysine degradation";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_050303280.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"Photosynthesis"
XP_050296577.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_050314382.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050315622.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-141430	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_050295273.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_050307739.1	11	Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-174437	"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand"
XP_050316258.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050303912.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050313159.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_050293621.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050293382.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_050312357.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050297213.1	11	Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167290	"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation"
XP_050294507.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_050304174.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050311454.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_050310558.1	11	KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2	"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism"
XP_050295148.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050304337.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_050309911.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050308232.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050300838.1	17	Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-174417;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-174437	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand"
XP_050296098.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310908.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_050312933.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050299182.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050312734.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050301027.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"snRNP Assembly";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050297016.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050304822.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050302363.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050314805.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_050305567.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050305621.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)"
XP_050315095.1	14	Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700	"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_050315276.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050313751.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050297106.1	5	KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;MetaCyc: PWY-7383	"Pyruvate metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_050309699.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050298332.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050299752.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050314322.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation"
XP_050308663.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050309560.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050308631.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050303853.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050304173.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050304107.1	3	KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248;MetaCyc: PWY-7246	"Pentose and glucuronate interconversions";"Pectin degradation II";"Pectin degradation I"
XP_050314748.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_050299958.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_050311986.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050293518.1	6	MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms"
XP_050302410.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050313352.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050310479.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050293007.1	12	KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-442982;Reactome: R-HSA-399719	"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors"
XP_050297631.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050307382.1	6	Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism"
XP_050304229.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling"
XP_050306383.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_050310216.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050311396.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050305979.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050306899.1	14	Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-69091	"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Polymerase switching"
XP_050315136.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_050301920.1	5	Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896;MetaCyc: PWY-7782;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import"
XP_050308306.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_050310388.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism"
XP_050314060.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050312404.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050302587.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9613829	"Late endosomal microautophagy";"SUMOylation of transcription cofactors";"Aggrephagy";"Chaperone Mediated Autophagy"
XP_050315891.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050312978.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_050301376.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050314717.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050304297.1	2	KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608	"Aminoacyl-tRNA biosynthesis";"Platelet degranulation"
XP_050296303.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050315902.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050297469.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050310981.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580	"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence"
XP_050304863.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050310639.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_050297863.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050313447.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050300670.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050294936.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050311102.1	12	KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783	"Linoleic acid metabolism";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation"
XP_050313576.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050311438.1	4	Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_050294133.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-6783310;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Fanconi Anemia Pathway";"Separation of Sister Chromatids"
XP_050294639.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050305251.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-5136;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7338;MetaCyc: PWY-735	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis"
XP_050307955.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_050294673.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050309527.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_050314064.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_050298963.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050295365.1	4	Reactome: R-HSA-114608;Reactome: R-HSA-373753;Reactome: R-HSA-3000170;Reactome: R-HSA-446388	"Platelet degranulation";"Nephrin family interactions";"Syndecan interactions";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"
XP_050310480.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_050303487.1	6	MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_050309001.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050309634.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_050307938.1	29	Reactome: R-HSA-5693554;Reactome: R-HSA-6803207;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6803204;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693565;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69541;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-6804760	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human papillomavirus infection";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Stabilization of p53";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"Regulation of TP53 Activity through Methylation"
XP_050316031.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_050300823.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_050310518.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_050297005.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050293919.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050303639.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050302643.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050308772.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304020.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050307080.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050313846.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050294185.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_050308637.1	2	KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23	"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_050306835.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050311111.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_050308635.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_050310698.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_050311395.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307113.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_050301489.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050298115.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050304255.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex"
XP_050308381.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050296274.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_050299896.1	12	Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_050292968.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_050308199.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050314908.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_050310219.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050311522.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050303073.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050294498.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_050309781.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_050294720.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050313784.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050295219.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050308227.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_050309325.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050305686.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050311894.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050298676.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050304015.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050309749.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_050316209.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050300143.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050293952.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_050308642.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050306260.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050315597.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_050302388.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050305866.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050305646.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050298100.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_050302629.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050313342.1	3	Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7	"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism"
XP_050294427.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293394.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane"
XP_050310067.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_050311390.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050299116.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050294979.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050303367.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050293959.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_050292763.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism"
XP_050303571.1	7	Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050298105.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050294650.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050308784.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050307689.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050314338.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_050306364.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050301511.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050298311.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050294145.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050303848.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7736	"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis"
XP_050300227.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_050313925.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_050299917.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_050311392.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050310782.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_050299097.1	15	Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-69017	"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6"
XP_050312356.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_050314778.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050311403.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307880.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_050294610.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050301430.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050299263.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050308096.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050307072.1	5	MetaCyc: PWY-7817;MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system"
