Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_014099754.1 6 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105;Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-2046106 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"alpha-linolenic acid (ALA) metabolism" XP_014102312.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014089050.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014102820.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014097321.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_014098083.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014085456.1 29 Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression" XP_014095569.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_014098752.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_014096195.1 13 Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216 "ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Collagen degradation";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Extracellular matrix organization";"Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Collagen chain trimerization" XP_014102184.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014103113.1 11 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695 "HATs acetylate histones";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events" XP_014090265.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_014099102.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_014092935.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_014098945.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_014088010.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091409.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_014095903.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_014089627.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_014103185.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014098552.1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_014086895.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014088744.1 11 KEGG: 00561+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053 "Glycerolipid metabolism";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II" XP_014093095.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_014101346.1 9 KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00130+2.6.1.5;Reactome: R-HSA-8963684 "Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tyrosine catabolism" XP_014091455.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_014090284.1 7 Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;MetaCyc: PWY-6368;Reactome: R-HSA-1855204 "Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol" XP_014088084.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690 "SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events" XP_014102713.1 4 MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50 "Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_014091436.1 20 KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288 "alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_014088880.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014093802.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014092772.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014086393.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014093297.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014093036.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_014091523.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_014095867.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014098528.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014089084.1 17 Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-75035;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601 "TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human cytomegalovirus infection";"Thermogenesis";"Transcriptional Regulation by E2F6";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" XP_014088539.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681 "Protein ubiquitination";"Degradation of AXIN";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT" XP_014090124.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" XP_014102080.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014091992.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_014103410.1 10 Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483 "Carnitine metabolism";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs" XP_014097773.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8856828 "LDL clearance";"Regulation of TLR by endogenous ligand";"VLDL assembly";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron remodeling";"Retinoid metabolism and transport";"LDL remodeling";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis" XP_014087372.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014102073.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014098718.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014096364.1 8 MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_014096434.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_014101883.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_014098268.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014099861.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_014096741.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014097343.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-3801;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9 "Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism" XP_014100311.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014093889.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014086194.1 3 Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation" XP_014086707.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_014092531.1 12 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-6796648 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes" XP_014096845.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation" XP_014090898.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014087557.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_014089423.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_014087121.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014093942.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014085917.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098761.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014102186.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014103151.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_014097041.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086071.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014090817.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-196780 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism" XP_014090819.1 9 KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599 "Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency" XP_014099142.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_014086637.1 2 Reactome: R-HSA-111458;Reactome: R-HSA-9627069 "Formation of apoptosome";"Regulation of the apoptosome activity" XP_014095267.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_014088632.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_014085569.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_014092464.1 52 Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-73863;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-167243 "Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Termination";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery" XP_014101394.1 17 KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-6969 "Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_014094996.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014089931.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014089686.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_014094398.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014098084.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014090460.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199 "Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation" XP_014088746.1 11 MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;MetaCyc: PWY-8052;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4 "Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism" XP_014093614.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_014100273.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014096604.1 7 KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Lysine catabolism";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation" XP_014103216.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014096970.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_014088209.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014093890.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014091705.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_014098276.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_014098898.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014097216.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014091135.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014089555.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098448.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014092149.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014087838.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752 "AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated" XP_014099419.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_014102774.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_014097834.1 4 MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_014091772.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014098240.1 12 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-5250924;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014093899.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_014095451.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_014091495.1 6 MetaCyc: PWY-7900;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis" XP_014103164.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_014094473.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014098340.1 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014086683.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_014090675.1 12 MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5857;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_014092228.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014095516.1 25 Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-381771;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-392451 "Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G beta:gamma signalling through PI3Kgamma" XP_014089100.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014100027.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014095768.1 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_014094803.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014093097.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_014093705.1 14 MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6728;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-3781 "TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)" XP_014099966.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014095523.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014087748.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_014095488.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_014101386.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014092459.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_014095855.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014092130.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014100519.1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_014097128.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092412.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-171306;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-2559582;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236 "Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"Packaging Of Telomere Ends";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination";"HCMV Late Events";"PKMTs methylate histone lysines";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_014089634.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014092692.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery" XP_014086644.1 3 Reactome: R-HSA-5635838;Reactome: R-HSA-525793;Reactome: R-HSA-5632681 "Activation of SMO";"Myogenesis";"Ligand-receptor interactions" XP_014101393.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014091305.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_014089095.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014101891.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014087687.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_014094096.1 10 KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001 "Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_014099462.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014102076.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_014095904.1 2 MetaCyc: PWY-6938;Reactome: R-HSA-430039 "NADH repair";"mRNA decay by 5' to 3' exoribonuclease" XP_014087970.1 15 Reactome: R-HSA-111465;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358749 "Apoptotic cleavage of cellular proteins";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated" XP_014100411.1 3 KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096;Reactome: R-HSA-2206282 "Glycosaminoglycan degradation";"HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B" XP_014086232.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_014099550.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_014097719.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin" XP_014098225.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_014091990.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987;Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_014098053.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921 "Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation" XP_014088653.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014086296.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014096905.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014098938.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_014096205.1 30 Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-983168;Reactome: R-HSA-2644607;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2644606 "Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014088392.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014102139.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014089932.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014092691.1 15 Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-176034 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Interactions of Tat with host cellular proteins" XP_014093335.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014095496.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex" XP_014095403.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014092265.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_014093854.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014092386.1 6 KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_014086771.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014097659.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091 "Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells" XP_014100452.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_014093284.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_014101184.1 7 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis" XP_014103528.1 19 MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7176;Reactome: R-HSA-380320;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis" XP_014102969.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phytate degradation I";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_014089685.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_014103627.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_014102064.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_014088194.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_014100060.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014088662.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014093165.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" XP_014087239.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014090293.1 8 Reactome: R-HSA-163754;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014090150.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014102281.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014102274.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_014096791.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014085485.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production" XP_014097388.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13 "Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism" XP_014095359.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_014089150.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014096119.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014093946.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014099467.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_014099398.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014100346.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism" XP_014096044.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_014092984.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014088606.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014102550.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" XP_014089393.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_014085184.1 11 MetaCyc: PWY-6606;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6596;MetaCyc: PWY-5381;MetaCyc: PWY-6608;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7821 "Guanosine nucleotides degradation II";"Nicotinate and nicotinamide metabolism";"UTP and CTP dephosphorylation I";"Purine metabolism";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Tunicamycin biosynthesis" XP_014098864.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014088496.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014103690.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_014100843.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" XP_014100288.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014090844.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_014094540.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_014086594.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_014086440.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085501.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events" XP_014085338.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014089870.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014087024.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_014098220.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_014092008.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014085637.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014099133.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_014102950.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014098591.1 10 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_014102473.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014093211.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014102759.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014087175.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_014088883.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation" XP_014093672.1 30 Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-167172 "RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome" XP_014088297.1 6 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3" XP_014088745.1 11 KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8055 "Sphingolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_014095803.1 11 Reactome: R-HSA-428890;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565 "Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_014099096.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_014091816.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014094033.1 24 Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-392170 "G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12" XP_014089237.1 6 Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73930 "Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_014101439.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014100632.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014093096.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_014093636.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014095644.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014094729.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014090761.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_014098245.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_014103106.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_014098070.1 32 Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167287;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-75953 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation" XP_014085213.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-426486 "Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis" XP_014095920.1 11 Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692 "EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR" XP_014100026.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_014098013.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_014095230.1 8 Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5083629 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_014089241.1 17 Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939;Reactome: R-HSA-1834949;Reactome: R-HSA-5693548 "HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Sensing of DNA Double Strand Breaks" XP_014094396.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465 "Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins" XP_014092618.1 3 KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate" XP_014087828.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014094664.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_014088100.1 5 Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88 "Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism" XP_014100691.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014089635.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014095906.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014086437.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_014095380.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014093461.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014085255.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_014094617.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_014103730.1 7 Reactome: R-HSA-5578999;MetaCyc: PWY-6840;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" XP_014099373.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091039.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014088105.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014091458.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014094609.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_014096977.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_014088402.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168 "Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014094662.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014101952.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_014093557.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014096068.1 8 Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Activation of RAC1";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_014091674.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014089577.1 18 MetaCyc: PWY-5913;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Arginine and proline metabolism" XP_014097782.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_014102319.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014090886.1 10 MetaCyc: PWY-5022;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19 "4-aminobutanoate degradation V";"L-glutamate degradation IV";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Propanoate metabolism";"4-aminobutanoate degradation I";"Degradation of GABA";"beta-Alanine metabolism" XP_014097431.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014099387.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014095743.1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism" XP_014086786.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_014085161.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014091570.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions" XP_014101670.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" XP_014091049.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098598.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014092271.1 17 Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;Reactome: R-HSA-3371599;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2 "Carnitine metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Propanoate metabolism" XP_014095602.1 5 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014087164.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" XP_014103581.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014102381.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092550.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014086676.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_014093709.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014095742.1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II" XP_014087600.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014086605.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014093845.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014100119.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_014088124.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919 "Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation";"Crosslinking of collagen fibrils" XP_014091726.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_014100978.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_014101085.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014097133.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014098384.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_014085719.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014091521.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300 "Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors" XP_014088401.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-179409 "APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A" XP_014095758.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014087331.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014097315.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_014099210.1 6 KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433 "Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation" XP_014091763.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014100679.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_014091955.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_014097036.1 58 Reactome: R-HSA-77305;MetaCyc: PWY-7007;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6944;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7779;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00930+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00380+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-77285;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77288;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6883;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77310;KEGG: 00410+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17;MetaCyc: PWY-5177;MetaCyc: PWY-1361;Reactome: R-HSA-1482798;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;Reactome: R-HSA-77346;MetaCyc: PWY-6863;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-6435;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946 "Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Methyl ketone biosynthesis (engineered)";"Lysine degradation";"Androstenedione degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Methyl tert-butyl ether degradation";"Phenylalanine metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Fatty acid salvage";"Caprolactam degradation";"Lysine degradation";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Tryptophan metabolism";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Benzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Benzoate degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid elongation";"Pyruvate fermentation to butanol II (engineered)";"Carbon fixation pathways in prokaryotes";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid elongation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"Aminobenzoate degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"beta-Alanine metabolism";"Butanoate metabolism";"Geraniol degradation";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Acyl chain remodeling of CL";"Caprolactam degradation";"Pyruvate fermentation to butanol I";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Geraniol degradation";"Tryptophan metabolism";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)" XP_014092569.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_014092162.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014090170.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_014103445.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_014098016.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014096923.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014098055.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation" XP_014098871.1 6 Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731;Reactome: R-HSA-5654693;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700 "FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling" XP_014099693.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_014095400.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_014099141.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_014089209.1 7 KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;Reactome: R-HSA-73817 "Purine metabolism";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Purine ribonucleoside monophosphate biosynthesis" XP_014094313.1 5 Reactome: R-HSA-162699;Reactome: R-HSA-162710;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_014102512.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014087373.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014091534.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_014092624.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014100211.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_014093296.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014091738.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014093084.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014087813.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014103220.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation" XP_014090039.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014102604.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902 "SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity" XP_014095714.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014087045.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_014091525.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_014092033.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014094434.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014101262.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014095198.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_014094724.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014102220.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014102289.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014085644.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014098006.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_014087895.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014085366.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_014089128.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014085280.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014102048.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_014096986.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_014098939.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_014098207.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_014097189.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_014098707.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014096589.1 7 MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80 "Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism" XP_014091998.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_014095468.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014100382.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_014099535.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014101086.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014101697.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014099784.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014088655.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014099665.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014093219.1 22 Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014090524.1 4 KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_014098248.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014094343.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling" XP_014099768.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_014088338.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014094436.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_014097257.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_014092318.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093945.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_014094094.1 10 MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2 "Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism" XP_014094539.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014093403.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014098645.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014098554.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69052 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_014096588.1 7 MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841 "Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis" XP_014091851.1 182 Reactome: R-HSA-450302;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-72695;Reactome: R-HSA-69481;Reactome: R-HSA-975957;Reactome: R-HSA-3134975;Reactome: R-HSA-5693607;Reactome: R-HSA-9013973;Reactome: R-HSA-975163;Reactome: R-HSA-975956;Reactome: R-HSA-1358803;Reactome: R-HSA-445989;Reactome: R-HSA-8854050;Reactome: R-HSA-9633012;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5654727;Reactome: R-HSA-205043;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-9646399;Reactome: R-HSA-5675221;Reactome: R-HSA-5607761;Reactome: R-HSA-5689901;Reactome: R-HSA-917937;Reactome: R-HSA-917729;Reactome: R-HSA-977225;Reactome: R-HSA-2122947;Reactome: R-HSA-6807004;Reactome: R-HSA-1253288;Reactome: R-HSA-4608870;Reactome: R-HSA-2672351;Reactome: R-HSA-6804756;Reactome: R-HSA-209560;Reactome: R-HSA-1234176;Reactome: R-HSA-6781827;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-6782210;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-2559582;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-937039;Reactome: R-HSA-179409;Reactome: R-HSA-75815;Reactome: R-HSA-9604323;Reactome: R-HSA-5654726;Reactome: R-HSA-1799339;Reactome: R-HSA-5696397;Reactome: R-HSA-9637628;Reactome: R-HSA-156902;Reactome: R-HSA-69017;Reactome: R-HSA-2691232;Reactome: R-HSA-5610780;Reactome: R-HSA-2559585;Reactome: R-HSA-912631;Reactome: R-HSA-174084;Reactome: R-HSA-937072;Reactome: R-HSA-110314;Reactome: R-HSA-5689603;Reactome: R-HSA-2173796;Reactome: R-HSA-2173791;Reactome: R-HSA-2565942;Reactome: R-HSA-72706;Reactome: R-HSA-975110;Reactome: R-HSA-937041;Reactome: R-HSA-2173795;Reactome: R-HSA-8876493;Reactome: R-HSA-9613829;Reactome: R-HSA-8849469;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-9013507;Reactome: R-HSA-192823;Reactome: R-HSA-9615710;Reactome: R-HSA-5658442;Reactome: R-HSA-209543;Reactome: R-HSA-5678895;Reactome: R-HSA-201681;Reactome: R-HSA-901032;Reactome: R-HSA-168927;Reactome: R-HSA-72702;Reactome: R-HSA-174178;Reactome: R-HSA-156827;Reactome: R-HSA-5655862;Reactome: R-HSA-2408557;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-6791226;Reactome: R-HSA-5684264;Reactome: R-HSA-2467813;Reactome: R-HSA-5689896;Reactome: R-HSA-174154;Reactome: R-HSA-1236382;Reactome: R-HSA-174048;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-2979096;Reactome: R-HSA-983168;Reactome: R-HSA-72649;Reactome: R-HSA-5696400;Reactome: R-HSA-5689877;Reactome: R-HSA-68949;Reactome: R-HSA-168928;Reactome: R-HSA-3769402;Reactome: R-HSA-72764;Reactome: R-HSA-5357956;Reactome: R-HSA-9636383;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-1295596;Reactome: R-HSA-168638;Reactome: R-HSA-9033241;Reactome: R-HSA-349425;Reactome: R-HSA-5693565;Reactome: R-HSA-5205685;Reactome: R-HSA-5362768;Reactome: R-HSA-2122948;Reactome: R-HSA-5676590;Reactome: R-HSA-532668;Reactome: R-HSA-8863795;Reactome: R-HSA-174113;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-182971;Reactome: R-HSA-4641263;Reactome: R-HSA-174490;Reactome: R-HSA-1169408;Reactome: R-HSA-8875360;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-2173788;Reactome: R-HSA-936964;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-2894862;Reactome: R-HSA-8852276;Reactome: R-HSA-8856828;Reactome: R-HSA-162588;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-6783310;Reactome: R-HSA-8866652;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8866654;Reactome: R-HSA-5687128;Reactome: R-HSA-110312;Reactome: R-HSA-5675482;Reactome: R-HSA-6781823;Reactome: R-HSA-936440;Reactome: R-HSA-937042;Reactome: R-HSA-6804760;Reactome: R-HSA-5654732;Reactome: R-HSA-8856825;Reactome: R-HSA-8939902;Reactome: R-HSA-72689;Reactome: R-HSA-9645460;Reactome: R-HSA-5632684;Reactome: R-HSA-5656121;Reactome: R-HSA-69541;Reactome: R-HSA-9014325;Reactome: R-HSA-211733;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-450408 "activated TAK1 mediates p38 MAPK activation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Formation of the ternary complex, and subsequently, the 43S complex";"G2/M Checkpoints";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of innate immune responses to cytosolic DNA";"Processing of DNA double-strand break ends";"TICAM1-dependent activation of IRF3/IRF7";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Downregulation of ERBB2:ERBB3 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Negative regulation of FGFR2 signaling";"NRIF signals cell death from the nucleus";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Circadian Clock";"Aggrephagy";"Negative regulation of MAPK pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Metalloprotease DUBs";"Iron uptake and transport";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Amyloid fiber formation";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MET activity";"Downregulation of ERBB4 signaling";"Asymmetric localization of PCP proteins";"Stimuli-sensing channels";"Regulation of TP53 Activity through Phosphorylation";"NF-kB is activated and signals survival";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in TC-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"Senescence-Associated Secretory Phenotype (SASP)";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"IRAK1 recruits IKK complex";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin-dependent degradation of Cyclin D";"Negative regulation of NOTCH4 signaling";"Negative regulation of FGFR1 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Modulation by Mtb of host immune system";"Peptide chain elongation";"CDK-mediated phosphorylation and removal of Cdc6";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of GLI1 by the proteasome";"Oncogene Induced Senescence";"Regulation of signaling by CBL";"Autodegradation of Cdh1 by Cdh1:APC/C";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recognition of DNA damage by PCNA-containing replication complex";"UCH proteinases";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of PLK1 Activity at G2/M Transition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IKK complex recruitment mediated by RIP1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"InlA-mediated entry of Listeria monocytogenes into host cells";"Chaperone Mediated Autophagy";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Viral mRNA Translation";"Late endosomal microautophagy";"Regulation of RAS by GAPs";"p75NTR recruits signalling complexes";"Defective CFTR causes cystic fibrosis";"TCF dependent signaling in response to WNT";"ER Quality Control Compartment (ERQC)";"TICAM1, RIP1-mediated IKK complex recruitment";"Ribosomal scanning and start codon recognition";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translesion synthesis by POLK";"Selenocysteine synthesis";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"Major pathway of rRNA processing in the nucleolus and cytosol";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Separation of Sister Chromatids";"Ovarian tumor domain proteases";"APC/C:Cdc20 mediated degradation of Securin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Cyclin B";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Antigen processing: Ubiquitination & Proteasome degradation";"Translation initiation complex formation";"Dual Incision in GG-NER";"Josephin domain DUBs";"Orc1 removal from chromatin";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Deactivation of the beta-catenin transactivating complex";"Eukaryotic Translation Termination";"TNFR1-induced NFkappaB signaling pathway";"Prevention of phagosomal-lysosomal fusion";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Spry regulation of FGF signaling";"NOD1/2 Signaling Pathway";"Peroxisomal protein import";"Autodegradation of the E3 ubiquitin ligase COP1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pink/Parkin Mediated Mitophagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activated NOTCH1 Transmits Signal to the Nucleus";"NIK-->noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Downregulation of ERBB2 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"EGFR downregulation";"Regulation of FZD by ubiquitination";"Membrane binding and targetting of GAG proteins";"ISG15 antiviral mechanism";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Downregulation of TGF-beta receptor signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Clathrin-mediated endocytosis";"Budding and maturation of HIV virion";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Dual incision in TC-NER";"Glycogen synthesis";"Fanconi Anemia Pathway";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"E3 ubiquitin ligases ubiquitinate target proteins";"MAPK6/MAPK4 signaling";"Translesion synthesis by REV1";"Regulation of necroptotic cell death";"Formation of TC-NER Pre-Incision Complex";"Negative regulators of DDX58/IFIH1 signaling";"IRAK2 mediated activation of TAK1 complex";"Regulation of TP53 Activity through Methylation";"Negative regulation of FGFR3 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of RUNX2 expression and activity";"Formation of a pool of free 40S subunits";"Alpha-protein kinase 1 signaling pathway";"Hedgehog 'on' state";"Translesion synthesis by POLI";"Stabilization of p53";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_014093952.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014100657.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014088556.1 15 MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-5484 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)" XP_014097781.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_014091184.1 5 MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6 "UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine metabolism" XP_014087424.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_014094616.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_014103461.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_014093887.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014088882.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism" XP_014103404.1 1 Reactome: R-HSA-419771 "Opsins" XP_014093728.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014096853.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086261.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_014093795.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014093341.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014099205.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122 "Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014092370.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_014099319.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014086788.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_014097499.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_014087806.1 1 Reactome: R-HSA-419771 "Opsins" XP_014102136.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway" XP_014086593.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_014097937.1 7 MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-4984;Reactome: R-HSA-70635 "Putrescine biosynthesis III";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Canavanine degradation";"Urea cycle";"Urea cycle" XP_014096634.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014095252.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_014098767.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014096661.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014086975.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014090764.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014088730.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014099526.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014095369.1 5 KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_014095849.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014103507.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_014096372.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014086993.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014096338.1 25 Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148 "RHO GTPases Activate Formins";"Kinesins";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014089947.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014085253.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_014097938.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014094348.1 7 Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014092082.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014091042.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087672.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014096852.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014093688.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014090801.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014094392.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-416993 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors" XP_014098992.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014097965.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859 "tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly" XP_014087503.1 9 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796 "Rho GTPase cycle";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation" XP_014085736.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_014098342.1 6 KEGG: 00380+1.14.13.9;Reactome: R-HSA-71240;MetaCyc: PWY-5651;MetaCyc: PWY-7765;MetaCyc: PWY-7717;MetaCyc: PWY-6309 "Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_014088700.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014099676.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014090226.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_014097707.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_014095233.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_014085423.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014091909.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014092867.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_014085873.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751 "Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity" XP_014102586.1 13 MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_014102904.1 10 Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-7524 "PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)" XP_014090774.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_014097734.1 3 Reactome: R-HSA-8964046;Reactome: R-HSA-8866376;Reactome: R-HSA-8866427 "VLDL clearance";"Reelin signalling pathway";"VLDLR internalisation and degradation" XP_014085926.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014086288.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014103413.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209 "Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_014088856.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014096567.1 5 Reactome: R-HSA-75896;Reactome: R-HSA-9033500;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26 "Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism" XP_014089871.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014096430.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_014101619.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_014089573.1 18 MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7383 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"(R)-cysteate degradation";"Arginine and proline metabolism";"Sulfolactate degradation III";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_014099218.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_014086121.1 33 Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-69656;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-69202;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Cyclin A:Cdk2-associated events at S phase entry";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape" XP_014094130.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014097040.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014093885.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014090444.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014088964.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014095633.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014090120.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014085444.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014100841.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014102521.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014091727.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_014098447.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014085860.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014095333.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014103628.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014095923.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014087114.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_014091452.1 20 MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_014095328.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_014090152.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014085877.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_014098671.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095489.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276 "Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-mediated anterograde transport";"Kinesins";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_014094312.1 2 MetaCyc: PWY-5381;KEGG: 00760+2.7.1.173+2.7.1.22 "Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_014102903.1 10 KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00072+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922;MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7571 "Butanoate metabolism";"Terpenoid backbone biosynthesis";"Synthesis and degradation of ketone bodies";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Ferrichrome A biosynthesis" XP_014097946.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014091862.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014095285.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014095873.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086807.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014097885.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_014102233.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014089845.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014091192.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5655862 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK" XP_014101020.1 6 MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_014098919.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014090670.1 18 MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.1;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;MetaCyc: PWY-6611;MetaCyc: PWY-5532;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00983+2.4.2.3 "Arsenate detoxification I (mammalian)";"Purine metabolism";"Adenine and adenosine salvage III";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Drug metabolism - other enzymes" XP_014090805.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_014096556.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_014094798.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014101793.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_014097609.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014103434.1 26 Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025 "Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Kinesins";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation" XP_014087555.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_014089244.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014092997.1 27 Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-975957;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-8851708;Reactome: R-HSA-111367;Reactome: R-HSA-72187;Reactome: R-HSA-159227;Reactome: R-HSA-77595;Reactome: R-HSA-191859;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-159231;Reactome: R-HSA-6807505;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-975956;Reactome: R-HSA-167242 "RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Signaling by FGFR2 IIIa TM";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA 3'-end processing";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs";"snRNP Assembly";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA polymerase II transcribes snRNA genes";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_014088160.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_014089360.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_014100626.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_014097236.1 5 MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_014093120.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_014102655.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_014087351.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014087881.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014095244.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092801.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014096670.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014098702.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014091380.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_014092305.1 9 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68827 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex" XP_014088665.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014086314.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation" XP_014085962.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014090896.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_014092858.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_014102049.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_014098725.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014095766.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014103582.1 17 Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167287 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"T cell receptor signaling pathway";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery" XP_014100780.1 15 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_014086403.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097373.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014096322.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014087608.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014103098.1 4 Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer" XP_014096408.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089442.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_014100543.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014097042.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014087556.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014094140.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling" XP_014088918.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_014092765.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092582.1 9 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"mTOR signaling pathway" XP_014090074.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_014086143.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014100836.1 13 KEGG: 05170+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"MAPK6/MAPK4 signaling";"mTOR signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"EPHB-mediated forward signaling";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014090171.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_014091524.1 30 Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-5674400;Reactome: R-HSA-199418;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69656;Reactome: R-HSA-1257604;Reactome: R-HSA-9614399;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-1358803;Reactome: R-HSA-198323;Reactome: R-HSA-8948751;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-198693;Reactome: R-HSA-211163;Reactome: R-HSA-8941332;Reactome: R-HSA-389513;Reactome: R-HSA-6804758;Reactome: R-HSA-9634638;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Regulation of TP53 Activity through Association with Co-factors";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"Constitutive Signaling by AKT1 E17K in Cancer";"Negative regulation of the PI3K/AKT network";"Human cytomegalovirus infection";"Cyclin A:Cdk2-associated events at S phase entry";"PIP3 activates AKT signaling";"Regulation of localization of FOXO transcription factors";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Downregulation of ERBB2:ERBB3 signaling";"AKT phosphorylates targets in the cytosol";"Regulation of PTEN stability and activity";"PI3K-Akt signaling pathway";"Cyclin E associated events during G1/S transition";"AKT phosphorylates targets in the nucleus";"AKT-mediated inactivation of FOXO1A";"RUNX2 regulates genes involved in cell migration";"CTLA4 inhibitory signaling";"Regulation of TP53 Activity through Acetylation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"mTOR signaling pathway" XP_014090121.1 10 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9648895 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency" XP_014094013.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014100834.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_014097637.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660 "Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway" XP_014093729.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014089827.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_014095781.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014096916.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Photosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling" XP_014094125.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" XP_014098199.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014086688.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-68962 "Dual Incision in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex" XP_014093596.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression" XP_014097451.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014102437.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014089132.1 6 MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-7442;Reactome: R-HSA-1474151 "Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_014094646.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087639.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_014099891.1 11 MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-6992;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-882;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_014098937.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055 "Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_014100223.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014094031.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014093594.1 16 Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723 "Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation" XP_014098109.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-2221 "Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_014103237.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_014099279.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_014103626.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014098022.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_014096518.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_014098446.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014095370.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014098789.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_014094867.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014085472.1 29 Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression" XP_014103597.1 6 MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism" XP_014098005.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_014094643.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_014095577.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_014093256.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_014093565.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014091385.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014095582.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_014096465.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014089189.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_014087738.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_014090507.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014101756.1 9 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD" XP_014085365.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_014098793.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_014095911.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014094090.1 10 KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-8001 "Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_014101548.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014095853.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159231 "NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_014085854.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_014090674.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5871;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872 "Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_014093770.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014099074.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_014101691.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014094735.1 14 MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_014096186.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014088942.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5744;Reactome: R-HSA-1475029 "Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide" XP_014090115.1 5 MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7 "Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiamine metabolism" XP_014091366.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014098648.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014092996.1 18 Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"mTORC1-mediated signalling";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014090287.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014087312.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014089424.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_014098894.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014085772.1 40 Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76042 "Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014090985.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_014096523.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014095986.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629 "ECM proteoglycans";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_014092570.1 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling" XP_014086812.1 3 Reactome: R-HSA-5619078;Reactome: R-HSA-727802;Reactome: R-HSA-6787639 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"Transport of nucleotide sugars";"GDP-fucose biosynthesis" XP_014086080.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_014095288.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_014089610.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014098263.