XP_050310343.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050310632.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_050312864.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_050304832.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050302364.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050298246.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050304777.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_050316411.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050307705.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306261.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050300591.1	18	MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7224	"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Purine deoxyribonucleosides salvage"
XP_050308259.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_050309719.1	7	MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_050312444.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050309768.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050306255.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050295053.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_050309152.1	3	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation"
XP_050297636.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_050308182.1	30	Reactome: R-HSA-187577;Reactome: R-HSA-2894862;Reactome: R-HSA-5610783;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-2644607;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-5607764;Reactome: R-HSA-202424	"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of GLI2 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling"
XP_050296742.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050294866.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050313963.1	5	KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_050296280.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050313246.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050304560.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_050307614.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_050314543.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_050302915.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_050315859.1	4	Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA"
XP_050311098.1	12	KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4	"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Ether lipid metabolism"
XP_050296102.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050304057.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_050294879.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050313615.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_050302422.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050299733.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050315091.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307224.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5743	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle"
XP_050310535.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400	"DNA Damage Recognition in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER"
XP_050308385.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050294562.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_050313152.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050299641.1	2	Reactome: R-HSA-75105;Reactome: R-HSA-383280	"Fatty acyl-CoA biosynthesis";"Nuclear Receptor transcription pathway"
XP_050312299.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_050311122.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_050315836.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050307856.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050306660.1	4	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_050305135.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050312862.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle"
XP_050303016.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_050299291.1	30	KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-199418;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-8941332;Reactome: R-HSA-6804758;Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-69202;Reactome: R-HSA-6804759;Reactome: R-HSA-111447;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389513;Reactome: R-HSA-198693;Reactome: R-HSA-8876198;Reactome: R-HSA-8948751;Reactome: R-HSA-69656;Reactome: R-HSA-198323;Reactome: R-HSA-211163;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614399	"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Negative regulation of the PI3K/AKT network";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Activity through Acetylation";"Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"Cyclin E associated events during G1/S transition";"Regulation of TP53 Activity through Association with Co-factors";"Activation of BAD and translocation to mitochondria";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CTLA4 inhibitory signaling";"AKT phosphorylates targets in the nucleus";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of PTEN stability and activity";"Cyclin A:Cdk2-associated events at S phase entry";"AKT phosphorylates targets in the cytosol";"AKT-mediated inactivation of FOXO1A";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Regulation of localization of FOXO transcription factors"
XP_050313429.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation"
XP_050296275.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050295744.1	10	Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8055	"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis"
XP_050309571.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050302088.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_050302411.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_050300317.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050297054.1	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
XP_050302241.1	4	Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_050313949.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_050314916.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_050292805.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050306741.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050315548.1	4	KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22	"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism"
XP_050298653.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_050297968.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_050307685.1	6	KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017	"Tryptophan metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_050303614.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294438.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050297778.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_050301861.1	31	MetaCyc: PWY-6519;MetaCyc: PWY-5973;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-7858;Reactome: R-HSA-2426168;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6113;MetaCyc: PWY-5142;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-5366;MetaCyc: PWY-5989;MetaCyc: PWY-7746;MetaCyc: PWY-5367;MetaCyc: PWY-5971;MetaCyc: PWYG-321;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8049;Reactome: R-HSA-75105;MetaCyc: PWY-5966-1;Reactome: R-HSA-199220;MetaCyc: PWY-8047;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-8012;MetaCyc: PWY-7723	"8-amino-7-oxononanoate biosynthesis I";"Cis-vaccenate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis";"Superpathway of mycolate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"Mycobacterial sulfolipid biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"";"ChREBP activates metabolic gene expression";"Biotin metabolism";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Bryostatin biosynthesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mupirocin biosynthesis";"Bacterial bioluminescence"
XP_050298951.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050302683.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_050314871.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050294286.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050315063.1	18	MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-5913	"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_050315345.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_050300026.1	6	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-5632927	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH3"
XP_050316308.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050311963.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306848.1	18	Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-6796648;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"Meiotic synapsis";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"TP53 Regulates Transcription of DNA Repair Genes";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_050310009.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_050296638.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_050316052.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050308964.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050300863.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_050302965.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050301759.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050301277.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050304013.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_050304699.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_050300668.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_050300086.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_050312331.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050293257.1	5	Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532	"Pyrimidine catabolism";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)"
XP_050294851.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050299224.1	10	Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847	"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"HATs acetylate histones"
XP_050315887.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050300882.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes"
XP_050296111.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300700.1	8	MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-5394	"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Betalamic acid biosynthesis"
XP_050296228.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_050304093.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_050309218.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050311817.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_050311773.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050314136.1	33	Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168325	"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis"
XP_050297595.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050308473.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_050302110.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_050295442.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_050303354.1	9	KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883	"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II"
XP_050296219.1	16	KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-7384	"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Itaconate degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_050297789.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-4641257;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8951664	"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of AXIN";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Neddylation"
XP_050298914.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050313277.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_050300196.1	27	Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746	"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"snRNP Assembly";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein"
XP_050313647.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;Reactome: R-HSA-4755609	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59"
XP_050296133.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303441.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050298583.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050303145.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_050315525.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-141430	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_050314824.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_050315184.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_050294404.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050297817.1	83	Reactome: R-HSA-8853659;Reactome: R-HSA-5654688;Reactome: R-HSA-5654695;Reactome: R-HSA-5654712;Reactome: R-HSA-9634285;Reactome: R-HSA-912631;Reactome: R-HSA-983695;Reactome: R-HSA-8851907;Reactome: R-HSA-1963640;Reactome: R-HSA-5663213;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-5654719;Reactome: R-HSA-9034864;Reactome: R-HSA-5654704;Reactome: R-HSA-8875555;Reactome: R-HSA-74751;Reactome: R-HSA-375165;Reactome: R-HSA-5654706;Reactome: R-HSA-112412;Reactome: R-HSA-74749;Reactome: R-HSA-5654726;Reactome: R-HSA-9607240;Reactome: R-HSA-512988;Reactome: R-HSA-9028335;Reactome: R-HSA-8856828;Reactome: R-HSA-1963642;Reactome: R-HSA-9026519;Reactome: R-HSA-8851805;Reactome: R-HSA-186763;Reactome: R-HSA-5637810;Reactome: R-HSA-1236382;Reactome: R-HSA-8865999;Reactome: R-HSA-5655302;Reactome: R-HSA-9645135;Reactome: R-HSA-6811558;Reactome: R-HSA-2428933;Reactome: R-HSA-1839117;Reactome: R-HSA-5654710;Reactome: R-HSA-8875656;Reactome: R-HSA-180336;Reactome: R-HSA-180292;Reactome: R-HSA-2871809;Reactome: R-HSA-2029482;Reactome: R-HSA-8853334;Reactome: R-HSA-2424491;Reactome: R-HSA-9028731;Reactome: R-HSA-8983432;Reactome: R-HSA-1433557;Reactome: R-HSA-5654727;Reactome: R-HSA-1295596;Reactome: R-HSA-5654700;Reactome: R-HSA-2871796;Reactome: R-HSA-5654733;Reactome: R-HSA-8856825;Reactome: R-HSA-389359;Reactome: R-HSA-2730905;Reactome: R-HSA-5654720;Reactome: R-HSA-5654693;Reactome: R-HSA-5654699;Reactome: R-HSA-182971;Reactome: R-HSA-388841;Reactome: R-HSA-109704;Reactome: R-HSA-391160;Reactome: R-HSA-1250196;Reactome: R-HSA-354194;Reactome: R-HSA-5655291;Reactome: R-HSA-210993;Reactome: R-HSA-9027284;Reactome: R-HSA-5654689;Reactome: R-HSA-179812;Reactome: R-HSA-167044;Reactome: R-HSA-5654732;Reactome: R-HSA-8853338;Reactome: R-HSA-2179392;Reactome: R-HSA-2219530;Reactome: R-HSA-1433559;Reactome: R-HSA-6807004;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8875360;Reactome: R-HSA-5655253;Reactome: R-HSA-912526	"RET signaling";"SHC-mediated cascade:FGFR1";"PI-3K cascade:FGFR2";"FRS-mediated FGFR4 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Regulation of signaling by CBL";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"MET activates PI3K/AKT signaling";"GRB2 events in ERBB2 signaling";"RHO GTPases Activate WASPs and WAVEs";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"SHC-mediated cascade:FGFR4";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR3";"MET activates RAP1 and RAC1";"Insulin receptor signalling cascade";"NCAM signaling for neurite out-growth";"FRS-mediated FGFR3 signaling";"SOS-mediated signalling";"Signal attenuation";"Negative regulation of FGFR1 signaling";"FLT3 Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Activated NTRK2 signals through PI3K";"Clathrin-mediated endocytosis";"PI3K events in ERBB2 signaling";"Activated NTRK2 signals through RAS";"MET activates RAS signaling";"Downstream signal transduction";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET activates PTPN11";"Signaling by FGFR1 in disease";"STAT5 Activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC-related events triggered by IGF1R";"Signaling by cytosolic FGFR1 fusion mutants";"PI-3K cascade:FGFR3";"MET receptor recycling";"SHC1 events in EGFR signaling";"GAB1 signalosome";"FCERI mediated Ca+2 mobilization";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by FGFR3 fusions in cancer";"DAP12 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Interleukin-15 signaling";"Signaling by SCF-KIT";"Negative regulation of FGFR2 signaling";"Spry regulation of FGF signaling";"FRS-mediated FGFR2 signaling";"FCERI mediated MAPK activation";"Negative regulation of FGFR4 signaling";"Cargo recognition for clathrin-mediated endocytosis";"CD28 dependent Vav1 pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"PI-3K cascade:FGFR4";"FRS-mediated FGFR1 signaling";"SHC-mediated cascade:FGFR2";"EGFR downregulation";"Costimulation by the CD28 family";"PI3K Cascade";"Signal regulatory protein family interactions";"SHC1 events in ERBB2 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR4 in disease";"Tie2 Signaling";"Erythropoietin activates RAS";"PI-3K cascade:FGFR1";"GRB2 events in EGFR signaling";"Signalling to RAS";"Negative regulation of FGFR3 signaling";"Signaling by FGFR3 point mutants in cancer";"EGFR Transactivation by Gastrin";"Constitutive Signaling by Aberrant PI3K in Cancer";"Regulation of KIT signaling";"Negative regulation of MET activity";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by FGFR2 in disease";"Interleukin receptor SHC signaling"