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_014103290.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)" XP_014092885.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_014098673.1 24 Reactome: R-HSA-5610783;Reactome: R-HSA-442720;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-5610785;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-5610780;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-4420097;Reactome: R-HSA-432040;Reactome: R-HSA-8963896;Reactome: R-HSA-111931;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-8853659;Reactome: R-HSA-9634600;Reactome: R-HSA-422356 "Degradation of GLI2 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"GLI3 is processed to GLI3R by the proteasome";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"Degradation of GLI1 by the proteasome";"DARPP-32 events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"HDL assembly";"PKA-mediated phosphorylation of CREB";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Triglyceride catabolism";"Rap1 signalling";"RET signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion" XP_014086592.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-196025 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions" XP_014101083.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014096112.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_014095382.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014092389.1 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism" XP_014096828.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014094302.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_014102757.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014086883.1 12 MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5856 "Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_014094240.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014087169.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014090302.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014085706.1 23 Reactome: R-HSA-392170;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-9009391;Reactome: R-HSA-416482 "ADP signalling through P2Y purinoceptor 12";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events" XP_014099246.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_014099198.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381042 "Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression" XP_014099376.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014099674.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_014098597.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014101927.1 6 MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7790;Reactome: R-HSA-500753 "UMP biosynthesis III";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine biosynthesis" XP_014101051.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_014094102.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014085711.1 23 Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-416482 "Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events" XP_014103186.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_014093437.1 7 KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;MetaCyc: PWY-7807;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-7805;MetaCyc: PWY-6610 "Purine metabolism";"Adenine and adenosine salvage II";"Glyphosate degradation III";"Purine salvage";"Neutrophil degranulation";"(aminomethyl)phosphonate degradation";"Adenine salvage" XP_014093638.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014088322.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014091460.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014102244.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_014102151.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014090203.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_014085492.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092790.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014099197.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183 "Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes" XP_014086436.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_014087366.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014091139.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-422356 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Ion homeostasis";"DAG and IP3 signaling";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion" XP_014099358.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2024096;Reactome: R-HSA-2206296 "CS/DS degradation";"HS-GAG degradation";"MPS II - Hunter syndrome" XP_014096089.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_014099508.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014085570.1 4 KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_014085104.1 9 Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_014100512.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_014088881.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014089826.1 5 KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3 "Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" XP_014086802.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014103787.1 14 MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105 "Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport" XP_014092072.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_014098524.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014090732.1 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_014100711.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092600.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014087994.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_014092019.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014097081.1 4 MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_014102460.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_014091198.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-3249367 "STING mediated induction of host immune responses";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines" XP_014087566.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_014099434.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014103062.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014087826.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_014092811.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014086081.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_014100059.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_014098056.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471 "VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_014097433.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014091823.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014092367.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014097671.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014093082.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_014093937.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014094101.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014085238.1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER" XP_014100344.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism" XP_014088210.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014089081.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_014099858.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_014095470.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-168325 "SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis" XP_014092883.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014093954.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" XP_014097253.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014096516.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_014099716.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_014102213.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014101757.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014093441.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_014085430.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014099326.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014090967.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014095283.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014088075.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014086942.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014094585.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014094131.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014087044.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014099899.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5685939;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5696400 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"HDR through MMEJ (alt-NHEJ)";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER" XP_014096141.1 11 KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-5913;MetaCyc: PWY-7124 "Citrate cycle (TCA cycle)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Ethylene biosynthesis V (engineered)" XP_014099274.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_014102280.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014094118.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093835.1 34 Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-9639288;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-9610379 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Amino acids regulate mTORC1";"RHO GTPases Activate Formins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"HCMV Late Events" XP_014095908.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014091538.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014087621.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014102907.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_014085813.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_014085511.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_014090185.1 13 Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-561 "Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_014097838.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_014096108.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_014102721.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_014087059.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_014103163.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014088947.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014086562.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014086327.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014101408.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014101179.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_014094327.1 5 MetaCyc: PWY-6289;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7 "Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis" XP_014097138.1 29 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693571 "Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Stabilization of p53";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"mTOR signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Nonhomologous End-Joining (NHEJ)" XP_014087839.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221 "T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway" XP_014093307.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014089102.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014096166.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_014102485.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014097140.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_014085727.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014098265.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_014085428.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_014099048.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014090759.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_014088617.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014085493.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-163615 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation" XP_014097306.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014085680.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_014094739.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_014098088.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014090222.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_014092237.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_014094715.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014103578.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_014088184.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism" XP_014097151.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014094082.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014097332.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014090269.1 5 MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis" XP_014090343.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_014088558.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_014091679.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" XP_014086565.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014100625.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014085879.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541 "Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway" XP_014096380.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_014103541.1 12 MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-801;MetaCyc: PWY-6309;Reactome: R-HSA-71240;MetaCyc: PWY-2821;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-601;MetaCyc: PWY-1187 "Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism";"Glucosinolate biosynthesis from phenylalanine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine" XP_014085824.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014089472.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_014099974.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014089434.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_014091330.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014095059.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014102525.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014093218.1 22 Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749 "Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated" XP_014095559.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014086079.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_014088919.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_014095476.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_014101684.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014093349.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_014087307.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014094599.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096 "Keratan sulfate degradation";"Neutrophil degranulation";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_014092202.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014089800.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-6453 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis" XP_014100664.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014096397.1 20 MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7726 "Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_014089990.1 8 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;Reactome: R-HSA-6798695 "Purine salvage";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Surfactant metabolism";"Adenine and adenosine salvage V";"Neutrophil degranulation" XP_014097591.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_014090307.1 10 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription" XP_014090726.1 44 Reactome: R-HSA-170968;Reactome: R-HSA-8943724;Reactome: R-HSA-1295596;Reactome: R-HSA-5673001;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-879415;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5654727;Reactome: R-HSA-5674499;Reactome: R-HSA-5674135;Reactome: R-HSA-202670;Reactome: R-HSA-9649948;Reactome: R-HSA-3371453;Reactome: R-HSA-5668599;Reactome: R-HSA-5654732;Reactome: R-HSA-6802948;Reactome: R-HSA-5663213;Reactome: R-HSA-982772;Reactome: R-HSA-198753;Reactome: R-HSA-2029482;Reactome: R-HSA-9635465;Reactome: R-HSA-375165;Reactome: R-HSA-444257;Reactome: R-HSA-162658;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-881907;Reactome: R-HSA-456926;Reactome: R-HSA-445144;Reactome: R-HSA-2559580;Reactome: R-HSA-9634638;Reactome: R-HSA-9627069;Reactome: R-HSA-2559582;Reactome: R-HSA-6802955;Reactome: R-HSA-8939211;Reactome: R-HSA-8940973;Reactome: R-HSA-5654726;Reactome: R-HSA-74749;Reactome: R-HSA-5654733;Reactome: R-HSA-112409;Reactome: R-HSA-6811558;Reactome: R-HSA-2559585;Reactome: R-HSA-6802952 "Frs2-mediated activation";"Regulation of PTEN gene transcription";"Spry regulation of FGF signaling";"RAF/MAP kinase cascade";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Advanced glycosylation endproduct receptor signaling";"mTOR signaling pathway";"Negative regulation of FGFR2 signaling";"Negative feedback regulation of MAPK pathway";"MAP2K and MAPK activation";"ERKs are inactivated";"Signaling downstream of RAS mutants";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate NADPH Oxidases";"Negative regulation of FGFR3 signaling";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"Growth hormone receptor signaling";"ERK/MAPK targets";"Regulation of actin dynamics for phagocytic cup formation";"Suppression of apoptosis";"NCAM signaling for neurite out-growth";"RSK activation";"Golgi Cisternae Pericentriolar Stack Reorganization";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Gastrin-CREB signalling pathway via PKC and MAPK";"Thrombin signalling through proteinase activated receptors (PARs)";"Signal transduction by L1";"Oxidative Stress Induced Senescence";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of the apoptosome activity";"Senescence-Associated Secretory Phenotype (SASP)";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ESR-mediated signaling";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR1 signaling";"Signal attenuation";"Negative regulation of FGFR4 signaling";"RAF-independent MAPK1/3 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Oncogene Induced Senescence";"Signaling by BRAF and RAF fusions" XP_014100455.1 33 Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-159227 "snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA" XP_014094393.1 6 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-416993 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors" XP_014092342.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014096425.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747 "Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization" XP_014090392.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_014095815.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014090221.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014086004.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_014097333.1 14 MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876 "Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_014088846.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014097982.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" XP_014094672.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_014096483.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897 "Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes" XP_014098788.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;Reactome: R-HSA-73621 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism" XP_014098796.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014089902.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_014092050.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_014086747.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_014085270.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014089844.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014102993.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014094344.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014088221.1 10 KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11 "Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism" XP_014094481.1 15 Reactome: R-HSA-9665247;Reactome: R-HSA-9665249;Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565;Reactome: R-HSA-9665245;Reactome: R-HSA-1227986;Reactome: R-HSA-9634285;Reactome: R-HSA-5637810;Reactome: R-HSA-9665233;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251 "Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to afatinib";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to trastuzumab";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib" XP_014101030.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014096995.1 1 Reactome: R-HSA-3000178 "ECM proteoglycans" XP_014095483.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA" XP_014088543.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014085610.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014098010.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014096188.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Activation of SMO" XP_014087135.1 8 Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-165054 "Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA" XP_014102375.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_014095520.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_014092908.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014103667.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014099968.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_014094877.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_014095006.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014099455.1 10 KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"HS-GAG degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_014098160.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014091743.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014099677.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014093742.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7177 "Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II" XP_014096793.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014089219.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_014088312.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014091522.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_014101089.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014091852.1 182 Reactome: R-HSA-2173796;Reactome: R-HSA-5689603;Reactome: R-HSA-2565942;Reactome: R-HSA-2173791;Reactome: R-HSA-72706;Reactome: R-HSA-975110;Reactome: R-HSA-937041;Reactome: R-HSA-2173795;Reactome: R-HSA-9613829;Reactome: R-HSA-8876493;Reactome: R-HSA-8849469;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-9013507;Reactome: R-HSA-192823;Reactome: R-HSA-5658442;Reactome: R-HSA-9615710;Reactome: R-HSA-209543;Reactome: R-HSA-5678895;Reactome: R-HSA-201681;Reactome: R-HSA-901032;Reactome: R-HSA-168927;Reactome: R-HSA-72702;Reactome: R-HSA-174178;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-5655862;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-6781827;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-6782210;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-2559582;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-937039;Reactome: R-HSA-75815;Reactome: R-HSA-179409;Reactome: R-HSA-5654726;Reactome: R-HSA-9604323;Reactome: R-HSA-1799339;Reactome: R-HSA-5696397;Reactome: R-HSA-156902;Reactome: R-HSA-69017;Reactome: R-HSA-9637628;Reactome: R-HSA-2691232;Reactome: R-HSA-2559585;Reactome: R-HSA-5610780;Reactome: R-HSA-912631;Reactome: R-HSA-174084;Reactome: R-HSA-110314;Reactome: R-HSA-937072;Reactome: R-HSA-8854050;Reactome: R-HSA-9633012;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5654727;Reactome: R-HSA-205043;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-9646399;Reactome: R-HSA-5675221;Reactome: R-HSA-5607761;Reactome: R-HSA-5689901;Reactome: R-HSA-917937;Reactome: R-HSA-917729;Reactome: R-HSA-977225;Reactome: R-HSA-2122947;Reactome: R-HSA-6807004;Reactome: R-HSA-1253288;Reactome: R-HSA-4608870;Reactome: R-HSA-2672351;Reactome: R-HSA-6804756;Reactome: R-HSA-209560;Reactome: R-HSA-450302;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-69481;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-3134975;Reactome: R-HSA-5693607;Reactome: R-HSA-9013973;Reactome: R-HSA-975163;Reactome: R-HSA-975956;Reactome: R-HSA-1358803;Reactome: R-HSA-445989;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-8866652;Reactome: R-HSA-6783310;Reactome: R-HSA-9020702;Reactome: R-HSA-110312;Reactome: R-HSA-5687128;Reactome: R-HSA-8866654;Reactome: R-HSA-1169091;Reactome: R-HSA-5675482;Reactome: R-HSA-6781823;Reactome: R-HSA-936440;Reactome: R-HSA-937042;Reactome: R-HSA-6804760;Reactome: R-HSA-8856825;Reactome: R-HSA-5654732;Reactome: R-HSA-8939902;Reactome: R-HSA-72689;Reactome: R-HSA-5656121;Reactome: R-HSA-5632684;Reactome: R-HSA-9645460;Reactome: R-HSA-69541;Reactome: R-HSA-9014325;Reactome: R-HSA-211733;Reactome: R-HSA-2644606;Reactome: R-HSA-6804757;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-8875360;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-2173788;Reactome: R-HSA-936964;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-2894862;Reactome: R-HSA-8852276;Reactome: R-HSA-162588;Reactome: R-HSA-8856828;Reactome: R-HSA-4641257;Reactome: R-HSA-5357956;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-9636383;Reactome: R-HSA-1295596;Reactome: R-HSA-168638;Reactome: R-HSA-9033241;Reactome: R-HSA-349425;Reactome: R-HSA-5693565;Reactome: R-HSA-5205685;Reactome: R-HSA-5362768;Reactome: R-HSA-2122948;Reactome: R-HSA-5676590;Reactome: R-HSA-8863795;Reactome: R-HSA-532668;Reactome: R-HSA-174113;Reactome: R-HSA-3785653;Reactome: R-HSA-175474;Reactome: R-HSA-182971;Reactome: R-HSA-4641263;Reactome: R-HSA-174490;Reactome: R-HSA-382556;Reactome: R-HSA-6791226;Reactome: R-HSA-5684264;Reactome: R-HSA-2467813;Reactome: R-HSA-5689896;Reactome: R-HSA-174154;Reactome: R-HSA-1236382;Reactome: R-HSA-174048;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-8948747;Reactome: R-HSA-180534;Reactome: R-HSA-2979096;Reactome: R-HSA-983168;Reactome: R-HSA-72649;Reactome: R-HSA-5696400;Reactome: R-HSA-5689877;Reactome: R-HSA-68949;Reactome: R-HSA-168928;Reactome: R-HSA-72764;Reactome: R-HSA-3769402 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"UCH proteinases";"Regulation of PLK1 Activity at G2/M Transition";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IKK complex recruitment mediated by RIP1";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Chaperone Mediated Autophagy";"InlA-mediated entry of Listeria monocytogenes into host cells";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Viral mRNA Translation";"Regulation of RAS by GAPs";"Late endosomal microautophagy";"p75NTR recruits signalling complexes";"Defective CFTR causes cystic fibrosis";"TCF dependent signaling in response to WNT";"ER Quality Control Compartment (ERQC)";"TICAM1, RIP1-mediated IKK complex recruitment";"Ribosomal scanning and start codon recognition";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translesion synthesis by POLK";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in TC-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"Senescence-Associated Secretory Phenotype (SASP)";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"IRAK1 recruits IKK complex";"Ubiquitin-dependent degradation of Cyclin D";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulation of FGFR1 signaling";"Negative regulation of NOTCH4 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Peptide chain elongation";"CDK-mediated phosphorylation and removal of Cdc6";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Oncogene Induced Senescence";"Degradation of GLI1 by the proteasome";"Regulation of signaling by CBL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Recognition of DNA damage by PCNA-containing replication complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Negative regulation of FGFR2 signaling";"NRIF signals cell death from the nucleus";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Circadian Clock";"Aggrephagy";"Negative regulation of MAPK pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Metalloprotease DUBs";"Iron uptake and transport";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Amyloid fiber formation";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MET activity";"Downregulation of ERBB4 signaling";"Asymmetric localization of PCP proteins";"Stimuli-sensing channels";"Regulation of TP53 Activity through Phosphorylation";"NF-kB is activated and signals survival";"activated TAK1 mediates p38 MAPK activation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"G2/M Checkpoints";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of innate immune responses to cytosolic DNA";"Processing of DNA double-strand break ends";"TICAM1-dependent activation of IRF3/IRF7";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Downregulation of ERBB2:ERBB3 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Dual incision in TC-NER";"Glycogen synthesis";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Fanconi Anemia Pathway";"Interleukin-1 signaling";"Translesion synthesis by REV1";"MAPK6/MAPK4 signaling";"E3 ubiquitin ligases ubiquitinate target proteins";"Activation of NF-kappaB in B cells";"Regulation of necroptotic cell death";"Formation of TC-NER Pre-Incision Complex";"Negative regulators of DDX58/IFIH1 signaling";"IRAK2 mediated activation of TAK1 complex";"Regulation of TP53 Activity through Methylation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Regulation of RUNX2 expression and activity";"Formation of a pool of free 40S subunits";"Translesion synthesis by POLI";"Hedgehog 'on' state";"Alpha-protein kinase 1 signaling pathway";"Stabilization of p53";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of TP53 Degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Downregulation of TGF-beta receptor signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Budding and maturation of HIV virion";"Clathrin-mediated endocytosis";"Degradation of AXIN";"TNFR1-induced NFkappaB signaling pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Prevention of phagosomal-lysosomal fusion";"Spry regulation of FGF signaling";"NOD1/2 Signaling Pathway";"Peroxisomal protein import";"Autodegradation of the E3 ubiquitin ligase COP1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pink/Parkin Mediated Mitophagy";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activated NOTCH1 Transmits Signal to the Nucleus";"NIK-->noncanonical NF-kB signaling";"Downregulation of ERBB2 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SCF-beta-TrCP mediated degradation of Emi1";"Myoclonic epilepsy of Lafora";"Assembly Of The HIV Virion";"EGFR downregulation";"Regulation of FZD by ubiquitination";"Membrane binding and targetting of GAG proteins";"ABC-family proteins mediated transport";"Major pathway of rRNA processing in the nucleolus and cytosol";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Separation of Sister Chromatids";"Ovarian tumor domain proteases";"APC/C:Cdc20 mediated degradation of Securin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Cyclin B";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN localization";"Vpu mediated degradation of CD4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Antigen processing: Ubiquitination & Proteasome degradation";"Translation initiation complex formation";"Dual Incision in GG-NER";"Josephin domain DUBs";"Orc1 removal from chromatin";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Eukaryotic Translation Termination";"Deactivation of the beta-catenin transactivating complex" XP_014090522.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" XP_014092317.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014085737.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014091158.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014095670.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014100655.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_014088996.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014093388.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014091715.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_014099592.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_014092819.1 5 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014092029.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_014102267.1 13 MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410 "Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis" XP_014091976.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_014102533.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_014089489.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014098571.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014098261.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_014103697.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_014094002.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014098430.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014097390.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014087369.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014095162.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014094329.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014098709.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014097490.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014092506.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014089542.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014095838.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_014088335.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014098486.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014096930.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014091787.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014095616.1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_014088030.1 8 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_014088769.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_014100209.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096560.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Synthesis of PA" XP_014100137.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014093552.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014095581.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" XP_014090695.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014103506.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_014092073.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" XP_014093099.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_014087785.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014086234.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_014097217.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014098635.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014094366.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_014092115.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014097595.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014095802.1 7 MetaCyc: PWY-7221;Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-3000170;Reactome: R-HSA-373753 "Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Syndecan interactions";"Nephrin family interactions" XP_014086626.1 3 MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757 "Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines" XP_014088593.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014097057.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014093848.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_014097056.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014091369.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014093009.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_014100004.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014092485.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948 "MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants" XP_014099834.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014095465.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095680.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014089127.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014095007.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA" XP_014095548.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_014087008.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport" XP_014086656.1 37 Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-983170;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-204005;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-2132295;Reactome: R-HSA-159231 "Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"HCMV Late Events";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"RHO GTPases Activate Formins";"HCMV Early Events";"COPII-mediated vesicle transport";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"MHC class II antigen presentation";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_014091928.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014095881.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_014101281.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014099194.1 4 Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_014093196.1 3 KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE" XP_014099738.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014096476.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576886 "Voltage gated Potassium channels";"Phase 4 - resting membrane potential" XP_014102719.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014089804.1 16 Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900 "Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"Gap junction degradation";"Formation of annular gap junctions";"VLDLR internalisation and degradation";"LDL clearance";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4" XP_014086607.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014092587.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014102781.1 16 Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-5602680 "DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR5)" XP_014098696.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_014095493.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014088859.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy" XP_014090473.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014096537.1 5 MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" XP_014097572.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014103505.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014097557.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014090164.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_014089720.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085363.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_014098003.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014091099.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014099214.1 6 MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation" XP_014088874.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_014085220.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014090196.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_014095330.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014087250.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014102963.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014096642.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_014092595.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_014100475.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25 "Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis" XP_014094777.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014087613.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014089023.1 18 Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7176;MetaCyc: PWY-7220 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_014093118.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014094686.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014098147.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_014091410.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_014097873.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014097311.1 4 KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_014087855.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_014088336.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014085858.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014089277.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_014100615.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014089997.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_014102374.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_014092877.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_014102212.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014092379.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-140875 "Cell surface interactions at the vascular wall";"Common Pathway of Fibrin Clot Formation" XP_014093921.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014093048.1 11 MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6538;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-5695;Reactome: R-HSA-8851680 "Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Theophylline degradation";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Caffeine degradation III (bacteria, via demethylation)";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions" XP_014088742.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014102412.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_014100712.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014088720.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_014088847.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014102518.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014086058.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_014090535.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014097059.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014086821.1 4 MetaCyc: PWY-7920;KEGG: 00510+3.2.1.114;KEGG: 00513+3.2.1.114;MetaCyc: PWY-7426 "Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_014086911.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_014096298.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014097757.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014102160.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_014101666.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_014097751.1 13 MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2161;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9 "Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes" XP_014097769.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_014102901.1 6 MetaCyc: PWY-7286;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion" XP_014102658.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_014101601.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Oxidative phosphorylation";"Ion channel transport";"Insulin receptor recycling" XP_014103769.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_014096885.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" XP_014102758.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014092584.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_014093390.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014093030.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014086973.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014088936.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation" XP_014085135.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014091238.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014096551.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_014088086.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014087716.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_014086331.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014096526.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014088995.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014098153.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_014099687.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014090881.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014088270.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014088101.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014087743.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_014096383.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" XP_014087364.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014091822.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014090458.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_014096308.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation" XP_014101153.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014089974.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014087489.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014098804.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014094281.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation" XP_014100703.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_014092150.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014093303.1 9 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-416476;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-8052;MetaCyc: PWY-6351 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_014086374.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_014090239.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_014091336.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_014087425.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_014103711.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014093355.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014095643.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014086523.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014087305.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014093029.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014100219.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_014102965.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_014099876.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_014088145.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_014095560.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014090180.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014087235.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_014096745.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_014102926.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014099180.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014102409.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014094663.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014093169.1 5 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_014098449.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014098227.1 6 KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6364 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" XP_014102825.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_014102449.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_014102424.1 12 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416 "Ether lipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_014091470.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-7852 "Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_014093348.1 3 MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6367 "3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_014091007.1 10 Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-2151201 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis" XP_014094036.1 7 Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174 "Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_014095975.1 5 MetaCyc: PWY-7761;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)" XP_014090579.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014088441.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014092605.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-7902 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis" XP_014102450.1 17 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Meiotic synapsis";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"mTOR signaling pathway";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway" XP_014088092.1 57 Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-532668;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-4641257 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN" XP_014087948.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014089558.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014085857.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014091673.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014101661.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014093711.1 14 KEGG: 00720+1.3.5.1;MetaCyc: PWY-6728;Reactome: R-HSA-611105;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1 "Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_014101884.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014089180.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082 "Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_014103131.1 4 Reactome: R-HSA-446199;Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_014093305.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014094849.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_014095394.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014085708.1 23 Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926 "G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)" XP_014090899.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014101511.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" XP_014086286.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_014095011.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_014093515.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014099506.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014086290.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_014099577.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_014085282.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014092216.1 6 KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;Reactome: R-HSA-1268020;KEGG: 00020+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Mitochondrial protein import";"Citrate cycle (TCA cycle)" XP_014086457.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014095280.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014102705.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_014094909.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" XP_014086954.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_014092240.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" XP_014092128.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014101792.1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" XP_014089930.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1" XP_014103595.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221 "Pentose phosphate pathway";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_014096047.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217 "Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine metabolism";"Purine salvage" XP_014102278.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014085927.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014095921.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802 "Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_014096601.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014094058.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014093792.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014102505.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_014086996.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014090657.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" XP_014094119.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014103256.1 179 Reactome: R-HSA-5205685;Reactome: R-HSA-5693565;Reactome: R-HSA-9033241;Reactome: R-HSA-349425;Reactome: R-HSA-9636383;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-1295596;Reactome: R-HSA-4641263;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2122948;Reactome: R-HSA-174113;Reactome: R-HSA-8863795;Reactome: R-HSA-532668;Reactome: R-HSA-1236382;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-5689896;Reactome: R-HSA-6791226;Reactome: R-HSA-5684264;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-3769402;Reactome: R-HSA-168928;Reactome: R-HSA-72764;Reactome: R-HSA-5696400;Reactome: R-HSA-5689877;Reactome: R-HSA-2979096;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-1169091;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-5687128;Reactome: R-HSA-936440;Reactome: R-HSA-6781823;Reactome: R-HSA-5675482;Reactome: R-HSA-9020702;Reactome: R-HSA-8866652;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-3322077;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-6804757;Reactome: R-HSA-2644606;Reactome: R-HSA-69541;Reactome: R-HSA-211733;Reactome: R-HSA-9014325;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5656121;Reactome: R-HSA-9645460;Reactome: R-HSA-72689;Reactome: R-HSA-937042;Reactome: R-HSA-5654732;Reactome: R-HSA-8856825;Reactome: R-HSA-6804760;Reactome: R-HSA-2173788;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169408;Reactome: R-HSA-8875360;Reactome: R-HSA-4641257;Reactome: R-HSA-162588;Reactome: R-HSA-8856828;Reactome: R-HSA-5656169;Reactome: R-HSA-8852276;Reactome: R-HSA-2894862;Reactome: R-HSA-936964;Reactome: R-HSA-5654733;Reactome: R-HSA-5675221;Reactome: R-HSA-205043;Reactome: R-HSA-5654727;Reactome: R-HSA-5610783;Reactome: R-HSA-9646399;Reactome: R-HSA-5358346;Reactome: R-HSA-400253;Reactome: R-HSA-5696394;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-8854050;Reactome: R-HSA-9633012;Reactome: R-HSA-209560;Reactome: R-HSA-2672351;Reactome: R-HSA-4608870;Reactome: R-HSA-6804756;Reactome: R-HSA-977225;Reactome: R-HSA-6807004;Reactome: R-HSA-1253288;Reactome: R-HSA-2122947;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-5689901;Reactome: R-HSA-917729;Reactome: R-HSA-5693607;Reactome: R-HSA-975957;Reactome: R-HSA-3134975;Reactome: R-HSA-69481;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-450302;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-975956;Reactome: R-HSA-445989;Reactome: R-HSA-1358803;Reactome: R-HSA-975163;Reactome: R-HSA-9013973;Reactome: R-HSA-192823;Reactome: R-HSA-9013507;Reactome: R-HSA-5658442;Reactome: R-HSA-9615710;Reactome: R-HSA-209543;Reactome: R-HSA-202424;Reactome: R-HSA-8849469;Reactome: R-HSA-9010553;Reactome: R-HSA-937041;Reactome: R-HSA-975110;Reactome: R-HSA-8876493;Reactome: R-HSA-9613829;Reactome: R-HSA-2173795;Reactome: R-HSA-2173791;Reactome: R-HSA-2173796;Reactome: R-HSA-2565942;Reactome: R-HSA-5689603;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-5655862;Reactome: R-HSA-2408557;Reactome: R-HSA-1236974;Reactome: R-HSA-168927;Reactome: R-HSA-901032;Reactome: R-HSA-5678895;Reactome: R-HSA-201681;Reactome: R-HSA-2559580;Reactome: R-HSA-5689880;Reactome: R-HSA-2559582;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-450321;Reactome: R-HSA-180585;Reactome: R-HSA-6782210;Reactome: R-HSA-5607764;Reactome: R-HSA-6781827;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-912631;Reactome: R-HSA-174084;Reactome: R-HSA-110314;Reactome: R-HSA-937072;Reactome: R-HSA-9637628;Reactome: R-HSA-156902;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-2559585;Reactome: R-HSA-2691232;Reactome: R-HSA-5696397;Reactome: R-HSA-1799339;Reactome: R-HSA-5654726;Reactome: R-HSA-9604323;Reactome: R-HSA-179409;Reactome: R-HSA-75815;Reactome: R-HSA-937039 "Pink/Parkin Mediated Mitophagy";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Peroxisomal protein import";"Autodegradation of the E3 ubiquitin ligase COP1";"Prevention of phagosomal-lysosomal fusion";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"Spry regulation of FGF signaling";"Regulation of FZD by ubiquitination";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activated NOTCH1 Transmits Signal to the Nucleus";"SCF-beta-TrCP mediated degradation of Emi1";"Downregulation of ERBB2 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Ovarian tumor domain proteases";"Major pathway of rRNA processing in the nucleolus and cytosol";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Deactivation of the beta-catenin transactivating complex";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Eukaryotic Translation Termination";"Dual Incision in GG-NER";"Josephin domain DUBs";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"Activation of NF-kappaB in B cells";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"MAPK6/MAPK4 signaling";"Negative regulators of DDX58/IFIH1 signaling";"Formation of TC-NER Pre-Incision Complex";"Regulation of necroptotic cell death";"Interleukin-1 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Neddylation";"Glycogen synthesis";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of TP53 Degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Stabilization of p53";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Translesion synthesis by POLI";"Alpha-protein kinase 1 signaling pathway";"Formation of a pool of free 40S subunits";"IRAK2 mediated activation of TAK1 complex";"Negative regulation of FGFR3 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of TP53 Activity through Methylation";"Downregulation of TGF-beta receptor signaling";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"ISG15 antiviral mechanism";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of AXIN";"Budding and maturation of HIV virion";"Clathrin-mediated endocytosis";"Termination of translesion DNA synthesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulation of FGFR4 signaling";"Negative regulation of MAPK pathway";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR2 signaling";"Degradation of GLI2 by the proteasome";"Aggrephagy";"Hedgehog ligand biogenesis";"Circadian Clock";"DNA Damage Recognition in GG-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"NF-kB is activated and signals survival";"Stimuli-sensing channels";"Asymmetric localization of PCP proteins";"Regulation of TP53 Activity through Phosphorylation";"Amyloid fiber formation";"Negative regulation of MET activity";"Downregulation of ERBB4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Metalloprotease DUBs";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Processing of DNA double-strand break ends";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of innate immune responses to cytosolic DNA";"G2/M Checkpoints";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"activated TAK1 mediates p38 MAPK activation";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Downregulation of ERBB2:ERBB3 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1-dependent activation of IRF3/IRF7";"Viral mRNA Translation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulation of RAS by GAPs";"Late endosomal microautophagy";"p75NTR recruits signalling complexes";"Downstream TCR signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of expression of SLITs and ROBOs";"IKK complex recruitment mediated by RIP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"Chaperone Mediated Autophagy";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of PLK1 Activity at G2/M Transition";"UCH proteinases";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Translesion synthesis by POLK";"Selenocysteine synthesis";"ER-Phagosome pathway";"TICAM1, RIP1-mediated IKK complex recruitment";"ER Quality Control Compartment (ERQC)";"Defective CFTR causes cystic fibrosis";"TCF dependent signaling in response to WNT";"Oxidative Stress Induced Senescence";"Ub-specific processing proteases";"Senescence-Associated Secretory Phenotype (SASP)";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in TC-NER";"CLEC7A (Dectin-1) signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Regulation of signaling by CBL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Recognition of DNA damage by PCNA-containing replication complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Modulation by Mtb of host immune system";"Peptide chain elongation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Oncogene Induced Senescence";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR1 signaling";"Negative regulation of NOTCH4 signaling";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin-dependent degradation of Cyclin D";"IRAK1 recruits IKK complex" XP_014094792.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_014101851.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014102082.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_014088588.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_014092761.1 24 Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-202424;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-6804757 "Activation of AKT2";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RSK activation";"Downstream TCR signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Integrin signaling";"Regulation of TP53 Degradation" XP_014103529.1 19 MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7224;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184 "UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_014102459.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014099353.1 4 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation";"Pyrophosphate hydrolysis" XP_014089125.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014091857.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014102221.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014100754.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014098224.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_014091865.1 4 Reactome: R-HSA-1855183;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism" XP_014097947.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014091243.1 5 Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-166208 "mTOR signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling" XP_014102043.1 5 KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00260+2.3.1.37;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Glycine, serine and threonine metabolism";"Heme biosynthesis" XP_014093422.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014090179.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014088368.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_014103154.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_014086531.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014103473.1 13 MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-5122;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-6383 "Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Geranyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_014097534.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014102970.1 17 KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;Reactome: R-HSA-6798695;Reactome: R-HSA-74259 "Purine metabolism";"Arsenate detoxification I (mammalian)";"Purine salvage";"Pyrimidine metabolism";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Neutrophil degranulation";"Purine catabolism" XP_014090438.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014098470.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014086326.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014099113.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014090773.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_014092844.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_014088608.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_014102277.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014085703.1 83 Reactome: R-HSA-9034864;Reactome: R-HSA-388841;Reactome: R-HSA-8875656;Reactome: R-HSA-1963642;Reactome: R-HSA-109704;Reactome: R-HSA-5654695;Reactome: R-HSA-2871809;Reactome: R-HSA-8851907;Reactome: R-HSA-5654693;Reactome: R-HSA-1433557;Reactome: R-HSA-9645135;Reactome: R-HSA-2219530;Reactome: R-HSA-9027284;Reactome: R-HSA-512988;Reactome: R-HSA-5654689;Reactome: R-HSA-5663213;Reactome: R-HSA-8853334;Reactome: R-HSA-9028731;Reactome: R-HSA-9634285;Reactome: R-HSA-389359;Reactome: R-HSA-8856825;Reactome: R-HSA-8983432;Reactome: R-HSA-5654732;Reactome: R-HSA-8865999;Reactome: R-HSA-375165;Reactome: R-HSA-5654699;Reactome: R-HSA-8853338;Reactome: R-HSA-8875360;Reactome: R-HSA-1839117;Reactome: R-HSA-2871796;Reactome: R-HSA-9607240;Reactome: R-HSA-5655253;Reactome: R-HSA-2428933;Reactome: R-HSA-180336;Reactome: R-HSA-912631;Reactome: R-HSA-8856828;Reactome: R-HSA-1250196;Reactome: R-HSA-5654726;Reactome: R-HSA-5654733;Reactome: R-HSA-1963640;Reactome: R-HSA-912526;Reactome: R-HSA-5654727;Reactome: R-HSA-391160;Reactome: R-HSA-186763;Reactome: R-HSA-5673001;Reactome: R-HSA-1295596;Reactome: R-HSA-2179392;Reactome: R-HSA-112412;Reactome: R-HSA-1250347;Reactome: R-HSA-5654720;Reactome: R-HSA-182971;Reactome: R-HSA-180292;Reactome: R-HSA-9026519;Reactome: R-HSA-74751;Reactome: R-HSA-2029482;Reactome: R-HSA-6807004;Reactome: R-HSA-8875555;Reactome: R-HSA-8853659;Reactome: R-HSA-5654688;Reactome: R-HSA-354194;Reactome: R-HSA-5654710;Reactome: R-HSA-5654719;Reactome: R-HSA-5655302;Reactome: R-HSA-8851805;Reactome: R-HSA-1236382;Reactome: R-HSA-167044;Reactome: R-HSA-983695;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700;Reactome: R-HSA-5654704;Reactome: R-HSA-5637810;Reactome: R-HSA-1433559;Reactome: R-HSA-6811558;Reactome: R-HSA-9028335;Reactome: R-HSA-1257604;Reactome: R-HSA-210993;Reactome: R-HSA-9664565;Reactome: R-HSA-5655291;Reactome: R-HSA-74749;Reactome: R-HSA-5654712;Reactome: R-HSA-179812;Reactome: R-HSA-2424491;Reactome: R-HSA-2730905 "Activated NTRK3 signals through RAS";"Costimulation by the CD28 family";"MET receptor recycling";"PI3K events in ERBB2 signaling";"PI3K Cascade";"PI-3K cascade:FGFR2";"FCERI mediated Ca+2 mobilization";"MET activates PI3K/AKT signaling";"FRS-mediated FGFR1 signaling";"Signaling by SCF-KIT";"STAT5 Activation";"Constitutive Signaling by Aberrant PI3K in Cancer";"Erythropoietin activates RAS";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI-3K cascade:FGFR1";"RHO GTPases Activate WASPs and WAVEs";"Signaling by FGFR3 fusions in cancer";"Activated NTRK2 signals through FRS2 and FRS3";"Constitutive Signaling by Overexpressed ERBB2";"CD28 dependent Vav1 pathway";"Cargo recognition for clathrin-mediated endocytosis";"Interleukin-15 signaling";"Negative regulation of FGFR3 signaling";"MET activates PTPN11";"NCAM signaling for neurite out-growth";"SHC-mediated cascade:FGFR2";"Signaling by FGFR3 point mutants in cancer";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signaling by cytosolic FGFR1 fusion mutants";"FCERI mediated MAPK activation";"FLT3 Signaling";"Signaling by FGFR2 in disease";"SHC-related events triggered by IGF1R";"SHC1 events in EGFR signaling";"Regulation of signaling by CBL";"Clathrin-mediated endocytosis";"SHC1 events in ERBB2 signaling";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR4 signaling";"GRB2 events in ERBB2 signaling";"Interleukin receptor SHC signaling";"Negative regulation of FGFR2 signaling";"Signal regulatory protein family interactions";"Downstream signal transduction";"RAF/MAP kinase cascade";"Spry regulation of FGF signaling";"EGFR Transactivation by Gastrin";"SOS-mediated signalling";"SHC1 events in ERBB4 signaling";"PI-3K cascade:FGFR4";"EGFR downregulation";"GAB1 signalosome";"Activated NTRK2 signals through RAS";"Insulin receptor signalling cascade";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of MET activity";"MET activates RAP1 and RAC1";"RET signaling";"SHC-mediated cascade:FGFR1";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"PI-3K cascade:FGFR3";"SHC-mediated cascade:FGFR4";"Signaling by FGFR1 in disease";"MET activates RAS signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Signalling to RAS";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by EGFRvIII";"Regulation of KIT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Activated NTRK2 signals through PI3K";"PIP3 activates AKT signaling";"Tie2 Signaling";"Signaling by ERBB2 KD Mutants";"Signaling by FGFR4 in disease";"Signal attenuation";"FRS-mediated FGFR4 signaling";"GRB2 events in EGFR signaling";"DAP12 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization" XP_014095383.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014089396.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_014092373.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_014088689.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014092239.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" XP_014088941.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_014099724.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014099533.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014089331.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014096777.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014099232.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014094004.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_014092767.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014088193.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_014091413.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_014092674.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_014090136.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014092501.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Amino acid transport across the plasma membrane";"Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_014093004.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014100032.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014098563.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_014087741.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014089271.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014100848.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014098522.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014087803.1 7 Reactome: R-HSA-1474151;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-69205;MetaCyc: PWY-3841 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"G1/S-Specific Transcription";"Folate transformations II (plants)" XP_014097062.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014091997.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_014090424.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014103563.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014092258.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_014100749.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014086535.1 11 Reactome: R-HSA-8964539;Reactome: R-HSA-210455;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675 "Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)" XP_014090029.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_014099264.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014093306.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014095851.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-141444 "HCMV Late Events";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014096810.1 7 KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" XP_014103662.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014103453.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_014102457.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014102722.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_014090486.1 11 Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_014096878.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097540.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408 "Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase" XP_014095972.1 17 Reactome: R-HSA-4086398;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-9020702 "Ca2+ pathway";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"Downstream TCR signaling";"Interleukin-1 signaling" XP_014103353.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014087238.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014091376.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014102696.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014093360.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014085478.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_014085283.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014089321.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_014092306.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014100589.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014099124.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014087559.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399 "Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_014102242.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_014086568.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014098797.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_014085397.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014096114.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_014096949.1 10 MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-6527 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation" XP_014099216.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_014101815.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014092083.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014092856.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014092387.1 6 KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11 "Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis" XP_014087956.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions" XP_014089264.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_014085313.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014098095.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014091345.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014095009.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA" XP_014094205.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014090440.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014096503.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_014099615.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014096902.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_014093923.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014094564.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014086283.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_014092537.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_014085791.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014089547.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_014096414.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014091047.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097416.1 29 MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-6342;MetaCyc: PWY-6871;MetaCyc: PWY-6587;MetaCyc: PWY-5078;KEGG: 00982+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-6313;MetaCyc: PWY-6802;MetaCyc: PWY-5076;MetaCyc: PWY-7396;MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5486;MetaCyc: PWY-5079;KEGG: 00071+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7111 "L-valine degradation II";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"L-tryptophan degradation V (side chain pathway)";"Naphthalene degradation";"(S)-propane-1,2-diol degradation";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II";"Drug metabolism - cytochrome P450";"Chloroalkane and chloroalkene degradation";"Acetaldehyde biosynthesis I";"Serotonin degradation";"Salidroside biosynthesis";"L-leucine degradation III";"Butanol and isobutanol biosynthesis (engineered)";"Phenylethanol biosynthesis";"Tyrosine metabolism";"L-methionine degradation III";"Retinol metabolism";"Chitin degradation to ethanol";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"L-phenylalanine degradation III";"Fatty acid degradation";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)" XP_014088851.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014101611.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014090138.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014094016.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014092126.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" XP_014095214.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014087111.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014091332.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014097874.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014101124.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093912.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_014095811.1 11 Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_014091245.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014087248.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_014093442.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_014091630.1 8 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_014090525.1 26 Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-69205;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-4615885;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-69091;Reactome: R-HSA-174417;Reactome: R-HSA-5656121;Reactome: R-HSA-1362277;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606 "Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA replication proteins";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLI";"Transcription of E2F targets under negative control by DREAM complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_014086445.1 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096 "MPS I - Hurler syndrome";"CS/DS degradation";"HS-GAG degradation" XP_014098950.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014088197.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_014087519.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_014088741.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014093698.1 15 Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408 "MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation" XP_014088001.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_014088090.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_014098471.1 3 KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" XP_014098129.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_014097987.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-879415;Reactome: R-HSA-446203 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation" XP_014087222.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-167172 "RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome" XP_014094657.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014092454.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014098289.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_014089123.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014102680.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_014088321.1 1 Reactome: R-HSA-419771 "Opsins" XP_014091537.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_014091569.1 9 Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-198933;Reactome: R-HSA-216083;Reactome: R-HSA-6785807;Reactome: R-HSA-6798695;Reactome: R-HSA-202733;Reactome: R-HSA-166016;Reactome: R-HSA-3000178 "Syndecan interactions";"Molecules associated with elastic fibres";"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell";"Integrin cell surface interactions";"Interleukin-4 and Interleukin-13 signaling";"Neutrophil degranulation";"Cell surface interactions at the vascular wall";"Toll Like Receptor 4 (TLR4) Cascade";"ECM proteoglycans" XP_014100210.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_014101847.1 10 KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_014098158.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_014099050.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092266.1 4 KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" XP_014096998.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_014096243.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_014097207.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_014091242.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-166208 "HSF1-dependent transactivation";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling" XP_014092654.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_014087688.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_014088359.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy" XP_014092477.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling downstream of RAS mutants" XP_014091838.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_014088683.1 33 MetaCyc: PWY-7798;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00625+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5480;MetaCyc: PWY-5486;Reactome: R-HSA-71384;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7111;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-5082;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5078;MetaCyc: PWY-6342;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00071+1.1.1.1;KEGG: 00680+1.1.1.284;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-1801;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-5751 "Protein S-nitrosylation and denitrosylation";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Chloroalkane and chloroalkene degradation";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Ethanol oxidation";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to isobutanol (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Acetaldehyde biosynthesis I";"L-leucine degradation III";"Salidroside biosynthesis";"L-methionine degradation III";"Tyrosine metabolism";"L-isoleucine degradation II";"Noradrenaline and adrenaline degradation";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Naphthalene degradation";"L-phenylalanine degradation III";"Fatty acid degradation";"Methane metabolism";"Retinol metabolism";"Chitin degradation to ethanol";"Formaldehyde oxidation II (glutathione-dependent)";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"Phenylethanol biosynthesis" XP_014097772.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014094559.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_014096486.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_014090028.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014088318.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_014093089.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_014097255.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014093834.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014090887.1 3 KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217 "Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage" XP_014085459.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014097286.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014091005.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-167590 "ROS and RNS production in phagocytes";"Ion channel transport";"Blockage of phagosome acidification";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Nef Mediated CD4 Down-regulation" XP_014086291.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014103716.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_014088218.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014093324.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014089278.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014101895.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014101868.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_014103564.1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692 "SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity" XP_014085710.1 23 Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-418594;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-8964616 "Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42" XP_014102742.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014103442.1 5 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex" XP_014085274.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_014091337.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014095562.1 14 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition" XP_014086124.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_014088120.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_014090298.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_014091977.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2" XP_014099605.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014098644.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014096895.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_014094837.1 7 KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980 "Photosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Oxidative phosphorylation";"ATP biosynthesis" XP_014090569.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014103513.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_014094788.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_014095431.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis" XP_014092408.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_014089334.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014087871.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014086348.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_014090443.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_014092739.1 3 Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90 "Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_014103736.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_014099212.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis" XP_014100403.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_014102224.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-69017 "Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Hedgehog 'on' state";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" XP_014092125.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-191859 "SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"snRNP Assembly" XP_014100583.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014094333.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014091378.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014092234.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014096954.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783 "Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome" XP_014099663.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501 "Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_014094231.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014098111.1 15 MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-5484 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)" XP_014103483.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014091588.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_014085851.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014098066.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014097458.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_014093859.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014088537.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014097771.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014101489.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014093113.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014099381.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014100824.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" XP_014097931.1 4 Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_014101923.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014089459.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086689.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014096962.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_014087872.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092784.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014102990.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_014102314.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014085729.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014096359.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_014098004.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014098523.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_014096069.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_014088850.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014093031.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014087267.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014102681.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844 "Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_014089889.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_014085958.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014094835.1 7 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Oxidative phosphorylation";"ATP biosynthesis";"Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014090346.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_014086972.1 8 MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5738;MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5739 "GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis" XP_014090484.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014086025.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490 "Neutrophil degranulation";"MHC class II antigen presentation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation" XP_014090552.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_014097664.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014095357.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014092596.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation" XP_014095767.1 4 Reactome: R-HSA-446199;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108 "Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis" XP_014086372.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014097573.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014090423.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "mTOR signalling";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" XP_014094675.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014099695.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014102669.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_014090915.1 3 MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis" XP_014095679.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014096522.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014091443.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_014085872.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014098193.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090702.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014094887.1 11 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;Reactome: R-HSA-168138;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1632852;KEGG: 04070+2.7.1.137 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Toll Like Receptor 9 (TLR9) Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"PI3K Cascade";"Macroautophagy";"Phosphatidylinositol signaling system" XP_014098034.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014102547.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_014090377.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014089337.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014087590.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014099475.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_014100806.1 10 Reactome: R-HSA-913709;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-162699;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374 "O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"N-Glycan biosynthesis";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_014087492.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014102607.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_014100261.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_014102962.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_014094726.1 6 KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820 "Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)" XP_014090749.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_014089798.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014100895.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014102225.1 57 Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442 "Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs" XP_014102964.1 25 Reactome: R-HSA-8940973;Reactome: R-HSA-8951911;Reactome: R-HSA-8939902;Reactome: R-HSA-8936459;Reactome: R-HSA-8939245;Reactome: R-HSA-8939256;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8939247;Reactome: R-HSA-8931987;Reactome: R-HSA-8941284;Reactome: R-HSA-8939243;Reactome: R-HSA-8949275;Reactome: R-HSA-8934593;Reactome: R-HSA-9616222;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8878166;Reactome: R-HSA-9018519;Reactome: R-HSA-8941858;Reactome: R-HSA-8941326;Reactome: R-HSA-8877330;Reactome: R-HSA-8941333;Reactome: R-HSA-8939246;Reactome: R-HSA-8939242 "RUNX2 regulates osteoblast differentiation";"RUNX3 regulates RUNX1-mediated transcription";"Regulation of RUNX2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX1 Expression and Activity";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"Transcriptional regulation by RUNX2";"Estrogen-dependent gene expression";"Regulation of RUNX3 expression and activity";"RUNX2 regulates bone development";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes" XP_014103721.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_014091106.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014091861.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_014094633.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014100702.1 4 MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_014100569.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014085218.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_014095495.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines" XP_014102017.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014092565.1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5 "C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism" XP_014095907.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014087043.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_014095943.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_014087619.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014088614.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events" XP_014086547.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_014102318.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014092787.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_014102549.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922 "Folding of actin by CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_014087089.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014098646.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014091710.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014097991.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014090268.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014102511.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014087227.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_014089096.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_014096936.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_014099914.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_014090001.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014086062.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870 "G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins" XP_014094641.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014094596.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_014099130.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_014095669.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014095734.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_014094487.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014087535.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_014087329.1 3 MetaCyc: PWY-6100;Reactome: R-HSA-71262;KEGG: 00310+1.14.11.8 "L-carnitine biosynthesis";"Carnitine synthesis";"Lysine degradation" XP_014098115.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014098025.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014086217.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_014092880.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014094307.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014090045.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014101592.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_014092625.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014091193.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_014095430.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-3301854 "snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly" XP_014088643.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014095486.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_014096079.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014095935.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_014092564.1 13 MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690 "Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)" XP_014094568.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_014097194.1 11 Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-202733;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170 "HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions" XP_014096870.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014095237.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014090645.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014088354.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014088127.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_014094623.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014097956.1 7 Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines" XP_014095078.1 9 Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-975634 "Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Retinoid metabolism and transport" XP_014085525.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;MetaCyc: PWY-7511;Reactome: R-HSA-901032 "XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)" XP_014087627.1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_014103486.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014098374.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014093514.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014092814.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014102391.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_014102570.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014101690.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014094878.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014101796.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014086293.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_014099177.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014101588.1 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_014094800.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085183.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014096982.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_014093916.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014086576.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014099068.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014092213.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014085748.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_014100614.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014091880.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014101180.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;Reactome: R-HSA-913709 "Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins" XP_014099222.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014088524.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_014100756.1 3 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635;Reactome: R-HSA-189085 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)";"Digestion of dietary carbohydrate" XP_014086160.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014091620.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_014100143.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014096945.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014090019.1 4 MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;Reactome: R-HSA-189483 "Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation" XP_014091775.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014089536.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_014094754.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_014098622.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014102243.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269 "Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_014099073.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014089896.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014096231.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_014090737.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014095222.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014097532.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014085707.1 23 Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-418594 "G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events" XP_014095479.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_014099047.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_014088080.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_014103489.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014102255.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_014102072.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_014091060.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2" XP_014096563.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_014097880.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014091813.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_014085863.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014088412.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_014094123.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014094194.1 10 Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity" XP_014093072.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014086890.1 3 KEGG: 00232+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00230+1.7.3.3 "Caffeine metabolism";"Urate conversion to allantoin I";"Purine metabolism" XP_014089894.1 6 MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-5668 "Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PA";"Synthesis of PG";"Cardiolipin biosynthesis I" XP_014087805.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014087262.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_014088109.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014087085.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4570464 "HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins" XP_014085401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014086706.1 5 MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_014103583.1 17 Reactome: R-HSA-6796648;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"T cell receptor signaling pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_014090282.1 7 Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36 "Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism" XP_014103117.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014085254.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_014102694.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_014103653.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_014094105.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014088821.1 25 Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276 "Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"Kinesins";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_014098501.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014098540.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_014088679.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014094274.1 5 Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042 "Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle" XP_014088931.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_014087042.1 4 Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48 "Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_014096104.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014089919.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014092740.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_014101703.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_014099959.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014100737.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014092606.1 9 KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle" XP_014091836.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Cyclin E associated events during G1/S transition" XP_014093336.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014102700.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014094670.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014092160.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_014087709.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_014103759.1 5 MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667 "CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_014095814.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014089732.1 7 Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-165054 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA" XP_014091011.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014092662.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_014089744.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_014088737.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014092599.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport" XP_014093516.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_014097150.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014096287.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014085812.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014090982.1 8 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014092257.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_014093406.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_014089537.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_014100410.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014088920.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_014103111.1 12 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-205043 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus" XP_014092390.1 6 MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis" XP_014100906.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014098861.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014095913.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014087781.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_014090515.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_014098047.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014098924.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014088605.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014092927.1 7 KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-8004;Reactome: R-HSA-71336;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_014092001.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_014094301.1 2 Reactome: R-HSA-8983711;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon alpha/beta signaling" XP_014102885.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_014090478.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014102619.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014089622.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014103694.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_014097019.1 20 Reactome: R-HSA-163765;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8 "ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Mitochondrial protein import";"Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Citrate cycle (TCA cycle)" XP_014097466.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014095399.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014093615.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014097654.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014088797.1 13 KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101 "Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"CS/DS degradation" XP_014100609.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014094238.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014100264.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_014103340.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_014103166.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014098838.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_014092248.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_014094166.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_014096829.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014102735.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014087240.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014097016.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_014091387.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014096347.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014092124.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_014097687.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_014095513.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"ECM proteoglycans";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_014100225.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641257 "Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of AXIN" XP_014088248.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014085137.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014086241.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014089890.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_014100397.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_014090495.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014093595.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593 "Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity" XP_014088054.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014099951.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014093334.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014101376.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093053.1 4 Reactome: R-HSA-70688;MetaCyc: PWY-5737;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_014088948.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014094790.1 4 MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism" XP_014090942.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014102699.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085661.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC" XP_014098412.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014102516.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014093180.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_014102445.1 1 MetaCyc: PWY-6938 "NADH repair" XP_014103157.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014091037.1 7 Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-983231;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-9029569 "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"Factors involved in megakaryocyte development and platelet production";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_014087057.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014094624.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_014086705.1 11 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery" XP_014088159.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_014099576.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014103695.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_014102484.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014090875.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014102185.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014094928.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014098431.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014095136.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014091707.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_014088334.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014096822.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_014096475.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014101380.1 6 MetaCyc: PWY-7791;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7790 "UMP biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis II" XP_014096957.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_014095650.1 20 Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5685938 "Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Polymerase switching";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)" XP_014097670.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014092274.1 17 MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5743 "Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Pyruvate metabolism";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate cycle" XP_014103724.1 7 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_014092053.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_014090888.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_014103115.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014085963.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014092426.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Degradation of the extracellular matrix";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_014102047.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_014086564.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_014097976.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014101131.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014096624.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014085679.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_014087656.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014092411.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-5578749;Reactome: R-HSA-171306;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-606279;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-427389;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-5250924;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-110329;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-2299718;Reactome: R-HSA-2559582;Reactome: R-HSA-110330;Reactome: R-HSA-9616222;Reactome: R-HSA-5334118;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73728;Reactome: R-HSA-201722;Reactome: R-HSA-427359;Reactome: R-HSA-1221632;Reactome: R-HSA-8939236 "HDACs deacetylate histones";"Transcriptional regulation by small RNAs";"Packaging Of Telomere Ends";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination";"HCMV Late Events";"PKMTs methylate histone lysines";"HCMV Early Events";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"B-WICH complex positively regulates rRNA expression";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"Cleavage of the damaged pyrimidine";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Condensation of Prophase Chromosomes";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation of granulopoiesis";"DNA methylation";"Estrogen-dependent gene expression";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Promoter Opening";"Formation of the beta-catenin:TCF transactivating complex";"SIRT1 negatively regulates rRNA expression";"Meiotic synapsis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_014098211.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014096130.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870 "G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins" XP_014102682.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_014087879.1 5 Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;MetaCyc: PWY-5046 "Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_014097137.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-111367 "snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs" XP_014091483.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_014102673.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014090207.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_014090350.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014085486.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014098151.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_014089118.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_014093746.1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943 "Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates" XP_014099465.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_014102222.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014099534.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014095549.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_014085597.1 1 KEGG: 00906+1.23.5.1 "Carotenoid biosynthesis" XP_014097370.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014090469.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014091774.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_014085921.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014089682.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_014088576.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092562.1 57 Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178 "Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_014093467.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014089531.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014085659.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-111464 "Transcriptional Regulation by E2F6";"Neutrophil degranulation";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_014091186.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_014089303.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_014087830.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716 "EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_014089637.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014091072.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014095973.1 17 Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-4086398;Reactome: R-HSA-9645460 "Downstream TCR signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ca2+ pathway";"Alpha-protein kinase 1 signaling pathway" XP_014102631.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014096072.1 10 MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-3841;MetaCyc: PWY-6613;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201 "Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I" XP_014097432.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014102272.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_014095739.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014091820.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014089795.1 11 MetaCyc: PWY-6174;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;MetaCyc: PWY-5123;MetaCyc: PWY-922;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-7102;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis" XP_014099726.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_014101409.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014096003.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_014085852.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014097684.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_014088907.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014090946.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_014092597.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_014086799.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_014103081.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_014097869.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014085593.1 11 Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "p38MAPK events";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_014088320.1 1 Reactome: R-HSA-419771 "Opsins" XP_014103592.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464 "HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins" XP_014095558.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014099108.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014091629.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_014094403.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465 "Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins" XP_014085564.1 12 Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263 "Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Methane metabolism";"Gluconeogenesis" XP_014088788.1 13 Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18 "Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450" XP_014101132.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014099412.1 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_014088739.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014091256.1 17 Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_014098228.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_014098519.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014100063.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014089875.1 5 KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;Reactome: R-HSA-73621;MetaCyc: PWY-5532 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)" XP_014100190.1 4 Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014093690.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014088309.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014093317.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014087833.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257 "AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion" NP_957750.1 7 MetaCyc: PWY-3781;MetaCyc: PWY-5083;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692;MetaCyc: PWY-4302 "Aerobic respiration I (cytochrome c)";"NAD/NADH phosphorylation and dephosphorylation";"Respiratory electron transport";"Complex I biogenesis";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)" XP_014096373.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014087000.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014089938.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014101388.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_014087440.1 7 Reactome: R-HSA-2142691;Reactome: R-HSA-9018681;Reactome: R-HSA-9018896;Reactome: R-HSA-6798695;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of protectins";"Biosynthesis of E-series 18(S)-resolvins";"Neutrophil degranulation";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins" XP_014093194.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014093973.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" NP_957749.1 7 MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-5083;KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-6692;MetaCyc: PWY-4302 "Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Oxidative phosphorylation";"Complex I biogenesis";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)" XP_014088954.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014097571.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014103210.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_014087951.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014088227.1 12 Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861 "Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_014101985.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_014088268.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014090421.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014102609.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014096520.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014095271.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_014095462.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014101733.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014099182.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2024101 "Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"CS/DS degradation" XP_014087396.1 12 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-76066 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_014094730.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014092590.1 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014093370.1 8 Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_014103152.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014103409.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-163680;Reactome: R-HSA-9613354 "Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy" XP_014092694.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" XP_014096357.1 29 Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-5656121;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-110320 "Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Translesion synthesis by POLI";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH" XP_014091666.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014085884.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014088244.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014095368.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_014090267.1 10 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Ub-specific processing proteases";"HATs acetylate histones";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Thermogenesis" XP_014100076.1 5 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_014103465.1 57 Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695 "SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation" XP_014097944.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014102046.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_014097467.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014102238.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_014102568.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014085568.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_014088734.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014098090.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014096915.1 8 KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556 "Photosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ATP biosynthesis";"Oxidative phosphorylation";"ROS and RNS production in phagocytes" XP_014098643.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014099025.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_014100662.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014100602.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014096455.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014102956.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014100692.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014101674.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_014098356.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane" XP_014094029.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014102235.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014099579.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014100607.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_014092246.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757 "VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation" XP_014100079.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_014088391.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014097593.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014101208.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014093951.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014085600.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014097829.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_014091386.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014096790.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955 "Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_014091461.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014087491.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014087171.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_014085449.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014088612.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014086002.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_014090365.1 5 MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Heme biosynthesis" XP_014092044.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014096590.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839 "Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis" XP_014086435.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-5696400;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Dual Incision in GG-NER";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex" XP_014097227.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_014089820.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_014086753.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014093849.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_014100779.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014097764.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_014097979.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_014087332.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014085450.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014089350.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_014100566.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_014096554.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_014101581.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014095182.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014093691.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014100394.1 12 Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13 "Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_014092649.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_014092838.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_014099536.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014085721.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_014090778.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014090224.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi" XP_014098712.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_014099178.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014086334.1 13 MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7254 "Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)" XP_014098896.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014089699.1 4 Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation" XP_014096073.1 10 Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5030;MetaCyc: PWY-6613 "Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_014099478.1 8 KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27 "Cysteine and methionine metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_014097111.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" XP_014100808.1 10 KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864 "Purine metabolism";"Neutrophil degranulation";"Amyloid fiber formation";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events" XP_014088148.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014102376.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_014087124.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014087375.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014094385.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014095555.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_014097468.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014102384.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014103310.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" XP_014097391.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014099990.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014096646.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_014085563.1 12 KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis" XP_014088721.