XP_050293532.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050312425.1	9	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
XP_050299927.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050307899.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation"
XP_050313618.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294094.1	26	Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-389977;Reactome: R-HSA-8955332;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-190840	"Aggrephagy";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_050313590.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050305136.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050313153.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050303362.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725	"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050301667.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050315419.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_050293125.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050314477.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_050305927.1	27	Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-6784531;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-3232142	"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"tRNA processing in the nucleus";"snRNP Assembly";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins"
XP_050299609.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_050311300.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050301520.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657	"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes"
XP_050297010.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041	"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis"
XP_050301668.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_050298912.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050299890.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050309217.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050314571.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_050304466.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050307655.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050308705.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050306043.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-168315	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Inhibition of Host mRNA Processing and RNA Silencing"
XP_050304406.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_050299316.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050315623.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape"
XP_050313285.1	7	KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050314359.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_050303270.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050305509.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_050302645.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050300475.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050307279.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III"
XP_050311412.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050309298.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_050308706.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050308554.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_050311170.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050313583.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050312684.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_050307454.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050311610.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050294433.1	4	Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events"
XP_050298091.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050293124.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050298689.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_050308110.1	5	Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_050297639.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050305154.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_050296234.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_050298144.1	10	MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2	"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism"
XP_050296117.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298900.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050292877.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050299547.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050308059.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050297655.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050304979.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050297848.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050316341.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311356.1	29	Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-112382;Reactome: R-HSA-427413	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression"
XP_050303822.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050310128.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050295366.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050306150.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_050314899.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050309695.1	11	MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-7124;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969	"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)"
XP_050296912.1	8	MetaCyc: PWY-7717;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7733;MetaCyc: PWY-7734;MetaCyc: PWY-7765	"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis II"
XP_050306987.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308760.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_050302605.1	8	KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1	"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_050310267.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050293004.1	12	Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221	"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis"
XP_050306812.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050311570.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050295085.1	6	Reactome: R-HSA-2029485;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-114508;Reactome: R-HSA-1489509	"Role of phospholipids in phagocytosis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling"
XP_050303074.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050310020.1	7	KEGG: 00650+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111	"Butanoate metabolism";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Synthesis of Ketone Bodies"
XP_050306258.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050305342.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_050304120.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy"
XP_050311775.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_050301224.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050300229.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_050314428.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297690.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050315603.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_050309773.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_050300575.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050302927.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_050310703.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_050305547.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050300799.1	12	KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476	"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (q) signalling events"
XP_050293608.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763	"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction"
XP_050313510.1	8	Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273	"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis"
XP_050300117.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_050315958.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"AURKA Activation by TPX2"
XP_050304175.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050292808.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050313621.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050304197.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427	"Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains"
XP_050298650.1	2	KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_050314999.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_050298641.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050295976.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_050299579.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050312720.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050304586.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050313504.1	4	Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;MetaCyc: PWY-8026;Reactome: R-HSA-6807062	"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol"
XP_050306469.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050308972.1	3	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK"
XP_050311569.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050295252.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050313540.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314556.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050308880.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_050306733.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050306584.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050300009.1	10	MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Inositol phosphate metabolism";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)"
XP_050310033.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050309106.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311683.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050304512.1	11	MetaCyc: PWY-6999;MetaCyc: PWY-5695;MetaCyc: PWY-6538;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6596;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608	"Theophylline degradation";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation III"
XP_050311674.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050315118.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_050309080.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050304756.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050297006.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_050303514.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050300357.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050301982.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway"
XP_050295069.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_050300023.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050306202.1	42	Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-977225;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-5334118;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-427413;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-73728;Reactome: R-HSA-110328;Reactome: R-HSA-3214858;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-110330;Reactome: R-HSA-4551638;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-110329;Reactome: R-HSA-3214841;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-606279;Reactome: R-HSA-427389;Reactome: R-HSA-5693565;Reactome: R-HSA-2559580	"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Amyloid fiber formation";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"DNA methylation";"Meiotic recombination";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"NoRC negatively regulates rRNA expression";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"PRC2 methylates histones and DNA";"HCMV Early Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RMTs methylate histone arginines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HCMV Late Events";"Estrogen-dependent gene expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"SUMOylation of chromatin organization proteins";"Meiotic synapsis";"HDACs deacetylate histones";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"PKMTs methylate histone lysines";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"Deposition of new CENPA-containing nucleosomes at the centromere";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Oxidative Stress Induced Senescence"
XP_050305867.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050297109.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837	"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion homeostasis";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases"