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014097249.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_014090696.1 4 Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014086809.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation" XP_014085907.1 8 KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5668;MetaCyc: PWY-7817;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Synthesis of PG";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014091943.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_014094797.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014093857.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_014088843.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014091009.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014100967.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014091555.1 26 Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-201722;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-3134973 "Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production" XP_014088957.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014093358.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" XP_014100571.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014097570.1 11 Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_014095218.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089619.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_014085533.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_014100330.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_014101084.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014096585.1 17 MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reductive TCA cycle II";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)" XP_014095356.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_014100354.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_014087067.1 5 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014091837.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_014091642.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_014097039.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014092118.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_014086572.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)" XP_014094856.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_014094689.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014091572.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_014089224.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" XP_014098968.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_014086438.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_014098494.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014094884.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" XP_014095030.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" NP_957748.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014085870.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014095712.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014098923.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014088952.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014092247.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400 "PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_014088976.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_014091890.1 8 Reactome: R-HSA-4086398;Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-4641263;Reactome: R-HSA-5099900;Reactome: R-HSA-373080;Reactome: R-HSA-8856828;Reactome: R-HSA-4608870 "Ca2+ pathway";"Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Regulation of FZD by ubiquitination";"WNT5A-dependent internalization of FZD4";"Class B/2 (Secretin family receptors)";"Clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins" XP_014093010.1 10 MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5890 "Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-10 biosynthesis" XP_014098550.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_014102729.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014098621.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7858 "10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II" XP_014099359.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014093291.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_014092491.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014101901.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" XP_014098142.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA" XP_014095485.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_014085464.1 29 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER" XP_014103469.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_014097700.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" XP_014091748.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_014087023.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_014085893.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014103693.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014094195.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-182971;Reactome: R-HSA-432720 "Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"EGFR downregulation";"Lysosome Vesicle Biogenesis" XP_014096318.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014095226.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014094597.1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"Human cytomegalovirus infection" XP_014093741.1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_014088713.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52 "Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_014093404.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_014085646.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085196.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_014101160.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_014088119.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_014103267.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_014095933.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_014102142.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014103430.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014096177.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_014098094.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014091183.1 5 MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Neutrophil degranulation" XP_014102504.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_014090227.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_014088146.1 4 Reactome: R-HSA-1474228;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919 "Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Crosslinking of collagen fibrils" XP_014103450.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014102310.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014090480.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_014088661.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014092085.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014090683.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014087362.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014097737.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" XP_014088949.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014088091.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_014092712.1 3 MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_014087810.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_014085648.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014093005.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086632.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_014096696.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014095967.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_014088752.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-5667;Reactome: R-HSA-75896;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.42;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;MetaCyc: PWY-8051 "Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Anandamide biosynthesis I" XP_014093777.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014090978.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014094296.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014099769.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-937041 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1" XP_014092804.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014087866.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_014096557.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_014097770.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014095058.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-5941;Reactome: R-HSA-6798695;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724 "Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Neutrophil degranulation";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II" XP_014088219.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014094346.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014094603.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014098204.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_014092862.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014103611.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014097369.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014100899.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014103012.1 6 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)" XP_014087612.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014090543.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014086923.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_014103139.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014093244.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097 "mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway" XP_014102389.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_014101371.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014092250.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I" XP_014091758.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994 "PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_014098974.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_014094791.1 4 KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621 "Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism" XP_014101047.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014103426.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_014094687.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014102002.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_014085281.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014098516.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014096830.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014090642.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014093163.1 5 KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_014086161.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_014091784.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014093928.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014094567.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014094073.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014091128.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_014103077.1 17 Reactome: R-HSA-74217;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-5532;MetaCyc: PWY-6620;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1 "Purine salvage";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II" XP_014089554.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_014096550.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_014096925.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014100598.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014089865.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_014102654.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_014089467.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014099370.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_014093319.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_014097392.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_014085591.1 11 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Thermogenesis" XP_014098835.1 12 KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;KEGG: 00920+2.7.7.4;KEGG: 00261+2.7.7.4 "Purine metabolism";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Transport and synthesis of PAPS";"Selenate reduction";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Monobactam biosynthesis" XP_014092009.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_014096781.1 5 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955 "RAF activation";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_014098890.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_014088017.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_014098596.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014094676.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014093346.1 7 Reactome: R-HSA-77348;Reactome: R-HSA-1989781;Reactome: R-HSA-77346;KEGG: 00071+1.3.8.7;Reactome: R-HSA-77288;KEGG: 00280+1.3.8.7;MetaCyc: PWY-7094 "Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"PPARA activates gene expression";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Valine, leucine and isoleucine degradation";"Fatty acid salvage" XP_014091536.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_014099165.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014091506.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_014102168.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014089647.1 57 Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-4608870 "FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"Hedgehog 'on' state";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins" XP_014091709.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014102507.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_014086944.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014100203.1 8 KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1 "Fructose and mannose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis" XP_014098198.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095021.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014090724.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014093941.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014102674.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014088403.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582 "Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)" XP_014098711.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_014096903.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014092052.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_014097871.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014091350.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099970.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_014099015.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_014103155.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014093598.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" XP_014093313.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204 "D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" XP_014086621.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014089864.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014090290.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_014088337.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014099203.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751 "Signal transduction by L1";"WNT mediated activation of DVL";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Regulation of PTEN stability and activity" XP_014092273.1 17 Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-200425;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-2426168;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1 "Biotin transport and metabolism";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"Carnitine metabolism";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Activation of gene expression by SREBF (SREBP)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_014096776.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014099262.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014096967.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_014096000.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014091444.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism" XP_014086275.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091244.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_014097011.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014097430.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014090876.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014096398.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7854 "Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_014095389.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014085669.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014091528.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_014102677.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-69017 "Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" XP_014102120.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_014103172.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095273.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014100080.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_014094295.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014101715.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098453.1 57 Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870 "G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins" XP_014088992.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014102141.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014091952.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_014097141.1 29 Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Relaxin signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Regulation of TP53 Activity through Methylation";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Stabilization of p53";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation" XP_014091662.1 7 KEGG: 00550+2.7.8.13;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265;MetaCyc: PWY-6470;Reactome: R-HSA-4549356 "Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2" XP_014093911.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_014088530.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_014088594.1 4 Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_014095358.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_014089835.1 6 KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12 "Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism" XP_014097911.1 10 MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385 "Glycolysis IV (plant cytosol)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)" XP_014085510.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" XP_014087397.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014100573.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014090710.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_014099435.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014087740.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014094464.1 4 Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis" XP_014090804.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014097884.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014091188.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097960.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014091729.1 24 Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-4086398;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-420092 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Ca2+ pathway";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors" XP_014099984.1 19 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-3214858;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014093258.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_014094734.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II" XP_014086024.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_014099275.1 8 MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905 "Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"Catecholamine biosynthesis" XP_014094538.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014088740.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014100957.1 10 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;MetaCyc: PWY-7661;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-162699 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose" XP_014098288.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_014092419.1 40 Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE" XP_014095618.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167160 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_014098472.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014101347.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014103710.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014094677.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_014100803.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014095444.1 7 KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352 "Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis" XP_014093610.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014097415.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_014092158.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014091328.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014086738.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_014087614.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014091695.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014097795.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_014089191.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014100627.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_014100145.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014087827.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025 "Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation" XP_014091665.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014099688.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014094221.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014090644.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014101543.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014093706.1 15 Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519 "Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression" XP_014090242.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_014097487.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_014086127.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_014085483.1 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" XP_014101972.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_014086268.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014087638.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_014100654.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_014099440.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014096715.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014087123.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014090134.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014087306.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014090669.1 18 MetaCyc: PWY-7179;KEGG: 00983+2.4.2.3;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;Reactome: R-HSA-73621;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1 "Purine deoxyribonucleosides degradation I";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Pyrimidine catabolism";"Adenine and adenosine salvage III";"Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Purine metabolism" XP_014099043.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_014087845.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014096270.1 19 MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-1622 "Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)" XP_014102503.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_014103692.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_014090007.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014089702.1 4 Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation" XP_014085967.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087946.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_014090333.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014091995.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_014093310.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014092319.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093593.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897 "Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes" XP_014092952.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_014086684.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_014094507.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014091181.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014102698.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014092766.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014098355.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_014098641.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014099021.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_014102925.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014102529.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_014098046.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014088619.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_014100352.1 4 Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11 "Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014090870.1 7 KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484 "Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_014096933.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_014100852.1 4 KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22 "Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism" XP_014095720.1 52 Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-76071 "NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_014087437.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_014101256.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014100483.1 1 Reactome: R-HSA-419771 "Opsins" XP_014087365.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014101510.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_014088004.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_014093105.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014095165.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014088789.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_014102084.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014100608.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_014088848.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014102130.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014101295.1 6 Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2 "Pyrimidine biosynthesis";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism" XP_014088389.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014090981.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014090425.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014101038.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014090894.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_014094746.1 40 Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-167200 "RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014090419.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014093043.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014094681.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014101460.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014095749.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014097698.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014090176.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014093170.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_014090475.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014091411.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_014093181.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_014095744.1 13 Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism" XP_014094000.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014085364.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_014103782.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014101853.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014098570.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014100030.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" XP_014097155.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation" XP_014101175.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014087987.1 4 MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_014094467.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014090225.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_014092489.1 6 Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723 "Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt" XP_014085557.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014102573.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014088178.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014090643.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014092048.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_014100431.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014097456.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_014097013.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014097824.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171 "Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis" XP_014098089.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014091092.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014102639.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014089188.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_014095915.1 14 Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation" XP_014096213.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014086312.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014085973.1 8 MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18 "Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450" XP_014096077.1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_014094015.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_014099167.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_014091371.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014086795.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014095081.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497 "Platelet sensitization by LDL";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Chylomicron remodeling";"LDL remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"LDL clearance";"VLDL assembly";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors" XP_014096209.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_014100709.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409 "Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis" XP_014096122.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014085134.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014102690.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014090867.1 7 KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00010+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11 "Fructose and mannose metabolism";"Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway" XP_014092704.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_014095522.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_014102587.1 13 MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_014099269.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014092648.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_014093090.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_014093560.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014090442.1 11 Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1 "AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection" XP_014087150.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014099070.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014096846.1 7 KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7219;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism" XP_014103663.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014087836.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716 "EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_014089869.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014086604.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014085523.1 5 Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-901032 "Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"ER Quality Control Compartment (ERQC)" XP_014092526.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_014093549.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014098011.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014100166.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014088718.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_014098678.1 24 Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-163358;Reactome: R-HSA-442720;Reactome: R-HSA-5610783;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-111931;Reactome: R-HSA-163560;Reactome: R-HSA-163615;Reactome: R-HSA-8963896;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780 "Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI2 by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"RET signaling";"Rap1 signalling";"PKA-mediated phosphorylation of CREB";"Triglyceride catabolism";"PKA activation";"HDL assembly";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome" XP_014098093.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_014096932.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_014093639.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014085617.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids" XP_014093185.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014091355.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Pregnenolone biosynthesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_014102481.1 4 Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188;MetaCyc: PWY-5189 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)" XP_014085318.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014099967.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014096467.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014096242.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014087870.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014096194.1 13 Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171 "Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Collagen chain trimerization";"Signaling by PDGF";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Collagen degradation";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions" XP_014092668.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014094636.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_014087242.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014096625.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_014098338.1 4 Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943 "Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014087968.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014101189.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014098620.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7288 "alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_014088675.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_014099509.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091753.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_014098141.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA" XP_014103491.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014093378.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_014085133.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014102957.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014092803.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014090279.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014097179.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014088551.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_014086330.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014095466.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092560.1 19 Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-5627123;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-8964616;Reactome: R-HSA-983231;Reactome: R-HSA-114604;Reactome: R-HSA-428543 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"Myogenesis";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"RHO GTPases activate PAKs";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"G beta:gamma signalling through CDC42";"Factors involved in megakaryocyte development and platelet production";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1" XP_014095216.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014086678.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_014087949.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014095409.1 5 KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;MetaCyc: PWY-4983 "Arginine and proline metabolism";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)" XP_014089051.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014101683.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014102169.1 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Neutrophil degranulation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_014091690.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014093246.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014092100.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_014099339.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_014086909.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_014086516.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_014089500.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014092409.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789 "Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_014096133.1 11 KEGG: 00480+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6549;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-6969 "Glutathione metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"L-glutamine biosynthesis III";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_014096002.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_014089483.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014092500.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_014085343.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-8963889 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Assembly of active LPL and LIPC lipase complexes" XP_014103584.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014095702.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_014091304.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA" XP_014103684.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014102317.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014100195.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014088901.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014085410.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-174437 "Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate from the C-strand" XP_014099456.1 10 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695 "HS-GAG degradation";"Glycosaminoglycan degradation";"Galactose metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Neutrophil degranulation" XP_014103336.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014093433.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_014091944.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_014100391.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014093117.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014091415.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_014092469.1 9 Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-114608 "Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation" XP_014103090.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs" XP_014103515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014091043.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014086947.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014099206.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014100010.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_014089380.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014086068.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_014098841.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695 "IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation" XP_014098154.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_014086276.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014090241.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_014096703.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_014092934.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014103589.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014101537.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_014102750.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_014089182.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Polymerase switching";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" XP_014099418.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_014086235.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_014101967.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_014102341.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014095912.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014095896.1 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" XP_014094095.1 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2 "Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism" XP_014089024.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014098805.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014087609.1 20 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_014094085.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087197.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014102567.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014092307.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Macroautophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_014099357.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014095731.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014103165.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_014088654.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014094645.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_014097942.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_014086813.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-6787639;Reactome: R-HSA-5619078 "Transport of nucleotide sugars";"GDP-fucose biosynthesis";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" XP_014087533.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_014085131.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014094671.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014100268.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095673.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_014095568.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_014094755.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_014090678.1 12 MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-6978;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5857;Reactome: R-HSA-1268020;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5872 "Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_014090223.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014086153.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_014099913.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" XP_014087691.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014096524.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_014097015.1 5 MetaCyc: PWY-4361;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;KEGG: 00270+4.2.1.109 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Formation of apoptosome";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_014092646.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_014098715.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_014094900.1 5 MetaCyc: PWY-7383;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_014102552.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014095073.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_014100682.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_014099265.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014102147.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014102666.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014095813.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014093356.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014085287.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014090968.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014095698.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014098958.1 56 Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5689880 "NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases" XP_014086623.1 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_014099604.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_014092493.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802948 "Platelet degranulation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants" XP_014098378.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089560.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_014101112.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_014085908.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_014099870.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_014089821.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014103617.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014086817.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014090250.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014099169.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014085822.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_014088951.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014098751.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_014095942.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_014101431.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092753.1 12 Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-429947 "Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA" XP_014088102.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014097020.1 20 MetaCyc: PWY-5538;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-1268020;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695 "Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Mitochondrial protein import";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Neutrophil degranulation" XP_014099528.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014098116.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014088468.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014103153.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014098534.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014093898.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014095539.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_014099211.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" XP_014091946.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_014097788.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Insulin receptor recycling" XP_014089509.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014102372.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_014089828.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_014102074.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_014101706.1 15 Reactome: R-HSA-179409;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174048 "APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_014097428.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014096323.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014096075.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_014090422.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096857.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_014096113.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_014094593.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014097405.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_014091708.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_014098811.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_014097143.1 29 KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-6803204;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-912446;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"mTOR signaling pathway";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_014098514.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_014100016.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014085582.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014102566.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1 "G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism" XP_014095519.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014087052.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_014100916.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014087947.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_014103359.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_014096263.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014092505.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014098021.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-8957275;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-202733 "VLDL assembly";"LDL clearance";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Scavenging by Class A Receptors";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Platelet sensitization by LDL";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"LDL remodeling";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Post-translational protein phosphorylation";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall" XP_014086167.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_014094491.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014097978.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_014099660.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_014102603.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_014092621.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_014102239.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_014098113.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014092574.1 18 MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7210;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6 "Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014095112.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "Aggrephagy";"HCMV Early Events";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" XP_014097922.1 4 KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_014092000.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_014098572.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014097372.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014102854.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014102171.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)" XP_014087086.1 5 Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_014089538.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_014089352.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014100853.1 4 KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22 "Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_014103587.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014100445.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_014094698.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_014100386.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014089391.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_014099969.1 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_014098353.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014096407.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014093473.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014100439.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate" XP_014097322.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport" XP_014092371.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014087371.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014085215.1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897 "Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes" XP_014102891.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014095360.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones" XP_014103247.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014087750.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014088615.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014097941.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" XP_014097792.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014100565.1 52 Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-167243;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-75955;Reactome: R-HSA-749476;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-6807505 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes" XP_014099980.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014092099.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_014097291.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_014087245.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014094482.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014101355.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014103221.1 4 KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation" XP_014097669.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_014087674.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014094480.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014102649.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_014096985.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_014087854.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014100357.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014090993.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_014092852.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_014095057.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-7238 "Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Starch degradation II";"Sucrose biosynthesis II" XP_014088591.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014092854.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_014096876.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014095469.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_014087646.1 13 Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism" XP_014089561.1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_014090847.1 4 MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" XP_014100345.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_014093277.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_014095455.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014087090.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014102720.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014097832.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014097491.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_014098973.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_014090344.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_014094059.1 7 Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661 "Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation" XP_014096796.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014089567.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014093088.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_014085811.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014087441.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9018896;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265 "Neutrophil degranulation";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins" XP_014091854.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014101931.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_014086811.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014093139.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014093648.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014086625.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_014096914.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014102761.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_014087943.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014087565.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_014097139.1 29 KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693548;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693568;Reactome: R-HSA-6803207;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648 "Human papillomavirus infection";"Regulation of TP53 Activity through Methylation";"Sensing of DNA Double Strand Breaks";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Stabilization of p53";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of Caspase Activators and Caspases";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Relaxin signaling pathway";"mTOR signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes" XP_014089605.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_014094802.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014097444.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_014098860.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-69017 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" XP_014093122.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014093038.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_014090851.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014095985.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628 "Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_014088785.1 13 KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-6969;Reactome: R-HSA-71403 "Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)" XP_014095672.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_014102524.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014099619.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_014091059.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_014096953.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_014085966.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014090133.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014097953.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014086048.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014087176.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014098467.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_014097420.1 29 MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-6333;MetaCyc: PWY-6313;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-7396;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7111;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5486;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00260+1.1.1.1;KEGG: 00010+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5057;MetaCyc: PWY-7013;MetaCyc: PWY-6342;MetaCyc: PWY-6871;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5078;KEGG: 00625+1.1.1.1 "Phenylethanol biosynthesis";"Tyrosine metabolism";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"Serotonin degradation";"L-leucine degradation III";"Salidroside biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"Retinol metabolism";"Chitin degradation to ethanol";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Fatty acid degradation";"L-phenylalanine degradation III";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"Naphthalene degradation";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II";"(S)-propane-1,2-diol degradation";"Noradrenaline and adrenaline degradation";"3-methylbutanol biosynthesis (engineered)";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II";"Chloroalkane and chloroalkene degradation" XP_014089454.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014092708.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_014103215.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014087442.1 7 Reactome: R-HSA-9018896;Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9020265;Reactome: R-HSA-9023661;Reactome: R-HSA-9018676 "Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of aspirin-triggered D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of D-series resolvins" XP_014090240.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_014103516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014100622.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014089101.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014092188.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_014102308.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014086188.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_014096106.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_014091247.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577 "Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21" XP_014101353.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014099841.1 4 Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255 "UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones";"Other types of O-glycan biosynthesis" XP_014102924.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014096987.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_014097902.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014096552.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_014097403.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014101941.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_014092601.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Ion transport by P-type ATPases";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_014097966.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014087611.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014096698.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014088748.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-75896;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II" XP_014097763.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014087711.1 16 KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.4;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749 "Propanoate metabolism";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Itaconate degradation" XP_014097870.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014096116.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_014099505.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095902.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_014094208.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014099927.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_014095362.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_014100276.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014091010.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014098948.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014101169.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014088494.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014091382.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" XP_014087461.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014093086.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092667.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014088107.1 7 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol" XP_014096212.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-9020702;Reactome: R-HSA-400253;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-69231;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-2644606;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-983168;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-917937;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546 "Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Interleukin-1 signaling";"Circadian Clock";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Cyclin D associated events in G1";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Iron uptake and transport";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling" XP_014097188.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_014103701.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014091104.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014102234.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014097668.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014097387.1 6 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-6922;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)" XP_014096136.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014089945.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_014086076.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014094117.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014092659.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014102140.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014094069.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828 "Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis" XP_014094209.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014094056.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014101729.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014099837.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_014086755.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014091703.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_014090550.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014100104.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253 "Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Circadian Clock" XP_014096910.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_014085686.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014089539.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" XP_014089246.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014095343.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_014093333.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092084.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_014089433.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516 "Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation" XP_014095120.1 6 KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_014090141.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014097263.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014097310.1 4 KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis" XP_014094604.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_014097735.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014103669.1 9 Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-110314 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex" XP_014099943.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014095166.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014102446.1 1 MetaCyc: PWY-6938 "NADH repair" XP_014091246.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_014085415.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014086466.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014099884.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_014097655.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014098247.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014098511.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing" XP_014090729.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane" XP_014093454.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014089521.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_014095965.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014093362.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014093076.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014086423.1 15 Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-389357 "Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"RET signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_014089475.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086414.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014096907.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_014096301.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_014099263.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014099668.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_014091339.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014097312.1 4 Reactome: R-HSA-189451;MetaCyc: PWY-5189;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_014094894.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014092879.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014095484.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase" XP_014099789.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014089998.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014103527.1 19 MetaCyc: PWY-7198;Reactome: R-HSA-380270;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7205;MetaCyc: PWY-7220;Reactome: R-HSA-380320;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism" XP_014086295.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014098636.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_014094206.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014097776.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014095111.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497 "HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_014095300.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_014088093.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_014097690.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_014096984.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_014092406.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442 "Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis" XP_014100972.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling" XP_014085585.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014085638.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014093311.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014095583.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_014096891.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014088913.1 8 KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5744 "Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation" XP_014097320.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-77289 "Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation" XP_014094625.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014088103.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014094465.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418555 "PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events" XP_014098043.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014096181.1 13 Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-186797 "Collagen degradation";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans";"Collagen chain trimerization";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"Signaling by PDGF" XP_014090137.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014103750.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014089829.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_014085186.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_014098379.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096448.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_014092850.1 13 KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883 "Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Anhydromuropeptides recycling II" XP_014090278.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014086364.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014089703.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014094245.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;Reactome: R-HSA-70263;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12 "Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms" XP_014103365.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211976 "PPARA activates gene expression";"Xenobiotics";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Endogenous sterols" XP_014087488.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014094197.1 5 MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)" XP_014103709.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014103217.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014101653.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_014098573.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_014086522.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014092333.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014102842.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_014099664.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_014102596.1 40 Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529 "PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing" XP_014091552.1 26 Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657 "Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"Attenuation phase";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes" XP_014103435.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014089120.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_014090439.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014090163.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_014094486.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014089551.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_014085802.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_014097296.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_014087189.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway" XP_014101217.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014095092.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_014102493.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014097580.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_014091749.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_014099221.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_014087266.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014100040.1 8 KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7400;MetaCyc: PWY-5686;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;MetaCyc: PWY-7790 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis II" XP_014097305.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_014096654.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014085834.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014099563.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097865.1 15 Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7383;MetaCyc: PWY-8004;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6901 "Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation" XP_014096801.1 7 MetaCyc: PWY-6122;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14 "5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_014085369.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_014092875.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_014096529.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014095681.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014092636.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_014099743.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014090688.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014094612.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014100928.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_014102819.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098161.1 9 Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-110314 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex" XP_014090306.1 10 Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014094761.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_014092881.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014098014.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_014089901.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors" XP_014099036.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" XP_014101171.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_014099608.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014100008.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014102679.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_014097014.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014092958.1 4 KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_014094045.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_014089055.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014092027.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_014098286.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_014087125.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014090023.1 7 KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7790 "Drug metabolism - other enzymes";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II" XP_014099071.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014100839.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014086147.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_014093166.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" XP_014085387.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_014103229.1 5 Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation" XP_014087003.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014093914.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097412.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_014092425.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014086794.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Relaxin signaling pathway";"mTOR signaling pathway" XP_014091301.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_014092563.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014103656.1 13 Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-110320;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-8866654;Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-9646399;Reactome: R-HSA-3371511 "Neutrophil degranulation";"Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion Synthesis by POLH";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"E3 ubiquitin ligases ubiquitinate target proteins";"Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Aggrephagy";"HSF1 activation" XP_014102486.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014088869.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014098839.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_014088497.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014090938.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724 "SUMOylation of chromatin organization proteins";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription" XP_014097068.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF activation";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Ras activation upon Ca2+ influx through NMDA receptor" XP_014094357.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014086854.1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport" XP_014088764.1 13 KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-6370;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1 "Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Ascorbate recycling (cytosolic)";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Glutathione metabolism" XP_014086757.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014093586.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_014093051.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014091527.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_014096623.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_014087196.1 17 Reactome: R-HSA-69091;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169 "Polymerase switching";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis" XP_014099549.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_014098009.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014092060.1 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_014097293.1 31 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;Reactome: R-HSA-199220;MetaCyc: PWY-6799;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-7663;MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-6113;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5147 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)" XP_014096409.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014093891.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014092771.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110312 "Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Polymerase switching";"Translesion synthesis by REV1" XP_014097205.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_014093107.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014085810.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014092405.1 6 MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442 "Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis" XP_014095235.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014086624.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_014093164.1 5 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_014095217.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091827.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014094227.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014093308.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014100533.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_014097220.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_014094060.1 7 Reactome: R-HSA-389661;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174 "Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_014097647.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_014094351.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_014102148.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014097196.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7606 "beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_014096983.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_014092280.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_014096382.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_014095412.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014091640.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_014090900.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_014094391.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_014085818.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_014101485.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014092960.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014094694.1 57 Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684 "Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state" XP_014099257.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014100904.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014098463.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014090194.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096994.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014087077.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408 "Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase" XP_014102902.1 10 MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-6174;MetaCyc: PWY-7571;MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;Reactome: R-HSA-1989781 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Mevalonate pathway II (archaea)";"Ferrichrome A biosynthesis";"Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"PPARA activates gene expression" XP_014094219.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_014093109.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014100208.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014086204.1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_014085400.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014101225.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_014102127.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2 "Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_014085619.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_014096538.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" XP_014097589.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014092679.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014097489.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014090677.1 12 MetaCyc: PWY-5872;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5857;Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-6708 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_014094365.1 18 KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1 "Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Arginine and proline metabolism";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_014093413.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014094532.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014093815.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014086075.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014090089.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_014093692.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_014086426.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014090283.1 7 Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36 "Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system" XP_014088885.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"MHC class II antigen presentation" XP_014099300.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_014095526.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400253 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock" XP_014094012.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014103143.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014094963.1 5 KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00533+2.4.1.68 "Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Glycosaminoglycan biosynthesis - keratan sulfate" XP_014096399.1 20 MetaCyc: PWY-7574;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7291;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7288;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-6920;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337 "Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_014088495.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014089868.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014100785.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014090840.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_014093671.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014095161.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014093842.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_014086991.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014103248.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014087630.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_014094513.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_014091531.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_014099675.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014097778.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014088499.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014093026.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014102692.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_014097000.1 4 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_014091926.1 22 Reactome: R-HSA-70263;KEGG: 00030+5.3.1.9;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-622;MetaCyc: PWY-6142;MetaCyc: PWY-5659;MetaCyc: PWY-5054;MetaCyc: PWY-6992;MetaCyc: PWY-8013;MetaCyc: PWY-5384;MetaCyc: PWY-7238;MetaCyc: PWY-7385;MetaCyc: PWY-621;MetaCyc: PWY-6981;KEGG: 00500+5.3.1.9;KEGG: 00010+5.3.1.9;MetaCyc: PWY-3801;Reactome: R-HSA-5628897;Reactome: R-HSA-70171 "Gluconeogenesis";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis III";"Starch biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis";"D-sorbitol biosynthesis I";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation III (sucrose invertase)";"Chitin biosynthesis";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis";"Sucrose degradation II (sucrose synthase)";"TP53 Regulates Metabolic Genes";"Glycolysis" XP_014099696.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014094100.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090571.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014095278.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014102747.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014099421.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014090108.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade" XP_014085892.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_014098569.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014088853.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014085225.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_014091740.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014098155.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport" XP_014092147.1 6 MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_014091751.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014093100.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_014102945.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014097851.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_014103345.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014089007.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014086597.1 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" XP_014087957.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane" XP_014097366.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014089999.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014086187.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_014098019.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014092821.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_014088505.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_014085140.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733 "Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_014087194.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165 "Nephrin family interactions";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth" XP_014099454.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23 "Neutrophil degranulation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Other glycan degradation" XP_014098061.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_014094258.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014085372.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" XP_014094043.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_014098394.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7726;MetaCyc: PWY-7053;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-7724 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_014092315.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014103652.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_014088579.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095651.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits" XP_014086370.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_014088261.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014086431.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_014095242.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-380972 "Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_014098940.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_014098406.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_014087274.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_014090623.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014100698.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_014097600.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014099617.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_014096991.1 4 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" XP_014086886.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_014095629.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014087632.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-6804756 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Regulation of TP53 Activity through Phosphorylation" XP_014098639.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014089955.1 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217 "Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Surfactant metabolism";"Neutrophil degranulation";"Purine metabolism";"Purine salvage" XP_014085560.1 12 MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_014098452.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_014086199.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_014091953.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_014102050.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_014098119.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014085864.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_014087645.1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism" XP_014099241.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_014087367.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014088021.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090777.1 8 KEGG: 00521+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;MetaCyc: PWY-2301;Reactome: R-HSA-1855183 "Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol" XP_014092024.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014098007.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014086005.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014096555.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_014093948.1 16 Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_014100478.1 7 MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phytate degradation I";"Myo-inositol biosynthesis" XP_014088247.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014102456.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780 "Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome" XP_014088943.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014097968.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014090249.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-5689880 "Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases" XP_014098704.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014087966.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014086917.1 13 KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66;KEGG: 00230+3.6.1.9 "Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Purine metabolism";"Purine metabolism" XP_014099119.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014099962.1 6 Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism" XP_014096355.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_014092458.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport" XP_014089653.1 3 KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3 "Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_014095247.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_014102005.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014096501.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014085537.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554 "SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014098266.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_014097065.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_014099616.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014086569.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014095648.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014098192.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099280.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_014093561.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014094757.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685 "Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species" XP_014100443.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014089946.1 18 KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-1622;MetaCyc: PWY-5913;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37 "Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Cysteine and methionine metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism" XP_014101441.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014091776.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_014096886.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014098180.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014098949.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_014090865.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014098468.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_014099809.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014094132.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014085647.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014090186.1 13 KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-561;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-7384;MetaCyc: PWY-5913 "Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)" XP_014096461.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014094271.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014090117.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014089809.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_014094895.1 5 KEGG: 00330+1.14.13.39;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983 "Arginine and proline metabolism";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)" XP_014098149.1 5 MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_014090005.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014088140.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014100610.1 9 Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-9656256 "Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Defective OGG1 Substrate Processing" XP_014092314.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014090770.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_014089389.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090802.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014097759.1 13 MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-6613;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909 "Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)" XP_014087744.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_014102918.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089836.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014100255.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014099779.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014090154.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014095332.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014103585.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014088308.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014089785.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" NP_957754.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014096591.1 7 MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-7838 "Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis" XP_014086708.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_014089074.1 16 Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171;KEGG: 00010+4.2.1.11 "Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_014102396.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_014090142.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014098674.1 24 Reactome: R-HSA-442720;Reactome: R-HSA-5610783;Reactome: R-HSA-5687128;Reactome: R-HSA-163358;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-5621575;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-5610780;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;Reactome: R-HSA-392517 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI2 by the proteasome";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"CD209 (DC-SIGN) signaling";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"Degradation of GLI1 by the proteasome";"DARPP-32 events";"mTOR signaling pathway";"PKA activation";"PKA-mediated phosphorylation of CREB";"HDL assembly";"Triglyceride catabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"RET signaling";"Rap1 signalling" XP_014096436.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014091882.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616 "Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_014101677.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_014097777.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014097368.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014101257.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_014097394.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_014101848.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_014096459.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014098375.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099278.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_014097170.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025 "Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Kinesins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HCMV Early Events";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation" XP_014090514.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014090479.1 3 Reactome: R-HSA-418457;Reactome: R-HSA-392517;Reactome: R-HSA-4086398 "cGMP effects";"Rap1 signalling";"Ca2+ pathway" XP_014103686.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_014090800.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_014093599.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014093947.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014093452.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_014096124.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014085314.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_014091808.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014093895.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_014098510.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway" XP_014085882.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-1660516 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane" XP_014089087.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75035;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557 "Thermogenesis";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT" XP_014098354.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_014093645.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_014096884.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014101491.1 7 MetaCyc: PWY-4702;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363 "Phytate degradation I";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_014099946.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014091954.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_014087195.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001 "Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade" XP_014098537.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_014099527.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014097837.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014086378.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014094076.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014089001.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014103114.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532 "TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer" XP_014095556.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_014100228.1 3 MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403 "5-oxo-L-proline metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_014096067.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_014100116.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014091752.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014086425.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092057.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_014086142.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014096705.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_014087512.1 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine" XP_014097632.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014091628.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014091136.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_014087569.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_014092369.1 14 MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433 "Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)" XP_014099525.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014102778.1 8 MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation" XP_014092886.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014085666.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_014100624.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014089621.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014101019.1 6 MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" XP_014090220.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014088567.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-375276;Reactome: R-HSA-140837 "G alpha (q) signalling events";"G alpha (i) signalling events";"Platelet degranulation";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation" XP_014094697.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014094121.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014097844.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014096385.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014098840.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_014098873.1 6 Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700 "FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling" XP_014085639.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014088228.1 33 Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-69273;Reactome: R-HSA-427413 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"NoRC negatively regulates rRNA expression" XP_014093382.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014095905.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014100200.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_014097977.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014086672.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_014087967.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014095901.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_014098290.1 2 Reactome: R-HSA-8981607;Reactome: R-HSA-203615 "Intracellular oxygen transport";"eNOS activation" XP_014091737.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014100850.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014098736.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014088616.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092909.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_014102200.1 9 KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112 "Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification" XP_014102483.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014093492.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_014103350.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex" XP_014103234.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014100778.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014096107.1 3 KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5 "Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism" XP_014092059.1 5 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_014097243.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014098587.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_014091132.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014101658.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_014094834.1 7 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-2151201;Reactome: R-HSA-163210 "ATP biosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"Cristae formation";"Transcriptional activation of mitochondrial biogenesis";"Formation of ATP by chemiosmotic coupling" XP_014088663.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014085413.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_014096699.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014101339.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_014093787.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014095892.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014087513.1 4 Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22 "Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism" XP_014091431.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_014101667.1 7 Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" XP_014091187.1 5 Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_014093242.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_014093896.1 8 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_014094332.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_014101662.1 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_014092086.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014096880.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014099461.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_014086750.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_014095922.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665 "Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells" XP_014103577.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014095025.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_014089505.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014097702.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_014103623.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_014100546.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_014085285.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014097821.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014095284.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014099261.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014088073.1 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_014098201.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096149.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014101134.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014102594.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_014091202.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_014096909.1 8 MetaCyc: PWY-6556;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;KEGG: 00240+3.5.4.5 "Pyrimidine ribonucleosides salvage II";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine metabolism" XP_014096273.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_014085735.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014098370.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014103367.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014091103.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014094731.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014095646.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014098590.1 10 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_014089693.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014089496.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014097367.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014099422.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-450520 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"HuR (ELAVL1) binds and stabilizes mRNA" XP_014089532.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014099703.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014099522.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014089650.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_014090723.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014094997.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs" XP_014091054.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5099900 "Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4" XP_014094203.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014085420.1 9 Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;Reactome: R-HSA-70263 "Glycolysis";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Gluconeogenesis" XP_014094382.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014088733.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014096035.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014087972.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_014097327.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014090405.1 7 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism" XP_014088122.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814 "Crosslinking of collagen fibrils";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes" XP_014090512.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014102397.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Polo-like kinase mediated events";"G1/S-Specific Transcription" XP_014101100.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014103149.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014095882.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_014094429.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_014099787.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014103428.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014101301.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014100908.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014102578.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014095109.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014087780.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_014094122.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_014093153.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014089477.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_014088027.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014089233.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" XP_014090413.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_014094508.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014097135.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014094330.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_014092549.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_014096894.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_014099220.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014101761.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092495.1 6 Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211 "Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling" XP_014089543.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_014089923.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014102291.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-6785807;Reactome: R-HSA-8878166 "Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2" XP_014095303.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014098713.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_014090147.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014103257.1 179 Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-8849469;Reactome: R-HSA-5658442;Reactome: R-HSA-209543;Reactome: R-HSA-9615710;Reactome: R-HSA-192823;Reactome: R-HSA-9013507;Reactome: R-HSA-72706;Reactome: R-HSA-2173796;Reactome: R-HSA-2565942;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-8876493;Reactome: R-HSA-9613829;Reactome: R-HSA-2173795;Reactome: R-HSA-937041;Reactome: R-HSA-975110;Reactome: R-HSA-168927;Reactome: R-HSA-1236974;Reactome: R-HSA-2408557;Reactome: R-HSA-5655862;Reactome: R-HSA-156827;Reactome: R-HSA-174178;Reactome: R-HSA-201681;Reactome: R-HSA-5678895;Reactome: R-HSA-901032;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2559582;Reactome: R-HSA-5689880;Reactome: R-HSA-2559580;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-6781827;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-450321;Reactome: R-HSA-180585;Reactome: R-HSA-6782210;Reactome: R-HSA-5610780;Reactome: R-HSA-2559585;Reactome: R-HSA-2691232;Reactome: R-HSA-156902;Reactome: R-HSA-9637628;Reactome: R-HSA-69017;Reactome: R-HSA-937072;Reactome: R-HSA-110314;Reactome: R-HSA-912631;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-75815;Reactome: R-HSA-937039;Reactome: R-HSA-5696397;Reactome: R-HSA-1799339;Reactome: R-HSA-5654726;Reactome: R-HSA-9604323;Reactome: R-HSA-9646399;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-400253;Reactome: R-HSA-205043;Reactome: R-HSA-5654727;Reactome: R-HSA-5675221;Reactome: R-HSA-9633012;Reactome: R-HSA-8854050;Reactome: R-HSA-5696394;Reactome: R-HSA-174184;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-2672351;Reactome: R-HSA-4608870;Reactome: R-HSA-209560;Reactome: R-HSA-917729;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-5689901;Reactome: R-HSA-6807004;Reactome: R-HSA-1253288;Reactome: R-HSA-2122947;Reactome: R-HSA-977225;Reactome: R-HSA-3134975;Reactome: R-HSA-975957;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-975144;Reactome: R-HSA-5357905;Reactome: R-HSA-450302;Reactome: R-HSA-69481;Reactome: R-HSA-1358803;Reactome: R-HSA-445989;Reactome: R-HSA-975956;Reactome: R-HSA-975163;Reactome: R-HSA-9013973;Reactome: R-HSA-9020702;Reactome: R-HSA-6783310;Reactome: R-HSA-8866652;Reactome: R-HSA-936440;Reactome: R-HSA-6781823;Reactome: R-HSA-5675482;Reactome: R-HSA-8866654;Reactome: R-HSA-1169091;Reactome: R-HSA-110312;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-3322077;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-9014325;Reactome: R-HSA-69541;Reactome: R-HSA-450408;Reactome: R-HSA-6804757;Reactome: R-HSA-2644606;Reactome: R-HSA-8856825;Reactome: R-HSA-5654732;Reactome: R-HSA-6804760;Reactome: R-HSA-937042;Reactome: R-HSA-5656121;Reactome: R-HSA-5632684;Reactome: R-HSA-9645460;Reactome: R-HSA-72689;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-8875360;Reactome: R-HSA-1169408;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-162588;Reactome: R-HSA-8856828;Reactome: R-HSA-4641257;Reactome: R-HSA-5654733;Reactome: R-HSA-936964;Reactome: R-HSA-8852276;Reactome: R-HSA-2894862;Reactome: R-HSA-5656169;Reactome: R-HSA-5693565;Reactome: R-HSA-5205685;Reactome: R-HSA-168638;Reactome: R-HSA-1295596;Reactome: R-HSA-9636383;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5357956;Reactome: R-HSA-349425;Reactome: R-HSA-9033241;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-174490;Reactome: R-HSA-4641263;Reactome: R-HSA-182971;Reactome: R-HSA-174113;Reactome: R-HSA-8863795;Reactome: R-HSA-532668;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-2122948;Reactome: R-HSA-5689896;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-1236382;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-5684264;Reactome: R-HSA-6791226;Reactome: R-HSA-5689877;Reactome: R-HSA-5696400;Reactome: R-HSA-168928;Reactome: R-HSA-3769402;Reactome: R-HSA-72764;Reactome: R-HSA-68949;Reactome: R-HSA-8948747;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-2979096 "Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of RAS by GAPs";"p75NTR recruits signalling complexes";"Late endosomal microautophagy";"Viral mRNA Translation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of PLK1 Activity at G2/M Transition";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"InlA-mediated entry of Listeria monocytogenes into host cells";"Chaperone Mediated Autophagy";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IKK complex recruitment mediated by RIP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"ER-Phagosome pathway";"Selenocysteine synthesis";"Translesion synthesis by POLK";"L13a-mediated translational silencing of Ceruloplasmin expression";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TCF dependent signaling in response to WNT";"Defective CFTR causes cystic fibrosis";"ER Quality Control Compartment (ERQC)";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Senescence-Associated Secretory Phenotype (SASP)";"Ub-specific processing proteases";"Oxidative Stress Induced Senescence";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Degradation of GLI1 by the proteasome";"Oncogene Induced Senescence";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Peptide chain elongation";"Modulation by Mtb of host immune system";"CDK-mediated phosphorylation and removal of Cdc6";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of signaling by CBL";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Ubiquitin-dependent degradation of Cyclin D";"IRAK1 recruits IKK complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR1 signaling";"Negative regulation of NOTCH4 signaling";"Aggrephagy";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Circadian Clock";"NRIF signals cell death from the nucleus";"Negative regulation of FGFR2 signaling";"Negative regulation of MAPK pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"DNA Damage Recognition in GG-NER";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Stimuli-sensing channels";"Asymmetric localization of PCP proteins";"NF-kB is activated and signals survival";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Metalloprotease DUBs";"Negative regulation of MET activity";"Downregulation of ERBB4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Amyloid fiber formation";"Regulation of innate immune responses to cytosolic DNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TNFR1 signaling";"activated TAK1 mediates p38 MAPK activation";"G2/M Checkpoints";"Downregulation of ERBB2:ERBB3 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1-dependent activation of IRF3/IRF7";"Interleukin-1 signaling";"Fanconi Anemia Pathway";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Negative regulators of DDX58/IFIH1 signaling";"Formation of TC-NER Pre-Incision Complex";"Regulation of necroptotic cell death";"E3 ubiquitin ligases ubiquitinate target proteins";"Activation of NF-kappaB in B cells";"Translesion synthesis by REV1";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Glycogen synthesis";"Dual incision in TC-NER";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Stabilization of p53";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of TP53 Degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Regulation of TP53 Activity through Methylation";"IRAK2 mediated activation of TAK1 complex";"Translesion synthesis by POLI";"Hedgehog 'on' state";"Alpha-protein kinase 1 signaling pathway";"Formation of a pool of free 40S subunits";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"ISG15 antiviral mechanism";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Budding and maturation of HIV virion";"Clathrin-mediated endocytosis";"Degradation of AXIN";"Negative regulation of FGFR4 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Termination of translesion DNA synthesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Pink/Parkin Mediated Mitophagy";"NOD1/2 Signaling Pathway";"Spry regulation of FGF signaling";"Prevention of phagosomal-lysosomal fusion";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"TNFR1-induced NFkappaB signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Peroxisomal protein import";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"Membrane binding and targetting of GAG proteins";"Regulation of FZD by ubiquitination";"EGFR downregulation";"SCF-beta-TrCP mediated degradation of Emi1";"Downregulation of ERBB2 signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activated NOTCH1 Transmits Signal to the Nucleus";"Ovarian tumor domain proteases";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Josephin domain DUBs";"Dual Incision in GG-NER";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Deactivation of the beta-catenin transactivating complex";"Eukaryotic Translation Termination";"Orc1 removal from chromatin";"Regulation of PTEN localization";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_014087971.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-196299;Reactome: R-HSA-111465;Reactome: R-HSA-5467337;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-195253 "S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Beta-catenin phosphorylation cascade";"Apoptotic cleavage of cellular proteins";"APC truncation mutants have impaired AXIN binding";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex" XP_014103720.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014099998.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_014085969.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099786.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014101724.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014093309.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014088262.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014102356.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014099473.1 8 MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_014088660.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014092195.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014090725.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014097295.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_014102748.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014093989.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014102752.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_014097835.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_014100713.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014098114.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014085897.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_014087502.1 9 Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809 "NRAGE signals death through JNK";"GPVI-mediated activation cascade";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"Rho GTPase cycle";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization" XP_014102062.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_014092186.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_014092483.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014092395.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_014093592.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593 "Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity" XP_014096458.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014088613.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014096506.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014094582.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014090912.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014102585.1 13 KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7222 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_014102496.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription" XP_014100359.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014099248.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014092882.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014086218.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2173796 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_014092157.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660 "PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway" XP_014087717.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014102188.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014085132.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014094005.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014086006.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014100334.1 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562 "Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria" XP_014088196.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_014099777.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014087993.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly" XP_014093033.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014096145.1 7 MetaCyc: PWY-7158;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1 "L-phenylalanine degradation V";"Phenylketonuria";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_014088104.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014088667.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014098680.1 24 Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780;Reactome: R-HSA-422356;Reactome: R-HSA-9634600;Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-111931;Reactome: R-HSA-163615;Reactome: R-HSA-8963896;Reactome: R-HSA-381676;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-163358;Reactome: R-HSA-5610783;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-5610785;Reactome: R-HSA-983231 "DARPP-32 events";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome";"Regulation of insulin secretion";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"RET signaling";"Rap1 signalling";"PKA-mediated phosphorylation of CREB";"PKA activation";"HDL assembly";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors";"Degradation of GLI2 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production" XP_014098675.1 24 Reactome: R-HSA-432040;Reactome: R-HSA-111931;Reactome: R-HSA-8963896;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-163560;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-392517;Reactome: R-HSA-8853659;Reactome: R-HSA-5610780;KEGG: 04150+2.7.11.11;Reactome: R-HSA-180024;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-5621575;Reactome: R-HSA-5610787;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-5610783;Reactome: R-HSA-442720;Reactome: R-HSA-5687128;Reactome: R-HSA-163358 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA-mediated phosphorylation of CREB";"HDL assembly";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Triglyceride catabolism";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"Rap1 signalling";"RET signaling";"Degradation of GLI1 by the proteasome";"mTOR signaling pathway";"DARPP-32 events";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"CD209 (DC-SIGN) signaling";"Hedgehog 'off' state";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"Degradation of GLI2 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors" XP_014101641.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014102465.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014101648.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014086946.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014093112.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_014096304.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "MET receptor recycling";"Regulation of signaling by CBL";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_014096709.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014094713.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_014090322.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014092604.1 9 MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981 "Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_014085953.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014103600.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014085362.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_014090206.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014096844.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_014086412.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_014102675.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014086339.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_014088249.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014091102.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014092211.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323 "Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling" XP_014094809.1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-68962 "Dual Incision in GG-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex" XP_014103055.