XP_050311015.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050307053.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_050313003.1	14	Reactome: R-HSA-434316;MetaCyc: PWY-6351;Reactome: R-HSA-418217;KEGG: 04070+3.1.4.11;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;MetaCyc: PWY-6367;Reactome: R-HSA-399997	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G beta:gamma signalling through PLC beta";"Phosphatidylinositol signaling system";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"Ca2+ pathway";"D-myo-inositol-5-phosphate metabolism";"Acetylcholine regulates insulin secretion"
XP_050307051.1	12	Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-1169408;Reactome: R-HSA-450408;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72662	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Translation initiation complex formation";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_050316306.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050316129.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA"
XP_050305108.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050299789.1	3	KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation"
XP_050305116.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050311873.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes"
XP_050303154.1	32	Reactome: R-HSA-72086;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-112382;Reactome: R-HSA-167242	"mRNA Capping";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_050313400.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050301922.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050296790.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050293381.1	4	MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041	"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II"
XP_050305929.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-159230	"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_050300772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050311420.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050304064.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_050307242.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050314710.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050293482.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_050293828.1	12	Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290	"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_050293160.1	5	MetaCyc: PWY-6289;Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7	"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis"
XP_050300744.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050301606.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_050304115.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813	"Aggrephagy";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids"
XP_050295533.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050300775.1	3	Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807	"Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism"
XP_050303082.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050306197.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-1236978;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-5668541;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-174113	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Degradation of DVL";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1"
XP_050310550.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_050303566.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050295345.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050294154.1	12	Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA"
XP_050313740.1	2	Reactome: R-HSA-189085;Reactome: R-HSA-2129379	"Digestion of dietary carbohydrate";"Molecules associated with elastic fibres"
XP_050307874.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination"
XP_050314560.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050314993.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_050298112.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_050293014.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_050299743.1	6	KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050305966.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050293210.1	5	Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630	"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3"
XP_050294384.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_050299127.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050314458.1	6	MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Biotin metabolism";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050306977.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050313974.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050298674.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050300547.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050298943.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050306322.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_050310458.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_050312395.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_050307413.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050303543.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050315981.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050314297.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_050305106.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_050298855.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050312423.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation"
XP_050309807.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050308286.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050303172.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050304590.1	6	MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis"
XP_050306912.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050312991.1	14	Reactome: R-HSA-416476;Reactome: R-HSA-399997;MetaCyc: PWY-6367;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-418217;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-434316	"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Ca2+ pathway";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G beta:gamma signalling through PLC beta";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_050311339.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050292827.1	18	Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166	"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA"
XP_050301241.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050294930.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050302709.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050294056.1	5	KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-196757	"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines"
XP_050313140.1	11	KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"FOXO-mediated transcription of cell death genes";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway"
XP_050305516.1	8	Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination"
XP_050311380.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050311658.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050297925.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion"
XP_050294814.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880	"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Ub-specific processing proteases"
XP_050312110.1	1	Reactome: R-HSA-419771	"Opsins"
XP_050313234.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050316072.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_050310852.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_050313203.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_050313571.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation"
XP_050294672.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_050316163.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050311018.1	3	Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1	"Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism"
XP_050313609.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050298507.1	10	Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644	"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"EGFR downregulation";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair"
XP_050297763.1	5	Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5610787	"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'off' state"
XP_050312920.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_050297113.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827	"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_050312318.1	182	Reactome: R-HSA-6804757;Reactome: R-HSA-9604323;Reactome: R-HSA-5689880;Reactome: R-HSA-110312;Reactome: R-HSA-72706;Reactome: R-HSA-8863795;Reactome: R-HSA-4641263;Reactome: R-HSA-5696400;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-6781827;Reactome: R-HSA-69601;Reactome: R-HSA-168927;Reactome: R-HSA-1236382;Reactome: R-HSA-5696397;Reactome: R-HSA-202424;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-8948751;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-4641258;Reactome: R-HSA-5654726;Reactome: R-HSA-6781823;Reactome: R-HSA-2173788;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-6791226;Reactome: R-HSA-5205685;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-2894862;Reactome: R-HSA-5632684;Reactome: R-HSA-162588;Reactome: R-HSA-209543;Reactome: R-HSA-168928;Reactome: R-HSA-211733;Reactome: R-HSA-69231;Reactome: R-HSA-9613829;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-8951664;Reactome: R-HSA-174490;Reactome: R-HSA-450321;Reactome: R-HSA-5675221;Reactome: R-HSA-8875360;Reactome: R-HSA-1236974;Reactome: R-HSA-9013507;Reactome: R-HSA-2559580;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-175474;Reactome: R-HSA-5357956;Reactome: R-HSA-5696395;Reactome: R-HSA-3769402;Reactome: R-HSA-6804756;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8849469;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-2173791;Reactome: R-HSA-1799339;Reactome: R-HSA-2672351;Reactome: R-HSA-6782135;Reactome: R-HSA-2559582;Reactome: R-HSA-1253288;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-6783310;Reactome: R-HSA-4641257;Reactome: R-HSA-209560;Reactome: R-HSA-5696394;Reactome: R-HSA-2173796;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-977225;Reactome: R-HSA-5655862;Reactome: R-HSA-5675482;Reactome: R-HSA-75815;Reactome: R-HSA-2173795;Reactome: R-HSA-6782210;Reactome: R-HSA-5362768;Reactome: R-HSA-9646399;Reactome: R-HSA-174048;Reactome: R-HSA-450408;Reactome: R-HSA-2565942;Reactome: R-HSA-9645460;Reactome: R-HSA-72764;Reactome: R-HSA-937042;Reactome: R-HSA-8852276;Reactome: R-HSA-8876493;Reactome: R-HSA-975110;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-901032;Reactome: R-HSA-1169408;Reactome: R-HSA-68949;Reactome: R-HSA-936440;Reactome: R-HSA-445989;Reactome: R-HSA-72649;Reactome: R-HSA-2644606;Reactome: R-HSA-975957;Reactome: R-HSA-3134975;Reactome: R-HSA-5689896;Reactome: R-HSA-937039;Reactome: R-HSA-69017;Reactome: R-HSA-2979096;Reactome: R-HSA-69481;Reactome: R-HSA-1358803;Reactome: R-HSA-205043;Reactome: R-HSA-8854050;Reactome: R-HSA-5689901;Reactome: R-HSA-532668;Reactome: R-HSA-975144;Reactome: R-HSA-168638;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9615710;Reactome: R-HSA-68827;Reactome: R-HSA-174184;Reactome: R-HSA-5689877;Reactome: R-HSA-912631;Reactome: R-HSA-8939236;Reactome: R-HSA-5656121;Reactome: R-HSA-450302;Reactome: R-HSA-400253;Reactome: R-HSA-5658442;Reactome: R-HSA-72689;Reactome: R-HSA-6807004;Reactome: R-HSA-110314;Reactome: R-HSA-2122948;Reactome: R-HSA-174113;Reactome: R-HSA-975163;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-9014325;Reactome: R-HSA-5654732;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-5685942;Reactome: R-HSA-69541;Reactome: R-HSA-9633012;Reactome: R-HSA-2691232;Reactome: R-HSA-8866654;Reactome: R-HSA-182971;Reactome: R-HSA-2408557;Reactome: R-HSA-3785653;Reactome: R-HSA-3322077;Reactome: R-HSA-349425;Reactome: R-HSA-201681;Reactome: R-HSA-2871837;Reactome: R-HSA-5693607;Reactome: R-HSA-9033241;Reactome: R-HSA-8856825;Reactome: R-HSA-2559585;Reactome: R-HSA-5656169;Reactome: R-HSA-5654733;Reactome: R-HSA-1295596;Reactome: R-HSA-9636383;Reactome: R-HSA-72695;Reactome: R-HSA-1169091;Reactome: R-HSA-6804760;Reactome: R-HSA-5654727;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-192823;Reactome: R-HSA-2122947;Reactome: R-HSA-179409;Reactome: R-HSA-5357905;Reactome: R-HSA-9637628;Reactome: R-HSA-937041;Reactome: R-HSA-5684264	"Regulation of TP53 Degradation";"Negative regulation of NOTCH4 signaling";"Ub-specific processing proteases";"Translesion synthesis by REV1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Downregulation of ERBB2 signaling";"Regulation of FZD by ubiquitination";"Dual Incision in GG-NER";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1, RIP1-mediated IKK complex recruitment";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"Regulation of PTEN stability and activity";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Degradation of DVL";"Negative regulation of FGFR1 signaling";"Formation of TC-NER Pre-Incision Complex";"Downregulation of TGF-beta receptor signaling";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Pink/Parkin Mediated Mitophagy";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Hedgehog 'on' state";"Budding and maturation of HIV virion";"p75NTR recruits signalling complexes";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cyclin D associated events in G1";"Chaperone Mediated Autophagy";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"Neddylation";"Membrane binding and targetting of GAG proteins";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Negative regulation of MAPK pathway";"InlB-mediated entry of Listeria monocytogenes into host cell";"ER-Phagosome pathway";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Oxidative Stress Induced Senescence";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Assembly Of The HIV Virion";"TNFR1-induced NFkappaB signaling pathway";"Formation of Incision Complex in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SRP-dependent cotranslational protein targeting to membrane";"Stimuli-sensing channels";"Dual incision in TC-NER";"Senescence-Associated Secretory Phenotype (SASP)";"Downregulation of ERBB4 signaling";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Fanconi Anemia Pathway";"Degradation of AXIN";"NF-kB is activated and signals survival";"DNA Damage Recognition in GG-NER";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"ABC-family proteins mediated transport";"UCH proteinases";"Iron uptake and transport";"Amyloid fiber formation";"Translesion synthesis by POLK";"Regulation of necroptotic cell death";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Aggrephagy";"APC/C:Cdc20 