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014087763.1 12 MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;Reactome: R-HSA-196780;MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.2;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.4.13 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine metabolism";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism" XP_014095619.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014089611.1 10 MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6901;KEGG: 00710+2.7.2.3;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6886 "Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)" XP_014102718.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014102751.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_014093345.1 7 KEGG: 00280+1.3.8.7;MetaCyc: PWY-7094;Reactome: R-HSA-77348;Reactome: R-HSA-1989781;Reactome: R-HSA-77346;Reactome: R-HSA-77288;KEGG: 00071+1.3.8.7 "Valine, leucine and isoleucine degradation";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"PPARA activates gene expression";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid degradation" XP_014097696.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014092131.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014088420.1 11 KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-381;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;MetaCyc: PWY-6964;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2 "Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Arginine biosynthesis";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism" XP_014089190.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014099207.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014090140.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014089461.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins" XP_014102157.1 16 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-8951664 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation" XP_014088536.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014102313.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_014100325.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_014103484.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014092552.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014091476.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014086117.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014094488.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014092698.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-5205685 "Aggrephagy";"Josephin domain DUBs";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy" XP_014093199.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014088991.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014096600.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism" XP_014092573.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_014103655.1 9 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" XP_014100390.1 5 MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Starch biosynthesis" XP_014096956.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_014090544.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_014085284.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014091403.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_014090532.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_014092512.1 4 Reactome: R-HSA-176974;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Unwinding of DNA";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_014095219.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098828.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014099136.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014102373.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_014093091.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_014099503.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095816.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590 "Activation of NF-kappaB in B cells";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling" XP_014089862.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014092689.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-176034;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6796648 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Interactions of Tat with host cellular proteins";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes" XP_014085883.1 3 Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_014103219.1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" XP_014101068.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090868.1 7 Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11 "Gluconeogenesis";"Fructose and mannose metabolism";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_014097413.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_014091996.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_014102779.1 8 KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7187 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_014085681.1 23 Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964315;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-500657;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-381676 "Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through BTK";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Presynaptic function of Kainate receptors";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_014093965.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695 "MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation" XP_014090656.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" XP_014093202.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014097683.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014092143.1 6 MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis" XP_014092061.1 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_014102884.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014090205.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4570464 "HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins" XP_014092272.1 17 Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5744;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;MetaCyc: PWY-5789;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765 "Biotin transport and metabolism";"Carnitine metabolism";"Glyoxylate assimilation";"Pyruvate metabolism";"Fatty acid biosynthesis";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression" XP_014090453.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014088577.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092949.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014086943.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014086608.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014091764.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_014089683.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_014102914.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014092993.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_014091801.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_014099691.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_014090758.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_014087058.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014099510.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095220.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098868.1 14 MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;MetaCyc: PWY-2201;MetaCyc: PWY-3661;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1 "Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Photorespiration ";"Methane metabolism";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Folate transformations I";"Glycine betaine degradation I";"Metabolism of folate and pterines";"Cyanoamino acid metabolism" XP_014098054.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" XP_014087129.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_014085214.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897 "MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes" XP_014092361.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73863 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_014091373.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014097272.1 2 Reactome: R-HSA-389957;Reactome: R-HSA-8953750 "Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6" XP_014090391.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_014088849.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014102410.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014089160.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014096671.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014096321.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_014089032.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014101384.1 40 Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167243 "Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_014090621.1 4 Reactome: R-HSA-4719377;Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-162699 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose" XP_014089620.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014096955.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014095245.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"G alpha (i) signalling events";"Hedgehog 'off' state";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation" XP_014090274.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network" XP_014085508.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-983231 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production" XP_014091033.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014103725.1 7 MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;MetaCyc: PWY-6840 "Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis" XP_014085964.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014092189.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling" XP_014086740.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_014091375.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_014103665.1 13 Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-532668;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-6798695;Reactome: R-HSA-8876725;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-8866654 "ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Neutrophil degranulation";"Protein methylation";"Hedgehog ligand biogenesis";"Aggrephagy";"Josephin domain DUBs";"Ovarian tumor domain proteases";"HSF1 activation";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014102382.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014099680.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014094411.1 16 Reactome: R-HSA-1250342;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1963642;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1250347;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-1251985;Reactome: R-HSA-8863795 "PI3K events in ERBB4 signaling";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"SHC1 events in ERBB4 signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4";"Downregulation of ERBB2 signaling" XP_014097301.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014089088.1 17 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-1433557;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75035 "PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Activation of ATR in response to replication stress";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by SCF-KIT";"Thermogenesis";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_014094489.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014101055.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014088712.1 9 KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52 "Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis" XP_014102149.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_014094661.1 3 Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60 "Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation" XP_014093119.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_014101170.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014088311.1 8 Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)" XP_014088997.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_014089546.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_014090003.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014103191.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014098229.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_014102408.1 10 Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "RSK activation";"Recycling pathway of L1";"Thermogenesis";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_014098143.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA" XP_014089397.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_014087747.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_014103654.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;MetaCyc: PWY-7511;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex" XP_014087075.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014100405.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_014097905.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_014090139.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014098946.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_014095463.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014097323.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_014099362.1 11 Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201;Reactome: R-HSA-111457;Reactome: R-HSA-3299685 "Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Respiratory electron transport";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species" XP_014098092.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014095277.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014102864.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_014101523.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014098008.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014088701.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014090145.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014088731.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014093083.1 7 Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_014090090.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014087522.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014085539.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014092243.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400 "CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_014092451.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_014102385.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014085674.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_014088390.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014090717.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_014086009.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014101702.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014087610.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014102237.1 33 Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746 "Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein" XP_014102026.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs" XP_014093217.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014086263.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014090963.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014103517.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_014102161.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_014089085.1 17 Reactome: R-HSA-6796648;Reactome: R-HSA-176187;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-8953750 "TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Thermogenesis";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6" XP_014095992.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014090970.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_014085224.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_014101168.1 3 KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041;Reactome: R-HSA-174403 "Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione synthesis and recycling" XP_014097657.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014096644.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014102444.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014095823.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062 "HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis" XP_014088877.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_014103661.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014087251.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis" XP_014100393.1 6 MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-7900 "Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_014095132.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014087370.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087622.1 13 KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" XP_014086743.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014095424.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166 "Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate" XP_014097758.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014092334.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014090044.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014088498.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014095002.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_014089374.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092749.1 12 Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-166208 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Translation initiation complex formation";"mTORC1-mediated signalling" XP_014090895.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_014093402.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_014085290.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" XP_014098862.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_014087383.1 20 Reactome: R-HSA-380972;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;KEGG: 04151+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"mTOR signalling";"Macroautophagy";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"PI3K-Akt signaling pathway" XP_014091124.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014098117.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014100446.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_014090782.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis" XP_014095671.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014102569.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_014095091.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014093085.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014088905.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014089858.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_014085190.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_014090244.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_014085876.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014088028.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014100339.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_014101633.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_014091532.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_014085407.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014092427.1 14 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Neutrophil degranulation";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_014097418.1 29 MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-6342;MetaCyc: PWY-5078;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6313;MetaCyc: PWY-6333;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-7396;MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5082;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5486;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7111 "L-valine degradation II";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Naphthalene degradation";"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"Noradrenaline and adrenaline degradation";"L-isoleucine degradation II";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Chloroalkane and chloroalkene degradation";"Serotonin degradation";"Acetaldehyde biosynthesis I";"L-leucine degradation III";"Salidroside biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Phenylethanol biosynthesis";"Tyrosine metabolism";"L-methionine degradation III";"Retinol metabolism";"Chitin degradation to ethanol";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to ethanol II";"Fatty acid degradation";"L-phenylalanine degradation III";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)" XP_014093023.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014098714.1 15 Reactome: R-HSA-174178;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176412 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Phosphorylation of the APC/C" XP_014093548.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014093716.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" XP_014099328.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_014097560.1 10 Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17 "Retinoid cycle disease events";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Neutrophil degranulation";"Amyloid fiber formation";"Purine metabolism" XP_014096087.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_014090251.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_014096320.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014091744.1 18 Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;Reactome: R-HSA-1483166 "Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA" NP_957742.1 7 KEGG: 00190+7.1.1.2;Reactome: R-HSA-6799198;MetaCyc: PWY-3781;Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-6692;MetaCyc: PWY-4302 "Oxidative phosphorylation";"Complex I biogenesis";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Fe(II) oxidation";"Aerobic respiration III (alternative oxidase pathway)" XP_014095367.1 5 MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_014088950.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014086067.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098136.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_014093065.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_014085356.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014093583.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_014089924.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014092392.1 6 KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00010+5.4.2.11 "Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis" XP_014092657.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_014086444.1 3 Reactome: R-HSA-2206302;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101 "MPS I - Hurler syndrome";"HS-GAG degradation";"CS/DS degradation" XP_014098208.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014086792.1 8 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection" XP_014085970.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_014099728.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_014094799.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014100599.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014095626.1 8 KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis" XP_014099833.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014088953.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014086546.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21 "Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism" XP_014092871.1 6 Reactome: R-HSA-5685939;Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-69166 "HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate" XP_014091179.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014094196.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004 "Inhibition of membrane repair";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity" XP_014091499.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_014090146.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014099303.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014102216.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_014092609.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_014089581.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_014088751.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8051;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.42;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_014089526.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014101141.1 5 Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-9020702;Reactome: R-HSA-205043 "NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus" XP_014102734.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014094537.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014093304.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014092187.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_014098927.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014091736.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014086123.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_014102704.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_014096717.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014096001.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_014091959.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_014093862.1 10 Reactome: R-HSA-1855167;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6369;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;MetaCyc: PWY-6554 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_014085175.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014087849.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014097112.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_014102425.1 12 MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism" XP_014088875.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_014092954.1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_014103757.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_014089838.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014085414.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014085943.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014091490.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014085176.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014091934.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014085518.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_014095122.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014102534.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_014101818.1 52 Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-73863;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-76061;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-76042;Reactome: R-HSA-76071;Reactome: R-HSA-6782135;Reactome: R-HSA-167200 "RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Termination";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014091368.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014091516.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_014085968.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014101378.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_014100007.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_014097714.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_014094200.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014093644.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_014085559.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014099458.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_014091138.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-139853 "DAG and IP3 signaling";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels" XP_014095529.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206 "Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha" XP_014086097.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014090803.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014091405.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014097910.1 10 MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_014102940.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014095910.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_014091733.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014086289.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_014095941.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_014095753.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-3371453 "SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response" XP_014086674.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_014098831.1 10 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014089349.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_014097546.1 6 Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25 "Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism" XP_014088467.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014096521.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014103135.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_014103596.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014088649.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014103733.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014099156.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014094199.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014093703.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092445.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014087799.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014087352.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014090347.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_014095878.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014085869.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014098985.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014092417.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_014092571.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_014098749.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014089753.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_014095931.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014091320.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014090916.1 57 Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837 "Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Hedgehog 'on' state";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of AXIN";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation" XP_014086893.1 12 MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;MetaCyc: PWY-7233;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5855 "Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)" XP_014087103.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014095909.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014091004.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9639288 "Blockage of phagosome acidification";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1" XP_014098439.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014087676.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014093635.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014102153.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014094774.1 4 Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695 "Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation" XP_014093215.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014097200.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6 "(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation" XP_014086994.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014086419.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_014087040.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_014098242.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_014090342.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_014089917.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014092064.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014090427.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014091510.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_014096190.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781 "ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression" XP_014091519.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_014088224.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_014090080.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" XP_014092238.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_014090300.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_014087675.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014096948.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-7328 "Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_014091003.1 8 Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-182218;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Nef Mediated CD8 Down-regulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Blockage of phagosome acidification";"Ion channel transport";"ROS and RNS production in phagocytes" XP_014099254.1 5 MetaCyc: PWY-8060;KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;Reactome: R-HSA-71336;Reactome: R-HSA-6798695 "2-deoxy-D-ribose degradation I";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Neutrophil degranulation" XP_014098686.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_014098691.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_014095123.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_014098557.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-72731 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP" XP_014093858.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_014099308.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014095404.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014088921.1 9 Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Polymerase switching";"DNA replication initiation" XP_014091392.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014096115.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_014096643.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_014088575.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014103743.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014088214.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_014102613.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014085592.1 11 Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04151+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "p38MAPK events";"Thermogenesis";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"PI3K-Akt signaling pathway";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_014102575.1 4 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_014093416.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_014093732.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014096494.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014095010.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" XP_014093551.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086945.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014102371.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_014099307.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014103018.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_014091474.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014089872.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014099689.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014085421.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014102407.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9603505;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"NTRK3 as a dependence receptor";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex" XP_014085768.1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" XP_014101220.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014089918.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014095856.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014097801.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_014091299.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014090135.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014093351.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_014095936.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_014102538.1 13 Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Macroautophagy";"mTOR signalling";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_014090477.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014099160.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014103349.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_014086606.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014101701.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095322.1 52 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-112382;Reactome: R-HSA-73980;Reactome: R-HSA-73863;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-749476;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing" XP_014094298.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014086814.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_014086083.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24 "FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway" XP_014090066.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014087690.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014091824.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014092380.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_014102711.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014088915.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Macroautophagy" XP_014090126.1 5 KEGG: 00650+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4 "Butanoate metabolism";"Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis and degradation of ketone bodies" XP_014103530.1 19 MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;Reactome: R-HSA-380270;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7176;Reactome: R-HSA-380320;MetaCyc: PWY-7220 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"UTP and CTP de novo biosynthesis";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_014093778.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014088039.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_014096559.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA" XP_014096806.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-8957275 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation" XP_014097699.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014094722.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014093240.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014085749.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014086284.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_014093320.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014102150.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014087652.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087753.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_014096379.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_014093006.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_014098684.1 11 MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00740+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Riboflavin metabolism" XP_014093302.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014098799.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_014103734.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014087651.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_014094656.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014102775.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692 "HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity" XP_014092762.1 24 Reactome: R-HSA-6804757;Reactome: R-HSA-354192;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;Reactome: R-HSA-5218921;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-444257;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158 "Regulation of TP53 Degradation";"Integrin signaling";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"VEGFR2 mediated cell proliferation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Relaxin signaling pathway";"mTOR signaling pathway";"Downstream TCR signaling";"RSK activation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"Activation of AKT2" XP_014085929.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_014094261.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_014090097.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014101419.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014099709.1 7 Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines" XP_014086840.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_014088170.1 10 Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352 "Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis" XP_014093631.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014098800.1 18 KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051 "Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I" XP_014096582.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5461 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation" XP_014092354.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433 "Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)" XP_014102223.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_014094580.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014103168.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014086793.1 8 Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Signaling by Hippo";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014096076.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_014101010.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014093562.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014090008.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-3214847 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HATs acetylate histones" XP_014096420.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014090148.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014099602.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014088121.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" XP_014092664.1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events" XP_014094299.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014085961.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014093075.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014103539.1 12 MetaCyc: PWY-1187;MetaCyc: PWY-7901;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842 "Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Glutathione-mediated detoxification II" XP_014101081.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_014093257.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014089247.1 7 KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;Reactome: R-HSA-2029485 "Glycerophospholipid metabolism";"Synthesis of PG";"Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis" XP_014085801.1 1 Reactome: R-HSA-419771 "Opsins" XP_014097686.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_014101222.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096527.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014086797.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_014090459.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis" XP_014085496.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014100356.1 8 KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6 "Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" XP_014092855.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_014094345.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014092532.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" XP_014098858.1 17 Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;KEGG: 04151+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9022692;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2500257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5663220;KEGG: 05163+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-174178 "SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"PI3K-Akt signaling pathway";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Regulation of MECP2 expression and activity";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Resolution of Sister Chromatid Cohesion";"Thermogenesis";"RHO GTPases Activate Formins";"Human cytomegalovirus infection";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_014091475.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014091122.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014090523.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014098373.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089529.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014095268.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_014093254.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_014085789.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" XP_014097058.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014103466.1 57 Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870 "G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Downstream TCR signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins" XP_014099012.1 19 MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6969 "TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_014089807.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014103429.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014100570.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014095958.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014093524.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014097613.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014099875.1 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_014092066.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_014092242.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" XP_014102464.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_014086631.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_014099204.1 10 Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-2514853 "Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Synthesis of PC";"WNT mediated activation of DVL";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes" XP_014088708.1 9 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Other glycan degradation" XP_014099042.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_014088038.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_014087284.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_014099460.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events" XP_014097021.1 20 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-163765;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5537;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8 "C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"ChREBP activates metabolic gene expression";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Mitochondrial protein import";"Reductive TCA cycle II";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes" XP_014097929.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_014097287.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577 "Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21" XP_014099717.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_014099338.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_014090033.1 7 MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-196757 "Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines" XP_014092267.1 4 MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;Reactome: R-HSA-1614558 "Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Degradation of cysteine and homocysteine" XP_014102159.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_014091589.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014089846.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_014099788.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014100305.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_014093943.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014090452.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014093115.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014091031.1 6 MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-7238;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1 "Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Sucrose biosynthesis II";"Starch degradation V";"Starch and sucrose metabolism" XP_014094972.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_014102783.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_014094971.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014089805.1 57 Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5678895;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-69017 "Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Hedgehog 'on' state";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of AXIN";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" XP_014095008.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_014092513.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_014085909.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_014086867.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014093401.1 8 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Activation of RAC1";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_014086940.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014086253.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_014090546.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_014102461.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_014097943.1 32 Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167287;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167290 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"HIV elongation arrest and recovery";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation" XP_014102595.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_014096528.1 4 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" XP_014100817.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_014101284.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014094995.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014089266.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_014098741.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014096191.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1" XP_014088680.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014098530.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_014100404.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_014098197.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099935.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014099020.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_014097319.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Complex I biogenesis";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_014093822.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014095984.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"O-linked glycosylation";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs" XP_014085194.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_014098455.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014086265.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014101893.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_014103112.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014086266.1 14 Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-7409 "Acyl chain remodelling of PC";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_014098692.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)" XP_014087234.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014092169.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Regulation of PLK1 Activity at G2/M Transition" XP_014092449.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014089283.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_014095978.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_014094789.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_014092594.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117 "Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_014092193.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_014100387.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_014085349.1 18 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I" XP_014087130.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_014092750.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-156827 "ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014096029.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_014088624.1 19 MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-983168;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Antigen processing: Ubiquitination & Proteasome degradation";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC" XP_014090441.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014091359.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014091427.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337 "(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_014102554.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014093882.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014103228.1 5 Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109 "Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis" XP_014088809.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_014096131.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014091112.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_014100151.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014094632.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014089874.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_014086561.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014097549.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014097457.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_014088855.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014086876.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_014092316.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" NP_957747.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014087210.1 9 Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68949 "CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin" XP_014086984.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014092693.1 15 Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-176034;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Interactions of Tat with host cellular proteins";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex" XP_014102392.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_014102760.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014098731.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014100274.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_014087745.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_014092660.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014088783.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_014100227.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_014091933.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014085463.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014090578.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014086580.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014098110.1 15 MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-7218 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_014097553.1 40 Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-5578749;Reactome: R-HSA-76042 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"FGFR2 alternative splicing";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014098035.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014100920.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_014093884.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014095487.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_014090468.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014089921.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014094679.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014090191.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854 "O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis" XP_014093646.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014098148.1 5 MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_014092607.1 9 MetaCyc: PWY-7902;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-6118;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94 "Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_014094230.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014102498.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014094893.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy" XP_014085709.1 23 Reactome: R-HSA-420092;Reactome: R-HSA-8964315;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-4086398;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-392451;Reactome: R-HSA-202040 "Glucagon-type ligand receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"Ca2+ pathway";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G-protein activation" XP_014088138.1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-190840 "MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HCMV Early Events";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_014097588.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_014087177.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014087376.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014088068.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_014098962.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014097417.1 29 MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-6333;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-5082;MetaCyc: PWY-5751;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5079;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;KEGG: 00592+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-7111;MetaCyc: PWY-5057;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00626+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-6342;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-5078;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00625+1.1.1.1 "Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"Acetaldehyde biosynthesis I";"L-leucine degradation III";"Salidroside biosynthesis";"L-methionine degradation III";"Phenylethanol biosynthesis";"Tyrosine metabolism";"Pyruvate fermentation to ethanol I";"Fatty acid degradation";"Pyruvate fermentation to ethanol II";"L-phenylalanine degradation III";"Chitin degradation to ethanol";"Retinol metabolism";"alpha-Linolenic acid metabolism";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to isobutanol (engineered)";"L-valine degradation II";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Naphthalene degradation";"L-tryptophan degradation V (side chain pathway)";"Noradrenaline and adrenaline degradation";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"L-isoleucine degradation II";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Chloroalkane and chloroalkene degradation" XP_014093210.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014098478.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014099226.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_014095329.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_014097586.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014094693.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014092640.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_014085527.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-442720;Reactome: R-HSA-180024 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events" XP_014099916.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_014103167.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014099846.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_014094372.1 18 MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Novobiocin biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism" XP_014099215.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_014085765.1 40 Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-167200;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418 "FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex" XP_014086272.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098926.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_014100152.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014090513.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_014097082.1 4 Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" XP_014089179.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_014095494.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014093662.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014088845.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014094883.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;MetaCyc: PWY-8051;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-4419969 "Anandamide biosynthesis II";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina" XP_014096869.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014088735.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014097969.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092688.1 7 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)" XP_014102383.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014086159.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014090959.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014092190.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_014091891.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-5340588;Reactome: R-HSA-4086398;Reactome: R-HSA-8856828;Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-5099900;Reactome: R-HSA-4641263 "Cargo recognition for clathrin-mediated endocytosis";"RNF mutants show enhanced WNT signaling and proliferation";"Ca2+ pathway";"Clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination" XP_014087022.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_014097721.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231 "Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_014089425.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" XP_014095164.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014101645.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_014089082.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12 "Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_014094714.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014089689.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014098826.1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" XP_014094249.1 3 MetaCyc: PWY-0;KEGG: 00330+2.3.1.57;MetaCyc: PWY-6117 "Putrescine degradation III";"Arginine and proline metabolism";"Spermine and spermidine degradation I" XP_014092496.1 6 Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling";"Negative regulation of MAPK pathway" XP_014100684.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014102377.1 34 Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648 "RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes" XP_014091351.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014085640.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014092245.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-1257604 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling" XP_014097419.1 29 MetaCyc: PWY-5082;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5751;MetaCyc: PWY-7396;MetaCyc: PWY-5076;MetaCyc: PWY-6802;MetaCyc: PWY-6313;MetaCyc: PWY-6333;MetaCyc: PWY-7111;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5486;MetaCyc: PWY-5079;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5480;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00830+1.1.1.1;MetaCyc: PWY-3162;KEGG: 00626+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00010+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-7013;KEGG: 00982+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-6342;MetaCyc: PWY-5078 "L-methionine degradation III";"Tyrosine metabolism";"Phenylethanol biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"L-leucine degradation III";"Salidroside biosynthesis";"Serotonin degradation";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to isobutanol (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol II";"L-phenylalanine degradation III";"Fatty acid degradation";"Pyruvate fermentation to ethanol I";"alpha-Linolenic acid metabolism";"Chitin degradation to ethanol";"Retinol metabolism";"L-tryptophan degradation V (side chain pathway)";"Naphthalene degradation";"Glycine, serine and threonine metabolism";"Glycolysis / Gluconeogenesis";"L-valine degradation II";"Chloroalkane and chloroalkene degradation";"3-methylbutanol biosynthesis (engineered)";"(S)-propane-1,2-diol degradation";"Drug metabolism - cytochrome P450";"Pyruvate fermentation to ethanol III";"Noradrenaline and adrenaline degradation";"L-isoleucine degradation II" XP_014103249.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014085598.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656 "G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry" XP_014086718.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_014085913.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041 "Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_014097022.1 19 KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-5172;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392 "Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Reductive TCA cycle II" XP_014100974.1 5 MetaCyc: PWY-6906;MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_014096498.