mediated degradation of Cyclin B";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition";"Alpha-protein kinase 1 signaling pathway";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"InlA-mediated entry of Listeria monocytogenes into host cells";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"ER Quality Control Compartment (ERQC)";"ISG15 antiviral mechanism";"Orc1 removal from chromatin";"Negative regulators of DDX58/IFIH1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Translation initiation complex formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of innate immune responses to cytosolic DNA";"Ovarian tumor domain proteases";"IRAK1 recruits IKK complex";"CDK-mediated phosphorylation and removal of Cdc6";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"G2/M Checkpoints";"Downregulation of ERBB2:ERBB3 signaling";"NRIF signals cell death from the nucleus";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Metalloprotease DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Late endosomal microautophagy";"CDT1 association with the CDC6:ORC:origin complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Josephin domain DUBs";"Regulation of signaling by CBL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Translesion synthesis by POLI";"activated TAK1 mediates p38 MAPK activation";"Circadian Clock";"Regulation of RAS by GAPs";"Formation of a pool of free 40S subunits";"Negative regulation of MET activity";"Recognition of DNA damage by PCNA-containing replication complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulation of FGFR3 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"HDR through Homologous Recombination (HRR)";"Stabilization of p53";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"EGFR downregulation";"Selenocysteine synthesis";"Myoclonic epilepsy of Lafora";"Glycogen synthesis";"Autodegradation of the E3 ubiquitin ligase COP1";"TCF dependent signaling in response to WNT";"FCERI mediated NF-kB activation";"Processing of DNA double-strand break ends";"Peroxisomal protein import";"Cargo recognition for clathrin-mediated endocytosis";"Oncogene Induced Senescence";"Termination of translesion DNA synthesis";"Negative regulation of FGFR4 signaling";"Spry regulation of FGF signaling";"Prevention of phagosomal-lysosomal fusion";"Formation of the ternary complex, and subsequently, the 43S complex";"Activation of NF-kappaB in B cells";"Regulation of TP53 Activity through Methylation";"Negative regulation of FGFR2 signaling";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Viral mRNA Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TNFR1 signaling";"Modulation by Mtb of host immune system";"IKK complex recruitment mediated by RIP1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation"
XP_050301718.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050295396.1	4	Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_050298856.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs"
XP_050298591.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_050314299.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050293168.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050311983.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311404.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050299726.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050307462.1	5	Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-427413	"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression"
XP_050307596.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_050304087.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_050303269.1	5	Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_050294648.1	11	Reactome: R-HSA-6796648;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-2871796;Reactome: R-HSA-1912408;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803	"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"FCERI mediated MAPK activation";"Pre-NOTCH Transcription and Translation";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_050308152.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050302490.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_050299713.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277	"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex"
XP_050308716.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050310868.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050293306.1	15	MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-6886	"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)"
XP_050296105.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050297239.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1"
XP_050293040.1	17	Reactome: R-HSA-9022692;Reactome: R-HSA-5663220;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-174178;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2500257;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Regulation of MECP2 expression and activity";"RHO GTPases Activate Formins";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Resolution of Sister Chromatid Cohesion";"Human cytomegalovirus infection";"Human papillomavirus infection";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_050305963.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_050316037.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050311766.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_050298254.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050306367.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_050308975.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_050315124.1	1	Reactome: R-HSA-375276	"Peptide ligand-binding receptors"
XP_050295880.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050296824.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-162594	"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle"
XP_050306473.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050303104.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050293502.1	11	Reactome: R-HSA-1660517;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-109704;Reactome: R-HSA-1660499;MetaCyc: PWY-6352	"Synthesis of PIPs at the late endosome membrane";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Macroautophagy";"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis"
XP_050315408.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050299782.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050293950.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050313938.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_050304251.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_050294014.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050316034.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_050307741.1	11	Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange"
XP_050296046.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050294354.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050313557.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint"
XP_050308747.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_050304275.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions"
XP_050313513.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_050295040.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764	"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling"
XP_050305565.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050309901.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050296960.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050307949.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_050307841.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050308669.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050312905.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050310241.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050298846.1	4	Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828	"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis"
XP_050293154.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-264870	"Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins"
XP_050294484.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_050314580.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050294489.1	4	KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834	"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III"
XP_050306647.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping"
XP_050295728.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_050311174.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050300732.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_050302607.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050300790.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050308111.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050306718.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_050306810.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050295364.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_050307370.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050305164.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050294721.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_050308177.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050309344.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_050313840.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_050301886.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway"
XP_050303880.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050313090.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_050294816.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_050302969.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_050305977.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296789.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_050303687.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_050299738.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050295765.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050303140.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_050301687.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050315569.1	5	Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism"
XP_050304246.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_050315009.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_050300836.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_050294480.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118	"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors"
XP_050297963.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_050298945.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050315793.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_050311142.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_050297172.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_050304164.1	4	MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism"
XP_050293087.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_050299565.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_050305642.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050296170.1	3	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695	"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation"
XP_050298130.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050307329.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation"
XP_050296271.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_050303084.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050307492.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_050310596.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_050310070.1	5	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050303925.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050302018.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050304647.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050313563.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050296180.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050310389.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I"
XP_050299959.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050316273.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050315544.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050309280.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050292967.1	1	Reactome: R-HSA-110357	"Displacement of DNA glycosylase by APEX1"
XP_050313528.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050307022.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_050312370.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_050305303.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_050312259.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_050304369.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_050298110.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050300851.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_050311107.1	18	KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Synthesis of PA";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE"
XP_050295306.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_050305302.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050316401.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_050293113.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway"
XP_050308824.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_050297728.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_050306361.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050310021.1	7	KEGG: 00650+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111	"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Mevalonate degradation";"Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Synthesis of Ketone Bodies"
XP_050302630.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050302693.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050313446.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_050302697.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050303241.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_050293805.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050309116.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050301424.1	16	Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-426496	"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs"
XP_050310234.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050315303.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_050312524.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050293114.1	8	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_050314137.1	33	Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220	"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"HCMV Late Events";"RHO GTPases Activate Formins"
XP_050292733.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_050307451.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050304630.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_050309345.1	8	KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis"
XP_050314766.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050301707.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-6798695	"Glycosphingolipid metabolism";"Neutrophil degranulation"
XP_050314612.1	2	Reactome: R-HSA-196299;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_050310226.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_050314238.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_050298175.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_050292769.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_050312349.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050304412.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050302087.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_050301072.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050313531.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050307535.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_050301255.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_050311871.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_050294823.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050292836.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_050302415.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050302033.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050292764.1	6	KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050298713.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_050307408.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050305649.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050313999.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_050309952.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050298127.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050310455.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050297422.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_050311742.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-204005	"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport"
XP_050298974.1	12	MetaCyc: PWY-6969;MetaCyc: PWY-7854;MetaCyc: PWY-5749;MetaCyc: PWY-6728;KEGG: 00720+4.1.3.25;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-5744;MetaCyc: PWY-7295;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;KEGG: 00660+4.1.3.25	"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Itaconate degradation";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV";"Glyoxylate assimilation";"L-arabinose degradation IV";"Pyruvate metabolism";"Chitin degradation to ethanol";"C5-Branched dibasic acid metabolism"
XP_050311099.1	12	MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4	"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism"
XP_050313503.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050300927.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_050293590.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_050299764.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050298225.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050297454.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_050302270.1	5	MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis"
XP_050295794.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_050299934.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050309698.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050306554.1	7	KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway"
XP_050309601.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050309189.1	5	Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_050303549.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_050314582.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_050313083.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050314104.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_050313878.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_050294977.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050307590.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050302611.1	12	MetaCyc: PWY-6728;KEGG: 00630+6.4.1.3;MetaCyc: PWYG-321;KEGG: 00720+6.4.1.3;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.3;MetaCyc: PWY-7384;MetaCyc: PWY-5789;KEGG: 00280+6.4.1.3;Reactome: R-HSA-196780;Reactome: R-HSA-71032;Reactome: R-HSA-3371599	"Methylaspartate cycle";"Glyoxylate and dicarboxylate metabolism";"";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Biotin transport and metabolism";"Propionyl-CoA catabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_050310913.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_050312190.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050307393.1	12	KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-174362;MetaCyc: PWY-5278;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.1.25;Reactome: R-HSA-2408550	"Selenocompound metabolism";"Monobactam biosynthesis";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Sulfite oxidation III";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"
XP_050293934.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_050312150.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition"
XP_050310012.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_050311880.1	9	Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-196780;MetaCyc: PWY-6146;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6142	"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_050299807.1	2	Reactome: R-HSA-8950505;Reactome: R-HSA-1237112	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway"
XP_050315893.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050305563.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_050314776.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_050293263.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_050297864.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050316408.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_050314713.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050309175.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_050293953.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_050304223.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6922	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis"
XP_050297317.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_050302104.1	10	Reactome: R-HSA-70263;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7003;MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-8004	"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I"
XP_050300743.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050299094.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_050294635.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050310273.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050297316.1	52	Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-73780;Reactome: R-HSA-73779;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-75953;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167162	"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape"
XP_050309212.1	7	MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183	"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_050307580.1	13	Reactome: R-HSA-3000178;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090	"ECM proteoglycans";"Crosslinking of collagen fibrils";"Signaling by PDGF";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Laminin interactions";"Anchoring fibril formation";"Collagen chain trimerization";"Collagen degradation";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures"
XP_050309864.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050303335.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_050306122.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_050297509.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050302918.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517	"Ca2+ pathway";"cGMP effects";"Rap1 signalling"
XP_050314384.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050294251.1	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism"
XP_050294355.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_050302581.1	5	MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527	"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation"
XP_050316257.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_050310982.1	5	Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_050303068.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_050308667.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_050304674.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050308826.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"HCMV Late Events";"snRNP Assembly";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins"
XP_050297556.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_050303197.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026	"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_050301981.1	7	KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1	"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection"
XP_050306058.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050298108.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050298117.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_050297063.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-5578775	"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis"
XP_050315145.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712	"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport"
XP_050307070.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050306517.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050306259.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050315104.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_050301062.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling"
XP_050299033.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_050309777.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660	"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (i) signalling events";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway"
XP_050311958.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050311332.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_050293585.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle"
XP_050313425.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050296724.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA"
XP_050311394.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050307378.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_050297552.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295769.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050310688.1	3	Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation"
XP_050312183.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050302678.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050301618.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_050312420.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050295948.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050306914.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_050306363.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050292734.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_050314336.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_050308985.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050297748.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050299497.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_050293983.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5856;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855	"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)"
XP_050296047.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_050316364.1	6	MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_050293398.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050313724.1	5	KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891	"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)"
XP_050302632.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050306079.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_050298746.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_050304138.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050302289.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_050306806.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_050296487.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_050295552.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_050316305.1	1	Reactome: R-HSA-6782861	"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_050299626.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148	"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Lipophagy";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050313582.1	5	Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050311133.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_050314289.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_050314510.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-8875656	"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"MET receptor recycling"
XP_050309895.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_050306350.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_050303445.1	9	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_050295924.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_050305807.1	1	Reactome: R-HSA-373752	"Netrin-1 signaling"
XP_050314316.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050307987.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050294530.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_050316286.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050304561.1	16	Reactome: R-HSA-5602498;Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-5603037;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-5603041;Reactome: R-HSA-5602680;Reactome: R-HSA-975871;Reactome: R-HSA-1810476;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6811558;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702	"MyD88 deficiency (TLR2/4)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR5)";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"MyD88 cascade initiated on plasma membrane";"RIP-mediated NFkB activation via ZBP1";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ER-Phagosome pathway";"Interleukin-1 signaling"
XP_050302386.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050314364.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_050294298.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050301699.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_050305138.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_050302730.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050311979.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050310772.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_050305481.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_050292766.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_050304068.1	2	Reactome: R-HSA-8964539;Reactome: R-HSA-2151201	"Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_050315646.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_050310071.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress"