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014087980.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_014094786.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014097277.1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_014089815.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014094061.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Intraflagellar transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Aggrephagy";"Macroautophagy";"HCMV Early Events";"COPI-mediated anterograde transport" XP_014088142.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014092690.1 15 Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200 "RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014088787.1 13 MetaCyc: PWY-7533;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-156590;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1 "Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione metabolism" XP_014090625.1 2 Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14 "Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis" XP_014097109.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_014088816.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014102565.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014093886.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014100429.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_014088440.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014095930.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_014098672.1 24 Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-4420097;Reactome: R-HSA-8963896;Reactome: R-HSA-111931;Reactome: R-HSA-163615;Reactome: R-HSA-163560;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-983231;Reactome: R-HSA-5610785;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;Reactome: R-HSA-442720;Reactome: R-HSA-5610783 "RET signaling";"Rap1 signalling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"VEGFA-VEGFR2 Pathway";"HDL assembly";"PKA-mediated phosphorylation of CREB";"PKA activation";"Triglyceride catabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"Factors involved in megakaryocyte development and platelet production";"GLI3 is processed to GLI3R by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI2 by the proteasome" XP_014089595.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014098695.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_014096469.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014095381.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014085655.1 6 KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_014094906.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_014093740.1 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014089492.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014093035.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_014099200.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-3371453 "PERK regulates gene expression";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response" XP_014096319.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014097836.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014090471.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014100001.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_014092538.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014099551.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014101430.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014103076.1 17 MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-6608;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00240+2.4.2.1 "Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Pyrimidine metabolism" XP_014088678.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014085412.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_014096333.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014085914.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014088638.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_014087629.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_014101587.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014095927.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014096435.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014092071.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_014096218.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_014093764.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" XP_014090494.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014102883.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014099038.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_014094383.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_014090217.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014103321.1 22 MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7727;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6958;MetaCyc: PWY-7049 "Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" XP_014099425.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_014097349.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_014102399.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_014098798.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014093243.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007 "DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"p38MAPK events" XP_014096262.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014093093.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_014092415.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014090936.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014092366.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_014089579.1 58 Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5689901;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-68827 "Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Hedgehog 'on' state";"Metalloprotease DUBs";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex" XP_014087079.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_014098015.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_014096219.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014092378.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199 "Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation" XP_014099163.1 6 Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922 "Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I" XP_014101478.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_014101238.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014097142.1 29 Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-5685942;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-349425;Reactome: R-HSA-912446;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-6803207;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693548;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway";"Processing of DNA double-strand break ends";"mTOR signaling pathway";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"HDR through Homologous Recombination (HRR)";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Autodegradation of the E3 ubiquitin ligase COP1";"Meiotic recombination";"Human cytomegalovirus infection";"Stabilization of p53";"TP53 Regulates Transcription of Caspase Activators and Caspases";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Regulation of TP53 Activity through Methylation";"Sensing of DNA Double Strand Breaks";"Thermogenesis";"Regulation of HSF1-mediated heat shock response" XP_014090144.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014092018.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014085750.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-9014325;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-168638 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NOD1/2 Signaling Pathway" XP_014098337.1 4 Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism" XP_014103086.1 13 KEGG: 00640+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7118;Reactome: R-HSA-71384;MetaCyc: PWY-5108;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132 "Propanoate metabolism";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol";"Ethanol oxidation";"L-isoleucine biosynthesis V";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Lupulone and humulone biosynthesis" XP_014093223.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_014101022.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_014099912.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092802.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" XP_014095858.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014086682.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_014099166.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014099785.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_014096048.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4 "Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Purine metabolism" XP_014096999.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_014103738.1 14 MetaCyc: PWY-5057;MetaCyc: PWY-5104;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5101;Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42 "L-valine degradation II";"L-isoleucine biosynthesis IV";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis II";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis" XP_014099170.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014099987.1 17 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7176 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"UTP and CTP de novo biosynthesis" XP_014103678.1 5 MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757 "Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines" XP_014086140.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014102580.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_014088198.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_014099258.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014098679.1 24 Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-392517;Reactome: R-HSA-8853659;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-381676;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-163358;Reactome: R-HSA-442720;Reactome: R-HSA-5610783 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"Rap1 signalling";"RET signaling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA-mediated phosphorylation of CREB";"HDL assembly";"Triglyceride catabolism";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Degradation of GLI2 by the proteasome" XP_014093661.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_014088431.1 18 Reactome: R-HSA-204174;MetaCyc: PWY-5046;Reactome: R-HSA-70268;MetaCyc: PWY-5084;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00010+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00020+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00620+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-70895 "Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glycine, serine and threonine metabolism";"Citric acid cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Pyruvate metabolism";"Lysine degradation";"Propanoate metabolism";"Lysine catabolism";"Branched-chain amino acid catabolism" XP_014092788.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_014086333.1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" XP_014094780.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014086073.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014096831.1 5 MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism" XP_014102172.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_014101777.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_014097767.1 13 KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497 "Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"Folate polyglutamylation";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)" XP_014103629.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5744;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5743 "Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"3-hydroxypropanoate cycle" XP_014091544.1 12 KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108 "Methane metabolism";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V" XP_014103048.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014094054.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_014101174.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_014090219.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_014098389.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_014088094.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_014102717.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014086754.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014096154.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits" XP_014093387.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_014101253.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014094546.1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis" NP_957753.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014099960.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098625.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014092058.1 5 Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling" XP_014101969.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_014096103.1 16 Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript" XP_014086964.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014096454.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014090288.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_014087941.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014099808.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_014103540.1 12 KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-2821;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-601;MetaCyc: PWY-7901;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187 "Cysteine and methionine metabolism";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from tyrosine";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine" XP_014092791.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014087421.1 28 Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-5656121;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5358606;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-6804756;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5696395;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-3371511;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLI";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Regulation of TP53 Activity through Phosphorylation";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Formation of Incision Complex in GG-NER";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HSF1 activation";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway" XP_014089059.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014092269.1 4 Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism" XP_014088684.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_014095566.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_014103110.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014089898.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_014102474.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014096533.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014091412.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_014102138.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014092241.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_014095450.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014097055.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_014091492.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014102472.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014102858.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_014091945.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_014097592.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096718.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_014096187.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787 "Activation of SMO";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Hedgehog 'off' state" XP_014099147.1 11 KEGG: 00520+5.3.1.8;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-3861;MetaCyc: PWY-6992;MetaCyc: PWY-3881;MetaCyc: PWY-7586 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_014102651.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_014095291.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014095642.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014092141.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014095542.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_014101730.1 12 Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Rho GTPase cycle";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK" XP_014088664.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014085296.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095287.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_014098803.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_014091372.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014098262.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_014090859.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014097008.1 4 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_014101406.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014091430.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_014091846.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_014103464.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-174113 "APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1" XP_014101779.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014101107.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_014086673.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_014103735.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_014094083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014086891.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_014103496.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014088750.1 14 Reactome: R-HSA-9033241;MetaCyc: PWY-8051;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.42;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-75896;MetaCyc: PWY-8055;MetaCyc: PWY-5667 "Peroxisomal protein import";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I" XP_014087275.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_014091087.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014101265.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014095482.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_014085326.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014087797.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014096198.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_014098690.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_014096302.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656 "Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling" XP_014099208.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-170822 "Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_014089763.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6811438 "RAB geranylgeranylation";"Intra-Golgi traffic" XP_014087678.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014097071.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736 "Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"RAF activation";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors" XP_014091842.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_014092328.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_014091131.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014091406.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014095017.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_014090434.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087532.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_014098041.1 6 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling" XP_014086785.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_014086003.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_014090658.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_014091418.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_014089649.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Dual Incision in GG-NER" XP_014096592.1 7 Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7841;MetaCyc: PWY-7838;MetaCyc: PWY-7836;MetaCyc: PWY-7839;MetaCyc: PWY-5129 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)" XP_014092763.1 24 Reactome: R-HSA-5625740;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218921;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-202424;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764 "RHO GTPases activate PKNs";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"Integrin signaling";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated cell proliferation";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Downstream TCR signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"Activation of AKT2";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"RSK activation";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling" XP_014089437.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_014094259.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014088147.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014089265.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_014094028.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014090153.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_014085219.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_014087490.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_014097113.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_014091408.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_014097555.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport" XP_014091180.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_014089313.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014098350.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014100130.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014096536.1 5 MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122 "5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II" XP_014088009.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099145.1 10 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-451308;Reactome: R-HSA-442982;Reactome: R-HSA-9620244 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"RAF/MAP kinase cascade";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation" XP_014102458.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014094207.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014093953.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014097395.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086529.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014097794.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014094070.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828 "Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis" XP_014098642.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014093633.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014100879.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014088862.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_014098509.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014103586.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014093443.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" XP_014094215.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014090990.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport" XP_014101564.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096071.1 10 MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines" XP_014092559.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_014091100.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014097762.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014103281.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis" XP_014098184.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_014095269.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_014102695.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_014089281.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014092910.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_014100659.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014093392.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014088796.1 13 Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916 "Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation" XP_014097307.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_014098901.1 13 KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662 "Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Rho GTPase cycle";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"MAPK6/MAPK4 signaling";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK";"G alpha (q) signalling events";"Thermogenesis";"EPHB-mediated forward signaling" XP_014095160.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014093055.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis" XP_014091581.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014098365.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097529.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014089184.1 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism" XP_014094989.1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" XP_014092244.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400 "PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer" XP_014092480.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_014101350.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_014087944.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014086746.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-204174;Reactome: R-HSA-8963684 "Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism" XP_014087725.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014093159.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014088523.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_014098708.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014091706.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_014087241.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014097199.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76042 "RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014103452.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_014094836.1 7 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1268020 "Oxidative phosphorylation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Photosynthesis";"Mitochondrial protein import" XP_014089847.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_014103525.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_014095266.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_014096980.1 42 MetaCyc: PWY-7654;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-7778;MetaCyc: PWY-7401;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-6944;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6883;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7656;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6863;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-1361 "(8E,10E)-dodeca-8,10-dienol biosynthesis";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"2-methylpropene degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Androstenedione degradation";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to butanol II (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Fatty acid salvage";"Butanoate metabolism";"Aminobenzoate degradation";"beta-Alanine metabolism";"Toluene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid elongation";"Tryptophan metabolism";"alpha-Linolenic acid metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)" XP_014091802.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014089801.1 10 MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8055 "Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_014091994.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_014088873.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_014098217.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_014094304.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_014092665.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_014098895.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014101644.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014086796.1 8 KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014103066.1 13 MetaCyc: PWY-7226;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7198 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_014095782.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014093418.1 13 Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8856828 "Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis" XP_014099464.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_014094919.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014101534.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092680.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014101869.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014095592.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014100820.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014093850.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_014085635.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014098921.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_014093419.1 13 Reactome: R-HSA-3928665;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828 "EPH-ephrin mediated repulsion of cells";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"LDL clearance";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis" XP_014088738.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014085435.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014099892.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014102299.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_014091793.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis" XP_014093689.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014094049.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014102515.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014087525.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014092344.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014096081.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978 "Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production" XP_014097254.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014094008.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_014093292.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_014087766.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014096004.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "Neutrophil degranulation";"Glycosphingolipid metabolism" XP_014085305.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014088125.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_014090289.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_014092054.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_014097258.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_014096532.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_014101090.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014099260.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014088237.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014092536.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014085216.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-176412 "Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C" XP_014094046.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014103526.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_014102517.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014090009.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_014087056.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014093400.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" XP_014102085.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014098917.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014103666.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014094303.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_014103485.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014095567.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion" XP_014093092.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_014087531.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014088275.1 4 MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-7383 "Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_014100281.1 8 Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Ion channel transport";"Photosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_014103057.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014095822.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_014103727.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014092922.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_014096681.1 42 Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-8939236;Reactome: R-HSA-1221632;Reactome: R-HSA-427359;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-2559582;Reactome: R-HSA-2299718;Reactome: R-HSA-5625886;Reactome: R-HSA-3214858;Reactome: R-HSA-2559580;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-5334118;Reactome: R-HSA-9616222;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-427389;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-977225;Reactome: R-HSA-5250924;Reactome: R-HSA-5693565;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-5578749;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-606279;Reactome: R-HSA-912446 "SUMOylation of chromatin organization proteins";"HATs acetylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic synapsis";"SIRT1 negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Senescence-Associated Secretory Phenotype (SASP)";"Condensation of Prophase Chromosomes";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RMTs methylate histone arginines";"Oxidative Stress Induced Senescence";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"DNA methylation";"Transcriptional regulation of granulopoiesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HCMV Early Events";"PKMTs methylate histone lysines";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Amyloid fiber formation";"B-WICH complex positively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Transcriptional regulation by small RNAs";"HDACs deacetylate histones";"HCMV Late Events";"Deposition of new CENPA-containing nucleosomes at the centromere";"Meiotic recombination" XP_014093263.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_014090208.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_014086045.1 10 KEGG: 00670+2.1.1.45;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7184;MetaCyc: PWY-7199;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7187 "One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_014102419.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_014095181.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014100278.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_014089457.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_014100849.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014085399.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014099162.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_014102387.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014097538.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_014092028.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_014099213.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" XP_014096633.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_014093365.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014091459.1 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7338;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;MetaCyc: PWY-7858 "Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II" XP_014098052.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" XP_014100379.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_014094433.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014092372.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_014103357.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014096744.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014096867.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_014086297.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_014090869.1 7 KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis";"Fructose and mannose metabolism" XP_014096924.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014085602.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_014085831.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_014103538.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014097898.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014089518.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014092270.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014090476.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_014091627.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014099423.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014093056.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_014100591.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040 "G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_014103408.1 10 Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_014086798.1 8 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014092013.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014091343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014088861.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_014088230.1 8 Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1 "Glycolysis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis" XP_014086675.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_014091347.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_014091130.1 6 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Biotin transport and metabolism" XP_014098246.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_014090406.1 7 KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16 "Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_014085342.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_014099466.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_014093224.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014103306.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_014096561.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-4261;Reactome: R-HSA-1483166 "Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Synthesis of PA" XP_014099865.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014087463.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_014087832.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716 "EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_014087530.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014090977.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_014092339.1 3 MetaCyc: PWY-5697;MetaCyc: PWY-5698;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Purine metabolism" XP_014088852.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014091814.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_014095221.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014097303.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" XP_014085767.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system" XP_014090551.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids" XP_014091105.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_014090445.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-8955332 "Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Kinesins";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin" XP_014093247.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014085358.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014092268.1 4 Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism" XP_014093613.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014092586.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014090780.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_014103512.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_014087868.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_014097803.1 6 KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23 "Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Other glycan degradation" XP_014097261.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014099168.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_014092551.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014086513.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014093487.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_014100087.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_014087749.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_014089124.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014086549.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014085584.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism" XP_014092384.1 6 MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11 "Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" XP_014088195.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_014096059.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_014086628.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014090534.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014088211.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014085327.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014093227.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014103341.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014090533.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" NP_957746.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014092530.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167200 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_014102134.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" XP_014099007.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014088774.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014087958.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_014092975.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_014090043.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_014087732.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_014096374.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014102226.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180534 "MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4" XP_014097957.1 7 Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580 "Transcriptional Regulation by E2F6";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence" XP_014097469.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_014088906.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014102688.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014099919.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_014086186.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_014093605.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014094177.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_014087829.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-5358749;Reactome: R-HSA-432142 "S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL" XP_014097897.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859 "Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly" XP_014096361.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_014096553.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8856828;Reactome: R-HSA-8875656 "TBC/RABGAPs";"Clathrin-mediated endocytosis";"MET receptor recycling" XP_014089893.1 6 MetaCyc: PWY-5668;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;Reactome: R-HSA-1483166;MetaCyc: PWY-7817 "Cardiolipin biosynthesis I";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Synthesis of PA";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_014093103.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014086685.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_014101589.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039 "Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex" XP_014095647.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014090437.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_014102691.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014097043.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_014097752.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_014099874.1 19 MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;Reactome: R-HSA-163765;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00020+2.3.3.8;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5 "Reductive TCA cycle II";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes" XP_014098710.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014095126.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_014100275.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_014094688.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014098376.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014086170.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_014097912.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_014097548.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014093367.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_014093028.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_014093350.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_014085631.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_014101986.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014095545.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014095799.1 7 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-3000170;Reactome: R-HSA-373753;MetaCyc: PWY-7221;Reactome: R-HSA-212676;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Syndecan interactions";"Nephrin family interactions";"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins" XP_014086239.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014098599.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014093359.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014091204.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_014089850.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_014090000.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_014097718.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772 "Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling" XP_014092860.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_014102943.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation" XP_014103737.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_014087647.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014097590.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014086416.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_014086059.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_014103250.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014100430.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_014090536.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014103236.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_014093737.1 6 Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis" XP_014101858.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014095713.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_014089559.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_014090509.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_014096896.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_014102311.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014091761.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099954.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014098960.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_014093116.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014085138.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014097945.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014095401.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_014093796.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014101125.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014093922.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014098239.1 7 MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation" XP_014099992.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014090957.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_014099199.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-3371453 "SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response" XP_014095366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014092002.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-5656169 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Termination of translesion DNA synthesis" XP_014097195.1 20 MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-735 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis" XP_014085443.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_014102988.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014100353.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_014097001.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_014089596.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014101172.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095561.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014091491.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014092122.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5685939 "HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"HDR through MMEJ (alt-NHEJ)" XP_014088538.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014092172.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling" XP_014100526.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014097455.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_014099727.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_014099033.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_014101700.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014094779.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014088529.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_014088000.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_014102386.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014091713.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_014097992.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_014101487.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_014097550.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_014086335.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014103335.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_014092764.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014085856.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014101501.1 19 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-3214858;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"RMTs methylate histone arginines";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_014095246.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_014100212.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014098023.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_014093121.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_014094260.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_014102379.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014092834.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014095745.1 13 Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52 "CS/DS degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis" XP_014093577.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_014099678.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014097201.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-735;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6 "(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation" XP_014090548.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_014086609.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_014099072.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_014096384.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014100635.1 8 Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1 "Urea cycle";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_014092870.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014099283.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014092639.1 12 Reactome: R-HSA-1251985;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-205043 "Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus" XP_014092433.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014091667.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_014102657.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_014092608.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_014093508.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_014093213.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684 "Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state" XP_014089975.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014097547.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014099740.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_014085526.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014085177.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014102859.1 16 Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-3134963;Reactome: R-HSA-1257604;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-209543;Reactome: R-HSA-975138;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-5602680;Reactome: R-HSA-975110;Reactome: R-HSA-166058;Reactome: R-HSA-975155 "ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PIP3 activates AKT signaling";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"MyD88 deficiency (TLR5)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome" XP_014096331.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014103604.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014098438.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_014096152.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72695 "Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex" XP_014091915.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014096344.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_014092156.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-170660 "Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway" XP_014086749.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_014093054.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_014100384.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014091799.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-6433 "Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)" XP_014088966.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014092416.1 12 Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-75893 "Growth hormone receptor signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"TNF signaling" XP_014098533.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014097701.1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-936440 "Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" XP_014089585.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014087666.1 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6122 "Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_014099384.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014087097.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014090375.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014097515.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632 "Separation of Sister Chromatids";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Meiotic synapsis" XP_014092353.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_014097556.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_014094881.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_014102146.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" XP_014101364.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014103731.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_014103598.1 6 KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17 "Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism" XP_014099134.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014100326.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_014094419.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_014088709.1 9 KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52 "Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation" NP_957752.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014085636.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014103664.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014096377.1 29 Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6781823 "Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of TC-NER Pre-Incision Complex" XP_014087162.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014094892.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" XP_014103420.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014096778.1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_014089545.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_014102421.1 3 Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import" XP_014092751.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-975957 "mTORC1-mediated signalling";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014091365.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014090835.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_014099507.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014099933.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_014093353.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014093824.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014091319.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014096214.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014103063.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014101839.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096052.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_014098183.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_014088339.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_014087122.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014088029.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_014095130.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-4641258;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702 "Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Degradation of DVL";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling" XP_014100023.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_014088267.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014088959.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014089216.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" NP_957743.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014095026.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_014093704.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014097304.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_014089851.1 9 MetaCyc: PWY-5744;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_014097386.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014098175.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014092754.1 12 Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014091269.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014087126.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_014085809.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_014103049.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-6782315 "Methylation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"tRNA modification in the nucleus and cytosol" XP_014095800.1 7 Reactome: R-HSA-212676;Reactome: R-HSA-6794361;MetaCyc: PWY-7221;Reactome: R-HSA-3000170;Reactome: R-HSA-373753;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8 "Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Guanosine ribonucleotides de novo biosynthesis";"Syndecan interactions";"Nephrin family interactions";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism" XP_014098260.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_014095718.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_014090426.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014095131.1 56 Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1234176;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664 "Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Downstream TCR signaling";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation" XP_014103443.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_014098872.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014089794.1 11 MetaCyc: PWY-7102;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7560 "Bisabolene biosynthesis (engineered)";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II" XP_014103230.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_014094250.1 3 MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57;MetaCyc: PWY-0 "Spermine and spermidine degradation I";"Arginine and proline metabolism";"Putrescine degradation III" XP_014101091.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086995.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014102370.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_014099821.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_014097206.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_014103197.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014101875.1 13 Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-2206308;Reactome: R-HSA-1660662;MetaCyc: PWY-6807 "Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Neutrophil degranulation";"MPS IV - Morquio syndrome B";"Glycosphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)" XP_014102241.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_014091433.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-9018519;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Estrogen-dependent gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock" XP_014099481.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27 "Cysteine and methionine metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" XP_014089953.1 8 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1 "Purine salvage";"Purine metabolism";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II" XP_014086026.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014098566.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014103772.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_014092385.1 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism" XP_014085536.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-432040 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_014087004.1 57 Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-180534 "Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Hedgehog 'on' state";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Degradation of DVL";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4" XP_014089282.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014085350.1 18 MetaCyc: PWY-7417;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788 "Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC" XP_014103394.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_014102145.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014096712.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472 "Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_014087835.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5339716 "EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Misspliced GSK3beta mutants stabilize beta-catenin" XP_014086424.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092313.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014098664.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014102497.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_014102219.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_014089126.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_014095301.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_014093106.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014099181.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_014099853.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_014090197.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_014085880.1 4 Reactome: R-HSA-1614558;KEGG: 00920+2.8.1.1;MetaCyc: PWY-5350;MetaCyc: PWY-7927 "Degradation of cysteine and homocysteine";"Sulfur metabolism";"Thiosulfate disproportionation IV (rhodanese)";"Sulfide oxidation IV (mitochondria)" XP_014088369.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_014087246.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_014090433.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087867.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014090615.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_014098532.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014093171.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" XP_014097024.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_014093098.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_014090032.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014089796.1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-3928665 "Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells" XP_014092494.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_014087679.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014097162.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Viral Messenger RNA Synthesis";"HCMV Early Events";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion" XP_014089392.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_014099426.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_014098518.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014095388.