XP_050293780.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050311426.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_050298910.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_050307447.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050293603.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_050299650.1	13	Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883	"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II"
XP_050309476.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_050313391.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050303001.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_050310211.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_050295881.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_050315960.1	18	MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism"
XP_050308254.1	4	Reactome: R-HSA-3214847;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis"
XP_050314442.1	4	MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49	"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism"
XP_050295706.1	5	MetaCyc: PWY-5269;MetaCyc: PWY-7817;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483148	"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PG"
XP_050313113.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_050304100.1	7	MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13	"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis"
XP_050296858.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_050314663.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761	"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)"
XP_050299453.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-381426;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-201722	"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex"
XP_050296203.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation"
XP_050293505.1	10	MetaCyc: PWY-6352;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;Reactome: R-HSA-109704;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137	"3-phosphoinositide biosynthesis";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"PI3K Cascade";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism"
XP_050306516.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection"
XP_050311154.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_050293939.1	3	Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627	"Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6"
XP_050299841.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050305981.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050296129.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050314715.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050297572.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050308657.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_050304965.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_050307548.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"Human papillomavirus infection"
XP_050302572.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_050305706.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050297868.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16	"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism"
XP_050297358.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_050295448.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050313247.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_050292930.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050295745.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)"
XP_050311780.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-429958	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease"
XP_050301488.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050310761.1	3	KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_050315763.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_050307034.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_050295810.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_050297876.1	3	KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9	"One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis"
XP_050315800.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050304435.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_050296169.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;Reactome: R-HSA-8853383	"Neutrophil degranulation";"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_050296106.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050295803.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_050296127.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050306990.1	4	KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193	"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_050308665.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_050316132.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_050314478.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_050304664.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050306961.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_050293504.1	10	Reactome: R-HSA-5668599;Reactome: R-HSA-168138;Reactome: R-HSA-1660517;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-109704	"RHO GTPases Activate NADPH Oxidases";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the late endosome membrane";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Macroautophagy";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade"
XP_050309848.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050303136.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis"
XP_050307449.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050296770.1	6	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_050306359.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050314109.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050297351.1	5	Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-6782210	"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_050313791.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050308255.1	4	Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437	"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation"
XP_050311049.1	4	Reactome: R-HSA-1237112;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_050297234.1	4	KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage"
XP_050300894.1	3	KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B	"Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates"
XP_050301503.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-75815;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-68949;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5607764;Reactome: R-HSA-5610780;Reactome: R-HSA-9020702;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5658442	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ubiquitin-dependent degradation of Cyclin D";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"Hedgehog 'on' state";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Orc1 removal from chromatin";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CLEC7A (Dectin-1) signaling";"Degradation of GLI1 by the proteasome";"Interleukin-1 signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs"
XP_050311093.1	18	MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417	"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Anandamide biosynthesis II";"Synthesis of PA";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_050310870.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_050296714.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_050311109.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050311606.1	11	Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-69231;Reactome: R-HSA-5693565	"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_050293438.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_050310557.1	11	KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5154;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790;Reactome: R-HSA-500753;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-7400;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686	"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050312690.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050315075.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050306086.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_050305828.1	19	MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;Reactome: R-HSA-71403;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-561	"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_050303860.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_050295276.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_050308639.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-190861;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-8955332	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Gap junction assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Aggrephagy";"Kinesins";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Carboxyterminal post-translational modifications of tubulin"
XP_050313639.1	5	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination"
XP_050313561.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_050304540.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578998	"Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)"
XP_050300724.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-983168	"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050312694.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050313783.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_050298866.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050316025.1	6	Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656	"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis"
XP_050292728.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_050298922.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050292958.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_050303129.1	6	Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_050303014.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane"
XP_050299095.1	15	Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-174048	"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_050303385.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_050303620.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050299584.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_050305647.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_050292806.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_050310675.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050305375.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_050312352.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_050303778.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching"
XP_050295964.1	13	MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-6383	"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_050304258.1	44	Reactome: R-HSA-9634638;Reactome: R-HSA-8943724;Reactome: R-HSA-1295596;Reactome: R-HSA-5654727;Reactome: R-HSA-5674135;Reactome: R-HSA-5673001;Reactome: R-HSA-456926;Reactome: R-HSA-2559585;Reactome: R-HSA-112409;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5654733;Reactome: R-HSA-170968;Reactome: R-HSA-2559582;Reactome: R-HSA-375165;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482;Reactome: R-HSA-982772;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5663213;Reactome: R-HSA-9627069;Reactome: R-HSA-8939211;Reactome: R-HSA-5654732;Reactome: R-HSA-2559580;Reactome: R-HSA-6811558;Reactome: R-HSA-881907;Reactome: R-HSA-445144;Reactome: R-HSA-444257;Reactome: R-HSA-5668599;Reactome: R-HSA-162658;Reactome: R-HSA-6802952;Reactome: R-HSA-450341;Reactome: R-HSA-3371453;Reactome: R-HSA-8940973;Reactome: R-HSA-5675221;Reactome: R-HSA-879415;Reactome: R-HSA-202670;Reactome: R-HSA-198753;Reactome: R-HSA-74749;Reactome: R-HSA-5654726;Reactome: R-HSA-6802948;Reactome: R-HSA-9635465;Reactome: R-HSA-5674499	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of PTEN gene transcription";"Spry regulation of FGF signaling";"Negative regulation of FGFR2 signaling";"MAP2K and MAPK activation";"RAF/MAP kinase cascade";"Thrombin signalling through proteinase activated receptors (PARs)";"Oncogene Induced Senescence";"RAF-independent MAPK1/3 activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of FGFR4 signaling";"Frs2-mediated activation";"Senescence-Associated Secretory Phenotype (SASP)";"NCAM signaling for neurite out-growth";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation";"Growth hormone receptor signaling";"Signaling downstream of RAS mutants";"mTOR signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of the apoptosome activity";"ESR-mediated signaling";"Negative regulation of FGFR3 signaling";"Oxidative Stress Induced Senescence";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Signal transduction by L1";"RSK activation";"RHO GTPases Activate NADPH Oxidases";"Golgi Cisternae Pericentriolar Stack Reorganization";"Signaling by BRAF and RAF fusions";"Activation of the AP-1 family of transcription factors";"Regulation of HSF1-mediated heat shock response";"RUNX2 regulates osteoblast differentiation";"Negative regulation of MAPK pathway";"Advanced glycosylation endproduct receptor signaling";"ERKs are inactivated";"ERK/MAPK targets";"Signal attenuation";"Negative regulation of FGFR1 signaling";"Signaling by high-kinase activity BRAF mutants";"Suppression of apoptosis";"Negative feedback regulation of MAPK pathway"
XP_050312667.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050312733.1	2	KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399	"Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum"
XP_050307192.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_050299028.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_050297368.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_050296662.1	5	MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_050308066.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050303922.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_050295323.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_050302612.1	12	KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;KEGG: 00640+6.4.1.3;MetaCyc: PWY-5743;MetaCyc: PWYG-321;KEGG: 00630+6.4.1.3;MetaCyc: PWY-6728;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-5789;KEGG: 00280+6.4.1.3;Reactome: R-HSA-71032	"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"3-hydroxypropanoate cycle";"";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Valine, leucine and isoleucine degradation";"Propionyl-CoA catabolism"
XP_050294990.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_050296698.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050314684.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_050315039.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_050311626.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050294972.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050310096.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050302393.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050303031.1	8	KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1	"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_050303106.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_050304198.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_050297630.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050305777.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_050313126.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_050310158.1	14	MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725	"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_050295995.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375281	"G alpha (q) signalling events";"Hormone ligand-binding receptors"
XP_050296387.1	11	MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6596;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6608;MetaCyc: PWY-7185;MetaCyc: PWY-6607;MetaCyc: PWY-6606	"Inosine 5'-phosphate degradation";"Purine metabolism";"Pyrimidine metabolism";"Adenosine nucleotides degradation I";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II"
XP_050296568.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050308956.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_050302966.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-3000497;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888	"Platelet sensitization by LDL";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"VLDL clearance";"LDL remodeling";"LDL clearance";"VLDL assembly";"Cell surface interactions at the vascular wall";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Chylomicron clearance";"Chylomicron remodeling";"Scavenging by Class H Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly"
XP_050292851.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_050298322.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050306103.1	13	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation"
XP_050308791.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_050314540.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485	"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"PLC beta mediated events";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis"
XP_050311892.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_050307220.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_050307951.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_050307471.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_050305477.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050310680.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_050294740.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_050299838.1	4	KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II"
XP_050309624.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050310644.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_050299452.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-201722	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Formation of the beta-catenin:TCF transactivating complex"
XP_050300405.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_050296868.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_050301847.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_050300954.1	2	KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)"
XP_050296869.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050297598.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway"
XP_050295329.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_050305784.1	29	Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-427413	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression"
XP_050305478.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_050302062.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_050303126.1	6	Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6898;MetaCyc: PWY-6908	"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)"
XP_050315839.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050296538.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_050311977.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050298320.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050302005.1	3	MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism"
XP_050298554.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050313941.1	7	MetaCyc: PWY-7221;MetaCyc: PWY-6596;Reactome: R-HSA-73817;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205	"Guanosine ribonucleotides de novo biosynthesis";"Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine metabolism"
XP_050300549.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_050314704.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_050310741.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_050304792.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050316035.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_050292853.1	13	Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-202433;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;Reactome: R-HSA-2871796;Reactome: R-HSA-9027277;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052	"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"FCERI mediated MAPK activation";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis"
XP_050309104.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050315895.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050297014.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_050299161.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_050304758.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_050316361.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_050302857.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_050301751.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_050306510.1	7	KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway"
XP_050305371.1	12	MetaCyc: PWY-5856;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-7230;MetaCyc: PWY-5873;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_050315833.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050311382.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050292767.1	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050300048.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_050299742.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050298911.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050309584.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050305615.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_050295295.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_050302809.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_050312844.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050300146.1	5	Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857	"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Glycosaminoglycan degradation";"Keratan sulfate degradation"
XP_050314886.1	3	Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841	"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines"
XP_050314664.1	5	MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_050298315.1	11	Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1	"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"IRF3-mediated induction of type I IFN";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Human papillomavirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection"
XP_050309279.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050293002.1	3	MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17	"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism"
XP_050293412.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_050307031.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_050304507.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation"
XP_050312737.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_050299093.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_050314202.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_050294932.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-9656256;Reactome: R-HSA-9656255;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-5649702	"Cleavage of the damaged pyrimidine";"Defective OGG1 Substrate Processing";"Defective OGG1 Substrate Binding";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_050302569.1	13	Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;KEGG: 05165+2.7.11.1	"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human papillomavirus infection"
XP_050311405.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050308977.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_050295683.1	8	Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_050314482.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_050311744.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_050297843.1	6	Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33	"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis"
XP_050308508.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_050316073.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_050303377.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_050315835.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_050294871.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_050295885.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_050299735.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_050309510.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097	"Human papillomavirus infection";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway"
XP_050298318.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_050303440.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050309582.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway"
XP_050306365.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_050308113.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_050295515.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_050297312.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER"
XP_050298397.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_050302553.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_050296053.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050307054.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_050292938.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_050310977.1	5	Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_050316122.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_050298240.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_050302696.1	6	KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_050303137.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-190873	"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation"
XP_050295713.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_050315759.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_050304795.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_050314847.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_050302926.1	4	MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)"
XP_050301461.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_050309420.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_050313415.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_050308252.1	4	KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones"
XP_050300128.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_050298698.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_050296172.1	12	Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;KEGG: 00600+3.2.1.23;Reactome: R-HSA-8853383;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23	"HS-GAG degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Other glycan degradation";"Sphingolipid metabolism";"Lysosomal oligosaccharide catabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_050296948.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_050300632.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_050306813.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_050311072.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_050301474.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_050314066.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050296034.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_050294856.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_050310269.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050298388.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_050314889.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_050298917.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_050301567.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_050297852.1	8	Reactome: R-HSA-1855183;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6664;MetaCyc: PWY-6372	"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)"
XP_050294641.1	11	Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-5687128;Reactome: R-HSA-8862803;Reactome: R-HSA-2559582;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-1912408	"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MAPK6/MAPK4 signaling";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"Pre-NOTCH Transcription and Translation"
XP_050314448.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_050294122.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050297749.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_050312333.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_050315927.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_050302962.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_050313062.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_050295782.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_050312186.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_050309652.1	4	Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_050304650.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_050295799.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_050314807.1	3	Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154	"Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase"
XP_050294533.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_050296788.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_050304088.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_050314063.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_050310072.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_050304801.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_050298864.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_050310448.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_050306036.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_050295224.1	1	Reactome: R-HSA-72731	"Recycling of eIF2:GDP"
XP_050299843.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_050310184.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"