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014095747.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014100313.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014089027.1 4 Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE" XP_014098972.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014095279.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014088668.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_014090949.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_014092957.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_014101358.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014086411.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-2467813;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751 "Degradation of AXIN";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"Separation of Sister Chromatids";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity" XP_014091993.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_014097716.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014097720.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-982772 "Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Growth hormone receptor signaling" XP_014102121.1 5 Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766;MetaCyc: PWY-5531;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_014101379.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_014087848.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_014099773.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_014087850.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014103309.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_014090549.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014100466.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014102063.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_014098182.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_014100786.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014100890.1 4 Reactome: R-HSA-422085;KEGG: 00564+3.1.1.7;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Glycerophospholipid metabolism";"Synthesis of PC";"Neurotransmitter clearance" XP_014094864.1 26 Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-389977 "The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Kinesins";"RHO GTPases Activate Formins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway" XP_014103412.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-200425 "TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carnitine metabolism" XP_014093216.1 22 Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_014096031.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_014087852.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_014098367.1 6 KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234 "One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" XP_014087775.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_014093460.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412 "Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C" XP_014093361.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014095528.1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082 "Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression" XP_014089016.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014097242.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_014090979.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_014086871.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_014090766.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014099523.1 7 MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7184;KEGG: 00730+3.6.1.15 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Thiamine metabolism" XP_014091768.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_014092579.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis" XP_014099839.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014085675.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_014099609.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014093032.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014094583.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895 "ATF4 activates genes in response to endoplasmic reticulum stress";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency" XP_014097872.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014095115.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_014090178.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087185.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_014097364.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014090712.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding" XP_014094519.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_014096348.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014092003.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014098101.1 6 Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52 "Serine biosynthesis";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism" XP_014098952.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" XP_014102448.1 1 MetaCyc: PWY-6938 "NADH repair" XP_014088864.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_014094198.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014091071.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_014101005.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014100831.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_014089297.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_014102462.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_014103682.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_014093861.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014085960.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_014087601.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_014094495.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_014090614.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_014088736.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014095093.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_014086299.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_014085524.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-901032;MetaCyc: PWY-7511 "XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination" XP_014094428.1 5 MetaCyc: PWY-7919;Reactome: R-HSA-4793954;Reactome: R-HSA-532668;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918 "Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)" XP_014097256.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014097334.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014094631.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014089390.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_014093647.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014092263.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014101028.1 7 Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes" XP_014097882.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014089867.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014088944.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_014089677.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014100809.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014091414.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014100159.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014091554.1 26 Reactome: R-HSA-1234158;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-5617472;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Attenuation phase";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_014092375.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" XP_014087054.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" XP_014100312.1 6 MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_014100021.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014091008.1 10 Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-111457 "Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria" XP_014086066.1 14 Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279 "Respiratory electron transport";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)" XP_014092948.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014095116.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014089056.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_014087571.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_014091535.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex" XP_014100704.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-8876198 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_014090746.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-3371453 "SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Late Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response" XP_014093591.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580 "Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Oncogene Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence" XP_014094286.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_014091533.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_014102110.1 40 KEGG: 00627+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7656;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-1361;MetaCyc: PWY-6863;MetaCyc: PWY-6583;KEGG: 00360+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-7401;MetaCyc: PWY-7778;MetaCyc: PWY-7654;MetaCyc: PWY-7216;MetaCyc: PWY-7007;MetaCyc: PWY-5109;MetaCyc: PWY-7726;KEGG: 00640+4.2.1.17;MetaCyc: PWY-6945;MetaCyc: PWY-6944;MetaCyc: PWY-5789;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-6883;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-7094;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35 "Aminobenzoate degradation";"beta-Alanine metabolism";"Toluene degradation";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid elongation";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Caprolactam degradation";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol I";"Phenylalanine metabolism";"Methyl tert-butyl ether degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to butanol II (engineered)";"Lysine degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid salvage";"Fatty acid degradation";"Benzoate degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation" XP_014094084.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014095748.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_014103668.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_014103436.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" XP_014091367.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014088946.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014091121.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_014089183.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_014090980.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684 "Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state" XP_014099247.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014089915.1 13 MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5538 "TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI" XP_014089194.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_014093239.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014100154.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" XP_014097726.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_014085632.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_014085335.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_014086154.1 6 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-1268020 "ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import" XP_014093634.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014101973.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014096871.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014086838.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014085844.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014093589.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700 "Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_014099098.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014097441.1 4 Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4 "Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Tryptophan metabolism" XP_014090540.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_014100707.1 15 Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571 "HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)" XP_014102888.1 6 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_014099669.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_014088844.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_014091363.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_014098393.1 22 MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-6958;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7727;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7053;MetaCyc: PWY-7592;MetaCyc: PWY-7726 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_014092916.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_014086677.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_014098703.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086733.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events" XP_014090430.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014097445.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_014102653.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014100265.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014092947.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014086122.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_014087869.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events" XP_014096422.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087076.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048 "APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_014093389.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014098253.1 4 Reactome: R-HSA-5661270;MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30 "Formation of xylulose-5-phosphate";"Glycerol degradation I";"Pentose and glucuronate interconversions";"Glycerolipid metabolism" XP_014092276.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014087198.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014098547.1 8 KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_014096950.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6527;MetaCyc: PWY-6397;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2 "Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism" XP_014087746.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_014094505.1 6 KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;Reactome: R-HSA-913709 "Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins" XP_014103377.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014093357.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation" XP_014093391.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014102390.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_014090947.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014095850.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_014097134.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_014099529.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014102173.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_014085431.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014091488.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014098445.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_014089195.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_014088631.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_014089072.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014088902.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014089646.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014088707.1 9 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series" XP_014092830.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014090845.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_014091734.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014093543.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_014091553.1 26 Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-3899300;Reactome: R-HSA-201722 "Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex" XP_014093825.1 34 Reactome: R-HSA-9639288;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Amino acids regulate mTORC1";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"HCMV Early Events" XP_014089888.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_014087039.1 4 KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage" XP_014093906.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096688.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014094866.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014094858.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_014090243.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_014091999.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014094721.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014095606.1 17 Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-983168 "Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Neddylation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014088126.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_014090031.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_014089991.1 8 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-7179;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1 "Purine salvage";"Purine metabolism";"Neutrophil degranulation";"Surfactant metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II" XP_014094072.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_014100540.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014103330.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_014102398.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription" XP_014088930.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_014094857.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_014090948.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014093281.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014091828.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014087959.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_014090694.1 4 KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis" XP_014098018.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014090187.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-7254;Reactome: R-HSA-71403;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-6728 "Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Methylaspartate cycle" XP_014096931.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014088759.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014099906.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2173796;Reactome: R-HSA-210744;Reactome: R-HSA-1912408;Reactome: R-HSA-72163 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway" XP_014090204.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014091329.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_014095564.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_014100447.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24 "NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions";"p38MAPK events";"mTOR signaling pathway" XP_014103263.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_014093486.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_014085826.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_014097594.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014088509.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014094804.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014100741.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813 "The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"HCMV Early Events";"COPI-mediated anterograde transport";"Kinesins";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Separation of Sister Chromatids" XP_014093209.1 3 Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65 "Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism" XP_014097318.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Respiratory electron transport";"Complex I biogenesis" XP_014088149.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_014088743.1 19 MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-561;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728 "Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Pyruvate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Glyoxylate and dicarboxylate metabolism";"TCA cycle II (plants and fungi)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Methylaspartate cycle" XP_014094756.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" NP_957744.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014102135.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014089530.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014094642.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014102599.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_014102214.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014089624.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_014089005.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_014089651.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_014098677.1 24 Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-111931;Reactome: R-HSA-381676;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-4420097;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-5610785;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-163358;Reactome: R-HSA-5610783;Reactome: R-HSA-442720 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"RET signaling";"Rap1 signalling";"PKA activation";"PKA-mediated phosphorylation of CREB";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"HDL assembly";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"VEGFA-VEGFR2 Pathway";"DARPP-32 events";"mTOR signaling pathway";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"GLI3 is processed to GLI3R by the proteasome";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of key metabolic factors";"Degradation of GLI2 by the proteasome";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_014086800.1 8 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_014100541.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014088884.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662 "Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism" XP_014085223.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_014090389.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_014098450.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_014088016.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_014090436.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7602 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_014087088.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_014102553.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014102513.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014097723.1 4 Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552 "Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin" XP_014088937.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_014099034.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_014097033.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014103744.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014103047.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014093236.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014095464.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014103079.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209 "Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation" XP_014096138.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_014098900.1 31 MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-7663;MetaCyc: PWY-7664;MetaCyc: PWY-5971;MetaCyc: PWY-8049;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;MetaCyc: PWY-5966-1;MetaCyc: PWY-5973;MetaCyc: PWY-6282;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWY-8012;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-5989;MetaCyc: PWY-6519;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-5367;MetaCyc: PWY-7388;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWYG-321 "Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Mupirocin biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"8-amino-7-oxononanoate biosynthesis I";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Petroselinate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"" XP_014101163.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_014103728.1 7 Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis" XP_014102689.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014093177.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014085835.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_014093940.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014088005.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_014092759.1 24 Reactome: R-HSA-202424;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-444257;Reactome: R-HSA-114604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-354192;Reactome: R-HSA-5218920;Reactome: R-HSA-392451;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Downstream TCR signaling";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Activation of AKT2";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RSK activation";"GPVI-mediated activation cascade";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"Integrin signaling";"VEGFR2 mediated vascular permeability";"G beta:gamma signalling through PI3Kgamma";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_014090584.1 5 KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" XP_014087116.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_014096622.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_014100226.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_014092391.1 6 KEGG: 00010+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_014103307.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_014092776.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_014090652.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_014085549.1 4 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_014090760.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_014102546.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_014085790.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_014085885.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014097060.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014099209.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7433;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122 "O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis" XP_014086212.1 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_014093970.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_014085532.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_014090572.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014097329.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014086301.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_014097672.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014098451.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014093612.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014091759.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_014103085.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_014089957.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_014085728.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014095790.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_014092884.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_014093939.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014092345.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014099504.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095801.1 7 Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-3000170;Reactome: R-HSA-373753;MetaCyc: PWY-7221;Reactome: R-HSA-212676;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Syndecan interactions";"Nephrin family interactions";"Guanosine ribonucleotides de novo biosynthesis";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins" XP_014085217.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_014093007.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_014098026.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_014090518.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_014085357.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014099591.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" NP_957745.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014099268.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014094334.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014101693.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014085211.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593 "Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity" XP_014101705.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014090813.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" XP_014086551.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014098135.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014091641.1 8 Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_014085367.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_014091517.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_014096921.1 8 MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;Reactome: R-HSA-73614;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695 "Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation" XP_014088811.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167246 "RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_014103137.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_014089848.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091661.1 3 MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574 "Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_014089234.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_014090889.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" XP_014102315.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_014086285.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_014091821.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014095527.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock" XP_014094086.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087831.1 22 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase" XP_014091197.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827 "Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex" XP_014088355.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014085816.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_014102210.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014093905.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014095402.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_014103303.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014095480.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_014091370.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_014103487.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014096030.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_014095391.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_014098916.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_014092990.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014091515.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_014086552.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014086629.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_014091129.1 13 Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1 "Signaling downstream of RAS mutants";"Thermogenesis";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection" XP_014096855.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_014086292.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_014097337.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014103640.1 9 Reactome: R-HSA-3645790;Reactome: R-HSA-3642279;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532 "TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR1 KD Mutants in Cancer" XP_014086220.1 9 KEGG: 00513+2.4.1.141;MetaCyc: PWY-6385;MetaCyc: PWY-6470;Reactome: R-HSA-5633231;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;KEGG: 00550+2.4.1.227 "Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis" XP_014101664.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014090660.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_014088419.1 11 MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6549 "Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"L-glutamine biosynthesis III" XP_014093794.1 3 Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169 "HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis" XP_014097728.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_014090018.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_014093220.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025 "Misspliced GSK3beta mutants stabilize beta-catenin";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation" XP_014094412.1 4 Reactome: R-HSA-5368286;Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_014085355.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014099778.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014093860.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014087237.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014090393.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" XP_014094918.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014100575.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_014091863.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014093894.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014100025.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014095163.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014087244.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_014102137.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_014095414.1 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_014091127.1 13 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"Signaling downstream of RAS mutants";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Relaxin signaling pathway" XP_014100830.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_014090162.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_014097860.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_014089186.1 6 MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-6908;Reactome: R-HSA-196819 "Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism" XP_014090704.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014098189.1 3 Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17 "Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism" XP_014100819.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_014093167.1 5 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_014088128.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014093712.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014085328.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014086211.1 57 Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-9604323;Reactome: R-HSA-983168;Reactome: R-HSA-8852276;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780 "Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Negative regulation of NOTCH4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome" XP_014097536.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-177929;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_014088710.1 9 MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902 "Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)" XP_014095231.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_014089453.1 9 KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-6901;Reactome: R-HSA-70263;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484 "Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)" XP_014088118.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014092903.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_014093926.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014102378.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014094300.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014098794.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" XP_014097963.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-68827;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-2467813;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8939236;Reactome: R-HSA-180534 "Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"CDT1 association with the CDC6:ORC:origin complex";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Separation of Sister Chromatids";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4" XP_014085794.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_014090490.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825 "Neddylation";"UCH proteinases";"Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis" XP_014094736.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8055 "Synthesis of PA";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis" XP_014102189.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_014086910.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_014093352.1 3 MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368 "D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_014091161.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014101039.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014099187.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014085146.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_014089982.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014096303.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction" XP_014091489.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_014099361.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014085754.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014092681.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_014086574.1 8 MetaCyc: PWY-7400;MetaCyc: PWY-5;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4983;Reactome: R-HSA-70635;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5 "L-arginine biosynthesis IV (archaebacteria)";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Urea cycle";"Urea cycle";"Alanine, aspartate and glutamate metabolism" XP_014093347.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_014088724.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014102316.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014095601.1 5 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014102211.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025 "Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Kinesins";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"HCMV Early Events";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation" XP_014101114.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_014098146.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism" XP_014085696.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014098057.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_014098385.1 7 Reactome: R-HSA-171319;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-606279 "Telomere Extension By Telomerase";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_014093248.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014092388.1 6 KEGG: 00010+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00260+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484 "Glycolysis / Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycine, serine and threonine metabolism";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_014101082.1 11 KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00740+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9 "Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Riboflavin metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" XP_014089604.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_014090762.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_014103562.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_014097050.1 5 MetaCyc: PWY-7863;Reactome: R-HSA-196843;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;MetaCyc: PWY-6168 "Roseoflavin biosynthesis";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Flavin biosynthesis III (fungi)" XP_014085145.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014095338.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014101077.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_014101926.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014101754.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014094778.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014091255.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014091735.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_014085697.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_014089422.1 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" XP_014100185.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_014087265.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014087853.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_014099838.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_014088508.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_014085891.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-975138 "Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_014089235.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" XP_014092946.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014085899.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Negative regulation of MET activity";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_014093168.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_014102470.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_014101727.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_014095928.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014088357.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_014103726.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-6840;Reactome: R-HSA-5578999 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_014101855.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_014086353.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C" XP_014098145.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_014090096.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014091487.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_014087693.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014097775.1 3 MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_014088099.1 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853 "Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)" XP_014090198.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_014087346.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_014093833.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014092988.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_014101878.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014099671.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" XP_014097528.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014103451.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_014103003.1 6 Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.64+3.1.3.95;MetaCyc: PWY-6580;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368 "Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_014097673.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014098633.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_014085172.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014086548.1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)" XP_014093803.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014103773.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_014101018.1 6 KEGG: 00230+4.1.1.21;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+6.3.2.6;MetaCyc: PWY-7234 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" XP_014090772.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits" XP_014086810.1 10 Reactome: R-HSA-5419276;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-389661 "Mitochondrial translation termination";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Glyoxylate metabolism and glycine degradation" XP_014090276.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_014094235.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_014096120.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014090143.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014087786.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" XP_014093949.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_014102284.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014093715.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167242 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_014092709.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_014085660.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014100675.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014091407.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-983168;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68827;Reactome: R-HSA-8948751;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128 "Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of PTEN stability and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Hedgehog ligand biogenesis";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling" XP_014090763.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_014095521.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_014089648.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014089645.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014093670.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_014100971.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Neutrophil degranulation" XP_014096587.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7836;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-5129;MetaCyc: PWY-7839 "Globo-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis" XP_014103508.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_014090941.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580 "Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence" XP_014102640.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_014101871.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_014094581.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_014087841.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014085756.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014095787.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I" XP_014094531.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_014087225.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014091002.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation" XP_014100826.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_014095113.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_014102656.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_014087677.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014100539.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_014101037.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_014088313.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014099530.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_014097787.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_014097652.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_014085853.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_014102672.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_014090693.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_014085975.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_014091306.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_014097786.1 4 KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis" XP_014085209.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_014085676.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014096807.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"MAP2K and MAPK activation";"mTOR signalling" XP_014099679.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_014102600.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_014086997.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_014091556.1 26 Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-3134973;Reactome: R-HSA-5617472;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-400253 "Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"CD209 (DC-SIGN) signaling";"Attenuation phase";"Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"Circadian Clock" XP_014087167.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_014085957.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-7559;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13 "Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Glutathione metabolism" XP_014093649.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_014100745.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_014088306.1 10 KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1 "Carbon fixation in photosynthetic organisms";"Glycolysis";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_014088630.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_014091617.1 7 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "ATP biosynthesis";"Oxidative phosphorylation";"Mitochondrial protein import";"Photosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_014100643.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014096462.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014087739.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_014099744.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_014101790.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_014090095.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_014088945.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_014092051.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_014089006.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_014099349.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_014098249.1 6 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism" XP_014096716.1 4 Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_014097530.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014097656.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_014101006.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_014093124.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014100504.1 2 KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_014097357.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_014103446.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014100508.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-400253;Reactome: R-HSA-9020702;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-69231;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-2644606;Reactome: R-HSA-5610780;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-1170546;Reactome: R-HSA-5676590;Reactome: R-HSA-917937 "Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Circadian Clock";"Interleukin-1 signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Cyclin D associated events in G1";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI1 by the proteasome";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Prolactin receptor signaling";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport" XP_014092566.1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5392;KEGG: 00640+6.2.1.5 "C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Reductive TCA cycle II";"Propanoate metabolism" XP_014087152.1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_014095397.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_014095764.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-176187 "CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress" XP_014094057.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_014088900.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014100303.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014096951.1 10 Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-6317;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2 "Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_014095591.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_014090149.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014090462.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014098832.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_014091542.1 7 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_014092502.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_014098137.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_014100807.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_014098726.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_014101599.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_014094432.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_014087653.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_014089594.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_014086887.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_014103127.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_014085691.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68827 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex" XP_014088445.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014085354.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014088141.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" XP_014089365.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014090348.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_014102057.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014102156.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_014102889.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_014091254.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_014101771.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014093588.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_014091001.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_014102158.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_014089737.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits" XP_014100199.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096 "Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation" XP_014089799.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497;Reactome: R-HSA-9018519 "Attenuation phase";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Estrogen-dependent gene expression" XP_014086300.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_014094234.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_014085642.1 6 Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36 "Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism" XP_014096426.1 13 MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;Reactome: R-HSA-9027277;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis" XP_014089992.1 8 MetaCyc: PWY-6609;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217 "Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Surfactant metabolism";"Purine metabolism";"Purine salvage" XP_014085665.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_014101514.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014089899.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_014097793.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_014099404.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_014099829.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_014087737.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_014085562.1 12 MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13 "Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Pentose phosphate pathway";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism" XP_014088903.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_014097219.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-159231 "Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Viral Messenger RNA Synthesis";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_014095580.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_014090541.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_014102024.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_014099810.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport" XP_014086742.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_014086008.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014099965.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_014092995.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" XP_014091714.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_014094879.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014097164.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_014099386.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014085276.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014087692.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_014099059.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_014099482.1 8 KEGG: 00270+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27 "Cysteine and methionine metabolism";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" XP_014099424.1 14 Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_014091384.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_014090118.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014097881.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014102860.1 16 Reactome: R-HSA-1810476;Reactome: R-HSA-5603041;Reactome: R-HSA-975871;Reactome: R-HSA-3134963;Reactome: R-HSA-5603037;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-6811558;Reactome: R-HSA-166058;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702;Reactome: R-HSA-5602498;Reactome: R-HSA-209543;Reactome: R-HSA-975138 "RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)";"MyD88 cascade initiated on plasma membrane";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"IRAK4 deficiency (TLR5)";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling";"MyD88 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_014098432.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_014093553.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_014086271.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014093488.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_014096129.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_014095624.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_014090378.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_014087960.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_014092669.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_014087818.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_014094723.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_014097984.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_014096662.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_014088317.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_014085624.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_014089940.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_014089983.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_014095678.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014096038.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" XP_014092255.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_014101840.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_014098683.1 8 Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-5154;MetaCyc: PWY-5;KEGG: 00250+4.3.2.1;MetaCyc: PWY-7400 "Urea cycle";"Arginine biosynthesis";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Canavanine biosynthesis";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)" XP_014086007.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_014096811.1 5 Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-936440 "TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling" XP_014088226.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014089733.1 7 Reactome: R-HSA-168333;Reactome: R-HSA-203927;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-5578749 "NEP/NS2 Interacts with the Cellular Export Machinery";"MicroRNA (miRNA) biogenesis";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs" XP_014086912.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_014091346.1 5 Reactome: R-HSA-964975;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_014087837.1 22 Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5675221;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337 "Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Negative regulation of MAPK pathway";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding" XP_014099816.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_014088069.1 52 Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-167243;Reactome: R-HSA-167162;Reactome: R-HSA-168325;Reactome: R-HSA-76066;Reactome: R-HSA-5617472;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-73780;Reactome: R-HSA-72203;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-72163;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-76061;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167152;Reactome: R-HSA-749476;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-8851708;Reactome: R-HSA-6803529 "Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II HIV Promoter Escape";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"mRNA Splicing - Major Pathway";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Signaling by FGFR2 IIIa TM";"FGFR2 alternative splicing" XP_014103729.1 7 KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-5578999 "Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_014100524.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_014099196.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-983170;Reactome: R-HSA-381070;Reactome: R-HSA-381183 "Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes" XP_014092770.1 9 KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;Reactome: R-HSA-156590 "Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione conjugation" XP_014086373.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_014100049.1 4 Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258 "Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_014103685.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315 "Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_014087625.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_014090659.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014100893.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_014092428.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_014097371.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_014097066.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_014087626.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_014098969.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_014089778.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_014086941.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_014098918.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_014097930.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_014102447.1 1 MetaCyc: PWY-6938 "NADH repair" XP_014085361.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_014097899.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_014086166.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_014101343.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_014102471.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_014086274.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014095236.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_014097294.1 31 MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-8012;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-5994;MetaCyc: PWYG-321;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-2426168;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-5971;MetaCyc: PWY-7664;MetaCyc: PWY-7663;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)";"Biotin metabolism";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" XP_014097859.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_014089279.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_014099711.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_014099238.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_014097955.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_014089900.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria" XP_014098152.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_014091825.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_014087343.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_014086874.1 3 KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691 "Caffeine metabolism";"Purine metabolism";"Urate conversion to allantoin I" XP_014090940.1 8 Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750 "PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6" XP_014088732.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_014095490.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_014096032.1 4 Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_014100020.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_014091159.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_014098351.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_014089802.1 10 MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053 "Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_014103084.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_014100872.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_014100568.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_014089866.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_014098203.1 3 KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis" XP_014085411.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases" XP_014095677.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_014091080.1 9 Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001 "Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade"